Published in PLoS One on April 03, 2013
Metabolomics and diabetes: analytical and computational approaches. Diabetes (2015) 0.90
A Metabolomic Approach to Understanding the Metabolic Link between Obesity and Diabetes. Mol Cells (2015) 0.87
Metabonomic analysis of potential biomarkers and drug targets involved in diabetic nephropathy mice. Sci Rep (2015) 0.82
¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet. PLoS One (2015) 0.80
Metabolomic insights into the intricate gut microbial-host interaction in the development of obesity and type 2 diabetes. Front Microbiol (2015) 0.80
A 1H-NMR Based Study on Hemolymph Metabolomics in Eri Silkworm after Oral Administration of 1-Deoxynojirimycin. PLoS One (2015) 0.78
1HNMR-based metabolomic profile of rats with experimental acute pancreatitis. BMC Gastroenterol (2014) 0.77
An Evaluation of 1-Deoxynojirimycin Oral Administration in Eri Silkworm through Fat Body Metabolomics Based on (1) H Nuclear Magnetic Resonance. Biomed Res Int (2016) 0.77
Identification of key metabolic changes in renal interstitial fibrosis rats using metabonomics and pharmacology. Sci Rep (2016) 0.76
Detection of driver metabolites in the human liver metabolic network using structural controllability analysis. BMC Syst Biol (2014) 0.75
Metabolite changes in the ipsilateral and contralateral cerebral hemispheres in rats with middle cerebral artery occlusion. Neural Regen Res (2017) 0.75
'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica (1999) 9.04
The acetate switch. Microbiol Mol Biol Rev (2005) 6.10
Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat. Annu Rev Immunol (1990) 3.35
Diabetogenic action of streptozotocin: relationship of dose to metabolic response. J Clin Invest (1969) 3.16
Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes. Proc Natl Acad Sci U S A (2005) 2.70
A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human. Physiol Genomics (2006) 2.10
Rodent models of streptozotocin-induced diabetic nephropathy. Nephrology (Carlton) (2007) 1.88
An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse. FEBS Lett (2000) 1.74
Discovery of metabolomics biomarkers for early detection of nephrotoxicity. Toxicol Pathol (2009) 1.64
Inhibition of glucose uptake and glycogenolysis by availability of oleate in well-oxygenated perfused skeletal muscle. Biochem J (1977) 1.61
Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes. PLoS One (2010) 1.53
Origins of blood acetate in the rat. Biochem J (1977) 1.48
Increased renal metabolism in diabetes. Mechanism and functional implications. Diabetes (1994) 1.36
The role of taurine in diabetes and the development of diabetic complications. Diabetes Metab Res Rev (2001) 1.36
The origin of urinary dimethylamine. Biochim Biophys Acta (1965) 1.32
Interorgan metabolism of amino acids in streptozotocin-diabetic ketoacidotic rat. Am J Physiol (1983) 1.29
Gender-related and age-related urinalysis of healthy subjects by NMR-based metabonomics. NMR Biomed (2008) 1.25
Increased energy expenditure in poorly controlled Type 1 (insulin-dependent) diabetic patients. Diabetologia (1984) 1.21
The taurine transporter: mechanisms of regulation. Acta Physiol (Oxf) (2006) 1.20
Correlative and quantitative 1H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats. Anal Biochem (2008) 1.20
The metabonomics of aging and development in the rat: an investigation into the effect of age on the profile of endogenous metabolites in the urine of male rats using 1H NMR and HPLC-TOF MS. Mol Biosyst (2005) 1.15
Metabonomic profiling of renal cell carcinoma: high-resolution proton nuclear magnetic resonance spectroscopy of human serum with multivariate data analysis. Anal Chim Acta (2008) 1.14
Discrimination of Type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 1.14
Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers. Br J Clin Pharmacol (2007) 1.09
The in vivo and in vitro protective properties of taurine. Gen Pharmacol (1995) 1.05
Glucose-induced metabolic imbalances in the pathogenesis of diabetic vascular disease. Diabetes Metab Rev (1991) 0.99
