Published in Eur J Clin Pharmacol on May 19, 2013
Registering clinical trials. JAMA (2003) 7.21
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Lancet (2004) 7.18
Clinical trial registration: transparency is the watchword. Lancet (2006) 4.17
Trial registration: a great idea switches from ignored to irresistible. JAMA (2004) 3.72
All trials must be registered and the results published. BMJ (2013) 3.46
Differences in reporting of analyses in internal company documents versus published trial reports: comparisons in industry-sponsored trials in off-label uses of gabapentin. PLoS Med (2013) 2.82
National and multinational prospective trial registers. Lancet (2008) 1.09
Clinical trial data as a public good. JAMA (2012) 1.05
Rare diseases: what's next? Lancet (2008) 3.06
Smoking in Italy 2005-2006: effects of a comprehensive National Tobacco Regulation. Prev Med (2007) 2.61
Orphan drug development is not taking off. Br J Clin Pharmacol (2009) 2.27
Risk sharing arrangements for pharmaceuticals: potential considerations and recommendations for European payers. BMC Health Serv Res (2010) 2.21
A literature review on off-label drug use in children. Eur J Pediatr (2005) 1.89
Orphan drug development is progressing too slowly. Br J Clin Pharmacol (2006) 1.79
Drug utilisation profile in the Italian paediatric population. Eur J Pediatr (2008) 1.67
Disappointing biotech. BMJ (2005) 1.66
Errors in the approval process and post-marketing evaluation of drotrecogin alfa (activated) for the treatment of severe sepsis. Lancet Infect Dis (2009) 1.55
Anything new in EU pharmacovigilance? Eur J Clin Pharmacol (2011) 1.53
Antibiotic prescription and prevalence rate in the outpatient paediatric population: analysis of surveys published during 2000-2005. Eur J Clin Pharmacol (2007) 1.45
Mild depression in general practice: is the automatism of antidepressant prescribing an evidence-based approach? Acta Psychiatr Scand (2006) 1.42
Children need international formulary to guarantee rational use of drugs. BMJ (2004) 1.41
Varying and "atypical" indications for atypical antipsychotics. Psychopharmacology (Berl) (2003) 1.40
Review of Italian primary care paediatricians identifies 38 commonly prescribed drugs for children. Acta Paediatr (2014) 1.40
Orphan drugs, orphan diseases. The first decade of orphan drug legislation in the EU. Eur J Clin Pharmacol (2012) 1.39
Italy must invest more in science and technology. Nature (2008) 1.38
Differences in antibiotic prescribing in paediatric outpatients. Arch Dis Child (2011) 1.38
Asthma diagnosis vs. analysis of anti-asthmatic prescriptions to identify asthma in children. Eur J Clin Pharmacol (2011) 1.26
Follow up of quality of public oriented health information on the world wide web: systematic re-evaluation. BMJ (2002) 1.19
Drug prescriptions to outpatient children: a review of the literature. Eur J Clin Pharmacol (2009) 1.16
Off-label and unlicensed drug utilization in hospitalized children in Fortaleza, Brazil. Eur J Clin Pharmacol (2008) 1.16
Inappropriate use of anti-asthmatic drugs in the Italian paediatric population. Eur J Clin Pharmacol (2003) 1.10
Italian paediatricians and off-label prescriptions: loyal to regulatory or guideline standards? Acta Paediatr (2005) 1.09
Pregnancy outcome after cabergoline treatment in early weeks of gestation. Reprod Toxicol (2002) 1.09
More and better should be done to guarantee evidence-based management of ADHD in children across Europe. Eur J Pediatr (2013) 1.09
Anti-asthma medication prescribing to children in the Lombardy Region of Italy: chronic versus new users. BMC Pulm Med (2011) 1.04
Inter-country variations in anti-asthmatic drug prescriptions for children. Systematic review of studies published during the 2000-2009 period. Eur J Clin Pharmacol (2010) 1.01
