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Quantification of walking-based physical activity and sedentary time in individuals with Rett syndrome. Dev Med Child Neurol (2017) 1.39

An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy. Mol Cell Biol (2013) 1.23

The role of alterations in mitochondrial dynamics and PGC-1α over-expression in fast muscle atrophy following hindlimb unloading. J Physiol (2015) 1.12

CrossTalk opposing view: The dominant mechanism causing disuse muscle atrophy is proteolysis. J Physiol (2014) 1.07

MicroRNAs in metabolism. Acta Physiol (Oxf) (2016) 0.97

Dysregulation of skeletal muscle protein metabolism by alcohol. Am J Physiol Endocrinol Metab (2015) 0.95

A map of the phosphoproteomic alterations that occur after a bout of maximal-intensity contractions. J Physiol (2017) 0.89

The molecular basis for load-induced skeletal muscle hypertrophy. Calcif Tissue Int (2014) 0.88

p53 and ATF4 mediate distinct and additive pathways to skeletal muscle atrophy during limb immobilization. Am J Physiol Endocrinol Metab (2014) 0.87

Characterization of adipocytes derived from fibro/adipogenic progenitors resident in human skeletal muscle. Cell Death Dis (2015) 0.87

Omega-3 Fatty Acids and Skeletal Muscle Health. Mar Drugs (2015) 0.86

Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy. Am J Physiol Endocrinol Metab (2014) 0.84

Connecting Myokines and Metabolism. Endocrinol Metab (Seoul) (2015) 0.82

Curcumin counteracts loss of force and atrophy of hindlimb unloaded rat soleus by hampering neuronal nitric oxide synthase untethering from sarcolemma. J Physiol (2014) 0.81

Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis. Aging (Albany NY) (2016) 0.80

Changes in REDD1, REDD2, and atrogene mRNA expression are prevented in skeletal muscle fixed in a stretched position during hindlimb immobilization. Physiol Rep (2014) 0.80

Control of skeletal muscle atrophy in response to disuse: clinical/preclinical contentions and fallacies of evidence. Am J Physiol Endocrinol Metab (2016) 0.79

Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas. Dis Model Mech (2016) 0.79

The role of mTOR signaling in the regulation of protein synthesis and muscle mass during immobilization in mice. Dis Model Mech (2015) 0.78

A reduced activity model: a relevant tool for the study of ageing muscle. Biogerontology (2015) 0.77

Stable atrogin-1 (Fbxo32) and MuRF1 (Trim63) gene expression is involved in the protective mechanism in soleus muscle of hibernating Daurian ground squirrels (Spermophilus dauricus). Biol Open (2016) 0.77

Towards human exploration of space: the THESEUS review series on muscle and bone research priorities. NPJ Microgravity (2017) 0.77

Specialized Functional Diversity and Interactions of the Na,K-ATPase. Front Physiol (2016) 0.76

Respiratory and limb muscle dysfunction in pulmonary arterial hypertension: a role for exercise training? Pulm Circ (2015) 0.76

MicroRNA-208b progressively declines after spinal cord injury in humans and is inversely related to myostatin expression. Physiol Rep (2015) 0.76

Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation. PLoS One (2015) 0.76

Isoform-specific Na,K-ATPase alterations precede disuse-induced atrophy of rat soleus muscle. Biomed Res Int (2015) 0.76

Noninvasive imaging of in vivo MuRF1 expression during muscle atrophy. PLoS One (2014) 0.76

Slow recovery of the impaired fatigue resistance in postunloading mouse soleus muscle corresponding to decreased mitochondrial function and a compensatory increase in type I slow fibers. Am J Physiol Cell Physiol (2015) 0.76

The delayed recovery of the remobilized rat tibialis anterior muscle reflects a defect in proliferative and terminal differentiation that impairs early regenerative processes. J Cachexia Sarcopenia Muscle (2015) 0.75

Proteomic and bioinformatic analyses of spinal cord injury‑induced skeletal muscle atrophy in rats. Mol Med Rep (2016) 0.75

The Signature of MicroRNA Dysregulation in Muscle Paralyzed by Spinal Cord Injury Includes Downregulation of MicroRNAs that Target Myostatin Signaling. PLoS One (2016) 0.75

