Published in Clin Exp Metastasis on June 06, 2013
The eEF1A Proteins: At the Crossroads of Oncogenesis, Apoptosis, and Viral Infections. Front Oncol (2015) 0.89
miR-663 attenuates tumor growth and invasiveness by targeting eEF1A2 in pancreatic cancer. Mol Cancer (2015) 0.89
Serum MMP7, MMP10 and MMP12 level as negative prognostic markers in colon cancer patients. BMC Cancer (2016) 0.84
Knockdown of OCT4 suppresses the growth and invasion of pancreatic cancer cells through inhibition of the AKT pathway. Mol Med Rep (2014) 0.82
Luteolin decreases invasiveness, deactivates STAT3 signaling, and reverses interleukin-6 induced epithelial-mesenchymal transition and matrix metalloproteinase secretion of pancreatic cancer cells. Onco Targets Ther (2015) 0.79
Eukaryotic elongation factor-1α 2 knockdown inhibits hepatocarcinogenesis by suppressing PI3K/Akt/NF-κB signaling. World J Gastroenterol (2016) 0.77
Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells. Onco Targets Ther (2016) 0.75
Meta-analysis of gene expression and integrin-associated signaling pathways in papillary renal cell carcinoma subtypes. Oncotarget (2016) 0.75
Overexpression of eukaryotic elongation factor 1 alpha-2 is associated with poorer prognosis in patients with gastric cancer. J Cancer Res Clin Oncol (2015) 0.75
The EEF1A2 gene expression as risk predictor in localized prostate cancer. BMC Urol (2017) 0.75
Cancer statistics, 2012. CA Cancer J Clin (2012) 87.38
Pancreatic cancer. N Engl J Med (2010) 13.88
A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med (2004) 13.34
EMT and dissemination precede pancreatic tumor formation. Cell (2012) 9.27
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res (2003) 3.58
Regulation of peptide-chain elongation in mammalian cells. Eur J Biochem (2002) 2.86
RNA-mediated response to heat shock in mammalian cells. Nature (2006) 2.79
Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production. FASEB J (2001) 2.55
Translation elongation factor 1A is essential for regulation of the actin cytoskeleton and cell morphology. Nat Struct Mol Biol (2005) 2.15
The role of Shp2 (PTPN11) in cancer. Curr Opin Genet Dev (2007) 1.97
Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway. Cell Signal (2006) 1.87
Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer. Cell Signal (2008) 1.81
Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer. Nat Genet (2002) 1.70
Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. Int J Cancer (1995) 1.67
Matrix metalloproteinases in cancer. Essays Biochem (2002) 1.65
TGF-beta1-induced PI3K/Akt/NF-kappaB/MMP9 signalling pathway is activated in Philadelphia chromosome-positive chronic myeloid leukaemia hemangioblasts. J Biochem (2011) 1.59
Elongation factor-1 alpha is an overexpressed actin binding protein in metastatic rat mammary adenocarcinoma. J Cell Sci (1996) 1.56
Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells. Proc Natl Acad Sci U S A (1994) 1.50
Identification of putative oncogenes in lung adenocarcinoma by a comprehensive functional genomic approach. Oncogene (2006) 1.44
Tissue-dependent variation in the expression of elongation factor-1 alpha isoforms: isolation and characterisation of a cDNA encoding a novel variant of human elongation-factor 1 alpha. Eur J Biochem (1993) 1.41
eEF1A2 activates Akt and stimulates Akt-dependent actin remodeling, invasion and migration. Oncogene (2006) 1.41
Translation elongation factor eEF1A2 is a potential oncoprotein that is overexpressed in two-thirds of breast tumours. BMC Cancer (2005) 1.33
Tissue-specific expression in mammalian brain, heart, and muscle of S1, a member of the elongation factor-1 alpha gene family. J Biol Chem (1992) 1.27
Mouse translation elongation factor eEF1A-2 interacts with Prdx-I to protect cells against apoptotic death induced by oxidative stress. J Cell Biochem (2007) 1.14
Cleavage of lumican by membrane-type matrix metalloproteinase-1 abrogates this proteoglycan-mediated suppression of tumor cell colony formation in soft agar. Cancer Res (2004) 1.10