An optimized buffer system for NMR-based urinary metabonomics with effective pH control, chemical shift consistency and dilution minimization. Analyst (2009) 0.99
Protective Effects of Green Tea Extract against Hepatic Tissue Injury in Streptozotocin-Induced Diabetic Rats. Evid Based Complement Alternat Med (2012) 0.94
Proton nuclear magnetic resonance spectral profiles of urine in type II diabetic patients. Clin Chem (1998) 0.93
The comparative metabonomics of age-related changes in the urinary composition of male Wistar-derived and Zucker (fa/fa) obese rats. Mol Biosyst (2006) 0.92
Current challenges in metabolomics for diabetes research: a vital functional genomic tool or just a ploy for gaining funding? Physiol Genomics (2008) 0.91
Urinary excretion of zinc, copper and iron in the streptozotocin-diabetic rat. J Nutr (1984) 0.91
Metabolic profile of the hippocampus of Zucker Diabetic Fatty rats assessed by in vivo 1H magnetic resonance spectroscopy. NMR Biomed (2004) 0.91
A metabonomic comparison of urinary changes in Zucker and GK rats. J Biomed Biotechnol (2010) 0.90
Progressive changes in lens crystallin glycation and high-molecular-weight aggregate formation leading to cataract development in streptozotocin-diabetic rats. Exp Eye Res (1987) 0.89
1H NMR-based metabonomic analysis of metabolic changes in streptozotocin-induced diabetic rats. Anal Sci (2010) 0.89
¹H-NMR-based metabonomic analysis of metabolic profiling in diabetic nephropathy rats induced by streptozotocin. Am J Physiol Renal Physiol (2011) 0.84
Nutritional aspects of amino acid metabolism. 3. The effects of diabetes on blood and liver amino acid concentrations in the rat. Br J Nutr (1972) 0.83
Metabonomics studies of intact hepatic and renal cortical tissues from diabetic db/db mice using high-resolution magic-angle spinning 1H NMR spectroscopy. Anal Bioanal Chem (2009) 0.83
A metabonomic study of biochemical changes characteristic of genetically hypertensive rats based on (1)H NMR spectroscopic urinalysis. Hypertens Res (2011) 0.81
Epigenetics of diabetic complications. Expert Rev Endocrinol Metab (2010) 0.80
Renal excretion of allantoin in rats: a micropuncture and clearance study. Am J Physiol (1977) 0.78
Metabonomics and diabetes mellitus. Adv Ther (2007) 0.76
Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling. Circulation (2006) 2.55
FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases. Proc Natl Acad Sci U S A (2007) 2.08
Hemodynamic correlates of blood pressure across the adult age spectrum: noninvasive evaluation in the Framingham Heart Study. Circulation (2010) 2.07
Bis(2-amino-3H-benzothia-zolium) bis-(7-oxabicyclo-[2.2.1]heptane-2,3-dicarboxyl-ato)cobaltate(II) hexa-hydrate. Acta Crystallogr Sect E Struct Rep Online (2010) 1.59
Bis(2-amino-3H-benzothia-zolium) bis-(7-oxabicyclo-[2.2.1]heptane-2,3-di-carbox-yl-ato)manganate(II) hexa-hydrate. Acta Crystallogr Sect E Struct Rep Online (2010) 1.57
Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial. Ann Intern Med (2016) 1.47
HIV incidence and associated factors in a cohort of men who have sex with men in Nanjing, China. Sex Transm Dis (2010) 1.47
Genome characterization of the oleaginous fungus Mortierella alpina. PLoS One (2011) 1.43
The Wnt coreceptor Ryk regulates Wnt/planar cell polarity by modulating the degradation of the core planar cell polarity component Vangl2. J Biol Chem (2012) 1.39
Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer. BMC Cancer (2012) 1.39
Retracted Analysis of the TCR alpha and beta chain CDR3 spectratypes in the peripheral blood of patients with Systemic Lupus Erythematosus. J Autoimmune Dis (2008) 1.38
The histone demethylase RBP2 Is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells. Gastroenterology (2009) 1.29
Ischemic postconditioning protects brain from ischemia/reperfusion injury by attenuating endoplasmic reticulum stress-induced apoptosis through PI3K-Akt pathway. Brain Res (2010) 1.19
The incidence of syphilis, HIV and HCV and associated factors in a cohort of men who have sex with men in Nanjing, China. Sex Transm Infect (2011) 1.18
Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North China. Carcinogenesis (2004) 1.18
