| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes.
|
N Engl J Med
|
2011
|
11.11
|
|
2
|
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death.
|
Nat Genet
|
2003
|
4.19
|
|
3
|
A common polymorphism in the 5'-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes.
|
Diabetes
|
2002
|
2.46
|
|
4
|
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1.
|
J Biol Chem
|
2004
|
2.29
|
|
5
|
Is the diagnosis of metabolic syndrome useful for predicting cardiovascular disease in asian diabetic patients? Analysis from the Japan Diabetes Complications Study.
|
Diabetes Care
|
2005
|
1.85
|
|
6
|
The long-term effects of self-management education for patients with type 2 diabetes on glycemic control: response to Norris et al.
|
Diabetes Care
|
2002
|
1.78
|
|
7
|
Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis.
|
J Clin Endocrinol Metab
|
2007
|
1.57
|
|
8
|
Combinations of olmesartan and a calcium channel blocker or a diuretic in elderly hypertensive patients: a randomized, controlled trial.
|
J Hypertens
|
2014
|
1.56
|
|
9
|
Prevention of transition from incipient to overt nephropathy with telmisartan in patients with type 2 diabetes.
|
Diabetes Care
|
2007
|
1.50
|
|
10
|
Preclinical Cushing's syndrome due to ACTH-independent bilateral macronodular adrenocortical hyperplasia with excessive secretion of 18-hydroxydeoxycorticosterone and corticosterone.
|
Intern Med
|
2002
|
1.41
|
|
11
|
Noninvasive evaluation of kidney hypoxia and fibrosis using magnetic resonance imaging.
|
J Am Soc Nephrol
|
2011
|
1.41
|
|
12
|
Serum level of triglycerides is a potent risk factor comparable to LDL cholesterol for coronary heart disease in Japanese patients with type 2 diabetes: subanalysis of the Japan Diabetes Complications Study (JDCS).
|
J Clin Endocrinol Metab
|
2011
|
1.26
|
|
13
|
Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population.
|
Ophthalmology
|
2010
|
1.26
|
|
14
|
Preventing microalbuminuria in patients with diabetes: rationale and design of the Randomised Olmesartan and Diabetes Microalbuminuria Prevention (ROADMAP) study.
|
J Hypertens
|
2006
|
1.25
|
|
15
|
Association of type 1 diabetes with two Loci on 12q13 and 16p13 and the influence coexisting thyroid autoimmunity in Japanese.
|
J Clin Endocrinol Metab
|
2008
|
1.24
|
|
16
|
Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes.
|
Biochem Biophys Res Commun
|
2005
|
1.19
|
|
17
|
Disruption of the murine intestinal alkaline phosphatase gene Akp3 impairs lipid transcytosis and induces visceral fat accumulation and hepatic steatosis.
|
Am J Physiol Gastrointest Liver Physiol
|
2007
|
1.17
|
|
18
|
CLOCK/BMAL1 is involved in lipid metabolism via transactivation of the peroxisome proliferator-activated receptor (PPAR) response element.
|
J Atheroscler Thromb
|
2005
|
1.15
|
|
19
|
Prevalence and risk factors for erectile dysfunction in Japanese diabetics.
|
Diabetes Res Clin Pract
|
2005
|
1.15
|
|
20
|
Coding and noncoding variants in the CFH gene and cigarette smoking influence the risk of age-related macular degeneration in a Japanese population.
|
Invest Ophthalmol Vis Sci
|
2007
|
1.13
|
|
21
|
Endothelial nitric oxide synthase gene is associated with diabetic macular edema in type 2 diabetes.
|
Diabetes Care
|
2004
|
1.12
|
|
22
|
Predicting macro- and microvascular complications in type 2 diabetes: the Japan Diabetes Complications Study/the Japanese Elderly Diabetes Intervention Trial risk engine.
|
Diabetes Care
|
2013
|
1.02
|
|
23
|
LKB1, an upstream AMPK kinase, regulates glucose and lipid metabolism in cultured liver and muscle cells.
|
Biochem Biophys Res Commun
|
2006
|
1.02
|
|
24
|
Complement factor H and high-temperature requirement A-1 genotypes and treatment response of age-related macular degeneration.
|
Ophthalmology
|
2010
|
1.01
|
|
25
|
A case of primary mucoepidermoid carcinoma of the thyroid: molecular evidence of its origin.