Anti-asthmatic drug prescriptions to an Italian paedriatic population. Pediatr Allergy Immunol (2008) 1.00
Enhancing the rational use of new medicines across European health care systems. Eur J Clin Pharmacol (2008) 0.99
Randomised controlled trials of selective serotonin reuptake inhibitors in treating depression in children and adolescents: a systematic review and meta-analysis. Eur Neuropsychopharmacol (2007) 0.99
Reconsidering the Declaration of Helsinki. Lancet (2013) 0.98
Fish oil and mental health: the role of n-3 long-chain polyunsaturated fatty acids in cognitive development and neurological disorders. Int Clin Psychopharmacol (2006) 0.95
Cardiovascular measures in children and adolescents with attention-deficit/hyperactivity disorder who are new users of methylphenidate and atomoxetine. J Child Adolesc Psychopharmacol (2012) 0.95
The regional profile of antibiotic prescriptions in Italian outpatient children. Eur J Clin Pharmacol (2012) 0.94
Use of psychotropic medications in Italian children and adolescents. Eur J Pediatr (2006) 0.94
Determinants of the drug utilization profile in the paediatric population in Italy's Lombardy Region. Br J Clin Pharmacol (2009) 0.93
Fluoxetine dose and outcome in antidepressant drug trials. Eur J Clin Pharmacol (2002) 0.90
A double-blind, placebo-controlled, randomized trial of bupropion for smoking cessation in primary care. Arch Intern Med (2007) 0.89
European survey on the use of prophylactic fluconazole in neonatal intensive care units. Eur J Pediatr (2011) 0.89
Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial. BMC Pediatr (2011) 0.88
Tuberculosis care for pregnant women: a systematic review. BMC Infect Dis (2014) 0.88
One-year prospective follow-up of pharmacological treatment in children with attention-deficit/hyperactivity disorder. Eur J Clin Pharmacol (2011) 0.88
Incremental cost per quality-adjusted life year gained? The need for alternative methods to evaluate medical interventions for ultra-rare disorders. J Comp Eff Res (2014) 0.87
Antidepressant and antipsychotic use in an Italian pediatric population. BMC Pediatr (2011) 0.86
Withdrawal of 'Xigris' from the market: old and new lessons. J Epidemiol Community Health (2012) 0.86
Pre-market clinical evaluations of innovative high-risk medical devices in Europe. Int J Technol Assess Health Care (2012) 0.86
Drug use profile in outpatient children and adolescents in different Italian regions. BMC Pediatr (2013) 0.86
Drug sales in four European countries still differ. BMJ (2003) 0.85
Flaws in animal studies exploring statins and impact on meta-analysis. Eur J Clin Invest (2014) 0.84
Thrombolysis or nothing for acute myocardial infarction? It's all the same! Br J Clin Pharmacol (2008) 0.84
Regulatory policies on medicines for psychiatric disorders: is Europe on target? Br J Psychiatry (2007) 0.84
Increase in non-evidence based use of antidepressants in children is cause for concern. BMJ (2004) 0.84
Smoke-free legislation and asthma. N Engl J Med (2011) 0.84
Independent clinical research in Europe. Lancet (2004) 0.83
Spirometry testing in a population of Italian children: age and gender differences. Respir Med (2012) 0.83
Role of presynaptic alpha2-adrenoceptors in antidepressant action: recent findings from microdialysis studies. Prog Neuropsychopharmacol Biol Psychiatry (2004) 0.82
Wide intra- and inter-country variability in drug use and dosage in very-low-birth-weight newborns with severe infections. Eur J Clin Pharmacol (2012) 0.82
Haematological anticancer drugs in Europe: any added value at the time of approval? Eur J Clin Pharmacol (2007) 0.82
Effectiveness of nebulized beclomethasone in preventing viral wheezing: an RCT. Pediatrics (2014) 0.82
New antirheumatic drugs: any real added value? A critical overview of regulatory criteria for their marketing approval. Eur J Clin Pharmacol (2007) 0.82