Amplification and overexpression of aurora kinase A (AURKA) in immortalized human ovarian epithelial (HOSE) cells. Mol Carcinog (2005) 1.08
Interactions of eukaryotic elongation factor 2 with actin: a possible link between protein synthetic machinery and cytoskeleton. FEBS Lett (1994) 1.07
Candidate metastasis-associated genes of the rat 13762NF mammary adenocarcinoma. Breast Cancer Res Treat (1993) 1.04
Identification of liver metastasis-related genes in a novel human pancreatic carcinoma cell model by microarray analysis. Cancer Lett (2009) 1.02
A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules. Int J Biochem Cell Biol (2007) 0.98
Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation. PLoS One (2009) 0.97
The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade. Biochimie (2007) 0.96
Elongation Factor 1 alpha interacts with phospho-Akt in breast cancer cells and regulates their proliferation, survival and motility. Mol Cancer (2009) 0.95
Eef1a2 promotes cell growth, inhibits apoptosis and activates JAK/STAT and AKT signaling in mouse plasmacytomas. PLoS One (2010) 0.94
Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression. Br J Cancer (2011) 0.92
Expression of matrix metalloproteinase 9 in pancreatic ductal carcinoma is associated with tumor metastasis formation. Folia Histochem Cytobiol (2007) 0.91
Regulation and functional role of eEF1A2 in pancreatic carcinoma. Biochem Biophys Res Commun (2009) 0.90
Enhancement of metastatic ability by ectopic expression of ST6GalNAcI on a gastric cancer cell line in a mouse model. Clin Exp Metastasis (2012) 0.83
eEF1A2 protein expression correlates with lymph node metastasis and decreased survival in pancreatic ductal adenocarcinoma. Hepatogastroenterology (2012) 0.82
Publication bias in editorial decision making. JAMA (2002) 3.52
Immune-related microRNAs are abundant in breast milk exosomes. Int J Biol Sci (2011) 2.11
Contrast-enhanced EUS for differential diagnosis of pancreatic mass lesions: a meta-analysis. Gastrointest Endosc (2012) 1.73
Hysterectomy compared with endometrial ablation for dysfunctional uterine bleeding: a randomized controlled trial. Obstet Gynecol (2007) 1.64
Synthesis and fungicidal evaluation of 2-arylphenyl ether-3-(1H-1,2,4-triazol-1-yl)propan-2-ol derivatives. J Agric Food Chem (2009) 1.56
Microfluidic PicoArray synthesis of oligodeoxynucleotides and simultaneous assembling of multiple DNA sequences. Nucleic Acids Res (2004) 1.53
MicroRNAome of porcine pre- and postnatal development. PLoS One (2010) 1.40
A comprehensive sequence and disease correlation analyses for the C-terminal region of CagA protein of Helicobacter pylori. PLoS One (2009) 1.34
The effects of Gd3+ substitution on the crystal structure, site symmetry, and photoluminescence of Y/Eu layered rare-earth hydroxide (LRH) nanoplates. Dalton Trans (2011) 1.31
Expression modification of uncoupling proteins and MnSOD in retinal endothelial cells and pericytes induced by high glucose: the role of reactive oxygen species in diabetic retinopathy. Exp Eye Res (2006) 1.20
Phase I, first-in-human study of BMS747158, a novel 18F-labeled tracer for myocardial perfusion PET: dosimetry, biodistribution, safety, and imaging characteristics after a single injection at rest. J Nucl Med (2011) 1.18
A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls. J Alzheimers Dis (2013) 1.18
A leaky mutation in DWARF4 reveals an antagonistic role of brassinosteroid in the inhibition of root growth by jasmonate in Arabidopsis. Plant Physiol (2009) 1.06
Association between time interval to publication and statistical significance. JAMA (2002) 1.03
Cervical nodal metastases of unresectable thoracic esophageal squamous cell carcinoma: characteristics of long-term survivors after concurrent chemoradiotherapy. Radiother Oncol (2011) 1.01
XAF1 as a prognostic biomarker and therapeutic target in pancreatic cancer. Cancer Sci (2009) 0.97