|
Clin Endocrinol (Oxf)
|
2002
|
0.98
|
|
26
|
Comparison of various lipid variables as predictors of coronary heart disease in Japanese men and women with type 2 diabetes: subanalysis of the Japan Diabetes Complications Study.
|
Diabetes Care
|
2012
|
0.98
|
|
27
|
Components of metabolic syndrome and their combinations as predictors of cardiovascular disease in Japanese patients with type 2 diabetes. Implications for improved definition. Analysis from Japan Diabetes Complications Study (JDCS).
|
J Atheroscler Thromb
|
2009
|
0.96
|
|
28
|
Rationale, study design and implementation of the COLM study: the combination of OLMesartan and calcium channel blocker or diuretic in high-risk elderly hypertensive patients.
|
Hypertens Res
|
2009
|
0.95
|
|
29
|
Activating effect of benzbromarone, a uricosuric drug, on peroxisome proliferator-activated receptors.
|
PPAR Res
|
2007
|
0.95
|
|
30
|
Regulation of adiponectin receptor gene expression in diabetic mice.
|
Am J Physiol Endocrinol Metab
|
2004
|
0.94
|
|
31
|
A promoter in the novel exon of hPPARgamma directs the circadian expression of PPARgamma.
|
J Atheroscler Thromb
|
2010
|
0.94
|
|
32
|
Waist circumference as a cardiovascular and metabolic risk in Japanese patients with type 2 diabetes.
|
Obesity (Silver Spring)
|
2008
|
0.93
|
|
33
|
Associations of cigarette smoking but not serum fatty acids with age-related macular degeneration in a Japanese population.
|
Ophthalmology
|
2011
|
0.91
|
|
34
|
Insulin gene/IDDM2 locus in Japanese type 1 diabetes: contribution of class I alleles and influence of class I subdivision in susceptibility to type 1 diabetes.
|
J Clin Endocrinol Metab
|
2007
|
0.91
|
|
35
|
Risk of cardiovascular diseases is increased even with mild diabetic retinopathy: the Japan Diabetes Complications Study.
|
Ophthalmology
|
2012
|
0.90
|
|
36
|
Regulation of PPAR gamma transcriptional activity in 3T3-L1 adipocytes.
|
Biochem Biophys Res Commun
|
2003
|
0.89
|
|
37
|
Promoter polymorphisms of the pigment epithelium-derived factor gene are associated with diabetic retinopathy.
|
Biochem Biophys Res Commun
|
2007
|
0.88
|
|
38
|
Induction of heme oxygenase-1 in monocytes suppresses angiotensin II-elicited chemotactic activity through inhibition of CCR2: role of bilirubin and carbon monoxide generated by the enzyme.
|
Antioxid Redox Signal
|
2003
|
0.87
|
|
39
|
Stimulation of thyroid-stimulating hormone (TSH) receptor antibody production following painless thyroiditis.
|
Clin Endocrinol (Oxf)
|
2004
|
0.87
|
|
40
|
Heme oxygenase-1 in vascular smooth muscle cells counteracts cardiovascular damage induced by angiotensin II.
|
Curr Neurovasc Res
|
2005
|
0.87
|
|
41
|
Microalbuminuria reduction with telmisartan in normotensive and hypertensive Japanese patients with type 2 diabetes: a post-hoc analysis of The Incipient to Overt: Angiotensin II Blocker, Telmisartan, Investigation on Type 2 Diabetic Nephropathy (INNOVATION) study.
|
Hypertens Res
|
2008
|
0.87
|
|
42
|
Free immunoglobulin light chain: its biology and implications in diseases.
|
Clin Chim Acta
|
2011
|
0.87
|
|
43
|
Lysophosphatidylcholine for efficient intestinal lipid absorption and lipoprotein secretion in caco-2 cells.
|
J Clin Biochem Nutr
|
2009
|
0.86
|
|
44
|
Erectile dysfunction in hypertensive rats results from impairment of the relaxation evoked by neurogenic carbon monoxide and nitric oxide.
|
Hypertens Res
|
2004
|
0.86
|
|
45
|
Combined treatment with an AT1 receptor blocker and angiotensin converting enzyme inhibitor has an additive effect on inhibiting neointima formation via improvement of nitric oxide production and suppression of oxidative stress.
