Published in Pharmacol Ther on April 04, 2013
Osteoporosis Recovery by Antrodia camphorata Alcohol Extracts through Bone Regeneration in SAMP8 Mice. Evid Based Complement Alternat Med (2016) 1.39
Antrodin C inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via suppression of Smad2/3 and β-catenin signaling pathways. PLoS One (2015) 0.86
The functional influences of common ABCB1 genetic variants on the inhibition of P-glycoprotein by Antrodia cinnamomea extracts. PLoS One (2014) 0.82
The adjuvant effects of high-molecule-weight polysaccharides purified from Antrodia cinnamomea on dendritic cell function and DNA vaccines. PLoS One (2015) 0.81
Genomic and transcriptomic analyses of the medicinal fungus Antrodia cinnamomea for its metabolite biosynthesis and sexual development. Proc Natl Acad Sci U S A (2014) 0.80
Antrodia cinnamomea alleviates cisplatin-induced hepatotoxicity and enhances chemo-sensitivity of line-1 lung carcinoma xenografted in BALB/cByJ mice. Oncotarget (2015) 0.78
MicroRNA-like small RNAs prediction in the development of Antrodia cinnamomea. PLoS One (2015) 0.78
Identification and Cytotoxic Activities of Two New Trichothecenes and a New Cuparane-Type Sesquiterpenoid from the Cultures of the Mushroom Engleromyces goetzii. Nat Prod Bioprospect (2015) 0.77
Intestinal Absorption of Ergostane and Lanostane Triterpenoids from Antrodia cinnamomea Using Caco-2 Cell Monolayer Model. Nat Prod Bioprospect (2015) 0.75
Antcin H Protects Against Acute Liver Injury Through Disruption of the Interaction of c-Jun-N-Terminal Kinase with Mitochondria. Antioxid Redox Signal (2016) 0.75
Re-evaluation of the Genus Antrodia (Polyporales, Basidiomycota) in Korea. Mycobiology (2014) 0.75
A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1. Oncotarget (2016) 0.75
Genotoxic, teratotoxic and oral toxic assessments of Antrodia cinnamomea health food product (Leader Deluxe Antrodia cinnamomea(®)). Toxicol Rep (2015) 0.75
Potent inhibition of superoxide anion production in activated human neutrophils by isopedicin, a bioactive component of the Chinese medicinal herb Fissistigma oldhamii. Free Radic Biol Med (2008) 1.87
Cladielloides A and B: new eunicellin-type diterpenoids from an Indonesian octocoral Cladiella sp. Mar Drugs (2010) 1.50
The hederagenin saponin SMG-1 is a natural FMLP receptor inhibitor that suppresses human neutrophil activation. Biochem Pharmacol (2010) 1.47
A new anti-HIV alkaloid, drymaritin, and a new C-glycoside flavonoid, diandraflavone, from Drymaria diandra. J Nat Prod (2004) 1.42
Eunicellin-based diterpenoids, australins A-D, isolated from the soft coral Cladiella australis. J Nat Prod (2005) 1.36
Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes. Eur J Pharmacol (2003) 1.34
Cytotoxic and anti-inflammatory cembranoids from the soft coral Lobophytum crassum. J Nat Prod (2008) 1.33
Discovery of new eunicellins from an Indonesian octocoral Cladiella sp. Mar Drugs (2011) 1.32
Taxifolin ameliorates cerebral ischemia-reperfusion injury in rats through its anti-oxidative effect and modulation of NF-kappa B activation. J Biomed Sci (2005) 1.32
Paralemnolins J-P, new sesquiterpenoids from the soft coral Paralemnalia thyrsoide. Chem Pharm Bull (Tokyo) (2010) 1.30
Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents. J Med Chem (2006) 1.25
Klysimplexins I-T, eunicellin-based diterpenoids from the cultured soft coral Klyxum simplex. Org Biomol Chem (2010) 1.25
Synthesis of chalcone derivatives as potential anti-diabetic agents. Bioorg Med Chem Lett (2012) 1.25
The extracts from Nelumbo Nucifera suppress cell cycle progression, cytokine genes expression, and cell proliferation in human peripheral blood mononuclear cells. Life Sci (2004) 1.25
Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti-inflammatory effect. Br J Pharmacol (2002) 1.24
Hirsutalins A-H, eunicellin-based diterpenoids from the soft coral Cladiella hirsuta. J Nat Prod (2010) 1.23
Antioxidant activities of extracts and main components of Pigeonpea [Cajanus cajan (L.) Millsp.] leaves. Molecules (2009) 1.23
Honokiol protects rat brain from focal cerebral ischemia-reperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production. Brain Res (2003) 1.21
The anti-inflammatory effect of honokiol on neutrophils: mechanisms in the inhibition of reactive oxygen species production. Eur J Pharmacol (2003) 1.20
Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties. Cancer Cell Int (2013) 1.19
Crassolides A-F, cembranoids with a trans-fused lactone from the soft coral Sarcophyton crassocaule. J Nat Prod (2006) 1.18
Bioactive cembranoids from the soft coral Sinularia crassa. Mar Drugs (2011) 1.18
Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells. Cancer Lett (2009) 1.18
Hirsutosterols A-G, polyoxygenated steroids from a Formosan soft coral Cladiella hirsuta. Org Biomol Chem (2011) 1.16
Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells. Eur J Pharmacol (2006) 1.15
Evaluation of the anti-inflammatory activity of zhankuic acids isolated from the fruiting bodies of Antrodia camphorata. Planta Med (2004) 1.13
Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress. BMC Complement Altern Med (2012) 1.12
Oxygenated cembranoids from a Formosan soft coral Sinularia gibberosa. J Nat Prod (2008) 1.12
