Flavio Curnis

Author PubWeight™ 24.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function. Eur Heart J 2007 1.81
2 The neovasculature homing motif NGR: more than meets the eye. Blood 2008 1.46
3 Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha. Clin Cancer Res 2006 1.37
4 Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif. J Biol Chem 2002 1.22
5 Targeted drug delivery and penetration into solid tumors. Med Res Rev 2011 1.19
6 Targeting TNF-α to neoangiogenic vessels enhances lymphocyte infiltration in tumors and increases the therapeutic potential of immunotherapy. J Immunol 2012 1.17
7 Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin. J Biol Chem 2008 1.03
8 Isoaspartate-dependent molecular switches for integrin-ligand recognition. J Cell Sci 2011 1.00
9 Chromogranin A protects vessels against tumor necrosis factor alpha-induced vascular leakage. FASEB J 2004 0.99
10 Tumor vasculature targeting through NGR peptide-based drug delivery systems. Curr Pharm Biotechnol 2011 0.97
11 A new chromogranin A-dependent angiogenic switch activated by thrombin. Blood 2012 0.96
12 Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma. J Control Release 2010 0.96
13 Crucial role for interferon gamma in the synergism between tumor vasculature-targeted tumor necrosis factor alpha (NGR-TNF) and doxorubicin. Cancer Res 2004 0.93
14 Critical role of indoleamine 2,3-dioxygenase in tumor resistance to repeated treatments with targeted IFNgamma. Mol Cancer Ther 2008 0.92
15 Chromogranin A restricts drug penetration and limits the ability of NGR-TNF to enhance chemotherapeutic efficacy. Cancer Res 2011 0.91
16 Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif. Mol Immunol 2005 0.90
17 Peptide-mediated targeting of cytokines to tumor vasculature: the NGR-hTNF example. BioDrugs 2013 0.88
18 Chromogranin A expression in neoplastic cells affects tumor growth and morphogenesis in mouse models. Cancer Res 2002 0.86
19 Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3. Angew Chem Int Ed Engl 2013 0.85
20 Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings. J Control Release 2013 0.84
21 Synergistic damage of tumor vessels with ultra low-dose endothelial-monocyte activating polypeptide-II and neovasculature-targeted tumor necrosis factor-alpha. Cancer Res 2008 0.84
22 Cleavage of chromogranin A N-terminal domain by plasmin provides a new mechanism for regulating cell adhesion. J Biol Chem 2002 0.80
23 Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling. J Biol Chem 2013 0.79
24 Role of vasostatin-1 C-terminal region in fibroblast cell adhesion. Cell Mol Life Sci 2010 0.77
25 NGR-TNF engineering with an N-terminal serine reduces degradation and post-translational modifications and improves its tumor targeting activity. Mol Pharm 2020 0.75