Relation of circulating liver transaminase concentrations to risk of new-onset atrial fibrillation. Am J Cardiol (2012) 1.17
Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells. BMC Cancer (2012) 1.17
The functional polymorphism in the matrix metalloproteinase-7 promoter increases susceptibility to esophageal squamous cell carcinoma, gastric cardiac adenocarcinoma and non-small cell lung carcinoma. Carcinogenesis (2005) 1.12
Effects of cranberry juice consumption on vascular function in patients with coronary artery disease. Am J Clin Nutr (2011) 1.11
Youth alcohol use and dating abuse victimization and perpetration: a test of the relationships at the daily level in a sample of pediatric emergency department patients who use alcohol. J Interpers Violence (2012) 1.11
Prognostic significance of aberrant gene methylation in gastric cancer. Am J Cancer Res (2011) 1.10
Amperometric third-generation hydrogen peroxide biosensor based on the immobilization of hemoglobin on multiwall carbon nanotubes and gold colloidal nanoparticles. Biosens Bioelectron (2006) 1.08
Artificial gynogenesis and sex determination in half-smooth tongue sole (Cynoglossus semilaevis). Mar Biotechnol (NY) (2008) 1.08
MiR-429 up-regulation induces apoptosis and suppresses invasion by targeting Bcl-2 and SP-1 in esophageal carcinoma. Cell Oncol (Dordr) (2013) 1.07
Determination of the volatile composition in essential oil of Descurainia sophia (L.) Webb ex Prantl (Flixweed) by gas chromatography/mass spectrometry (GC/MS). Molecules (2010) 1.04
Forward and backward wave morphology and central pressure augmentation in men and women in the Framingham Heart Study. Hypertension (2014) 1.02
Polymorphisms in the promoter regions of the matrix metalloproteinases-1, -3, -7, and -9 and the risk of epithelial ovarian cancer in China. Gynecol Oncol (2005) 1.02
The functional SNP in the matrix metalloproteinase-3 promoter modifies susceptibility and lymphatic metastasis in esophageal squamous cell carcinoma but not in gastric cardiac adenocarcinoma. Carcinogenesis (2004) 1.01
Frequent gene amplification predicts poor prognosis in gastric cancer. Int J Mol Sci (2012) 1.00
Remote ischemic postconditioning protects the brain from global cerebral ischemia/reperfusion injury by up-regulating endothelial nitric oxide synthase through the PI3K/Akt pathway. Brain Res (2012) 1.00
Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase. FASEB J (2009) 1.00
Miniaturized liquid-liquid extraction coupled with ultra-performance liquid chromatography/tandem mass spectrometry for determination of topramezone in soil, corn, wheat, and water. Anal Bioanal Chem (2011) 1.00
Rapamycin preserves the follicle pool reserve and prolongs the ovarian lifespan of female rats via modulating mTOR activation and sirtuin expression. Gene (2013) 0.99
Systemic metabolic changes of traumatic critically ill patients revealed by an NMR-based metabonomic approach. J Proteome Res (2009) 0.99
Association of functional polymorphisms in MMPs genes with gastric cardia adenocarcinoma and esophageal squamous cell carcinoma in high incidence region of North China. Mol Biol Rep (2009) 0.99
Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant. J Clin Invest (2013) 0.98
Electrocardiographic PR interval and adverse outcomes in older adults: the Health, Aging, and Body Composition study. Circ Arrhythm Electrophysiol (2012) 0.98
Quantitative photoelectrochemical detection of biological affinity reaction: biotin-avidin interaction. Anal Chem (2004) 0.96
Identification of a uromodulin fragment for diagnosis of IgA nephropathy. Rapid Commun Mass Spectrom (2010) 0.96
Polymorphisms in tumor necrosis factor genes and susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma in a population of high incidence region of North China. Chin Med J (Engl) (2005) 0.95
Single nucleotide polymorphism in DNA methyltransferase 3B promoter and its association with gastric cardiac adenocarcinoma in North China. World J Gastroenterol (2005) 0.95
Addition of inflammatory biomarkers did not improve diabetes prediction in the community: the framingham heart study. J Am Heart Assoc (2012) 0.95
