David R Plas

Author PubWeight™ 54.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 2005 11.19
2 Akt stimulates aerobic glycolysis in cancer cells. Cancer Res 2004 9.35
3 The CD28 signaling pathway regulates glucose metabolism. Immunity 2002 6.65
4 Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. Mol Cell Biol 2003 3.84
5 VHL-regulated MiR-204 suppresses tumor growth through inhibition of LC3B-mediated autophagy in renal clear cell carcinoma. Cancer Cell 2012 3.01
6 Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. FASEB J 2004 1.79
7 Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription. J Biol Chem 2002 1.70
8 IKKβ and NF-κB transcription govern lymphoma cell survival through AKT-induced plasma membrane trafficking of GLUT1. Cancer Res 2011 1.67
9 Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition. Cancer Res 2011 1.53
10 Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis. Cell 2013 1.44
11 Identification of Akt-selective cytotoxic compounds that enhance cytotoxic responses to rapamycin. Cancer Biol Ther 2010 1.39
12 Bcl-x(L) and Akt cooperate to promote leukemogenesis in vivo. Oncogene 2003 1.30
13 Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis. Cancer Res 2004 1.30
14 FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1. J Biol Chem 2010 1.29
15 A major role for Bim in regulatory T cell homeostasis. J Immunol 2010 1.15
16 Requirement for ribosomal protein S6 kinase 1 to mediate glycolysis and apoptosis resistance induced by Pten deficiency. Proc Natl Acad Sci U S A 2011 1.09
17 Balancing biosynthesis and bioenergetics: metabolic programs in oncogenesis. Endocr Relat Cancer 2010 1.07
18 IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels. Front Immunol 2013 0.96
19 Alternatively spliced tissue factor contributes to tumor spread and activation of coagulation in pancreatic ductal adenocarcinoma. Int J Cancer 2013 0.91
20 Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells. J Immunol 2011 0.90
21 Interleukin-6 receptor enhances early colonization of the murine omentum by upregulation of a mannose family receptor, LY75, in ovarian tumor cells. Clin Exp Metastasis 2011 0.83
22 Not all autophagy is equal. Autophagy 2012 0.81
23 S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance. J Clin Invest 2016 0.77
24 Targeting bioenergetics to enhance cancer chemotherapy: mitochondria SLP into apoptosis. Cancer Biol Ther 2009 0.77