|
Hypertens Res
|
2004
|
0.86
|
|
46
|
Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues.
|
Biochem Biophys Res Commun
|
2008
|
0.86
|
|
47
|
Carboxy terminus of glucose transporter 3 contains an apical membrane targeting domain.
|
Mol Endocrinol
|
2003
|
0.85
|
|
48
|
ANGPTL3 is increased in both insulin-deficient and -resistant diabetic states.
|
Biochem Biophys Res Commun
|
2004
|
0.84
|
|
49
|
Efficacy of glimepiride in Japanese type 2 diabetic subjects.
|
Diabetes Res Clin Pract
|
2004
|
0.84
|
|
50
|
Analysis of the HLA and non-HLA susceptibility loci in Japanese type 1 diabetes.
|
Diabetes Metab Res Rev
|
2011
|
0.84
|
|
51
|
Clostridium butyricum MIYAIRI 588 improves high-fat diet-induced non-alcoholic fatty liver disease in rats.
|
Dig Dis Sci
|
2013
|
0.84
|
|
52
|
Effects of a low dose of indapamide, a diuretic, given daily or every-other-day on blood pressure and metabolic parameters.
|
Hypertens Res
|
2004
|
0.84
|
|
53
|
Pro12Ala substitution in peroxisome proliferator-activated receptor gamma 2 is associated with low adiponectin concentrations in young Japanese men.
|
Metabolism
|
2004
|
0.84
|
|
54
|
Cerebral antioxidant enzyme increase associated with learning deficit in type 2 diabetes rats.
|
Brain Res
|
2012
|
0.83
|
|
55
|
Predictive power of home blood pressure and clinic blood pressure in hypertensive patients with impaired glucose metabolism and diabetes.
|
J Hypertens
|
2013
|
0.83
|
|
56
|
Diabetes insipidus and lymphocytic hypophysitis.
|
Intern Med
|
2003
|
0.83
|
|
57
|
Cryptochrome and Period Proteins Are Regulated by the CLOCK/BMAL1 Gene: Crosstalk between the PPARs/RXRalpha-Regulated and CLOCK/BMAL1-Regulated Systems.
|
PPAR Res
|
2008
|
0.82
|
|
58
|
A possible role of lysophospholipids produced by calcium-independent phospholipase A(2) in membrane-raft budding and fission.
|
Biochim Biophys Acta
|
2009
|
0.82
|
|
59
|
Detection of low titre TBII in patients with Graves' disease using recombinant human TSH receptor.
|
Clin Endocrinol (Oxf)
|
2002
|
0.81
|
|
60
|
Role of lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration.
|
Am J Physiol Gastrointest Liver Physiol
|
2009
|
0.81
|
|
61
|
Acarbose ameliorates atherogenecity of low-density lipoprotein in patients with impaired glucose tolerance.
|
Metabolism
|
2006
|
0.81
|
|
62
|
Involvement of low adiponectin levels in impaired glucose tolerance.
|
Metabolism
|
2008
|
0.81
|
|
63
|
Adiponectin upregulates ferritin heavy chain in skeletal muscle cells.
|
Diabetes
|
2008
|
0.81
|
|
64
|
Effect of p53 deficiency on external vascular cuff-induced neointima formation.
|
Circ J
|
2003
|
0.80
|
|
65
|
Involvement of intestinal alkaline phosphatase in serum apolipoprotein B-48 level and its association with ABO and secretor blood group types.
|
Biochem Biophys Res Commun
|
2006
|
0.80
|
|
66
|
Acarbose improves fibrinolytic activity in patients with impaired glucose tolerance.
|
Metabolism
|
2006
|
0.80
|
|
67
|
Effects of telmisartan on insulin resistance in Japanese type 2 diabetic patients.
|
Intern Med
|
2010
|
0.79
|
|
68
|
Interaction between 3' untranslated region of calcitonin receptor messenger ribonucleic acid (RNA) and adenylate/uridylate (AU)-rich element binding proteins (AU-rich RNA-binding factor 1 and Hu antigen R).
|
Endocrinology
|
2004
|
0.79
|
|
69
|
The paired-box homeodomain transcription factor Pax6 binds to the upstream region of the TRAP gene promoter and suppresses receptor activator of NF-κB ligand (RANKL)-induced osteoclast differentiation.
