Published in PeerJ on February 12, 2013
Catalysis of Na+ permeation in the bacterial sodium channel Na(V)Ab. Proc Natl Acad Sci U S A (2013) 1.09
K(+) and Na(+) conduction in selective and nonselective ion channels via molecular dynamics simulations. Biophys J (2013) 0.87
The mechanism of Na⁺/K⁺ selectivity in mammalian voltage-gated sodium channels based on molecular dynamics simulation. Biophys J (2013) 0.87
Locating the route of entry and binding sites of benzocaine and phenytoin in a bacterial voltage gated sodium channel. PLoS Comput Biol (2014) 0.81
Effects of the protonation state of the EEEE motif of a bacterial Na(+)-channel on conduction and pore structure. Biophys J (2014) 0.80
Different inward and outward conduction mechanisms in NaVMs suggested by molecular dynamics simulations. PLoS Comput Biol (2014) 0.78
Detailed Examination of a Single Conduction Event in a Potassium Channel. J Phys Chem Lett (2013) 0.75
K+ Block Is the Mechanism of Functional Asymmetry in Bacterial Nav Channels. PLoS Comput Biol (2016) 0.75
Scalable molecular dynamics with NAMD. J Comput Chem (2005) 59.49
All-atom empirical potential for molecular modeling and dynamics studies of proteins. J Phys Chem B (1998) 54.00
Ionic blockage of sodium channels in nerve. J Gen Physiol (1973) 20.47
Mechanism of ion permeation through calcium channels. Nature (1984) 9.82
From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron (2000) 9.51
Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types. J Phys Chem B (2010) 8.70
The crystal structure of a voltage-gated sodium channel. Nature (2011) 7.82
Calcium channel characteristics conferred on the sodium channel by single mutations. Nature (1992) 4.90
Determination of alkali and halide monovalent ion parameters for use in explicitly solvated biomolecular simulations. J Phys Chem B (2008) 4.68
A prokaryotic voltage-gated sodium channel. Science (2001) 4.56
Resurgence of sodium channel research. Annu Rev Physiol (2001) 4.11
Ca2+ channel selectivity at a single locus for high-affinity Ca2+ interactions. Neuron (1995) 3.39
Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel. Nature (2012) 2.97
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states. Nature (2012) 2.78
Voltage-dependent calcium block of normal and tetramethrin-modified single sodium channels. Biophys J (1984) 2.60
The Ca channel in skeletal muscle is a large pore. Proc Natl Acad Sci U S A (1985) 2.49
Two identical noninteracting sites in an ion channel revealed by proton transfer. Science (1994) 2.44
On the structural basis for ionic selectivity among Na+, K+, and Ca2+ in the voltage-gated sodium channel. Biophys J (1996) 2.39
Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing. Nat Commun (2012) 2.01
The cation selectivity filter of the bacterial sodium channel, NaChBac. J Gen Physiol (2002) 1.94
Mechanisms of permeation and selectivity in calcium channels. Biophys J (2001) 1.79
The allosteric role of the Ca2+ switch in adhesion and elasticity of C-cadherin. Biophys J (2008) 1.72
Divalent cation selectivity for external block of voltage-dependent Na+ channels prolonged by batrachotoxin. Zn2+ induces discrete substates in cardiac Na+ channels. J Gen Physiol (1991) 1.66
The predominant role of coordination number in potassium channel selectivity. Biophys J (2007) 1.62
On the structural basis for size-selective permeation of organic cations through the voltage-gated sodium channel. Effect of alanine mutations at the DEKA locus on selectivity, inhibition by Ca2+ and H+, and molecular sieving. J Gen Physiol (1997) 1.59
Binding and selectivity in L-type calcium channels: a mean spherical approximation. Biophys J (2000) 1.53
Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction. Nature (2012) 1.41
Energetics of divalent selectivity in a calcium channel: the ryanodine receptor case study. Biophys J (2007) 1.39
Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins. Proc Natl Acad Sci U S A (2011) 1.23
Mechanism of ion permeation and selectivity in a voltage gated sodium channel. J Am Chem Soc (2012) 1.17
Ionic selectivity in L-type calcium channels by electrostatics and hard-core repulsion. J Gen Physiol (2009) 1.15
On conduction in a bacterial sodium channel. PLoS Comput Biol (2012) 1.14
Electrostatic basis of valence selectivity in cationic channels. Biochim Biophys Acta (2005) 1.14
Molecular dynamics study of calbindin D9k in the apo and singly and doubly calcium-loaded states. Proteins (1998) 1.10
Ion permeation, divalent ion block, and chemical modification of single sodium channels. Description by single- and double-occupancy rate-theory models. J Gen Physiol (1994) 1.06
Mechanisms of valence selectivity in biological ion channels. Cell Mol Life Sci (2006) 1.05
Molecular localization of regions in the L-type calcium channel critical for dihydropyridine action. Neuron (1993) 1.04
The EEEE locus is the sole high-affinity Ca(2+) binding structure in the pore of a voltage-gated Ca(2+) channel: block by ca(2+) entering from the intracellular pore entrance. J Gen Physiol (2000) 0.98
Intrinsic ion selectivity of narrow hydrophobic pores. J Phys Chem B (2009) 0.98
Molecular mechanisms of calcium and magnesium binding to parvalbumin. Biophys J (2002) 0.96
Polarization of water in the first hydration shell of K+ and Ca2+ ions. J Phys Chem B (2008) 0.88
A model of sodium channels. Biochim Biophys Acta (2005) 0.84
A model of calcium channels. Biochim Biophys Acta (2000) 0.84