Published in Sci Rep on January 01, 2013
Latent tuberculosis infection: myths, models, and molecular mechanisms. Microbiol Mol Biol Rev (2014) 1.06
Design and Construction of a Cloning Vector Containing the hspX Gene of Mycobacterium tuberculosis. Rep Biochem Mol Biol (2016) 0.75
T-cell quality in memory and protection: implications for vaccine design. Nat Rev Immunol (2008) 11.65
Tuberculosis. Lancet (2011) 8.07
Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding alpha -crystallin. Proc Natl Acad Sci U S A (2001) 7.65
Immunogenicity and protective efficacy of a tuberculosis DNA vaccine. Nat Med (1996) 5.38
The challenge of new drug discovery for tuberculosis. Nature (2011) 4.23
A multistage tuberculosis vaccine that confers efficient protection before and after exposure. Nat Med (2011) 4.09
Vaccination against tuberculosis by DNA injection. Nat Med (1996) 3.76
Mycobacterial stationary phase induced by low oxygen tension: cell wall thickening and localization of the 16-kilodalton alpha-crystallin homolog. J Bacteriol (1998) 3.43
Multifunctional, high-level cytokine-producing Th1 cells in the lung, but not spleen, correlate with protection against Mycobacterium tuberculosis aerosol challenge in mice. J Immunol (2008) 3.04
Therapy of tuberculosis in mice by DNA vaccination. Nature (1999) 2.99
Latent Mycobacterium tuberculosis-persistence, patience, and winning by waiting. Nat Med (2000) 2.97
Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells. J Immunol (2009) 2.72
Characterization of the major membrane protein of virulent Mycobacterium tuberculosis. Infect Immun (1992) 2.61
DNA vaccines: progress and challenges. J Immunol (2005) 2.34
Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis. Antimicrob Agents Chemother (2006) 2.18
Protective effect of DNA vaccine during chemotherapy on reactivation and reinfection of Mycobacterium tuberculosis. Gene Ther (2005) 1.66
Therapeutic immunization against Mycobacterium tuberculosis is an effective adjunct to antibiotic treatment. J Infect Dis (2012) 1.62
Human T- and B-cell reactivity to the 16kDa alpha-crystallin protein of Mycobacterium tuberculosis. Scand J Immunol (1998) 1.47
Identification, sequencing, and expression of Mycobacterium leprae superoxide dismutase, a major antigen. Infect Immun (1990) 1.37
Phenotypic definition of effector and memory T-lymphocyte subsets in mice chronically infected with Mycobacterium tuberculosis. Clin Vaccine Immunol (2010) 1.26
Immune responses to mycobacterial antigens in the Gambian population: implications for vaccines and immunodiagnostic test design. Infect Immun (2004) 1.21
Immune effects and mechanisms of action of CpG motifs. Vaccine (2000) 1.20
CpG oligodeoxynucleotides and interleukin-12 improve the efficacy of Mycobacterium bovis BCG vaccination in mice challenged with M. tuberculosis. Infect Immun (2000) 1.19
Therapeutic effect of DNA vaccines combined with chemotherapy in a latent infection model after aerosol infection of mice with Mycobacterium tuberculosis. Gene Ther (2003) 1.14
Characterization of B cell epitopes on the 16K antigen of Mycobacterium tuberculosis. Clin Exp Immunol (1992) 1.13
Enhanced and enduring protection against tuberculosis by recombinant BCG-Ag85C and its association with modulation of cytokine profile in lung. PLoS One (2008) 1.09
Human T cell responses to peptide epitopes of the 16-kD antigen in tuberculosis. Clin Exp Immunol (1995) 1.08
Immunotherapy with plasmid DNA encoding mycobacterial hsp65 in association with chemotherapy is a more rapid and efficient form of treatment for tuberculosis in mice. Gene Ther (2005) 1.05
Efficacy of Mycobacterium indicus pranii immunotherapy as an adjunct to chemotherapy for tuberculosis and underlying immune responses in the lung. PLoS One (2012) 1.05
Influence of HLA-DR on the phenotype of CD4+ T lymphocytes specific for an epitope of the 16-kDa alpha-crystallin antigen of Mycobacterium tuberculosis. Eur J Immunol (1999) 1.03
Chemotherapy of Mycobacterium tuberculosis infections in mice with a combination of isoniazid and rifampicin entrapped in Poly (DL-lactide-co-glycolide) microparticles. J Antimicrob Chemother (2001) 1.01
