Malcolm V Brock

Author PubWeight™ 75.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer. PLoS Med 2006 5.80
2 Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat Genet 2012 4.70
3 Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. Cancer Discov 2011 4.60
4 Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells. Cancer Cell 2012 3.82
5 PIK3CA gene mutations in pediatric and adult glioblastoma multiforme. Mol Cancer Res 2006 3.72
6 Elevated incidence of lung cancer among HIV-infected individuals. J Clin Oncol 2006 2.46
7 Epidemiology of lung cancer: looking to the future. J Clin Oncol 2005 2.33
8 Promoter hypermethylation of resected bronchial margins: a field defect of changes? Clin Cancer Res 2004 1.93
9 Defining a gene promoter methylation signature in sputum for lung cancer risk assessment. Clin Cancer Res 2012 1.80
10 Epidemiology of lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2013 1.77
11 Neoadjuvant chemoradiation therapy is beneficial for clinical stage T2 N0 esophageal cancer patients due to inaccurate preoperative staging. Ann Thorac Surg 2012 1.69
12 The effect of volume on esophageal cancer resections: what constitutes acceptable resection volumes for centers of excellence? J Thorac Cardiovasc Surg 2009 1.55
13 Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer. Cancer Res 2009 1.55
14 Time for oncologists to opt in for routine opt-out HIV testing? JAMA 2010 1.53
15 Molecular assessment of lymph nodes in patients with resected stage I non-small cell lung cancer: preliminary results of a prospective study. J Thorac Cardiovasc Surg 2002 1.46
16 Hypermethylation of the GATA genes in lung cancer. Clin Cancer Res 2004 1.45
17 Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine. Oncotarget 2013 1.44
18 The use of "overall accuracy" to evaluate the validity of screening or diagnostic tests. J Gen Intern Med 2004 1.41
19 Recurrence after neoadjuvant chemoradiation and surgery for esophageal cancer: does the pattern of recurrence differ for patients with complete response and those with partial or no response? J Thorac Cardiovasc Surg 2009 1.27
20 Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus. Clin Cancer Res 2006 1.26
21 Are surgical outcomes for lung cancer resections improved at teaching hospitals? Ann Thorac Surg 2008 1.23
22 Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer. Cancer Res 2006 1.12
23 Hypermethylation of the GATA gene family in esophageal cancer. Int J Cancer 2006 1.12
24 Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer. J Pathol 2013 1.09
25 Promoter methylation of HIN-1 in the progression to esophageal squamous cancer. Epigenetics 2008 1.08
26 Decoding circulating nucleic acids in human serum using microfluidic single molecule spectroscopy. J Am Chem Soc 2010 1.05
27 Inactivation of the tissue inhibitor of metalloproteinases-2 gene by promoter hypermethylation in lymphoid malignancies. Oncogene 2005 0.99
28 Methylation of TFPI-2 is an early event of esophageal carcinogenesis. Epigenomics 2012 0.95
29 SOX17 methylation inhibits its antagonism of Wnt signaling pathway in lung cancer. Discov Med 2012 0.93
30 Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer. Int J Cancer 2007 0.93
31 Molecular margin analysis predicts local recurrence after sublobar resection of lung cancer. Int J Cancer 2005 0.92
32 Human immunodeficiency virus infection as a prognostic factor in surgical patients with non-small cell lung cancer. Ann Thorac Surg 2012 0.90
33 Inhibition of SOX17 by microRNA 141 and methylation activates the WNT signaling pathway in esophageal cancer. J Mol Diagn 2012 0.90
34 Long-term survival outcomes by smoking status in surgical and nonsurgical patients with non-small cell lung cancer: comparing never smokers and current smokers. Chest 2010 0.89
35 Epigenetic silencing of CXCL14 induced colorectal cancer migration and invasion. Discov Med 2013 0.89
36 Enzymatic incorporation of multiple dyes for increased sensitivity in QD-FRET sensing for DNA methylation detection. Chembiochem 2010 0.87
37 Epigenetic silencing of DACH1 induces the invasion and metastasis of gastric cancer by activating TGF-β signalling. J Cell Mol Med 2014 0.87
38 Extraction and processing of circulating DNA from large sample volumes using methylation on beads for the detection of rare epigenetic events. Clin Chim Acta 2013 0.87
39 Predictive value of CHFR and MLH1 methylation in human gastric cancer. Gastric Cancer 2014 0.86
40 Glutamate excitotoxicity mediates neuronal apoptosis after hypothermic circulatory arrest. Ann Thorac Surg 2010 0.85
41 Invited commentary: the etiology of lung cancer in men compared with women. Am J Epidemiol 2013 0.85
42 Tumor suppressor gene hypermethylation as a predictor of gastric stromal tumor behavior. J Gastrointest Surg 2003 0.84
43 Functional identification of cancer-specific methylation of CDO1, HOXA9, and TAC1 for the diagnosis of lung cancer. Clin Cancer Res 2014 0.83
44 A murine xenograft model of spontaneous metastases of human lung adenocarcinoma. J Surg Res 2011 0.82
45 Epigenetic changes associated with neoplasms of the exocrine and endocrine pancreas. Discov Med 2014 0.81
46 A handy tool to teach segmental liver anatomy to surgical trainees. Arch Surg 2012 0.81
47 Epigenetic changes and functional study of HOXA11 in human gastric cancer. Epigenomics 2015 0.81
48 Impact of elastic staining on the staging of peripheral lung cancers. Am J Surg Pathol 2007 0.80
49 Prospective CT screening for lung cancer in a high-risk population: HIV-positive smokers. J Thorac Oncol 2014 0.78
50 A case of ectopic parathyroid hormone production by a pulmonary neoplasm. J Thorac Cardiovasc Surg 2006 0.77
51 CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer. Cancer Biol Ther 2012 0.77
52 Lung cancer: new surgical approaches. Respirology 2007 0.75
53 Aortic and mitral valve disruption following nonpenetrating chest trauma. J Trauma 2002 0.75