| Rank | Title | Journal | Year | PubWeight™‹?› |
|---|---|---|---|---|
| 1 | Diverse somatic mutation patterns and pathway alterations in human cancers. | Nature | 2010 | 10.83 |
| 2 | Recurrent R-spondin fusions in colon cancer. | Nature | 2012 | 5.10 |
| 3 | Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. | Nat Genet | 2012 | 4.70 |
| 4 | Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation. | Cancer Cell | 2009 | 4.47 |
| 5 | Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors. | PLoS One | 2009 | 2.07 |
| 6 | Oncogenic ERBB3 mutations in human cancers. | Cancer Cell | 2013 | 2.06 |
| 7 | Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110alpha and are disrupted in oncogenic p85 mutants. | Proc Natl Acad Sci U S A | 2009 | 1.46 |
| 8 | Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers. | Proc Natl Acad Sci U S A | 2012 | 1.22 |