1
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Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity.
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Blood
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2008
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7.15
|
2
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Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes.
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Cancer Res
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2010
|
4.25
|
3
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Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates.
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Nat Genet
|
2009
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3.86
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4
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Vitamin D: modulator of the immune system.
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Curr Opin Pharmacol
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2010
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3.31
|
5
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Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice.
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J Clin Invest
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2012
|
1.84
|
6
|
Vitamin D and diabetes.
|
Endocrinol Metab Clin North Am
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2010
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1.52
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7
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Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells.
|
J Biol Chem
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2005
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1.50
|
8
|
Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.
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Cancer Res
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2013
|
1.46
|
9
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Regulation of vitamin D homeostasis: implications for the immune system.
|
Nutr Rev
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2008
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1.33
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10
|
Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation.
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J Biol Chem
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2011
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1.20
|
11
|
Vitamin D insufficiency: implications for the immune system.
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Pediatr Nephrol
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2010
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1.18
|
12
|
Human T lymphocytes are direct targets of 1,25-dihydroxyvitamin D3 in the immune system.
|
J Steroid Biochem Mol Biol
|
2010
|
1.18
|
13
|
Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
|
Diabetes
|
2012
|
1.16
|
14
|
Vitamin D signaling in immune-mediated disorders: Evolving insights and therapeutic opportunities.
|
Mol Aspects Med
|
2008
|
1.16
|
15
|
Islet infiltration, cytokine expression and beta cell death in the NOD mouse, BB rat, Komeda rat, LEW.1AR1-iddm rat and humans with type 1 diabetes.
|
Diabetologia
|
2013
|
1.15
|
16
|
Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.
|
Diabetes
|
2008
|
1.14
|
17
|
The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation.
|
J Immunol
|
2010
|
1.12
|
18
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Protective role of IFN-gamma in collagen-induced arthritis conferred by inhibition of mycobacteria-induced granulocyte chemotactic protein-2 production.
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J Leukoc Biol
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2007
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1.09
|
19
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Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved.
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Mol Cell Proteomics
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2007
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1.05
|
20
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1,25-Dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism.
|
Immunobiology
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2012
|
0.98
|
21
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Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system.
|
J Steroid Biochem Mol Biol
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2004
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0.97
|
22
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1,25-Dihydroxyvitamin D3 alters murine dendritic cell behaviour in vitro and in vivo.
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Diabetes Metab Res Rev
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2011
|
0.96
|
23
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Pancreatic duct cells in human islet cell preparations are a source of angiogenic cytokines interleukin-8 and vascular endothelial growth factor.
|
Diabetes
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2008
|
0.94
|
24
|
Extraskeletal effects of vitamin D.
|
Endocrinol Metab Clin North Am
|
2012
|
0.93
|
25
|
Tumor-induced myeloid-derived suppressor cell subsets exert either inhibitory or stimulatory effects on distinct CD8+ T-cell activation events.
|
Eur J Immunol
|
2013
|
0.93
|
26
|
Vitamin D in autoimmune, infectious and allergic diseases: a vital player?
|
Best Pract Res Clin Endocrinol Metab
|
2011
|
0.92
|
27
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Novel insights in the immune function of the vitamin D system: synergism with interferon-beta.
|
J Steroid Biochem Mol Biol
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2006
|
0.91
|
28
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Vitamin D and diabetes: the odd couple.
|
Trends Endocrinol Metab
|
2013
|
0.91
|
29
|
Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection.
|
Proc Natl Acad Sci U S A
|
2014
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0.88
|
30
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Vitamin D and diabetes.
|
Rheum Dis Clin North Am
|
2012
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0.86
|
31
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A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.
|
J Biol Chem
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2014
|
0.82
|
32
|
Calcium insufficiency accelerates type 1 diabetes in vitamin D receptor-deficient nonobese diabetic (NOD) mice.
|
Endocrinology
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2011
|
0.81
|
33
|
Effects of vitamin D on antigen-specific and non-antigen-specific immune modulation: relevance for type 1 diabetes.
|
Pediatr Diabetes
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2012
|
0.81
|
34
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Prospectively isolated NGN3-expressing progenitors from human embryonic stem cells give rise to pancreatic endocrine cells.
|
Stem Cells Transl Med
|
2014
|
0.80
|
35
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Increased beta-cell mass by islet transplantation and PLAG1 overexpression causes hyperinsulinemic normoglycemia and hepatic insulin resistance in mice.
|
Diabetes
|
2010
|
0.78
|
36
|
1,25-Dihydroxyvitamin D3 alters the profile of bone marrow-derived dendritic cells of NOD mice.
|
Ann N Y Acad Sci
|
2004
|
0.77
|
37
|
Quantification of chemokines by real-time reverse transcriptase PCR: applications in type 1 diabetes.
|
Expert Rev Mol Diagn
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2006
|
0.77
|
38
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Antigen-based vs. systemic immunomodulation in type 1 diabetes: the pros and cons.
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Islets
|
2013
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0.76
|
39
|
Late CD8+ T cell-dependent xenoantibody production in innate tolerant nude rats after hamster islet grafting but not after hamster heart grafting.
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Transplantation
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2008
|
0.76
|
40
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Reversal of hyperglycemia by insulin-secreting rat bone marrow- and blastocyst-derived hypoblast stem cell-like cells.
|
PLoS One
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2013
|
0.75
|
41
|
Seasonality of birth in patients with type 1 diabetes.
|
Lancet
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2002
|
0.75
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42
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Vascular Endothelial Growth Factor Up-regulation in Human Amniotic Fluid Stem Cell Enhances Nephroprotection After Ischemia-Reperfusion Injury in the Rat.
|
Crit Care Med
|
2017
|
0.75
|
43
|
Pdx1- and Ngn3-Cre-mediated PLAG1 expression in the pancreas leads to endocrine hormone imbalances that affect glucose metabolism.
|
Cell Transplant
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2011
|
0.75
|
44
|
Clinical Immunosuppressants Inhibit Inflammatory, Proliferative, and Reprogramming Potential, But Not Angiogenesis of Human Pancreatic Duct Cells.
|
Cell Transplant
|
2014
|
0.75
|