PepCyber:P~PEP: a database of human protein protein interactions mediated by phosphoprotein-binding domains. Nucleic Acids Res (2007) 0.94
The prognostic value of immunohistochemical subtyping in Chinese patients with de novo diffuse large B-cell lymphoma undergoing CHOP or R-CHOP treatment. Ann Hematol (2009) 0.94
Accurate preoperative staging of gastric cancer with combined endoscopic ultrasonography and PET-CT. Tohoku J Exp Med (2012) 0.93
Using interrupted time series design to analyze changes in hand, foot, and mouth disease incidence during the declining incidence periods of 2008-2010 in China. Biomed Environ Sci (2012) 0.93
A 2008 questionnaire-based survey of gastroesophageal reflux disease and related diseases by physicians in East Asian countries. Digestion (2009) 0.92
Structure--activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers. J Biol Chem (2004) 0.92
The calcium-sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone in neonates. J Bone Miner Res (2011) 0.91
Association of genetic polymorphism in GH gene with milk production traits in Beijing Holstein cows. J Biosci (2005) 0.90
Regulation and functional role of eEF1A2 in pancreatic carcinoma. Biochem Biophys Res Commun (2009) 0.90
Blood-retinal barrier breakdown induced by activation of protein kinase C via vascular endothelial growth factor in streptozotocin-induced diabetic rats. Curr Eye Res (2004) 0.89
Computational elucidation of the internal oxidant-controlled reaction pathways in Rh(III)-catalyzed aromatic C-H functionalization. J Org Chem (2012) 0.89
Use of tissue-engineered nerve grafts consisting of a chitosan/poly(lactic-co-glycolic acid)-based scaffold included with bone marrow mesenchymal cells for bridging 50-mm dog sciatic nerve gaps. Tissue Eng Part A (2010) 0.88
Endoscopic ultrasound elastography for differential diagnosis of pancreatic masses: a meta-analysis. Dig Dis Sci (2013) 0.87
HO-1 gene overexpression enhances the beneficial effects of superparamagnetic iron oxide labeled bone marrow stromal cells transplantation in swine hearts underwent ischemia/reperfusion: an MRI study. Basic Res Cardiol (2009) 0.87
Transcription factor WRKY70 displays important but no indispensable roles in jasmonate and salicylic acid signaling. J Integr Plant Biol (2008) 0.87
Natural Orifice Translumenal Endoscopic Surgery (NOTES): patients' perceptions and attitudes. Dig Dis Sci (2011) 0.87
Congenital left ventricular diverticulum diagnosed by echocardiography. Pediatr Cardiol (2012) 0.86
Comparison of information obtained by operative note abstraction with that recorded on a standardized data collection form. Surgery (2003) 0.85
A questionnaire-based survey on the prescription of non-steroidal anti-inflammatory drugs by physicians in East Asian countries in 2007. Digestion (2009) 0.85
Stage 3B Coats disease in a premature and low-birth-weight infant. Chin Med J (Engl) (2012) 0.85
Construction of robust enzyme nanocapsules for effective organophosphate decontamination, detoxification, and protection. Adv Mater (2013) 0.85
Psychological and physical abuse among pregnant women in a Medicaid-sponsored prenatal program. Public Health Nurs (2010) 0.85
Thymosin alpha 1 improves severe acute pancreatitis in rats via regulation of peripheral T cell number and cytokine serum level. J Gastroenterol Hepatol (2007) 0.85
Anoctamin 1 calcium-activated chloride channel downregulates estrogen production in mouse ovarian granulosa cells. Endocrinology (2014) 0.84
Self-assembled encapsulation systems with pH tunable release property based on reversible covalent bond. Chem Commun (Camb) (2010) 0.83
Clean STD-NMR spectrum for improved detection of ligand-protein interactions at low concentration of protein. Magn Reson Chem (2010) 0.82
MicroRNA profiling using µParaflo microfluidic array technology. Methods Mol Biol (2012) 0.82
Evaluation of therapeutic effect and cytokine change during transplacental Digoxin treatment for fetal heart failure associated with fetal tachycardia, a case-control study. Int J Cardiol (2013) 0.82