Gender-specific neuromuscular adaptations to unloading in isolated rat soleus muscles. Muscle Nerve (2016) 0.75

Abnormal feeding behaviour in spinalised rats is mediated by hypothalamus: Restorative effect of exposure to extremely low frequency magnetic field. Spinal Cord (2016) 0.75

Unexpected Fascicle Length Changes In Denervated Feline Soleus Muscle During Stance Phase Of Walking. Sci Rep (2015) 0.75

Concurrent exercise on a gravity-independent device during simulated microgravity. Med Sci Sports Exerc (2015) 0.75

Effects of high EPA and high DHA fish oils on changes in signaling associated with protein metabolism induced by hindlimb suspension in rats. Physiol Rep (2016) 0.75

Short-term, high-fat diet accelerates disuse atrophy and protein degradation in a muscle-specific manner in mice. Nutr Metab (Lond) (2015) 0.75

Stair negotiation made easier using novel interactive energy-recycling assistive stairs. PLoS One (2017) 0.75

Membrane lipid rafts disturbance in the response of rat skeletal muscle to short-term disuse. Am J Physiol Cell Physiol (2017) 0.75

A dramatic blood plasticity in hibernating and 14-day hindlimb unloading Daurian ground squirrels (Spermophilus dauricus). J Comp Physiol B (2017) 0.75

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell (1999) 32.32

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev (2002) 16.10

Identification of ubiquitin ligases required for skeletal muscle atrophy. Science (2001) 12.98

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell (2004) 11.33

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol (2001) 10.85

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell (2004) 7.60

Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J (2004) 7.02

Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling. PLoS One (2008) 3.59

Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. Am J Physiol Endocrinol Metab (2008) 3.29

Rapid disuse and denervation atrophy involve transcriptional changes similar to those of muscle wasting during systemic diseases. FASEB J (2006) 3.27

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation. J Cell Biol (2009) 3.03

Regulation of peptide-chain elongation in mammalian cells. Eur J Biochem (2002) 2.86

The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle. Cell Metab (2007) 2.84

Importance of the ATP-ubiquitin-proteasome pathway in the degradation of soluble and myofibrillar proteins in rabbit muscle extracts. J Biol Chem (1996) 2.51

Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway. J Biol Chem (2004) 2.32

Prolonged bed rest decreases skeletal muscle and whole body protein synthesis. Am J Physiol (1996) 2.26

Atrophy of the soleus muscle by hindlimb unweighting. J Appl Physiol (1985) (1990) 2.15

Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique. FASEB J (2010) 2.13

Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion. J Physiol (2008) 2.05

The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene. Am J Physiol Endocrinol Metab (2008) 2.04

Disruption of either the Nfkb1 or the Bcl3 gene inhibits skeletal muscle atrophy. J Clin Invest (2004) 2.01

HECT and RING finger families of E3 ubiquitin ligases at a glance. J Cell Sci (2012) 1.95

The influence of immobilization and stretch on protein turnover of rat skeletal muscle. J Physiol (1977) 1.94

Hsp70 overexpression inhibits NF-kappaB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy. FASEB J (2008) 1.93

Skeletal muscle proteolysis in response to short-term unloading in humans. J Appl Physiol (1985) (2008) 1.93

Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism. Biochem J (2004) 1.89

Signaling pathways perturbing muscle mass. Curr Opin Clin Nutr Metab Care (2010) 1.79

Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass. FASEB J (2004) 1.75

Skeletal muscle unweighting: spaceflight and ground-based models. J Appl Physiol (1985) (2003) 1.72

The temporal responses of protein synthesis, gene expression and cell signalling in human quadriceps muscle and patellar tendon to disuse. J Physiol (2007) 1.64

FOXO signaling is required for disuse muscle atrophy and is directly regulated by Hsp70. Am J Physiol Cell Physiol (2009) 1.64

Alterations of protein turnover underlying disuse atrophy in human skeletal muscle. J Appl Physiol (1985) (2009) 1.59

