Age related changes in hormone binding by target cells and tissues; possible role in altered adaptive responsiveness.

PubWeight™: 0.81‹?›

🔗 View Article (PMID 236910)

Published in Exp Gerontol on February 01, 1975

Authors

G S Roth, R C Adelman

Articles by these authors

(truncated to the top 100)

Extending the lifespan of long-lived mice. Nature (2001) 2.98

Balanced macromolecular biosynthesis in "protoplasts" of Streptococcus faecalis. J Bacteriol (1971) 2.77

Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents. Proc Natl Acad Sci U S A (1996) 2.23

Promotion of wound repair in old mice by local injection of macrophages. Proc Natl Acad Sci U S A (1989) 1.82

Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory end points. Am J Physiol (1995) 1.72

Reduced beta-adrenergic receptor concentrations in ageing man. Nature (1977) 1.59

Nutritional modulation of aging in nonhuman primates. J Nutr Health Aging (1999) 1.57

Activity measures in rhesus monkeys on long-term calorie restriction. Physiol Behav (1997) 1.44

Hormone receptor changes during adulthood and senescence: significance for aging research. Fed Proc (1979) 1.38

A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys. Proc Natl Acad Sci U S A (2001) 1.35

Caloric restriction in primates. Ann N Y Acad Sci (2001) 1.33

Cellular proliferation potential during aging and caloric restriction in rhesus monkeys (Macaca mulatta). J Cell Physiol (1999) 1.33

Studies of aging in ames dwarf mice: Effects of caloric restriction. J Am Aging Assoc (2000) 1.23

Caloric restriction mimetics: metabolic interventions. J Gerontol A Biol Sci Med Sci (2001) 1.22

Calorie restriction in nonhuman primates: effects on diabetes and cardiovascular disease risk. Toxicol Sci (1999) 1.22

Short-term calorie restriction improves disease-related markers in older male rhesus monkeys (Macaca mulatta). Mech Ageing Dev (2000) 1.19

Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway. J Biol Chem (1998) 1.17

Purification and properties of rat liver fructokinase. J Biol Chem (1967) 1.17

Beyond the rodent model: Calorie restriction in rhesus monkeys. Age (Omaha) (1997) 1.14

Contractile and biochemical correlates of beta-adrenergic stimulation of the aged heart. Am J Physiol (1980) 1.13

Longevity and the genetic determination of collagen glycoxidation kinetics in mammalian senescence. Proc Natl Acad Sci U S A (1996) 1.13

Caloric restriction increases HDL2 levels in rhesus monkeys (Macaca mulatta). Am J Physiol (1997) 1.10

Strategy for identifying biomarkers of aging in long-lived species. Exp Gerontol (2001) 1.08

Aging and food restriction alter some indices of bone metabolism in male rhesus monkeys (Macaca mulatta). J Nutr (1995) 1.07

Structural relations in aldolases purified from rat liver and muscle and Novikoff hepatoma. Arch Biochem Biophys (1970) 1.04

Metabolic regulation and enzyme alterations in the Morris hepatomas. Cancer Res (1968) 1.03

Dietary and hormonal regulation of enzymes of fructose metabolism in rat liver. J Biol Chem (1966) 1.01

Age-related decline in mitogen-activated protein kinase activity in epidermal growth factor-stimulated rat hepatocytes. J Biol Chem (1996) 1.00

The role of peroxisomes in aging. Cell Mol Life Sci (1998) 1.00

Dehydroepiandrosterone sulfate: a biomarker of primate aging slowed by calorie restriction. J Clin Endocrinol Metab (1997) 1.00

Energy balance in rhesus monkeys (Macaca mulatta) subjected to long-term dietary restriction. J Gerontol A Biol Sci Med Sci (1995) 1.00

Effect of caloric restriction on the 24-hour plasma DHEAS and cortisol profiles of young and old male rhesus macaques. Ann N Y Acad Sci (2004) 0.99

Wound repair in mice as influenced by age and antimacrophage serum. J Gerontol (1987) 0.97

A strategy for identifying biomarkers of aging: further evaluation of hematology and blood chemistry data from a calorie restriction study in rhesus monkeys. Exp Gerontol (1998) 0.97

beta-Adrenergic regulation of protein phosphorylation and its relationship to exocrine secretion in dispersed rat parotid gland acinar cells. J Biol Chem (1981) 0.95

A nonhuman primate model of age-related bone loss: a longitudinal study in male and premenopausal female rhesus monkeys. Bone (2001) 0.94

