Published in Biosystems on June 03, 2013
Fingerprints of a message: integrating positional information on the transcriptome. Front Cell Dev Biol (2014) 0.79
Towards standardization of RNA quality assessment using user-independent classifiers of microcapillary electrophoresis traces. Nucleic Acids Res (2005) 7.63
Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol (2004) 7.17
Peginterferon alfa-2b and ribavirin for 12 vs. 24 weeks in HCV genotype 2 or 3. N Engl J Med (2005) 4.79
Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet (2010) 4.65
Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia. N Engl J Med (2012) 3.20
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis. Nat Genet (2010) 3.15
Pegylated interferon alpha-2b as monotherapy or in combination with ribavirin in chronic hepatitis delta. Hepatology (2006) 3.14
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms. Gastroenterology (2007) 2.32
Individualized treatment duration for hepatitis C genotype 1 patients: A randomized controlled trial. Hepatology (2008) 2.28
Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: a meta-analysis of individual patient data. Gastroenterology (2006) 2.26
Peginterferon alfa-2b and ribavirin in patients with hepatitis C virus and decompensated cirrhosis: a controlled study. J Hepatol (2006) 2.09
The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res (2007) 2.07
Variation in genes encoding for interferon λ-3 and λ-4 in the prediction of HCV-1 treatment-induced viral clearance. Liver Int (2013) 2.07
An association study between epicardial fat thickness and cognitive impairment in the elderly. Am J Physiol Heart Circ Physiol (2014) 2.06
MicroRNA-29 in aortic dilation: implications for aneurysm formation. Circ Res (2011) 2.01
Randomized controlled trial of botulinum toxin versus laparoscopic heller myotomy for esophageal achalasia. Ann Surg (2004) 1.98
Deciphering cellular states of innate tumor drug responses. Genome Biol (2006) 1.83
Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med (2011) 1.78
The road from systems biology to systems medicine. Pediatr Res (2013) 1.70
Aldosterone activates NF-kappaB in the collecting duct. J Am Soc Nephrol (2008) 1.67
Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia. Proc Natl Acad Sci U S A (2005) 1.67
Revolutionizing medicine in the 21st century through systems approaches. Biotechnol J (2012) 1.60
Experts' opinions on the role of liver biopsy in HCV infection: a Delphi survey by the Italian Association of Hospital Gastroenterologists (A.I.G.O.). J Hepatol (2005) 1.55
Diagnosis of liver nodules observed in chronic liver disease patients during ultrasound screening for early detection of hepatocellular carcinoma. Am J Gastroenterol (2002) 1.51
Radiofrequency thermal ablation vs. percutaneous ethanol injection for small hepatocellular carcinoma in cirrhosis: meta-analysis of randomized controlled trials. Am J Gastroenterol (2009) 1.50
Determinants of relapse after a short (12 weeks) course of antiviral therapy and re-treatment efficacy of a prolonged course in patients with chronic hepatitis C virus genotype 2 or 3 infection. Hepatology (2009) 1.49
Erythrocyte-mediated delivery of dexamethasone in patients with mild-to-moderate ulcerative colitis, refractory to mesalamine: a randomized, controlled study. Am J Gastroenterol (2008) 1.47
Mirna expression profiles identify drivers in colorectal and pancreatic cancers. PLoS One (2012) 1.47
Adherence to American Association for the Study of Liver Diseases guidelines for the management of hepatocellular carcinoma: results of an Italian field practice multicenter study. Future Oncol (2013) 1.46
An in vitro model of hepatitis C virus genotype 3a-associated triglycerides accumulation. J Hepatol (2005) 1.46
Coarse nodular US pattern in hepatic cirrhosis: risk for hepatocellular carcinoma. Radiology (2003) 1.45
The intelligent, painless, "germ-free" colonoscopy: A Columbus' egg for increasing population adherence to colorectal cancer screening? Dig Liver Dis (2010) 1.41
The Human Anatomic Gene Expression Library (H-ANGEL), the H-Inv integrative display of human gene expression across disparate technologies and platforms. Nucleic Acids Res (2005) 1.39
HNF1alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP-1 and carbohydrate-response element-binding protein (ChREBP) activation. J Biol Chem (2007) 1.36
Aberrant DNA methylation in non-neoplastic gastric mucosa of H. Pylori infected patients and effect of eradication. Am J Gastroenterol (2007) 1.28
Application of 'omics technologies to biomarker discovery in inflammatory lung diseases. Eur Respir J (2013) 1.19
A phytoestrogen-rich diet increases energy expenditure and decreases adiposity in mice. Environ Health Perspect (2007) 1.19
A modified fast-track program for pancreatic surgery: a prospective single-center experience. Langenbecks Arch Surg (2010) 1.19
Dietary phytoestrogens activate AMP-activated protein kinase with improvement in lipid and glucose metabolism. Diabetes (2008) 1.17
'The 39 steps' in gene expression profiling: critical issues and proposed best practices for microarray experiments. Drug Discov Today (2005) 1.15
Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes. Hepatology (2008) 1.13
Liver diseases and aging: friends or foes? Aging Cell (2013) 1.12
Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014. Am J Respir Crit Care Med (2015) 1.12
Variants of CARD15 are associated with an aggressive clinical course of Crohn's disease--an IG-IBD study. Am J Gastroenterol (2005) 1.11