|
J Biol Chem
|
2013
|
0.79
|
|
70
|
Diabetic retinopathy and microalbuminuria can predict macroalbuminuria and renal function decline in Japanese type 2 diabetic patients: Japan Diabetes Complications Study.
|
Diabetes Care
|
2013
|
0.79
|
|
71
|
[Revised criteria for the early diagnosis of diabetic nephropathy].
|
Nihon Jinzo Gakkai Shi
|
2005
|
0.79
|
|
72
|
Apoptosis of endothelial cells may be mediated by genes of peroxisome proliferator-activated receptor gamma 1 (PPARgamma 1) and PPARalpha genes.
|
J Atheroscler Thromb
|
2003
|
0.79
|
|
73
|
Antioxidant treatment with alpha-tocopherol improves erectile function in hypertensive rats.
|
Hypertens Res
|
2008
|
0.79
|
|
74
|
SH3 domain of the phosphatidylinositol 3-kinase regulatory subunit is responsible for the formation of a sequestration complex with insulin receptor substrate-1.
|
Biochem Biophys Res Commun
|
2007
|
0.79
|
|
75
|
Prevention of microalbuminuria in patients with type 2 diabetes and hypertension.
|
J Hypertens
|
2012
|
0.78
|
|
76
|
Activating effect of momordin, extract of bitter melon (Momordica Charantia L.), on the promoter of human PPARdelta.
|
J Atheroscler Thromb
|
2009
|
0.78
|
|
77
|
Identification of a novel WFS1 mutation (AFF344-345ins) in Japanese patients with Wolfram syndrome.
|
Diabetes Res Clin Pract
|
2005
|
0.78
|
|
78
|
Characterization of the epitopes specific for the monoclonal antibody 9F5-3a and quantification of oxidized HDL in human plasma.
|
Ann Clin Biochem
|
2004
|
0.78
|
|
79
|
A low-frequency GLIS3 variant associated with resistance to Japanese type 1 diabetes.
|
Biochem Biophys Res Commun
|
2013
|
0.78
|
|
80
|
Glycated high-density lipoprotein regulates reactive oxygen species and reactive nitrogen species in endothelial cells.
|
Metabolism
|
2003
|
0.78
|
|
81
|
Glimepiride enhances intrinsic peroxisome proliferator-activated receptor-gamma activity in 3T3-L1 adipocytes.
|
Biochem Biophys Res Commun
|
2005
|
0.78
|
|
82
|
Acarbose attenuates postprandial hyperlipidemia: investigation in an intestinal absorptive cell model.
|
Metabolism
|
2009
|
0.77
|
|
83
|
Correction: A Genome-Wide Association Study for Diabetic Retinopathy in a Japanese Population: Potential Association with a Long Intergenic Non-Coding RNA.
|
PLoS One
|
2015
|
0.77
|
|
84
|
Direct and simple fluorescence detection method for oxidized lipoproteins.
|
Anal Chem
|
2010
|
0.77
|
|
85
|
Statins Activate Human PPARalpha Promoter and Increase PPARalpha mRNA Expression and Activation in HepG2 Cells.
|
PPAR Res
|
2008
|
0.77
|
|
86
|
Proposed reference material for human free immunoglobulin light chain measurement.
|
J Immunoassay Immunochem
|
2006
|
0.77
|
|
87
|
Preferable effects of olmesartan/calcium channel blocker to olmesartan/diuretic on blood pressure variability in very elderly hypertension: COLM study subanalysis.
|
J Hypertens
|
2015
|
0.77
|
|
88
|
Carbon monoxide regulates blood pressure cooperatively with nitric oxide in hypertensive rats.
|
Heart Vessels
|
2002
|
0.77
|
|
89
|
[Prevalence and incidence of diabetic microangiopathy in Japan].
|
Nihon Rinsho
|
2005
|
0.76
|
|
90
|
Treatment with glimepiride, but not mitiglinide and short-acting insulin, resists body weight and abdominal fat reduction under dietary energy restriction.
|
J Atheroscler Thromb
|
2009
|
0.76
|
|
91
|
A Novel Splicing Variant of Peroxisome Proliferator-Activated Receptor-γ (Pparγ1sv) Cooperatively Regulates Adipocyte Differentiation with Pparγ2.
