Husam Ghanim

Author PubWeight™ 58.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects. Diabetes 2003 3.00
2 Evidence for a potent antiinflammatory effect of rosiglitazone. J Clin Endocrinol Metab 2004 2.36
3 Differential effects of cream, glucose, and orange juice on inflammation, endotoxin, and the expression of Toll-like receptor-4 and suppressor of cytokine signaling-3. Diabetes Care 2010 1.61
4 Testosterone concentrations in diabetic and nondiabetic obese men. Diabetes Care 2010 1.60
5 Increase in intranuclear nuclear factor kappaB and decrease in inhibitor kappaB in mononuclear cells after a mixed meal: evidence for a proinflammatory effect. Am J Clin Nutr 2004 1.57
6 Sitagliptin exerts an antinflammatory action. J Clin Endocrinol Metab 2012 1.55
7 Anti-inflammatory and profibrinolytic effect of insulin in acute ST-segment-elevation myocardial infarction. Circulation 2004 1.46
8 Insulin as an anti-inflammatory and antiatherogenic modulator. J Am Coll Cardiol 2009 1.43
9 Rosiglitazone, thiazolidinediones and atherosclerosis. Atherosclerosis 2010 1.41
10 Prolonged reactive oxygen species generation and nuclear factor-kappaB activation after a high-fat, high-carbohydrate meal in the obese. J Clin Endocrinol Metab 2007 1.38
11 Exenatide exerts a potent antiinflammatory effect. J Clin Endocrinol Metab 2011 1.37
12 Glucose ingestion induces an increase in intranuclear nuclear factor kappaB, a fall in cellular inhibitor kappaB, and an increase in tumor necrosis factor alpha messenger RNA by mononuclear cells in healthy human subjects. Metabolism 2006 1.36
13 Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations. J Clin Endocrinol Metab 2002 1.35
14 Increased plasma concentration of macrophage migration inhibitory factor (MIF) and MIF mRNA in mononuclear cells in the obese and the suppressive action of metformin. J Clin Endocrinol Metab 2004 1.34
15 Angiotensin II receptor blocker valsartan suppresses reactive oxygen species generation in leukocytes, nuclear factor-kappa B, in mononuclear cells of normal subjects: evidence of an antiinflammatory action. J Clin Endocrinol Metab 2003 1.25
16 Glucose intake induces an increase in activator protein 1 and early growth response 1 binding activities, in the expression of tissue factor and matrix metalloproteinase in mononuclear cells, and in plasma tissue factor and matrix metalloproteinase concentrations. Am J Clin Nutr 2004 1.23
17 Proinflammatory effects of glucose and anti-inflammatory effect of insulin: relevance to cardiovascular disease. Am J Cardiol 2006 1.23
18 Both lipid and protein intakes stimulate increased generation of reactive oxygen species by polymorphonuclear leukocytes and mononuclear cells. Am J Clin Nutr 2002 1.19
19 Differential effects of glucose and alcohol on reactive oxygen species generation and intranuclear nuclear factor-kappaB in mononuclear cells. Metabolism 2004 1.17
20 Insulin suppresses plasma concentration of vascular endothelial growth factor and matrix metalloproteinase-9. Diabetes Care 2003 1.16
21 Reduction in endotoxemia, oxidative and inflammatory stress, and insulin resistance after Roux-en-Y gastric bypass surgery in patients with morbid obesity and type 2 diabetes mellitus. Surgery 2011 1.12
22 Low testosterone and high C-reactive protein concentrations predict low hematocrit in type 2 diabetes. Diabetes Care 2006 1.11
23 Anti-inflammatory effects of insulin. Curr Opin Clin Nutr Metab Care 2007 1.10
24 Antioxidant activity of carvedilol in cardiovascular disease. J Hypertens 2007 1.01
25 Macronutrient intake induces oxidative and inflammatory stress: potential relevance to atherosclerosis and insulin resistance. Exp Mol Med 2010 0.96
26 Insulin increases reendothelialization and inhibits cell migration and neointimal growth after arterial injury. Arterioscler Thromb Vasc Biol 2009 0.95
27 Tumor necrosis factor-alpha inhibits insulin-induced increase in endothelial nitric oxide synthase and reduces insulin receptor content and phosphorylation in human aortic endothelial cells. Metabolism 2002 0.95