Quantitative assessment of gene methylation and their impact on clinical outcome in gastric cancer. Clin Chim Acta (2012) 0.94
Establishment and characterization of a testicular cell line from the half-smooth tongue sole, Cynoglossus semilaevis. Int J Biol Sci (2011) 0.94
The activating TERT promoter mutation C228T is recurrent in subsets of adrenal tumors. Endocr Relat Cancer (2014) 0.94
Prognostic value of cancer stem cell marker aldehyde dehydrogenase in ovarian cancer: a meta-analysis. PLoS One (2013) 0.93
MTL-independent phenotypic switching in Candida tropicalis and a dual role for Wor1 in regulating switching and filamentation. PLoS Genet (2013) 0.93
Sevoflurane postconditioning involves an up-regulation of HIF-1α and HO-1 expression via PI3K/Akt pathway in a rat model of focal cerebral ischemia. Brain Res (2012) 0.93
Identification of IL18RAP/IL18R1 and IL12B as leprosy risk genes demonstrates shared pathogenesis between inflammation and infectious diseases. Am J Hum Genet (2012) 0.92
Diabetes-induced hepatic pathogenic damage, inflammation, oxidative stress, and insulin resistance was exacerbated in zinc deficient mouse model. PLoS One (2012) 0.92
Polymorphisms of the DNA repair gene XPA and XPC and its correlation with gastric cardiac adenocarcinoma in a high incidence population in North China. J Clin Gastroenterol (2008) 0.92
Polymorphisms of the DNA repair gene xeroderma pigmentosum groups A and C and risk of esophageal squamous cell carcinoma in a population of high incidence region of North China. J Cancer Res Clin Oncol (2007) 0.92
Effect of miR-451 on the biological behavior of the esophageal carcinoma cell line EC9706. Dig Dis Sci (2012) 0.92
Clinical correlates of change in inflammatory biomarkers: The Framingham Heart Study. Atherosclerosis (2013) 0.92
Chiral triazole fungicide difenoconazole: absolute stereochemistry, stereoselective bioactivity, aquatic toxicity, and environmental behavior in vegetables and soil. Environ Sci Technol (2013) 0.92
Comparative study of solitary thin-walled cavity lung cancer with computed tomography and pathological findings. Lung Cancer (2012) 0.91
Cardiac protection by basic fibroblast growth factor from ischemia/reperfusion-induced injury in diabetic rats. Biol Pharm Bull (2010) 0.90
Association of MTHFR C677T and SHMT(1) C1420T with susceptibility to ESCC and GCA in a high incident region of Northern China. Cancer Causes Control (2007) 0.90
Association of polymorphisms -1154G/A and -2578C/A in the vascular endothelial growth factor gene with decreased risk of endometriosis in Chinese women. Hum Reprod (2009) 0.89
Zinc supplementation partially prevents renal pathological changes in diabetic rats. J Nutr Biochem (2009) 0.89
Hypoxia can contribute to the induction of the Epstein-Barr virus (EBV) lytic cycle. J Clin Virol (2006) 0.89
1H NMR-based metabonomic analysis of metabolic changes in streptozotocin-induced diabetic rats. Anal Sci (2010) 0.89
Polymorphisms in promoter region of FAS and FASL gene and risk of cardia gastric adenocarcinoma. J Gastroenterol Hepatol (2010) 0.89
Association of the thymidylate synthase polymorphisms with esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma. Carcinogenesis (2004) 0.89
Bioassay based luminescent bacteria: interferences, improvements, and applications. Sci Total Environ (2013) 0.88
Association of p73 and MDM2 polymorphisms with the risk of epithelial ovarian cancer in Chinese women. Int J Gynecol Cancer (2009) 0.88
Environmental behavior of the chiral triazole fungicide fenbuconazole and its chiral metabolites: enantioselective transformation and degradation in soils. Environ Sci Technol (2012) 0.88
Association of polymorphisms of the MMP-2 and TIMP-2 genes with the risk of endometriosis in North Chinese women. Fertil Steril (2008) 0.88
Diaqua-bis(ciprofloxacinato)manganese(II) 2,2'-bipyridine solvate tetrahydrate. Acta Crystallogr Sect E Struct Rep Online (2009) 0.88
Optimization of covalent immobilization of pectinase on sodium alginate support. Biotechnol Lett (2007) 0.88
Association of sex hormones, aging, and atrial fibrillation in men: the Framingham Heart Study. Circ Arrhythm Electrophysiol (2014) 0.87