A booster vaccine expressing a latency-associated antigen augments BCG induced immunity and confers enhanced protection against tuberculosis. PLoS One (2011) 0.96
HLA-A2-restricted CD8+-cytotoxic-T-cell responses to novel epitopes in Mycobacterium tuberculosis superoxide dismutase, alanine dehydrogenase, and glutamine synthetase. Infect Immun (2004) 0.93
Enhancement of immunocompetence in tuberculosis by DNA vaccination. Vaccine (2000) 0.87
Tuberculosis vaccine development: The development of novel (preclinical) DNA vaccine. Hum Vaccin (2010) 0.87
DNA vaccines against mycobacterial diseases. Expert Rev Vaccines (2009) 0.86
Elicitation of efficient, protective immune responses by using DNA vaccines against tuberculosis. Vaccine (2005) 0.86
Latency antigen α-crystallin based vaccination imparts a robust protection against TB by modulating the dynamics of pulmonary cytokines. PLoS One (2011) 0.84
Mtb32 is a promising tuberculosis antigen for DNA vaccination in pre- and post-exposure mouse models. Gene Ther (2011) 0.83
Treatment of multi-drug-resistant tuberculosis in mice with DNA vaccines alone or in combination with chemotherapeutic drugs. Scand J Immunol (2011) 0.82
A major T-cell-inducing cytosolic 23 kDa protein antigen of the vaccine candidate Mycobacterium habana is superoxide dismutase. Microbiology (1996) 0.82
DNA vaccines against mycobacterial diseases. Future Microbiol (2006) 0.82
Therapeutic effects of Ag85B and MPT64 DNA vaccines in a murine model of Mycobacterium tuberculosis infection. Vaccine (2005) 0.80
Therapeutic DNA vaccines against tuberculosis: a promising but arduous task. Chin Med J (Engl) (2006) 0.78
Superoxide dismutase activity of Mycobacterium tuberculosis isolated from tuberculosis patients and the immunoreactivity of superoxide dismutase from M. tuberculosis H37Rv. Tuber Lung Dis (1993) 0.76
Disruption of mycobactin biosynthesis leads to attenuation of Mycobacterium tuberculosis for growth and virulence. J Infect Dis (2013) 1.70
Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs. Mol Microbiol (2003) 1.62
Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. Oncogene (2003) 1.58
Over-expression of superoxide dismutase obliterates the protective effect of BCG against tuberculosis by modulating innate and adaptive immune responses. Vaccine (2011) 1.44
Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels. Cancer Res (2002) 1.36
Polyphasic taxonomic analysis establishes Mycobacterium indicus pranii as a distinct species. PLoS One (2009) 1.36
Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3. Int J Cancer (2004) 1.35
Iron storage proteins are essential for the survival and pathogenesis of Mycobacterium tuberculosis in THP-1 macrophages and the guinea pig model of infection. J Bacteriol (2011) 1.28
The sigma factors of Mycobacterium tuberculosis: regulation of the regulators. FEBS J (2009) 1.26
Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance. Clin Cancer Res (2004) 1.25
Mycobacterial transcriptional signals: requirements for recognition by RNA polymerase and optimal transcriptional activity. Nucleic Acids Res (2006) 1.21
Role of Mycobacterium tuberculosis Ser/Thr kinase PknF: implications in glucose transport and cell division. J Bacteriol (2005) 1.21
mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol Lett (2003) 1.20
A computational pipeline for quantification of pulmonary infections in small animal models using serial PET-CT imaging. EJNMMI Res (2013) 1.17
Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis. Carcinogenesis (2002) 1.16
Serine threonine protein kinases of mycobacterial genus: phylogeny to function. Physiol Genomics (2006) 1.12
Functional studies of multiple thioredoxins from Mycobacterium tuberculosis. J Bacteriol (2008) 1.12
Mechanistic insights into a novel exporter-importer system of Mycobacterium tuberculosis unravel its role in trafficking of iron. PLoS One (2008) 1.12