The initiation factor eIF3-f is a major target for atrogin1/MAFbx function in skeletal muscle atrophy. EMBO J (2008) 1.59

Global analysis of gene expression patterns during disuse atrophy in rat skeletal muscle. J Physiol (2003) 1.59

Invited Review: Role of insulin in translational control of protein synthesis in skeletal muscle by amino acids or exercise. J Appl Physiol (1985) (2002) 1.58

Atrophy and impaired muscle protein synthesis during prolonged inactivity and stress. J Clin Endocrinol Metab (2006) 1.56

Alterations in mRNA expression and protein products following spinal cord injury in humans. J Physiol (2007) 1.55

Catalytic activities of the 20 S proteasome, a multicatalytic proteinase complex. Arch Biochem Biophys (2000) 1.53

Coordinate activation of lysosomal, Ca 2+-activated and ATP-ubiquitin-dependent proteinases in the unweighted rat soleus muscle. Biochem J (1996) 1.52

Prolonged space flight-induced alterations in the structure and function of human skeletal muscle fibres. J Physiol (2010) 1.47

Analysis of human skeletal muscle after 48 h immobilization reveals alterations in mRNA and protein for extracellular matrix components. J Appl Physiol (1985) (2006) 1.45

Muscle sparing in muscle RING finger 1 null mice: response to synthetic glucocorticoids. J Physiol (2011) 1.41

Effects of aging on human skeletal muscle after immobilization and retraining. J Appl Physiol (1985) (2009) 1.38

mTOR signaling and the molecular adaptation to resistance exercise. Med Sci Sports Exerc (2006) 1.35

Regulation of translation factors during hindlimb unloading and denervation of skeletal muscle in rats. Am J Physiol Cell Physiol (2001) 1.29

Facts, noise and wishful thinking: muscle protein turnover in aging and human disuse atrophy. Scand J Med Sci Sports (2009) 1.25

Rapamycin inhibits the growth and muscle-sparing effects of clenbuterol. J Appl Physiol (1985) (2006) 1.21

Mechanisms of skeletal muscle atrophy. Curr Opin Rheumatol (2006) 1.21

The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb. Am J Physiol Endocrinol Metab (2012) 1.20

Isometric resistance exercise fails to counteract skeletal muscle atrophy processes during the initial stages of unloading. J Appl Physiol (1985) (2005) 1.19

Upregulation of proteasome activity in muscle RING finger 1-null mice following denervation. FASEB J (2012) 1.18

Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms. J Physiol (2011) 1.17

Identification of genes that elicit disuse muscle atrophy via the transcription factors p50 and Bcl-3. PLoS One (2011) 1.17

Functional interactions between ubiquitin E2 enzymes and TRIM proteins. Biochem J (2011) 1.16

Mechanisms regulating muscle mass during disuse atrophy and rehabilitation in humans. J Appl Physiol (1985) (2010) 1.16

Contraction-mediated mTOR, p70S6k, and ERK1/2 phosphorylation in aged skeletal muscle. J Appl Physiol (1985) (2004) 1.16

Impaired overload-induced muscle growth is associated with diminished translational signalling in aged rat fast-twitch skeletal muscle. J Physiol (2006) 1.16

Contrarily to whey and high protein diets, dietary free leucine supplementation cannot reverse the lack of recovery of muscle mass after prolonged immobilization during ageing. J Physiol (2012) 1.15

Single muscle fiber function with concurrent exercise or nutrition countermeasures during 60 days of bed rest in women. J Appl Physiol (1985) (2007) 1.15

Architectural alterations of rat hind-limb skeletal muscles immobilized at different lengths. Exp Neurol (1982) 1.15

The time course of the adaptations of human muscle proteome to bed rest and the underlying mechanisms. J Physiol (2012) 1.14

Stress-induced skeletal muscle Gadd45a expression reprograms myonuclei and causes muscle atrophy. J Biol Chem (2012) 1.13

The ubiquitin-protein ligase Nedd4 targets Notch1 in skeletal muscle and distinguishes the subset of atrophies caused by reduced muscle tension. FASEB J (2006) 1.13