A questionnaire-based survey on the diagnosis and management of inflammatory bowel disease in East Asian countries in 2012. Digestion (2014) 0.82
Genetic variations of DNA repair genes and their prognostic significance in patients with acute myeloid leukemia. Int J Cancer (2011) 0.82
Who participates in state sponsored Medicaid enhanced prenatal services? Matern Child Health J (2008) 0.82
Roles of TGF-β/Smad signaling pathway in pathogenesis and development of gluteal muscle contracture. Connect Tissue Res (2014) 0.81
[Effects of autologous mesenchymal stem cells transfected with heme oxygenase-1 gene transplantation on ischemic Swine hearts]. Zhonghua Xin Xue Guan Bing Za Zhi (2009) 0.81
Genetic diversity analysis of five cattle breeds native to China using microsatellites. J Genet (2005) 0.81
Growth inhibitory effect of the ternary complex factor Net on human pancreatic carcinoma cell lines. Tohoku J Exp Med (2008) 0.80
Survey of clinical practice for irritable bowel syndrome in East asian countries. Digestion (2015) 0.80
Medicaid home visitation and maternal and infant healthcare utilization. Am J Prev Med (2013) 0.80
Gemcitabine, oxaliplatin and dexamethasone as salvage treatment for elderly patients with refractory and relapsed peripheral T-cell lymphoma. Leuk Lymphoma (2012) 0.80
Predictors of 2010-2011 Michigan Medicaid Beneficiary Adverse E-Code Health Care Encounters. J Patient Saf (2015) 0.80
Motor training increases the stability of activation patterns in the primary motor cortex. PLoS One (2013) 0.79
Intensified monitoring of circadian blood pressure and heart rate before and after intravitreous injection of bevacizumab: preliminary findings of a pilot study. Int Ophthalmol (2008) 0.79
A cross-validation study to select a classification procedure for clinical diagnosis based on proteomic mass spectrometry. Stat Appl Genet Mol Biol (2008) 0.79
[A preliminary study of endoscopic ultrasonography in the preoperative staging of early gastric carcinoma]. Zhonghua Zhong Liu Za Zhi (2003) 0.79
Qualitative and quantitative analysis of peptide microarray binding experiments using SVM-PEPARRAY. Methods Mol Biol (2009) 0.79
Arcuate Src activation-induced phosphorylation of NR2B NMDA subunit contributes to inflammatory pain in rats. J Neurophysiol (2012) 0.79
Combination therapy for scalp angiosarcoma using bevacizumab and chemotherapy: a case report and review of literature. Chin J Cancer Res (2013) 0.79
Differential expression of vascular endothelial growth factor-a isoforms in neovascular age-related macular degeneration. Retina (2015) 0.79
A Class-Information-Based Sparse Component Analysis Method to Identify Differentially Expressed Genes on RNA-Seq Data. IEEE/ACM Trans Comput Biol Bioinform (2016) 0.79
Xenoreactive CD4+ memory T cells resist inhibition by anti-CD44 mAb and reject islet grafts via a Th2-dependent pathway. Xenotransplantation (2011) 0.78
Brassinosteroid negatively regulates jasmonate inhibition of root growth in Arabidopsis. Plant Signal Behav (2010) 0.78
Improving the secretory production of the heterologous protein in Pichia pastoris by focusing on protein folding. Appl Biochem Biotechnol (2014) 0.78
Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana. J Biol Chem (2013) 0.78
The role of unilateral adrenalectomy in corticotropin-independent bilateral adrenocortical hyperplasias. World J Surg (2013) 0.78
Protective effects of indomethacin and dexamethasone in a goat model with intrauterine balloon aortic valvuloplasty. J Biomed Sci (2012) 0.78
Cobratoxin inhibits pain-evoked discharge of neurons in thalamic parafascicular nucleus in rats: involvement of cholinergic and serotonergic systems. Toxicon (2009) 0.78
A questionnaire-based survey on screening for gastric and colorectal cancer by physicians in East Asian countries in 2010. Digestion (2012) 0.78
Hybrid polymerization of vinyl and hetero-ring groups of glycidyl methacrylate resulting in thermoresponsive hyperbranched polymers displaying a wide range of lower critical solution temperatures. Chemistry (2009) 0.78