Requirement of the mymA operon for appropriate cell wall ultrastructure and persistence of Mycobacterium tuberculosis in the spleens of guinea pigs. J Bacteriol (2005) 1.11
Enhanced and enduring protection against tuberculosis by recombinant BCG-Ag85C and its association with modulation of cytokine profile in lung. PLoS One (2008) 1.09
Cytotoxic activity of nucleoside diphosphate kinase secreted from Mycobacterium tuberculosis. Eur J Biochem (2003) 1.07
Synergistic anti-cancer effects of grape seed extract and conventional cytotoxic agent doxorubicin against human breast carcinoma cells. Breast Cancer Res Treat (2004) 1.05
Ferritin structure from Mycobacterium tuberculosis: comparative study with homologues identifies extended C-terminus involved in ferroxidase activity. PLoS One (2011) 1.03
Molecular analysis of a leprosy immunotherapeutic bacillus provides insights into Mycobacterium evolution. PLoS One (2007) 1.03
Structure-activity relationships in Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease. RNA (2009) 1.02
Facilitated oligomerization of mycobacterial GroEL: evidence for phosphorylation-mediated oligomerization. J Bacteriol (2009) 1.01
Calcium-binding proteins of Entamoeba histolytica. Arch Med Res (2006) 0.99
Crystal structure of Bfr A from Mycobacterium tuberculosis: incorporation of selenomethionine results in cleavage and demetallation of haem. PLoS One (2009) 0.98
Deciphering the genes involved in pathogenesis of Mycobacterium tuberculosis. Tuberculosis (Edinb) (2005) 0.98
Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes. J Mol Cell Biol (2012) 0.98
Phosphoprotein phosphatase of Mycobacterium tuberculosis dephosphorylates serine-threonine kinases PknA and PknB. Biochem Biophys Res Commun (2003) 0.97
A booster vaccine expressing a latency-associated antigen augments BCG induced immunity and confers enhanced protection against tuberculosis. PLoS One (2011) 0.96
Structural ordering of disordered ligand-binding loops of biotin protein ligase into active conformations as a consequence of dehydration. PLoS One (2010) 0.93
Dissecting the role of critical residues and substrate preference of a Fatty Acyl-CoA Synthetase (FadD13) of Mycobacterium tuberculosis. PLoS One (2009) 0.93
Important role of the nucleotide excision repair pathway in Mycobacterium smegmatis in conferring protection against commonly encountered DNA-damaging agents. Microbiology (2008) 0.92
Novel triphosphate phosphohydrolase activity of Clostridium thermocellum TTM, a member of the triphosphate tunnel metalloenzyme superfamily. J Biol Chem (2007) 0.90
Nuclear localization and in situ DNA damage by Mycobacterium tuberculosis nucleoside-diphosphate kinase. J Biol Chem (2004) 0.89
A distinct physiological role of MutY in mutation prevention in mycobacteria. Microbiology (2009) 0.89
Massive gene acquisitions in Mycobacterium indicus pranii provide a perspective on mycobacterial evolution. Nucleic Acids Res (2012) 0.88
Crystal structure and trimer-monomer transition of N-terminal domain of EhCaBP1 from Entamoeba histolytica. Biophys J (2010) 0.88
Role of 5'-TGN-3' motif in the interaction of mycobacterial RNA polymerase with a promoter of 'extended -10' class. FEMS Microbiol Lett (2003) 0.88
Secreted acid phosphatase (SapM) of Mycobacterium tuberculosis is indispensable for arresting phagosomal maturation and growth of the pathogen in guinea pig tissues. PLoS One (2013) 0.87
Expression and purification of recombinant antigens of Mycobacterium tuberculosis for application in serodiagnosis. Protein Expr Purif (2005) 0.87
Elicitation of efficient, protective immune responses by using DNA vaccines against tuberculosis. Vaccine (2005) 0.86
Expression and purification of recombinant 38-kDa and Mtb81 antigens of Mycobacterium tuberculosis for application in serodiagnosis. Protein Expr Purif (2005) 0.85
Skewing of the Th1/Th2 responses in mice due to variation in the level of expression of an antigen in a recombinant BCG system. Immunol Lett (2003) 0.85
Nucleoside diphosphate kinase of Mycobacterium tuberculosis acts as GTPase-activating protein for Rho-GTPases. FEBS Lett (2004) 0.85