Klymollins A-H, bioactive eunicellin-based diterpenoids from the formosan soft coral Klyxum molle. J Nat Prod (2011) 1.11
Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondria. Mol Cancer Ther (2005) 1.11
Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis. Food Chem Toxicol (2012) 1.10
Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells. Cell Signal (2011) 1.09
Automatic morphological subtyping reveals new roles of caspases in mitochondrial dynamics. PLoS Comput Biol (2011) 1.08
Antitumor agents. 228. five new agarofurans, Reissantins A-E, and cytotoxic principles from Reissantia buchananii. J Nat Prod (2003) 1.07
Association of ORAI1 haplotypes with the risk of HLA-B27 positive ankylosing spondylitis. PLoS One (2011) 1.07
Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida. J Nat Prod (2009) 1.06
4beta-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest. BMC Cancer (2010) 1.06
Acetogenins as selective inhibitors of the human ovarian 1A9 tumor cell line. J Med Chem (2003) 1.05
Antiproliferation and induction of apoptosis in Ca9-22 oral cancer cells by ethanolic extract of Gracilaria tenuistipitata. Molecules (2012) 1.05
Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction. Mutat Res (2012) 1.03
Paraminabeolides A-F, cytotoxic and anti-inflammatory marine withanolides from the soft coral Paraminabea acronocephala. J Nat Prod (2011) 1.02
Steroids from the soft coral Sinularia crassa. Mar Drugs (2012) 1.02
Possible involvement of nitric oxide in the progression of diabetic retinopathy. Ophthalmologica (2003) 1.01
Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis, and reduced migration ability. J Agric Food Chem (2011) 1.00
New ent-kaurane diterpenoids with anti-platelet aggregation activity from Annona squamosa. J Nat Prod (2002) 1.00
Inhibitory effects of 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose on biofilm formation by Staphylococcus aureus. Antimicrob Agents Chemother (2010) 0.99
Towards the small and the beautiful: a small dibromotyrosine derivative from Pseudoceratina sp. sponge exhibits potent apoptotic effect through targeting IKK/NFκB signaling pathway. Mar Drugs (2013) 0.99
Glycolipids from the formosan soft coral Lobophytum crassum. Chem Pharm Bull (Tokyo) (2007) 0.99
Polyoxygenated steroids from the gorgonian Isis hippuris. J Nat Prod (2005) 0.98
Anxiolytic-like effects of baicalein and baicalin in the Vogel conflict test in mice. Eur J Pharmacol (2003) 0.98
Cytotoxicity of phenolic acid phenethyl esters on oral cancer cells. Cancer Lett (2004) 0.98
Fern plant-derived protoapigenone leads to DNA damage, apoptosis, and G(2)/m arrest in lung cancer cell line H1299. DNA Cell Biol (2009) 0.97
An epigenetic modifier enhances the production of anti-diabetic and anti-inflammatory sesquiterpenoids from Aspergillus sydowii. Bioorg Med Chem (2013) 0.97
Enhanced survival and regeneration of axotomized retinal ganglion cells by a mixture of herbal extracts. J Neurotrauma (2002) 0.97
Anti-hepatitis C virus activity of Acacia confusa extract via suppressing cyclooxygenase-2. Antiviral Res (2010) 0.97
Constituents of Polyalthia longifolia var. pendula. J Nat Prod (2009) 0.97
Tubocapsenolide A, a novel withanolide, inhibits proliferation and induces apoptosis in MDA-MB-231 cells by thiol oxidation of heat shock proteins. J Biol Chem (2008) 0.97
Cytotoxic and anti-inflammatory metabolites from the soft coral Scleronephthya gracillimum. Mar Drugs (2013) 0.96
New cytotoxic flavonoids from Thelypteris torresiana. Planta Med (2005) 0.96
First total synthesis of protoapigenone and its analogues as potent cytotoxic agents. J Med Chem (2007) 0.96
Discovery of new eunicellin-based diterpenoids from a Formosan soft coral Cladiella sp. Mar Drugs (2013) 0.95
New cytotoxic cyclic peptides and dianthramide from Dianthus superbus. J Nat Prod (2004) 0.95
A C-3 methylated isocembranoid and 10-oxocembranoids from a formosan soft coral, Sinularia grandilobata. J Nat Prod (2008) 0.95
A triterpenoid methyl antcinate K isolated from Antrodia cinnamomea promotes dendritic cell activation and Th2 differentiation. Eur J Immunol (2009) 0.95
Cytotoxic calanquinone A from Calanthe arisanensis and its first total synthesis. Bioorg Med Chem Lett (2008) 0.95
9,11-Secosterols from the soft corals Sinularia lochmodes and Sinularia leptoclados. J Nat Prod (2006) 0.95
Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components. Chin Med (2011) 0.94
Synthesis and pharmacological evaluation of novel beta-nitrostyrene derivatives as tyrosine kinase inhibitors with potent antiplatelet activity. Biochem Pharmacol (2007) 0.94
Historic perspectives on Annonaceous acetogenins from the chemical bench to preclinical trials. Planta Med (2010) 0.93
Mediation of Endogenous beta-endorphin by Tetrandrine to Lower Plasma Glucose in Streptozotocin-induced Diabetic Rats. Evid Based Complement Alternat Med (2004) 0.93
Molluscicidal saponins from Sapindus mukorossi, inhibitory agents of golden apple snails, Pomacea canaliculata. J Agric Food Chem (2003) 0.93
Anti-inflammatory and cytotoxic diterpenes from formosan Polyalthia longifolia var. pendula. Planta Med (2006) 0.93
Antitumor agents. 271: total synthesis and evaluation of brazilein and analogs as anti-inflammatory and cytotoxic agents. Bioorg Med Chem Lett (2009) 0.93