D2 dopamine receptors stimulate mitogenesis through pertussis toxin-sensitive G proteins and Ras-involved ERK and SAP/JNK pathways in rat C6-D2L glioma cells. J Neurochem (1998) 0.92

Dietary and hormonal effects on adenosine triphosphate: adenosine monophosphate phosphotransferase activity in rat liver. J Biol Chem (1968) 0.92

Incorporation of radioactive macromolecular precursors into intact cells and osmotically stabilized "protoplasts" of Streptococcus faecalis. J Bacteriol (1971) 0.92

Changes in blood chemistry and hematology variables during aging in captive rhesus macaques (Macaca mulatta). J Med Primatol (2001) 0.92

Dietary restriction in nonhuman primates: progress report on the NIA study. Ann N Y Acad Sci (1992) 0.91

Amyloid beta-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons. Proc Natl Acad Sci U S A (1996) 0.91

Altered ovarian regulation of wound healing during aging. Proc Soc Exp Biol Med (1981) 0.90

Impaired hormonal regulation of enzyme activity during aging. Fed Proc (1975) 0.90

Aging and caloric restriction in nonhuman primates: behavioral and in vivo brain imaging studies. Ann N Y Acad Sci (2001) 0.90

Death of PC12 cells and hippocampal neurons induced by adenoviral-mediated FAD human amyloid precursor protein gene expression. J Neurosci Res (1999) 0.89

Age-related decline in striatal volume in monkeys as measured by magnetic resonance imaging. Neurobiol Aging (2000) 0.89

Energy restriction does not alter bone mineral metabolism or reproductive cycling and hormones in female rhesus monkeys. J Nutr (2001) 0.88

Beta-adrenergic regulation of rat parotid gland exocrine protein secretion during aging. Mech Ageing Dev (1981) 0.88

Intrastriatal dopamine injection induces apoptosis through oxidation-involved activation of transcription factors AP-1 and NF-kappaB in rats. Mol Pharmacol (1999) 0.88

Changes in blood chemistry and hematology variables during aging in captive rhesus macaques (Macaca mulatta). J Med Primatol 30:161-173, 2001. J Med Primatol (2004) 0.87

Alpha1-adrenergic stimulation of phosphatidylinositol-phosphatidic acid turnover in rat parotid cells. Mol Pharmacol (1982) 0.87

Changes in the mechanisms of hormone and neurotransmitter action during aging: current status of the role of receptor and post-receptor alterations. A review. Mech Ageing Dev (1982) 0.87

Intracellular localization of ribosome biosynthesis in osmotically fragile forms of Streptococcus faecalis. Biochim Biophys Acta (1971) 0.87

Accelerated wound repair in old deer mice (Peromyscus maniculatus) and white-footed mice (Peromyscus leucopus). J Gerontol (1987) 0.86

Accuracy and precision of dual-energy X-ray absorptiometry for body composition measurements in rhesus monkeys. J Med Primatol (2001) 0.86

Loss of D2 receptor binding with age in rhesus monkeys: importance of correction for differences in striatal size. J Cereb Blood Flow Metab (1999) 0.86

Dietary restriction in rhesus monkeys: lymphopenia and reduced mitogen-induced proliferation in peripheral blood mononuclear cells. Aging (Milano) (1997) 0.86

Changes in the mechanisms of steroid action during aging. J Steroid Biochem (1979) 0.86

Adenylate kinase activity in rat liver. Adv Enzyme Regul (1968) 0.86

Molecular mechanisms of impaired stimulation of DNA synthesis in cultured hepatocytes of aged rats. Am J Physiol (1998) 0.86

Calorie restriction and skeletal mass in rhesus monkeys (Macaca mulatta): evidence for an effect mediated through changes in body size. J Gerontol A Biol Sci Med Sci (2001) 0.86

Age-related changes in activation of mitogen-activated protein kinase cascades by oxidative stress. J Investig Dermatol Symp Proc (1998) 0.85

Processing of Alzheimer's amyloid precursor protein during H2O2-induced apoptosis in human neuronal cells. Biochem Biophys Res Commun (1997) 0.85

Disruptions in enzyme regulation during aging. Basic Life Sci (1975) 0.85

Plasma concentrations of glucose, insulin, and percent glycosylated hemoglobin are unaltered by food restriction in rhesus and squirrel monkeys. J Gerontol (1992) 0.85

Evaluating measures of hematology and blood chemistry in male rhesus monkeys as biomarkers of aging. Exp Gerontol (1994) 0.85

