Jennifer Nichols

Author PubWeight™ 147.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003 20.16
2 The ground state of embryonic stem cell self-renewal. Nature 2008 19.44
3 BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 2003 13.47
4 Nanog safeguards pluripotency and mediates germline development. Nature 2007 13.01
5 Promotion of reprogramming to ground state pluripotency by signal inhibition. PLoS Biol 2008 8.55
6 Nanog is the gateway to the pluripotent ground state. Cell 2009 7.27
7 Changing potency by spontaneous fusion. Nature 2002 6.46
8 The transcriptional and epigenomic foundations of ground state pluripotency. Cell 2012 5.87
9 The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nat Cell Biol 2006 5.74
10 Klf4 reverts developmentally programmed restriction of ground state pluripotency. Development 2009 5.49
11 Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells. PLoS Biol 2009 4.60
12 Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal. Cell Stem Cell 2009 3.27
13 Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3. Cell 2013 3.15
14 Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development 2007 2.23
15 Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state. Development 2010 1.58
16 A conserved Oct4/POUV-dependent network links adhesion and migration to progenitor maintenance. Curr Biol 2013 1.54
17 The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate. PLoS Genet 2011 1.48
18 Human hypoblast formation is not dependent on FGF signalling. Dev Biol 2011 1.46
19 A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages. Nat Cell Biol 2013 1.45
20 Parameters influencing derivation of embryonic stem cells from murine embryos. Genesis 2008 1.43
21 Totipotent embryonic stem cells arise in ground-state culture conditions. Cell Rep 2013 1.43
22 SoxB transcription factors specify neuroectodermal lineage choice in ES cells. Mol Cell Neurosci 2004 1.38
23 Differential plasticity of epiblast and primitive endoderm precursors within the ICM of the early mouse embryo. Development 2011 1.33
24 LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease. Nat Cell Biol 2010 1.25
25 Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility. Proc Natl Acad Sci U S A 2002 1.21
26 Rebuilding pluripotency from primordial germ cells. Stem Cell Reports 2013 1.09
27 Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos. Development 2010 1.07
28 The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis. Nat Cell Biol 2011 1.07
29 Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development 2014 1.05
30 The germ cell determinant Blimp1 is not required for derivation of pluripotent stem cells. Cell Stem Cell 2012 0.97
31 The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3. Genes Dev 2012 0.95
32 A practical and efficient cellular substrate for the generation of induced pluripotent stem cells from adults: blood-derived endothelial progenitor cells. Stem Cells Transl Med 2012 0.95
33 Randomized controlled comparison of cosmetic outcomes of simple facial lacerations closed with Steri Strip Skin Closures or Dermabond tissue adhesive. Pediatr Emerg Care 2004 0.92
34 Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations. J R Soc Interface 2012 0.91
35 A molecular basis for developmental plasticity in early mammalian embryos. Development 2013 0.89
36 The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD mice. PLoS One 2013 0.87
37 Eomesodermin is expressed in mouse oocytes and pre-implantation embryos. Mol Reprod Dev 2005 0.86
38 Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells. Mech Dev 2008 0.84
39 Nanog retrotransposed genes with functionally conserved open reading frames. Mamm Genome 2006 0.81
40 Acute loss of Cited2 impairs Nanog expression and decreases self-renewal of mouse embryonic stem cells. Stem Cells 2015 0.79
41 Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm. Dev Dyn 2003 0.79
42 Randomized trial of harp therapy during in vitro fertilization-embryo transfer. J Evid Based Complementary Altern Med 2013 0.77
43 The KRAB domain zinc finger protein, Zfp157, is expressed in multiple tissues during mouse embryogenesis and in specific cells in adult mammary gland and skin. Genesis 2013 0.76
44 Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human. Cell 2015 0.75
45 Derivation of Mouse Embryonic Stem (ES) Cell Lines Using Small-Molecule Inhibitors of Erk and Gsk3 Signaling (2i). Cold Spring Harb Protoc 2017 0.75
46 Transgenic systems in nuclear reprogramming. Methods Mol Biol 2006 0.75