Early change in skeletal muscle protein synthesis after limb immobilization of rats. J Appl Physiol Respir Environ Exerc Physiol (1979) 1.13

Temporal alterations in protein signaling cascades during recovery from muscle atrophy. Am J Physiol Cell Physiol (2003) 1.12

Muscle actin is polyubiquitinylated in vitro and in vivo and targeted for breakdown by the E3 ligase MuRF1. FASEB J (2011) 1.10

Acute alcohol intoxication increases atrogin-1 and MuRF1 mRNA without increasing proteolysis in skeletal muscle. Am J Physiol Regul Integr Comp Physiol (2008) 1.09

Effects of aging on muscle mechanical function and muscle fiber morphology during short-term immobilization and subsequent retraining. J Appl Physiol (1985) (2010) 1.08

Effects of disuse on the structure and function of skeletal muscle. Med Sci Sports Exerc (1983) 1.07

Age-related deficit in load-induced skeletal muscle growth. J Gerontol A Biol Sci Med Sci (2009) 1.07

p300 Acetyltransferase activity differentially regulates the localization and activity of the FOXO homologues in skeletal muscle. Am J Physiol Cell Physiol (2011) 1.07

Impact of resistance exercise during bed rest on skeletal muscle sarcopenia and myosin isoform distribution. J Appl Physiol (1985) (1998) 1.06

The plasticity of skeletal muscle: effects of neuromuscular activity. Exerc Sport Sci Rev (1991) 1.06

A longitudinal MRI study of muscle atrophy during lower leg immobilization following ankle fracture. J Magn Reson Imaging (2011) 1.06

Gravitational unloading effects on muscle fiber size, phenotype and myonuclear number. Adv Space Res (2002) 1.05

In vivo alterations in skeletal muscle form and function after disuse atrophy. Med Sci Sports Exerc (2009) 1.04

Mechanical loading induces the expression of a Pol I regulon at the onset of skeletal muscle hypertrophy. Am J Physiol Cell Physiol (2012) 1.03

Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice. PLoS One (2012) 1.02

Short-term bed rest impairs amino acid-induced protein anabolism in humans. J Physiol (2004) 1.02

Calpain and caspase-3 play required roles in immobilization-induced limb muscle atrophy. J Appl Physiol (1985) (2013) 1.00

Modulation of muscle atrophy, fatigue and MLC phosphorylation by MuRF1 as indicated by hindlimb suspension studies on MuRF1-KO mice. J Biomed Biotechnol (2010) 0.99

Oxidative stress, apoptosis, and proteolysis in skeletal muscle repair after unloading. Am J Physiol Cell Physiol (2010) 0.96

A cell-autonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure. Am J Physiol Endocrinol Metab (2012) 0.94

Regulation of proteolysis during reloading of the unweighted soleus muscle. Int J Biochem Cell Biol (2003) 0.92

Heterogeneous atrophy occurs within individual lower limb muscles during 60 days of bed rest. J Appl Physiol (1985) (2012) 0.92

Nuclear factor-κB signalling and transcriptional regulation in skeletal muscle atrophy. Exp Physiol (2012) 0.91

Inhibition of calpain prevents muscle weakness and disruption of sarcomere structure during hindlimb suspension. J Appl Physiol (1985) (2009) 0.87

New findings of lysosomal proteolysis in skeletal muscle. Curr Opin Clin Nutr Metab Care (2011) 0.85

The role of neural and mechanical influences in maintaining normal fast and slow muscle properties. Cells Tissues Organs (2006) 0.84

Effects of inactivity on fiber size and myonuclear number in rat soleus muscle. J Appl Physiol (1985) (2005) 0.84

The worsening of tibialis anterior muscle atrophy during recovery post-immobilization correlates with enhanced connective tissue area, proteolysis, and apoptosis. Am J Physiol Endocrinol Metab (2012) 0.84

Proteolysis activation and proteome alterations in murine skeletal muscle submitted to 1 week of hindlimb suspension. Eur J Appl Physiol (2009) 0.83

Disassociation of insulin action and Akt/FOXO signaling in skeletal muscle of older Akt-deficient mice. Am J Physiol Regul Integr Comp Physiol (2012) 0.80