Published in Br J Pharmacol on July 01, 2013
Cytokine-induced loss of glucocorticoid function: effect of kinase inhibitors, long-acting β(2)-adrenoceptor [corrected] agonist and glucocorticoid receptor ligands. PLoS One (2015) 1.41
An analysis of glucocorticoid receptor-mediated gene expression in BEAS-2B human airway epithelial cells identifies distinct, ligand-directed, transcription profiles with implications for asthma therapeutics. Br J Pharmacol (2015) 0.83
Effects of representative glucocorticoids on TNFα- and CD40L-induced NF-κB activation in sensor cells. Steroids (2014) 0.77
Understanding how long-acting β2 -adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids in asthma - an update. Br J Pharmacol (2016) 0.77
The long-acting β2 -adrenoceptor agonist, indacaterol, enhances glucocorticoid receptor-mediated transcription in human airway epithelial cells in a gene- and agonist-dependent manner. Br J Pharmacol (2015) 0.77
Glucocorticoid therapy and ocular hypertension. Eur J Pharmacol (2016) 0.75
The transrepression arm of glucocorticoid receptor signaling is protective in mutant huntingtin-mediated neurodegeneration. Cell Death Differ (2015) 0.75
Animal research: reporting in vivo experiments: the ARRIVE guidelines. Br J Pharmacol (2010) 17.30
Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol (2010) 13.76
Mechanisms involved in the side effects of glucocorticoids. Pharmacol Ther (2002) 5.43
Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clin Sci (Lond) (1998) 4.31
Multiple actions of steroid hormones--a focus on rapid, nongenomic effects. Pharmacol Rev (2000) 2.94
Anti-inflammatory actions of steroids: molecular mechanisms. Trends Pharmacol Sci (1993) 2.86
Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease. Am J Physiol Lung Cell Mol Physiol (2007) 1.58
Cross-talk between glucocorticoid receptor and AP-1. Oncogene (2001) 1.54
Maps and legends: the quest for dissociated ligands of the glucocorticoid receptor. Pharmacol Ther (2011) 1.50
Selective glucocorticoid receptor agonists (SEGRAs): novel ligands with an improved therapeutic index. Mol Cell Endocrinol (2007) 1.39
Molecular mechanisms of anti-inflammatory action of glucocorticoids. Bioessays (1996) 1.36
X-ray crystal structure of the novel enhanced-affinity glucocorticoid agonist fluticasone furoate in the glucocorticoid receptor-ligand binding domain. J Med Chem (2008) 1.36
A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance. J Immunol (2002) 1.13
Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity. J Immunol (2001) 1.12
Safety of inhaled and intranasal corticosteroids: lessons for the new millennium. Drug Saf (2000) 1.10
Mechanisms of Glucocorticoid-receptor-mediated Repression of Gene Expression. Trends Endocrinol Metab (1999) 1.10
Molecular genetic analysis of glucocorticoid signaling using the Cre/loxP system. Biol Chem (2001) 1.09
Role of dual specificity phosphatases in biological responses to glucocorticoids. J Biol Chem (2008) 1.08
Characterization of ZK 245186, a novel, selective glucocorticoid receptor agonist for the topical treatment of inflammatory skin diseases. Br J Pharmacol (2009) 1.05
Inhaled corticosteroids: past lessons and future issues. J Allergy Clin Immunol (2003) 1.02
Dissociated glucocorticoids with anti-inflammatory potential repress interleukin-6 gene expression by a nuclear factor-kappaB-dependent mechanism. Mol Pharmacol (1999) 0.99
Glucocorticoid-induced osteoporosis. Baillieres Best Pract Res Clin Endocrinol Metab (2000) 0.99
A review of the pharmacology and pharmacokinetics of inhaled fluticasone propionate and mometasone furoate. Clin Ther (2001) 0.97
Cigarette smoke extract induced cytokine and chemokine gene expression changes in COPD macrophages. Cytokine (2008) 0.95
Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1. Br J Pharmacol (2012) 0.91
Physical interaction and functional synergy between glucocorticoid receptor and Ets2 proteins for transcription activation of the rat cytochrome P-450c27 promoter. J Biol Chem (2001) 0.90
Corticosteroids--from an idea to clinical use. Best Pract Res Clin Rheumatol (2004) 0.90
New Glucocorticosteroids with an improved therapeutic ratio? Pulm Pharmacol Ther (2001) 0.90
Molecular genetic dissection of glucocorticoid receptor function in vivo. Z Rheumatol (2000) 0.89