Associations between genetic polymorphisms in IL-33, IL1R1 and risk for inflammatory bowel disease. PLoS One (2013) 1.10
Dual effects of hypertonicity on aquaporin-2 expression in cultured renal collecting duct principal cells. J Am Soc Nephrol (2005) 1.08
Fatal systemic venous air embolism during endoscopic retrograde cholangiopancreatography. Adv Anat Pathol (2009) 1.08
High doses of interferon in combination with ribavirin are more effective than the standard regimen in patients with HCV genotype 1 chronic hepatitis. J Hepatol (2002) 1.08
Bridging the gap between systems biology and medicine. Genome Med (2009) 1.07
Mutations in B9D1 and MKS1 cause mild Joubert syndrome: expanding the genetic overlap with the lethal ciliopathy Meckel syndrome. Orphanet J Rare Dis (2014) 1.07
Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma. PLoS One (2013) 1.06
Changes in miR-143 and miR-21 expression and clinicopathological correlations in pancreatic cancers. Pancreas (2012) 1.06
Cancer risk associated with STK11/LKB1 germline mutations in Peutz-Jeghers syndrome patients: results of an Italian multicenter study. Dig Liver Dis (2013) 1.06
Old age and steatohepatitis: a dangerous liaison? Hepatology (2013) 1.06
The beta-catenin pathway is activated in focal nodular hyperplasia but not in cirrhotic FNH-like nodules. J Hepatol (2008) 1.06
Outcome of chronic delta hepatitis in Italy: a long-term cohort study. J Hepatol (2010) 1.06
Protein subnetwork markers improve prediction of cancer outcome. Mol Syst Biol (2007) 1.05
Targeting chromatin remodelers to treat hepatocellular carcinoma. Hepatology (2013) 1.05
mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart. Aging Cell (2011) 1.04
Hepatitis delta virus inhibits alpha interferon signaling. Hepatology (2009) 1.03
Non invasive evaluation of liver fibrosis in paediatric patients with nonalcoholic steatohepatitis. World J Gastroenterol (2006) 1.03
Italian consensus guidelines for chronic pancreatitis. Dig Liver Dis (2010) 1.02
Clock genes and clock-controlled genes in the regulation of metabolic rhythms. Chronobiol Int (2012) 1.02
High RAD51 mRNA expression characterize estrogen receptor-positive/progesteron receptor-negative breast cancer and is associated with patient's outcome. Int J Cancer (2010) 1.01
Investigation of multiple susceptibility loci for inflammatory bowel disease in an Italian cohort of patients. PLoS One (2011) 1.00
Lamivudine/interferon combination therapy in anti-HBe positive chronic hepatitis B patients: a controlled pilot study. J Hepatol (2002) 0.99
Promoter methylation correlates with reduced NDRG2 expression in advanced colon tumour. BMC Med Genomics (2009) 0.99
Computational disease modeling - fact or fiction? BMC Syst Biol (2009) 0.98
Mutation analysis of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the cationic trypsinogen (PRSS1) gene, and the serine protease inhibitor, Kazal type 1 (SPINK1) gene in patients with alcoholic chronic pancreatitis. Eur J Hum Genet (2003) 0.98
Redox homeostasis and epigenetics in non-alcoholic fatty liver disease (NAFLD). Curr Pharm Des (2013) 0.97
The risk of upper gastrointestinal bleeding in elderly users of aspirin and other non-steroidal anti-inflammatory drugs: the role of gastroprotective drugs. Aging Clin Exp Res (2003) 0.97
Usefulness of the comprehensive geriatric assessment in older patients with upper gastrointestinal bleeding: a two-year follow-up study. Dig Dis (2007) 0.97
A functional and regulatory network associated with PIP expression in human breast cancer. PLoS One (2009) 0.96
The circadian clock circuitry and the AHR signaling pathway in physiology and pathology. Biochem Pharmacol (2013) 0.96
Mitochondria-cytoskeleton interaction: distribution of β-tubulins in cardiomyocytes and HL-1 cells. Biochim Biophys Acta (2011) 0.96
Genetic susceptibility to pancreatic cancer and its functional characterisation: the PANcreatic Disease ReseArch (PANDoRA) consortium. Dig Liver Dis (2012) 0.95
Variants at the 3p21 locus influence susceptibility and phenotype both in adults and early-onset patients with inflammatory bowel disease. Inflamm Bowel Dis (2010) 0.95
Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets. Hepatology (2011) 0.95
Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease. Aging (Albany NY) (2014) 0.95
Clinical features of reflux esophagitis in older people: a study of 840 consecutive patients. J Am Geriatr Soc (2006) 0.94
Scale relativity theory and integrative systems biology: 2. Macroscopic quantum-type mechanics. Prog Biophys Mol Biol (2007) 0.94
DNA methyltransferases 1 and 3b expression in Huh-7 cells expressing HCV core protein of different genotypes. Dig Dis Sci (2012) 0.94
Altered expression of the clock gene machinery in kidney cancer patients. Biomed Pharmacother (2011) 0.94
The RHNumtS compilation: features and bioinformatics approaches to locate and quantify Human NumtS. BMC Genomics (2008) 0.93
Evaluating the role of the genetic variations of PTPN22, NFKB1, and FcGRIIIA genes in inflammatory bowel disease: a meta-analysis. Inflamm Bowel Dis (2007) 0.93
Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar. J Allergy Clin Immunol (2012) 0.93
Systems biologists seek fuller integration of systems biology approaches in new cancer research programs. Cancer Res (2009) 0.92
Hypermethylated levels of E-cadherin promoter in Huh-7 cells expressing the HCV core protein. Virus Res (2011) 0.92
Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes. Lab Invest (2007) 0.92
Growth factors, nutrient signaling, and cardiovascular aging. Circ Res (2012) 0.91