28 Testosterone concentrations in young pubertal and post-pubertal obese males. Clin Endocrinol (Oxf) 2013 0.94
29 Low estradiol concentrations in men with subnormal testosterone concentrations and type 2 diabetes. Diabetes Care 2011 0.93
30 Insulin suppresses endotoxin-induced oxidative, nitrosative, and inflammatory stress in humans. Diabetes Care 2010 0.92
31 Translocation of p47phox and activation of NADPH oxidase in mononuclear cells. Methods Mol Biol 2002 0.89
32 Resveratrol inhibits neointimal formation after arterial injury through an endothelial nitric oxide synthase-dependent mechanism. Atherosclerosis 2012 0.89
33 Insulin suppresses the expression of amyloid precursor protein, presenilins, and glycogen synthase kinase-3beta in peripheral blood mononuclear cells. J Clin Endocrinol Metab 2011 0.88
34 Increase in the mediators of asthma in obesity and obesity with type 2 diabetes: reduction with weight loss. Obesity (Silver Spring) 2013 0.87
35 Anti-inflammatory effects of insulin and the pro-inflammatory effects of glucose. Semin Thorac Cardiovasc Surg 2006 0.86
36 Flow cytometry and gene expression profiling of immune cells of the carotid plaque and peripheral blood. Atherosclerosis 2013 0.86
37 Maternal obesity and fetal programming: effects of a high-carbohydrate nutritional modification in the immediate postnatal life of female rats. Am J Physiol Endocrinol Metab 2008 0.85
38 Effect of hyperglycemia and insulin in acute coronary syndromes. Am J Cardiol 2007 0.83
39 Thiazolidinediones-improving endothelial function and potential long-term benefits on cardiovascular disease in subjects with type 2 diabetes. J Diabetes Complications 2008 0.82
40 Insulin infusion suppresses while glucose infusion induces Toll-like receptors and high-mobility group-B1 protein expression in mononuclear cells of type 1 diabetes patients. Am J Physiol Endocrinol Metab 2013 0.82
41 Susceptibility to fatty acid-induced β-cell dysfunction is enhanced in prediabetic diabetes-prone biobreeding rats: a potential link between β-cell lipotoxicity and islet inflammation. Endocrinology 2012 0.82
42 Acute myocardial infarction, hyperglycemia, and insulin. J Am Coll Cardiol 2009 0.81
43 Anti-inflammatory effects of insulin and pro-inflammatory effects of glucose: relevance to the management of acute myocardial infarction and other acute coronary syndromes. Rev Cardiovasc Med 2006 0.80
44 Effect of modified glucose-insulin-potassium on free fatty acids, matrix metalloproteinase, and myoglobin in ST-elevation myocardial infarction. Am J Cardiol 2007 0.80
45 Activation of nuclear factor-kappa B (NF-kappa B) in mononuclear cells (MNC). Methods Mol Biol 2002 0.80
46 Free fatty acid-induced insulin resistance in the obese is not prevented by rosiglitazone treatment. J Clin Endocrinol Metab 2005 0.80
47 Use of insulin to improve glycemic control in diabetes mellitus. Cardiovasc Drugs Ther 2008 0.78
48 Insulin and Alzheimer disease. Arch Neurol 2012 0.75
49 Comment on: Lassenius et al. Bacterial endotoxin activity in human serum is associated with dyslipidemia, insulin resistance, obesity, and chronic inflammation. Diabetes Care 2011;34:1809-1815. Diabetes Care 2012 0.75
50 ADJUNCT THERAPIES IN TYPE 1 DIABETES. Endocr Pract 2016 0.75
51 Insulin therapy and lipid overload in type 2 diabetes. JAMA 2008 0.75
52 Letter by Chaudhuri et al regarding article, "Differential clinical outcomes associated with hypoglycemia and hyperglycemia in acute myocardial infarction". Circulation 2010 0.75
53 Associations between dietary fiber and inflammation, hepatic function, and risk of type 2 diabetes in older men: potential mechanisms for the benefits of fiber on diabetes risk: response to wannamethee et Al. Diabetes Care 2010 0.75
54 An inflammatory tale from 3 fatty depots. J Am Coll Cardiol 2011 0.75
55 In vivo effect of insulin to decrease matrix metalloproteinase-2 and -9 activity after arterial injury. J Vasc Res 2013 0.75
56 Do thiazolidinediones exert their insulin-sensitizing effect through the suppression of free Fatty acids? Metab Syndr Relat Disord 2004 0.75