High incidence of tuberculosis infection in rheumatic diseases and impact for chemoprophylactic prevention of tuberculosis activation during biologics therapy. Clin Vaccine Immunol (2013) 0.77
Impact of intrauterine balloon aortic valvuloplasty on gestational outcome in a fetal goat model. Fetal Diagn Ther (2011) 0.77
Real-time monitoring of anticancer drug release with highly fluorescent star-conjugated copolymer as a drug carrier. Biomacromolecules (2014) 0.77
11C-CHO PET in optimization of target volume delineation and treatment regimens in postoperative radiotherapy for brain gliomas. Nucl Med Biol (2011) 0.77
[Effect of changji' an oral liquid on activated signal alterative intensity in algesthesia domain in patients with diarrhea type irritable bowel syndrome due to gan-pi disharmony]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2005) 0.77
Transplacental digoxin therapy for fetal tachyarrhythmia with multiple evaluation systems. J Matern Fetal Neonatal Med (2011) 0.77
Questionnaire-Based Survey on Diagnostic and Therapeutic Endoscopies and H. pylori Eradication for Elderly Patients in East Asian Countries. Digestion (2016) 0.76
A novel evolutionarily conserved element is a general transcriptional repressor of p21WAF¹/CIP¹. Cancer Res (2012) 0.76
Fast (4,3)D GFT-TS NMR for NOESY of small to medium-sized proteins. J Magn Reson (2007) 0.76
Enhanced NMDA receptor NR1 phosphorylation and neuronal activity in the arcuate nucleus of hypothalamus following peripheral inflammation. Acta Pharmacol Sin (2011) 0.76
[Preparation, characterization and potential application of monoclonal antibody 18A4 against AGR2]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2010) 0.76
Sequence-specific 1H-NMR assignment and determination of the secondary structure of hainantoxin-III from the spider Ornithoctonus hainana. Protein Pept Lett (2013) 0.76
Efficacy of oral Etoposide in pretreated metastatic breast cancer: a multicenter phase 2 study. Medicine (Baltimore) (2015) 0.76
Interactions between XIAP associated factor 1 and a nuclear co-activator, CBP, in colon cancer cells. Digestion (2008) 0.76
Net expression inhibits the growth of pancreatic ductal adenocarcinoma cell PL45 in vitro and in vivo. PLoS One (2013) 0.76
Transplacental digoxin therapy for fetal atrial flutter with hydrops fetalis. World J Pediatr (2011) 0.76
[Correlation of cell cycle alteration to SOCS-1 gene demethylation induced by arsenic trioxide in myeloma cell lines]. Ai Zheng (2008) 0.76
Combination of monoclonal antibodies with DST inhibits accelerated rejection mediated by memory T cells to induce long-lived heart allograft acceptance in mice. Immunol Lett (2011) 0.76
Induction of anterior gradient 2 (AGR2) plays a key role in insulin-like growth factor-1 (IGF-1)-induced breast cancer cell proliferation and migration. Med Oncol (2015) 0.75
Temperature-induced emission enhancement of star conjugated copolymers with poly(2-(dimethylamino)ethyl methacrylate) coronas for detection of bacteria. Biomacromolecules (2013) 0.75
8-Chloroadenosine 3',5'-monophosphate induces cell cycle arrest and apoptosis in multiple myeloma cells through multiple mechanisms. Oncol Lett (2012) 0.75
The impact of Clostridum difficile on surgical rate among ulcerative colitis patients: A systemic review and meta-analysis. Saudi J Gastroenterol (2015) 0.75
Web-based design of peptide microarrays using microPepArray Pro. Methods Mol Biol (2009) 0.75
Role of pigment epithelium-derived factor on proliferation and migration of choroidal capillary endothelium induced by vascular endothelial growth factor in vitro. Chin Med J (Engl) (2007) 0.75
Consensus of the present and prospects on endoscopic diagnosis and treatment in East asian countries. Diagn Ther Endosc (2012) 0.75
Effects of heme oxygenase-1 gene modulated mesenchymal stem cells on vasculogenesis in ischemic swine hearts. Chin Med J (Engl) (2011) 0.75