Published in Lab Invest on June 24, 2013
A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway. J Biol Chem (2014) 0.85
Colonic miRNA expression/secretion, regulated by intestinal epithelial PepT1, plays an important role in cell-to-cell communication during colitis. PLoS One (2014) 0.82
MicroRNA-193a-3p Reduces Intestinal Inflammation in Response to Microbiota via Down-regulation of Colonic PepT1. J Biol Chem (2015) 0.78
USP18 Sensitivity of Peptide Transporters PEPT1 and PEPT2. PLoS One (2015) 0.76
PepT1 Expression Helps Maintain Intestinal Homeostasis by Mediating the Differential Expression of miRNAs along the Crypt-Villus Axis. Sci Rep (2016) 0.75
Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model. Cell Mol Gastroenterol Hepatol (2016) 0.75
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity (2009) 6.86
The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. Nat Immunol (2011) 5.22
Hydrothermal syntheses, crystal structures, and characteristics of a series of Cd-btx coordination polymers (btx = 1,4-Bis(triazol-1-ylmethyl)benzene). Inorg Chem (2004) 2.73
Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells. Cancer Res (2007) 2.50
A subpopulation of nociceptors specifically linked to itch. Nat Neurosci (2012) 2.41
Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis. PLoS One (2009) 2.35
Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology (2005) 2.03
hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells. Gastroenterology (2004) 1.91
Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor. Cancer Res (2008) 1.67
Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines. Nat Mater (2010) 1.67
Retracted Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism. Cell (2011) 1.62
Homeostatic scaling requires group I mGluR activation mediated by Homer1a. Neuron (2010) 1.59
Colonic leptin: source of a novel proinflammatory cytokine involved in IBD. FASEB J (2004) 1.58
Dextran sodium sulfate (DSS) induces colitis in mice by forming nano-lipocomplexes with medium-chain-length fatty acids in the colon. PLoS One (2012) 1.56
Modeling the soil water retention curves of soil-gravel mixtures with regression method on the Loess Plateau of China. PLoS One (2013) 1.53
A2B adenosine receptor gene deletion attenuates murine colitis. Gastroenterology (2008) 1.49
Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism. J Neurosci (2009) 1.47
MR imaging of acute pancreatitis: correlation of abdominal wall edema with severity scores. Eur J Radiol (2012) 1.47
Interleukin-1 receptor signaling protects mice from lethal intestinal damage caused by the attaching and effacing pathogen Citrobacter rodentium. Infect Immun (2008) 1.42
IL-6 induces NF-kappa B activation in the intestinal epithelia. J Immunol (2003) 1.42
Hysteretic adsorption and desorption of hydrogen by nanoporous metal-organic frameworks. Science (2004) 1.41
3D coordination framework with uncommon two-fold interpenetrated {3(3)5(9)6(3)}-lcy net and coordinated anion exchange. Chemistry (2009) 1.40
Synaptic activity-induced conversion of intronic to exonic sequence in Homer 1 immediate early gene expression. J Neurosci (2002) 1.40
Shanthi V. Sitaraman, MD, PhD: physician, scientist, educator, and humanitarian. Gastroenterology (2011) 1.39
Prohibitin protects against oxidative stress in intestinal epithelial cells. FASEB J (2006) 1.39
A novel shredder for municipal solid waste (MSW): influence of feed moisture on breakage performance. Bioresour Technol (2010) 1.38
TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism. Am J Physiol Gastrointest Liver Physiol (2003) 1.38
MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus. BMC Neurosci (2012) 1.35
All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Kruppel-like factor 5. FEBS Lett (2004) 1.35