Dissociation of striatal GTPase and dopamine release responses to muscarinic cholinergic agonists in F344 rats: influence of age and dietary manipulation. J Neurochem (1995) 0.84

The roles of dopamine oxidative stress and dopamine receptor signaling in aging and age-related neurodegeneration. Antioxid Redox Signal (2000) 0.84

Changes in G protein-mediated signal transduction in aging and Alzheimer's disease. Ann N Y Acad Sci (1993) 0.84

A possible role for insulin in the altered capability for hepatic enzyme adaptation during aging. Biochem Biophys Res Commun (1976) 0.84

Hormone action during aging: alterations and mechanisms. Mech Ageing Dev (1979) 0.84

Identification of neuronal programmed cell death in situ in the striatum of normal adult rat brain and its relationship to neuronal death during aging. Brain Res (1995) 0.83

Modulation of rat parotid cell alpha-adrenergic responsiveness at a step subsequent to receptor activation. J Biol Chem (1982) 0.83

Delayed loss of striatal dopamine receptors during aging of dietarily restricted rats. Brain Res (1984) 0.82

Longitudinal study of aging in monkeys: effects of diet restriction. Neurobiol Aging (1994) 0.82

Application of gene therapy to treat age-related loss of dopamine D2 receptor. Exp Gerontol (1999) 0.82

Human implications of caloric restriction's effects on aging in laboratory animals: an overview of opportunities for research. J Gerontol A Biol Sci Med Sci (2001) 0.82

Altered regulation of insulin secretion in isolated islets of different sizes in aging rats. Biochem Biophys Res Commun (1979) 0.82

Influence of age, sex, and dietary restriction on intracellular free calcium responses of CD4+ lymphocytes in rhesus monkeys (Macaca mulatta). J Cell Physiol (1995) 0.82

Evidence for a substrate-mediated change in conformation of rabbit muscle aldolase. Arch Biochem Biophys (1968) 0.82

Effect of aging on EGF stimulated DNA synthesis and EGF receptor levels in primary cultured rat hepatocytes. Biochem Biophys Res Commun (1993) 0.82

Age-related decline in Ras/ERK mitogen-activated protein kinase cascade is linked to a reduced association between Shc and EGF receptor. J Gerontol A Biol Sci Med Sci (2000) 0.81

Age-dependent regulation of glucokinase and tyrosine aminotransferase activities of rat liver in vivo by adrenal, pancreatic and pituitary hormones. Endocrinology (1972) 0.81

Peroxisomal disease cell lines with cellular plasmalogen deficiency have impaired muscarinic cholinergic signal transduction activity and amyloid precursor protein secretion. Biochem Biophys Res Commun (1998) 0.81

K+ release from rat parotid cells: an alpha 1-adrenergic mediated event. Biochem Pharmacol (1982) 0.81

Age-related changes in the nigrostriatum: a behavioral and biochemical analysis. J Gerontol (1978) 0.81

Age-dependent effects in enzyme induction--a biochemical expression of aging. Exp Gerontol (1971) 0.81

Evidence for a large thyrotropin and its accumulation during aging in rats. Biochem Biophys Res Commun (1977) 0.81

Cholinergic systems in aging: the role of oxidative stress. Clin Neuropharmacol (1992) 0.81

Development of dopamine receptor denervation supersensitivity in the neostriatum of the senescent rat. Life Sci (1981) 0.81

Locomotor activity in female rhesus monkeys: assessment of age and calorie restriction effects. J Gerontol A Biol Sci Med Sci (2000) 0.81

Breath ethane as a marker of reactive oxygen species during manipulation of diet and oxygen tension in rats. J Appl Physiol (1985) (1999) 0.80

Impaired down-regulation of pituitary dopamine receptors by estradiol in aged rats. Proc Soc Exp Biol Med (1989) 0.80

Reappraisal of biological ageing. Nature (1970) 0.80

In vivo imaging of adenovirus-mediated over-expression of dopamine D2 receptors in rat striatum by positron emission tomography. Neuroreport (2000) 0.80

Effect of age on sensitivity to pain and brain opiate receptors. Neurobiol Aging (1981) 0.80

Age-related changes in specific glucocorticoid binding by steroid-responsive tissues of rats. Endocrinology (1974) 0.80

Loss of rat ventricular alpha 1-adrenergic receptors during aging. Life Sci (1982) 0.80

Discordant effects of aging on prolactin and luteinizing hormone-beta messenger ribonucleic acid levels in the female rat. Endocrinology (1990) 0.80