PubRank

Patricia J Keely

Author PubWeight™ 75.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Collagen reorganization at the tumor-stromal interface facilitates local invasion. BMC Med 2006 6.44
2 Collagen density promotes mammary tumor initiation and progression. BMC Med 2008 5.13
3 ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix. J Cell Biol 2003 4.24
4 Focal adhesion regulation of cell behavior. Biochim Biophys Acta 2004 3.83
5 Aligned collagen is a prognostic signature for survival in human breast carcinoma. Am J Pathol 2011 3.70
6 Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization. Biophys J 2008 3.49
7 Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis. Cell 2011 3.37
8 Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression. Cold Spring Harb Perspect Biol 2011 2.48
9 Metabolic mapping of MCF10A human breast cells via multiphoton fluorescence lifetime imaging of the coenzyme NADH. Cancer Res 2005 2.15
10 Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. Nat Med 2011 2.12
11 In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia. J Biomed Opt 2007 2.09
12 The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis. Nat Cell Biol 2013 1.93
13 Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling. J Cell Sci 2011 1.90
14 Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer. Am J Pathol 2008 1.82
15 Multiphoton microscopy and fluorescence lifetime imaging microscopy (FLIM) to monitor metastasis and the tumor microenvironment. Clin Exp Metastasis 2008 1.51
16 Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension. Mol Biol Cell 2009 1.47
17 Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers. Cell Adh Migr 2012 1.41
18 Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects. Integr Biol (Camb) 2010 1.41
19 Control of 3-dimensional collagen matrix polymerization for reproducible human mammary fibroblast cell culture in microfluidic devices. Biomaterials 2009 1.37
20 Use of three-dimensional collagen gels to study mechanotransduction in T47D breast epithelial cells. Biol Proced Online 2005 1.32
21 R-Ras controls membrane protrusion and cell migration through the spatial regulation of Rac and Rho. Mol Biol Cell 2004 1.28
22 Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'. Biochem J 2002 1.20
23 R-Ras promotes focal adhesion formation through focal adhesion kinase and p130(Cas) by a novel mechanism that differs from integrins. Mol Cell Biol 2003 1.15
24 Stiff collagen matrices increase tumorigenic prolactin signaling in breast cancer cells. J Biol Chem 2013 1.15
25 Microtubules regulate GEF-H1 in response to extracellular matrix stiffness. Mol Biol Cell 2012 1.14
26 Nonlinear optical imaging and spectral-lifetime computational analysis of endogenous and exogenous fluorophores in breast cancer. J Biomed Opt 2008 1.14
27 Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas. J Biol Chem 2006 1.13
28 Fluorescence lifetime imaging of endogenous fluorophores in histopathology sections reveals differences between normal and tumor epithelium in carcinoma in situ of the breast. Cell Biochem Biophys 2009 1.13
29 The role of focal adhesion kinase in tumor initiation and progression. Cell Adh Migr 2009 1.11
30 Autofluorescence spectroscopy of normal and malignant human breast cell lines. Photochem Photobiol 2003 1.09
31 Shining new light on 3D cell motility and the metastatic process. Trends Cell Biol 2009 1.09
32 The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon. J Cell Sci 2006 1.07
33 Nonlinear optical imaging of cellular processes in breast cancer. Microsc Microanal 2008 1.04
34 Structural changes in mixed Col I/Col V collagen gels probed by SHG microscopy: implications for probing stromal alterations in human breast cancer. Biomed Opt Express 2011 1.01
35 R-Ras regulates beta1-integrin trafficking via effects on membrane ruffling and endocytosis. BMC Cell Biol 2010 1.00
36 RhoA biological activity is dependent on prenylation but independent of specific isoprenoid modification. Cell Growth Differ 2002 0.95
37 Breast tumor and stromal cell responses to TGF-β and hypoxia in matrix deposition. Matrix Biol 2012 0.92
38 Engineering three-dimensional collagen matrices to provide contact guidance during 3D cell migration. Curr Protoc Cell Biol 2010 0.90
39 Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progression. Crit Rev Eukaryot Gene Expr 2013 0.90
40 A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys. Aging Cell 2013 0.89
41 RhoA is down-regulated at cell-cell contacts via p190RhoGAP-B in response to tensional homeostasis. Mol Biol Cell 2013 0.87
42 An antiangiogenic neurokinin-B/thromboxane A2 regulatory axis. J Cell Biol 2006 0.86
43 LPS modulates rhinovirus-induced chemokine secretion in monocytes and macrophages. Am J Respir Cell Mol Biol 2014 0.83
44 Nonlinear optical microscopy and computational analysis of intrinsic signatures in breast cancer. Conf Proc IEEE Eng Med Biol Soc 2009 0.82