Expression profile of microRNAs in rat hippocampus following lithium-pilocarpine-induced status epilepticus. Neurosci Lett (2010) 1.34
Rheb1 is required for mTORC1 and myelination in postnatal brain development. Dev Cell (2011) 1.31
Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis. Am J Physiol Gastrointest Liver Physiol (2009) 1.31
Drug-loaded nanoparticles targeted to the colon with polysaccharide hydrogel reduce colitis in a mouse model. Gastroenterology (2009) 1.29
Prohibitin inhibits tumor necrosis factor alpha-induced nuclear factor-kappa B nuclear translocation via the novel mechanism of decreasing importin alpha3 expression. Mol Biol Cell (2009) 1.28
Kruppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells. Nucleic Acids Res (2006) 1.28
Poly[[μ-1,4-bis-(imidazol-1-ylmeth-yl)benzene]bis-(μ(4)-cyclo-hexane-1,4-dicarboxyl-ato)dinickel(II)]. Acta Crystallogr Sect E Struct Rep Online (2009) 1.26
Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis. J Immunol (2006) 1.25
Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission. J Neurosci (2013) 1.24
CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice. J Clin Invest (2011) 1.23
The adenosine 2b receptor is recruited to the plasma membrane and associates with E3KARP and Ezrin upon agonist stimulation. J Biol Chem (2002) 1.20
Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures. Alcohol Clin Exp Res (2012) 1.19
Characterization of the human intestinal CD98 promoter and its regulation by interferon-gamma. Am J Physiol Gastrointest Liver Physiol (2006) 1.16
MicroRNAs determine human intestinal epithelial cell fate. Differentiation (2010) 1.16
Prohibitin is a novel regulator of antioxidant response that attenuates colonic inflammation in mice. Gastroenterology (2009) 1.15
Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons. Mol Cell Neurosci (2002) 1.15
Mutation of Drosophila homer disrupts control of locomotor activity and behavioral plasticity. J Neurosci (2002) 1.15
Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway. J Cell Sci (2004) 1.15
Exceptional behavior over the whole adsorption-storage-delivery cycle for NO in porous metal organic frameworks. J Am Chem Soc (2008) 1.14
The RNA binding protein CsrA is a pleiotropic regulator of the locus of enterocyte effacement pathogenicity island of enteropathogenic Escherichia coli. Infect Immun (2009) 1.14
Impaired consciousness in epilepsy investigated by a prospective responsiveness in epilepsy scale (RES). Epilepsia (2011) 1.14
Preso1 dynamically regulates group I metabotropic glutamate receptors. Nat Neurosci (2012) 1.12
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology (2007) 1.12
MicroRNA-7 modulates CD98 expression during intestinal epithelial cell differentiation. J Biol Chem (2009) 1.12
Microbiota modulate host gene expression via microRNAs. PLoS One (2011) 1.12
Functional TNFα gene silencing mediated by polyethyleneimine/TNFα siRNA nanocomplexes in inflamed colon. Biomaterials (2011) 1.11
Polarized fibronectin secretion induced by adenosine regulates bacterial-epithelial interaction in human intestinal epithelial cells. Biochem J (2004) 1.11
Interleukin-6 induces keratin expression in intestinal epithelial cells: potential role of keratin-8 in interleukin-6-induced barrier function alterations. J Biol Chem (2007) 1.10
The PepT1-NOD2 signaling pathway aggravates induced colitis in mice. Gastroenterology (2011) 1.07
Luminal leptin enhances CD147/MCT-1-mediated uptake of butyrate in the human intestinal cell line Caco2-BBE. J Biol Chem (2002) 1.07
Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. J Biol Chem (2004) 1.06
Dextran sodium sulfate inhibits the activities of both polymerase and reverse transcriptase: lithium chloride purification, a rapid and efficient technique to purify RNA. BMC Res Notes (2013) 1.05