Patient organizations' funding from pharmaceutical companies: is disclosure clear, complete and accessible to the public? An Italian survey. PLoS One (2012) 0.82
Geographical epidemiology of antibacterials in the preschool age. Int J Health Geogr (2012) 0.81
Most appropriate animal models to study the efficacy of statins: a systematic review. Eur J Clin Invest (2014) 0.81
Methods in pharmacoepidemiology: a review of statistical analyses and data reporting in pediatric drug utilization studies. Eur J Clin Pharmacol (2012) 0.81
Neonatal toxicity following maternal citalopram treatment. Fetal Pediatr Pathol (2013) 0.81
The DEC-net European register of paediatric drug therapy trials: contents and context. Eur J Clin Pharmacol (2008) 0.81
Having your cake and eating it: office of fair trading proposal for funding new drugs to benefit patients and innovative companies. Pharmacoeconomics (2008) 0.81
Differences in the drug prescriptions to children by Italian paediatricians and general practitioners. Eur J Clin Pharmacol (2010) 0.81
Europe also needs agency for postmarketing surveillance. BMJ (2005) 0.80
European regulatory policies on medicines and public health needs. Eur J Public Health (2003) 0.80
Italian attention-deficit/hyperactivity disorder registry. Pediatrics (2004) 0.80
Quality of cystic fibrosis information on Italian websites. Inform Health Soc Care (2009) 0.79
Off-label drug use in children should be rational. Arch Dis Child (2011) 0.79
Fast and reliable artemisinin determination from different Artemisia annua leaves based alimentary products by high performance liquid chromatography-tandem mass spectrometry. Food Chem (2013) 0.79
Predicting the clinical relevance of drug interactions from pre-approval studies. Drug Saf (2009) 0.79
New drugs for thromboprophylaxis in atrial fibrillation. Eur J Intern Med (2011) 0.79
Time to revisit the orphan drug law. Eur J Clin Pharmacol (2011) 0.78
CNS drugs approved by the centralised European procedure: true innovation or dangerous stagnation? Psychopharmacology (Berl) (2006) 0.78
Psychotropic drug use during breastfeeding: a review of the evidence. Pediatrics (2009) 0.78
EMA's reflection on placebo does not reflect patients' interests. Eur J Clin Pharmacol (2011) 0.78
Registration of trials in children: update of current international initiatives. Arch Dis Child (2009) 0.78
Ocular medicines in children: the regulatory situation related to clinical research. BMC Pediatr (2012) 0.78
Bevacizumab and ranibizumab. A matter of public interest. BMJ (2010) 0.77
A new anti-cancer drug in the market: Good news for investors or for patients? Eur J Cancer (2008) 0.77
Confidentiality. Lancet (2003) 0.77
Antipsychotic drug toxicology in children. Expert Opin Drug Metab Toxicol (2011) 0.77
NSAIDs during pregnancy and risk of miscarriage: true risks or only suspicions? BMJ (2004) 0.77
Burden of psychiatric disorders in the pediatric population. Eur Neuropsychopharmacol (2012) 0.77
Seasonal influenza immunization in early infancy? BMC Public Health (2012) 0.76
The awareness among paediatricians of off-label prescribing in children: a survey of Italian hospitals. Eur J Clin Pharmacol (2006) 0.75
Attention-deficit/hyperactivity disorder drugs and growth: an Italian prospective observational study. J Child Adolesc Psychopharmacol (2013) 0.75
Do children really need more research on respiratory drugs? Acta Paediatr (2010) 0.75
Is there discrimination in access to therapy for HCV patients? J Hepatol (2008) 0.75
Exenatide for type 2 diabetes. Lancet (2009) 0.75
Controlling cervical cancer. Pharmacoeconomics (2009) 0.75
Discontinuation of Vioxx. Lancet (2005) 0.75
Effects of physical inactivity on non-communicable diseases. Lancet (2012) 0.75
Childhood asthma management pre- and post-incident asthma hospitalization. PLoS One (2013) 0.75