BioSunMS: a plug-in-based software for the management of patients information and the analysis of peptide profiles from mass spectrometry. BMC Med Inform Decis Mak (2009) 0.87
No association of the matrix metalloproteinase 1 promoter polymorphism with susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma in northern China. World J Gastroenterol (2005) 0.87
Systemic and characteristic metabolites in the serum of streptozotocin-induced diabetic rats at different stages as revealed by a (1)H-NMR based metabonomic approach. Mol Biosyst (2014) 0.87
Analysis of HAX-1 gene expression in esophageal squamous cell carcinoma. Diagn Pathol (2013) 0.87
MiR-9 inhibits Schwann cell migration by targeting Cthrc1 following sciatic nerve injury. J Cell Sci (2014) 0.87
Immunoproteomics of extracellular proteins of the Aeromonas hydrophila China vaccine strain J-1 reveal a highly immunoreactive outer membrane protein. FEMS Immunol Med Microbiol (2010) 0.86
Interleukin-10 -1082 promoter polymorphism is not associated with susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma in a population of high-incidence region of north China. World J Gastroenterol (2005) 0.86
Association of the DNMT3B polymorphism with colorectal adenomatous polyps and adenocarcinoma. Mol Biol Rep (2009) 0.86
Genetic polymorphisms in the Fas and FasL genes are associated with epithelial ovarian cancer risk and clinical outcomes. Gynecol Oncol (2012) 0.86
Hepatopoietin interacts directly with COP9 signalosome and regulates AP-1 activity. FEBS Lett (2004) 0.86
Identification of complement C3f-desArg and its derivative for acute leukemia diagnosis and minimal residual disease assessment. Proteomics (2010) 0.86
Genetic polymorphism in the 3'-untranslated region of the E-cadherin gene is associated with risk of different cancers. Mol Carcinog (2011) 0.86
Borna disease virus infection perturbs energy metabolites and amino acids in cultured human oligodendroglia cells. PLoS One (2012) 0.86
[Factors associated with HIV infection among men who have sex with men in Nanjing, Suzhou and Yangzhou: a 1:4 matched case-control study]. Zhonghua Liu Xing Bing Xue Za Zhi (2009) 0.86
No association between the C-1562T polymorphism in the promoter of matrix metalloproteinase-9 gene and non-small cell lung carcinoma. Lung Cancer (2005) 0.86
Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells. Oncol Rep (2012) 0.86
Effects of decabrominated diphenyl ether (PBDE-209) in regulation of growth and apoptosis of breast, ovarian, and cervical cancer cells. Environ Health Perspect (2012) 0.86
Purification of recombinant laccase from Trametes versicolor in Pichia methanolica and its use for the decolorization of anthraquinone dye. Biotechnol Lett (2008) 0.86
NF-κB and enhancer-binding CREB protein scaffolded by CREB-binding protein (CBP)/p300 proteins regulate CD59 protein expression to protect cells from complement attack. J Biol Chem (2013) 0.86
Phosphorylation-triggered CUEDC2 degradation promotes UV-induced G1 arrest through APC/C(Cdh1) regulation. Proc Natl Acad Sci U S A (2013) 0.85
Signal transduction mechanism of TRB3 in rats with non-alcoholic fatty liver disease. World J Gastroenterol (2009) 0.85
Establishment and characterization of a new fish cell line from head kidney of half-smooth tongue sole (Cynoglossus semilaevis). Fish Physiol Biochem (2012) 0.84
Thoracic periaortic and visceral adipose tissue and their cross-sectional associations with measures of vascular function. Obesity (Silver Spring) (2013) 0.84
The functional polymorphisms on promoter region of matrix metalloproteinase-12, -13 genes may alter the risk of epithelial ovarian carcinoma in Chinese. Int J Gynecol Cancer (2009) 0.84
Pericardial fat is associated with atrial conduction: the Framingham Heart Study. J Am Heart Assoc (2014) 0.84
Lactobacillus casei Zhang modulate cytokine and toll-like receptor expression and beneficially regulate poly I:C-induced immune responses in RAW264.7 macrophages. Microbiol Immunol (2013) 0.84
[Correlation of XPC Ala499Val and Lys939Gln polymorphisms to risks of esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma]. Ai Zheng (2006) 0.84