Latency antigen α-crystallin based vaccination imparts a robust protection against TB by modulating the dynamics of pulmonary cytokines. PLoS One (2011) 0.84
Xanthan gum: an economical partial substitute for agar in microbial culture media. Curr Microbiol (2006) 0.83
Synergistic effects of UdgB and Ung in mutation prevention and protection against commonly encountered DNA damaging agents in Mycobacterium smegmatis. Microbiology (2009) 0.83
Development of the first oligonucleotide microarray for global gene expression profiling in guinea pigs: defining the transcription signature of infectious diseases. BMC Genomics (2012) 0.82
Crystallization and preliminary crystallographic analysis of cysteine synthase from Entamoeba histolytica. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.82
Immunogenicity of recombinant BCG vaccine strains overexpressing components of the antigen 85 complex of Mycobacterium tuberculosis. Med Microbiol Immunol (2003) 0.82
Inhibitors of Escherichia coli serine acetyltransferase block proliferation of Entamoeba histolytica trophozoites. Int J Parasitol (2007) 0.81
Endonuclease IV Is the major apurinic/apyrimidinic endonuclease in Mycobacterium tuberculosis and is important for protection against oxidative damage. PLoS One (2013) 0.80
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of bacterioferritin A from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.80
Secretory phosphatases deficient mutant of Mycobacterium tuberculosis imparts protection at the primary site of infection in guinea pigs. PLoS One (2013) 0.80
Molecular modeling studies of Fatty acyl-CoA synthetase (FadD13) from Mycobacterium tuberculosis--a potential target for the development of antitubercular drugs. J Mol Model (2010) 0.78
Diversity in functional organization of class I and class II biotin protein ligase. PLoS One (2011) 0.78
Thraustochytrium gaertnerium sp. nov.: a new thraustochytrid stramenopilan protist from mangroves of Goa, India. Protist (2005) 0.78
Structural biology of Mycobacterium tuberculosis proteins: the Indian efforts. Tuberculosis (Edinb) (2011) 0.77
Evaluation of wound-healing activity of Acorus calamus Linn. Nat Prod Res (2010) 0.77
Crystallization and preliminary X-ray diffraction analysis of biotin acetyl-CoA carboxylase ligase (BirA) from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.76
Identification of inhibitors against Mycobacterium tuberculosis thiamin phosphate synthase, an important target for the development of anti-TB drugs. PLoS One (2011) 0.76
Structural characterization of a novel Ca2+-binding protein from Entamoeba histolytica: structural basis for the observed functional differences with its isoform. J Biol Inorg Chem (2009) 0.76
Segmentation of PET images for computer-aided functional quantification of tuberculosis in small animal models. IEEE Trans Biomed Eng (2013) 0.76
Reply to Jones and Niederweis. J Infect Dis (2013) 0.76
Whole-cell screening-based identification of inhibitors against the intraphagosomal survival of Mycobacterium tuberculosis. Antimicrob Agents Chemother (2013) 0.75
Matrix-assisted refolding, purification and activity assessment using a 'form invariant' assay for matrix metalloproteinase 2 (MMP2). Mol Biotechnol (2014) 0.75
Differential proteomics approach to identify putative protective antigens of Mycobacterium tuberculosis presented during early stages of macrophage infection and their evaluation as DNA vaccines. Indian J Exp Biol (2015) 0.75
Unique residues at the 3-fold and 4-fold axis of mycobacterial ferritin are involved in oligomer switching. Biochemistry (2013) 0.75
RheuMetric A Physician Checklist to Record Patient Levels of Inflammation, Damage and Distress as Quantitative Data Rather than as Narrative Impressions. Bull Hosp Jt Dis (2013) (2015) 0.75
Novel UV-spectrophotometric method for quantitative estimation of furazolidone using mixed hydrotropic agent. Pak J Pharm Sci (2013) 0.75
ILMA as an Alternative to Face Mask Ventilation in a Case of Nasal Chondrosarcoma. J Neurosurg Anesthesiol (2017) 0.75