Mometasone furoate is a less specific glucocorticoid than fluticasone propionate. Eur Respir J (2002) 0.88
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor. Proc Natl Acad Sci U S A (2009) 0.86
Glucocorticoid-induced osteoporosis: pathogenesis, diagnosis, and management. Prev Med (2003) 0.85
Genetic dissection of corticosteroid receptor function in mice. Horm Metab Res (2004) 0.85
Dissociated non-steroidal glucocorticoids: tuning out untoward effects. Expert Opin Ther Pat (2007) 0.83
Combined fluticasone furoate/vilanterol reduces decline in lung function following inhaled allergen 23 h after dosing in adult asthma: a randomised, controlled trial. Clin Transl Allergy (2012) 0.83
Anti-inflammation: direct physical association and functional antagonism between transcription factor NF-KB and the glucocorticoid receptor. Chest (1995) 0.83
Glucocorticoid-induced osteoporosis: pathophysiological data and recent treatments. Joint Bone Spine (2003) 0.82
Treatment of inflammatory bowel disease with corticosteroids. Gastroenterol Clin North Am (2004) 0.82
A pharmacological approach to enhancing the therapeutic index of corticosteroids in airway inflammatory disease. Curr Opin Pharmacol (2005) 0.82
Molecular basis for corticosteroid action in asthma. Chem Immunol (2000) 0.81
Nuclear receptors: doubling up in the lung. Curr Opin Pharmacol (2008) 0.78
Designing corticosteroid drugs for pulmonary selectivity. Proc Am Thorac Soc (2004) 0.78
Corticosteroid therapy for rheumatoid arthritis. Med Clin North Am (1973) 0.77
Ciclesonide: a novel inhaled corticosteroid. Expert Opin Investig Drugs (2004) 0.77
Benefits of low-dose corticosteroids in rheumatoid arthritis. Bull Rheum Dis (1997) 0.77
Corticosteroids in the treatment of rheumatologic diseases. Curr Opin Rheumatol (1996) 0.76
Norfloxacin and the antibacterial gamma pyridone beta carboxylic acids. J Antimicrob Chemother (1982) 12.18
Effect of chain length and unsaturation on elasticity of lipid bilayers. Biophys J (2000) 8.35
Mesenteric and retroperitoneal cysts. Ann Surg (1986) 3.99
Factors affecting time delay to treatment in a tuberculosis control programme in a sub-Saharan African country: the experience of The Gambia. Int J Tuberc Lung Dis (2001) 3.75
Water permeability and mechanical strength of polyunsaturated lipid bilayers. Biophys J (2000) 3.16
Tension-stabilized pores in giant vesicles: determination of pore size and pore line tension. Biochim Biophys Acta (1993) 3.00
The effects of bilayer thickness and tension on gramicidin single-channel lifetime. Biochim Biophys Acta (1983) 2.97
Prospective study of chlamydial infection in neonates. Lancet (1979) 2.80
Ancillary-written prescription errors. J R Coll Gen Pract (1980) 2.77
Correlation of the highest-energy cosmic rays with nearby extragalactic objects. Science (2007) 2.57
Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol). Biophys J (1995) 2.35
A regular pattern of two types of 100-residue motif in the sequence of titin. Nature (1990) 2.29
Evolving a lingua franca and associated software infrastructure for computational systems biology: the Systems Biology Markup Language (SBML) project. Syst Biol (Stevenage) (2004) 2.21
Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release. Cancer Res (2000) 2.17
A microbiological survey of automated biochemical machines. J Clin Pathol (1980) 2.17
A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor. J Virol (1999) 2.12
Volume and osmotic properties of human neutrophils. Blood (1993) 2.08
Prospective study of perinatal transmission of Chlamydia trachomatis. JAMA (1986) 2.06
Giant vesicle bilayers composed of mixtures of lipids, cholesterol and polypeptides. Thermomechanical and (mutual) adherence properties. Faraday Discuss Chem Soc (1986) 2.06
Time-dependent recovery of passive neutrophils after large deformation. Biophys J (1991) 2.00
Structure and cohesive properties of sphingomyelin/cholesterol bilayers. Biochemistry (1992) 1.95
Focus groups reveal perils and promises of managed care for nurse practitioners. Nurse Pract (1998) 1.93
A death-domain-containing receptor that mediates apoptosis. Nature (1996) 1.92
NF-kappaB activation is a critical regulator of human granulocyte apoptosis in vitro. J Biol Chem (1999) 1.89