|
PLoS One
|
2013
|
0.76
|
|
92
|
Dopamine D1-like receptor antagonist, SCH23390, exhibits a preventive effect on diabetes mellitus that occurs naturally in NOD mice.
|
Biochem Biophys Res Commun
|
2009
|
0.75
|
|
93
|
Effect of cilnidipine on insulin sensitivity in patients with essential hypertension.
|
Hypertens Res
|
2003
|
0.75
|
|
94
|
Feminizing Adrenocortical Carcinoma with Distinct Histopathological Findings.
|
Intern Med
|
2016
|
0.75
|
|
95
|
Influence of Treatment with Extracts of Hypsyzigus marmoreus Mushroom on Body Composition during Obesity Development in KK-A(y) Mice.
|
J Nutr Sci Vitaminol (Tokyo)
|
2015
|
0.75
|
|
96
|
[Proper use of the dietary supplement (food with health claims) and the formula diet for metabolic syndrome patients].
|
Nihon Rinsho
|
2011
|
0.75
|
|
97
|
[Total care for patients with metabolic syndrome].
|
Nihon Rinsho
|
2004
|
0.75
|
|
98
|
[Series: Clinical study from Japan and its reflections; diabetic retinopathy and microalbuminuria can predict macroalbuminuria and renal function decline in Japanese type 2 diabetic patients: Japan Diabetes Complications Study (JDCS)].
|
Nihon Naika Gakkai Zasshi
|
2014
|
0.75
|
|
99
|
A patient with severe hypertriglyceridemia associated with anemia and hypoalbuminemia.
|
J Atheroscler Thromb
|
2003
|
0.75
|
|
100
|
[Destructive thyroiditis with elevated thyroid stimulation blocking antibody].
|
Nihon Naika Gakkai Zasshi
|
2003
|
0.75
|
|
101
|
[Japan Diabetes Complications Study (JDCS)].
|
Nihon Rinsho
|
2012
|
0.75
|
|
102
|
Geometrical separation method for lipoproteins using bioformulated-fiber matrix electrophoresis: size of high-density lipoprotein does not reflect its density.
|
Anal Chem
|
2010
|
0.75
|
|
103
|
[Adiponectin receptor regulation in diabetic states].
|
Nihon Rinsho
|
2007
|
0.75
|
|
104
|
Tumor-induced osteomalacia: benign tumor recurrence after two surgical resections at two different medical institutions.
|
Endocr Pract
|
2013
|
0.75
|
|
105
|
Treatment with hypotensive agents affects the impaired relaxation of the penile corpus cavernosum in hypertensive rats.
|
Hypertens Res
|
2006
|
0.75
|
|
106
|
[Recent trends in diabetic complications in Japan].
|
Nihon Naika Gakkai Zasshi
|
2004
|
0.75
|
|
107
|
Guidelines for treatment of hypertension in the elderly--2002 revised version.
|
Hypertens Res
|
2003
|
0.75
|
|
108
|
Hypoglycemic effects of colestimide on type 2 diabetic patients with obesity.
|
Endocr J
|
2012
|
0.75
|
|
109
|
Rapid and simple profiling of lipoproteins by polyacrylamide-gel disc electrophoresis to determine the heterogeneity of low-density lipoproteins (LDLs) including small, dense LDL.
|
Recent Pat Cardiovasc Drug Discov
|
2009
|
0.75
|
|
110
|
The possible therapeutic actions of peroxisome proliferator-activated receptor alpha (PPAR alpha) agonists, PPAR gamma agonists, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, angiotensin converting enzyme (ACE) inhibitors and calcium (Ca)-antagonists on vascular endothelial cells.
|
Curr Drug Targets Cardiovasc Haematol Disord
|
2004
|
0.75
|
|
111
|
[Osteoporosis and intake of carbohydrates].
|
Clin Calcium
|
2005
|
0.75
|
|
112
|
[A study about normal values of urinary type IV collagen concentration--aim at constructing a diagnostic guideline for diabetic nephropathy].
|
Nihon Jinzo Gakkai Shi
|
2002
|
0.75
|
|
113
|
Retrospective, observation study: Quantitative and qualitative effect of ezetimibe and HMG-CoA reductase inhibitors on LDL-cholesterol: are there disappearance thresholds for small, dense LDL and IDL?
|
Recent Pat Cardiovasc Drug Discov
|
2010
|
0.75
|