PepT1 mediates transport of the proinflammatory bacterial tripeptide L-Ala-{gamma}-D-Glu-meso-DAP in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol (2010) 1.05
Role of microRNAs in endothelial inflammation and senescence. Mol Biol Rep (2011) 1.04
MicroRNAs expression in ox-LDL treated HUVECs: MiR-365 modulates apoptosis and Bcl-2 expression. Biochem Biophys Res Commun (2011) 1.03
Matrix metalloproteinase-9 functions as a tumor suppressor in colitis-associated cancer. Cancer Res (2010) 1.03
Acute hydrocephalus following heroin induced leukoencephalopathy. Neurol Sci (2012) 1.02
Activation of epithelial CD98 glycoprotein perpetuates colonic inflammation. Lab Invest (2005) 1.02
A prolyl-isomerase mediates dopamine-dependent plasticity and cocaine motor sensitization. Cell (2013) 1.01
Possibilities and potential roles of estrogen in the pathogenesis of proliferation hemangiomas formation. Med Hypotheses (2008) 1.01
Matrix metalloproteinase-9 regulates MUC-2 expression through its effect on goblet cell differentiation. Gastroenterology (2007) 1.01
TGF-beta down-regulates IL-6 signaling in intestinal epithelial cells: critical role of SMAD-2. FASEB J (2003) 1.01
Epithelial-derived fibronectin expression, signaling, and function in intestinal inflammation. J Biol Chem (2007) 1.00
NO-releasing zeolites and their antithrombotic properties. J Am Chem Soc (2006) 1.00
ADAM-15 inhibits wound healing in human intestinal epithelial cell monolayers. Am J Physiol Gastrointest Liver Physiol (2004) 1.00
MicroRNA let-7c inhibits Bcl-xl expression and regulates ox-LDL-induced endothelial apoptosis. BMB Rep (2012) 0.99
Nanoparticle-based therapeutic delivery of prohibitin to the colonic epithelial cells ameliorates acute murine colitis. Inflamm Bowel Dis (2010) 0.99
Pathogenic bacteria induce colonic PepT1 expression: an implication in host defense response. Gastroenterology (2009) 0.98
hPepT1 mediates bacterial tripeptide fMLP uptake in human monocytes. Lab Invest (2006) 0.98
Adenosine 2B receptors (A(2B)AR) on enteric neurons regulate murine distal colonic motility. FASEB J (2009) 0.98
Butyrate transcriptionally enhances peptide transporter PepT1 expression and activity. PLoS One (2008) 0.98
SRF binding to SRE 6.9 in the Arc promoter is essential for LTD in cultured Purkinje cells. Nat Neurosci (2010) 0.98
Leptin transcriptionally enhances peptide transporter (hPepT1) expression and activity via the cAMP-response element-binding protein and Cdx2 transcription factors. J Biol Chem (2006) 0.97
The oligopeptide transporter hPepT1: gateway to the innate immune response. Lab Invest (2006) 0.97
Intestinal epithelial CD98: an oligomeric and multifunctional protein. Biochim Biophys Acta (2008) 0.97
Mannosylated bioreducible nanoparticle-mediated macrophage-specific TNF-α RNA interference for IBD therapy. Biomaterials (2013) 0.97
Adenosine 2B receptor expression is post-transcriptionally regulated by microRNA. J Biol Chem (2010) 0.97
Agonist-induced polarized trafficking and surface expression of the adenosine 2b receptor in intestinal epithelial cells: role of SNARE proteins. Am J Physiol Gastrointest Liver Physiol (2004) 0.96
A prospective study of loss of consciousness in epilepsy using virtual reality driving simulation and other video games. Epilepsy Behav (2010) 0.96
PepT1-mediated fMLP transport induces intestinal inflammation in vivo. Am J Physiol Cell Physiol (2002) 0.95
Testing for the presence of magnetite in the upper-beak skin of homing pigeons. Biometals (2006) 0.94
Magnetic resonance imaging versus Acute Physiology And Chronic Healthy Evaluation II score in predicting the severity of acute pancreatitis. Eur J Radiol (2010) 0.94
The role and pathophysiological relevance of membrane transporter PepT1 in intestinal inflammation and inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol (2011) 0.92