A randomized, double-blind, placebo-controlled study of sumatriptan nasal spray in the treatment of acute migraine in adolescents. Pediatrics (2000) 1.89
Randomized trial of coordinated psychosocial interventions based on patient self-assessments versus standard care to improve the psychosocial functioning of patients with cancer. J Clin Oncol (2001) 1.84
Cl- secretion in a model intestinal epithelium induced by a neutrophil-derived secretagogue. J Clin Invest (1992) 1.81
Epidemiologic and clinical features of patients infected with Shigella who attended a diarrheal disease hospital in Bangladesh. J Infect Dis (1982) 1.79
Experimental tests for protrusion and undulation pressures in phospholipid bilayers. Biochemistry (1995) 1.78
Role of the membrane cortex in neutrophil deformation in small pipets. Biophys J (1994) 1.78
Biomembrane templates for nanoscale conduits and networks. Science (1996) 1.73
Prescriptions written by ancillary staff. J R Coll Gen Pract (1976) 1.72
Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions. Proc Natl Acad Sci U S A (1999) 1.69
Satisfaction with the decision to participate in cancer clinical trials is high, but understanding is a problem. Support Care Cancer (2010) 1.69
Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue. Cancer Res (1993) 1.69
A synthetic mimic of the secretory granule for drug delivery. Nature (1998) 1.64
Viscosity of passive human neutrophils undergoing small deformations. Biophys J (1993) 1.61
Gabapentin as a potential treatment for anxiety disorders. Am J Psychiatry (1998) 1.61
National hand hygiene campaigns in Europe, 2000-2009. Euro Surveill (2009) 1.58
Lifetime suicide rates in treated schizophrenia: 1875-1924 and 1994-1998 cohorts compared. Br J Psychiatry (2006) 1.58
Effects of the cyclin-dependent kinase inhibitor R-roscovitine on eosinophil survival and clearance. Clin Exp Allergy (2011) 1.53
Interdisciplinary health professional education: a historical review. Adv Health Sci Educ Theory Pract (2001) 1.50
Reduction in QT dispersion by sotalol following myocardial infarction. Eur Heart J (1991) 1.50
In utero lead exposure. MCN Am J Matern Child Nurs (1990) 1.50
Stabilization of F-actin prevents cAMP-elicited Cl- secretion in T84 cells. J Clin Invest (1991) 1.49
Cholecystokinin elicits the complete behavioral sequence of satiety in rats. J Comp Physiol Psychol (1975) 1.49
Measurement of the depth of maximum of extensive air showers above 10{18} eV. Phys Rev Lett (2010) 1.48
Patterns of survival in patients with recurrent follicular lymphoma: a 20-year study from a single center. J Clin Oncol (1995) 1.48
High-dose therapy with autologous haematopoietic support in patients with transformed follicular lymphoma: a study of 27 patients from a single centre. Ann Oncol (1998) 1.48
Validation of International Society of Urological Pathology (ISUP) grading for prostatic adenocarcinoma in thin core biopsies using TROG 03.04 'RADAR' trial clinical data. Pathology (2015) 1.47
Interbilayer interactions between sphingomyelin and sphingomyelin/cholesterol bilayers. Biochemistry (1992) 1.45
A volumetric study of measurements and calculations of lung density corrections for 6 and 18 MV photons. Int J Radiat Oncol Biol Phys (1997) 1.44
DR3 regulates negative selection during thymocyte development. Mol Cell Biol (2001) 1.44
Therapy-related myelodysplasia and secondary acute myelogenous leukemia after high-dose therapy with autologous hematopoietic progenitor-cell support for lymphoid malignancies. J Clin Oncol (2000) 1.43
Regional scale impacts of distinct CO(2) additions in the North Sea. Mar Pollut Bull (2008) 1.41
Infection with Chlamydia trachomatis: involvement of multiple anatomic sites in neonates. J Infect Dis (1979) 1.41
Longer survival with higher doses of thoracic radiotherapy in patients with limited non-small cell lung cancer. Int J Radiat Oncol Biol Phys (1993) 1.40
Medical therapy of Mycobacterium avium-intracellulare pulmonary disease. Am Rev Respir Dis (1986) 1.40
[Neonatal respiratory distress syndrome treated with a natural surfactant. The Norwegian Curosurf study]. Tidsskr Nor Laegeforen (1993) 1.40
Salvage radiotherapy for Hodgkin's disease following chemotherapy failure. Int J Radiat Oncol Biol Phys (1997) 1.38
EZH2 Y641 mutations in follicular lymphoma. Leukemia (2011) 1.37
Use of diagnostic markers to monitor fasciolosis and gastrointestinal nematodes on an organic dairy farm. Vet Rec (2011) 1.37
Tensions and free energies of formation of "solventless" lipid bilayers. Measurement of high contact angles. Biophys J (1983) 1.32
AnkB, a periplasmic ankyrin-like protein in Pseudomonas aeruginosa, is required for optimal catalase B (KatB) activity and resistance to hydrogen peroxide. J Bacteriol (2000) 1.31
The application of computer touch-screen technology in screening for psychosocial distress in an ambulatory oncology setting. Eur J Cancer Care (Engl) (2002) 1.26
Aerosols in the mortuary. J Clin Pathol (1983) 1.26
Scedosporium prolificans, a multi-resistant fungus, from a U.K. AIDS patient. J Infect (1995) 1.23
Avidin-biotin interactions at vesicle surfaces: adsorption and binding, cross-bridge formation, and lateral interactions. Biophys J (1996) 1.23
Drinking water quality and health-care utilization for gastrointestinal illness in greater Vancouver. Can Commun Dis Rep (2000) 1.21
Changing epidemiology of malignant melanoma in Queensland. Med J Aust (1980) 1.19
Homozygous and compound heterozygous mutations at the Werner syndrome locus. Hum Mol Genet (1996) 1.19
Mechanism of the tumor necrosis factor alpha-mediated induction of endothelial tissue factor. J Biol Chem (1995) 1.18
Adenocarcinoma of the nose and paranasal sinuses in woodworkers in the state of Victoria, Australia. Cancer (1975) 1.18
Differential immunolocalization of VEGF in rat and human adult lung, and in experimental rat lung fibrosis: light, fluorescence, and electron microscopy. Anat Rec (1999) 1.17
Genome-wide detection of recurring sites of uniparental disomy in follicular and transformed follicular lymphoma. Leukemia (2007) 1.17
Tuberculosis. Cause of death in antibiotic era. Chest (1985) 1.16
Synovial hemangioma: imaging features in eight histologically proven cases, review of the literature, and differential diagnosis. Skeletal Radiol (1995) 1.16
Modulation of the interbilayer hydration pressure by the addition of dipoles at the hydrocarbon/water interface. Biophys J (1992) 1.15
Determinants of the geographical distribution of endemic giardiasis in Ontario, Canada: a spatial modelling approach. Epidemiol Infect (2004) 1.15
The Ethiopia applied nutrition project. Proc R Soc Lond B Biol Sci (1976) 1.15
Selective depression of motion sensitivity during saccades. J Physiol (1982) 1.15
The mobilization of free fatty acids from rabbit adipose tissue in situ. Br J Pharmacol (1968) 1.14
Expression of the extracellular matrix signaling molecule Cyr61 is downregulated in prostate cancer. Prostate (1998) 1.14
Hyperthermia increases accumulation of technetium-99m-labeled liposomes in feline sarcomas. Clin Cancer Res (2000) 1.13
Studies of the interaction between titin and myosin. J Cell Biol (1995) 1.13
Quantitative nanoscale imaging of lattice distortions in epitaxial semiconductor heterostructures using nanofocused X-ray Bragg projection ptychography. Nano Lett (2012) 1.12
The relationship between functional vasodilatation in adipose tissue and prostaglandin. Br J Pharmacol (1970) 1.12
Measurement of material extravasation in microvascular networks using fluorescence video-microscopy. Microvasc Res (1993) 1.12
Mantle cell lymphoma: natural history defined in a serially biopsied population over a 20-year period. Ann Oncol (1995) 1.12
The Xenopus oocyte as a surrogate secretory system. The specificity of protein export. Eur J Biochem (1980) 1.11
The viscosity of neutrophils and their transit times through small pores. Biorheology (1990) 1.11
Studies of the pH gradient and thickness of frog gastric mucus gel. Gastroenterology (1983) 1.10
Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases. J Biol Chem (2001) 1.09
Effect of pentoxifylline on the flow of polymorphonuclear leukocytes through a model capillary. Angiology (1990) 1.07
Are dependency and self-criticism risk factors for major depressive disorder? Can J Psychiatry (1997) 1.07
Acute myeloblastic leukaemia in AIDS. AIDS (1990) 1.07
The effect of nanocrystal surface structure on the luminescence properties: photoemission study of HF-etched InP nanocrystals. J Chem Phys (2005) 1.07
Hippocampal pyramidal cell disarray in schizophrenia as a bilateral phenomenon. Arch Gen Psychiatry (1991) 1.06
Near-field scanner for moving molecules. Phys Rev Lett (2001) 1.06