PubRank

Yatrik M Shah

Author PubWeight™ 39.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention. Nat Rev Cancer 2012 2.06
2 Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis. Cell Metab 2008 1.67
3 PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators. Toxicology 2007 1.56
4 Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice. Diabetes 2011 1.56
5 Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel disease. Inflamm Bowel Dis 2008 1.50
6 Serum metabolomics reveals irreversible inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity. Chem Res Toxicol 2009 1.46
7 Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice. Gastroenterology 2011 1.38
8 Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation. J Pharmacol Exp Ther 2010 1.31
9 Pioglitazone increases macrophage apoptosis and plaque necrosis in advanced atherosclerotic lesions of nondiabetic low-density lipoprotein receptor-null mice. Circulation 2007 1.30
10 Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice. Gastroenterology 2013 1.30
11 Rifaximin is a gut-specific human pregnane X receptor activator. J Pharmacol Exp Ther 2007 1.26
12 Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis. Hepatology 2011 1.19
13 Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis. Cancer Res 2012 1.17
14 Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity. Hepatology 2012 1.09
15 Intestinal hypoxia-inducible factor-2alpha (HIF-2alpha) is critical for efficient erythropoiesis. J Biol Chem 2011 1.03
16 Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis. Cell Metab 2012 1.01
17 Pregnane X receptor as a target for treatment of inflammatory bowel disorders. Trends Pharmacol Sci 2012 0.99
18 Intestinal HIF2α promotes tissue-iron accumulation in disorders of iron overload with anemia. Proc Natl Acad Sci U S A 2013 0.98
19 Hypoxia-inducible factor-2α is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer. Carcinogenesis 2012 0.97
20 Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4. BMC Genomics 2012 0.96
21 Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling. Blood 2012 0.93
22 Disruption of endothelial peroxisome proliferator-activated receptor γ accelerates diet-induced atherogenesis in LDL receptor-null mice. Arterioscler Thromb Vasc Biol 2011 0.92
23 Hypoxia-inducible factor 1α regulates a SOCS3-STAT3-adiponectin signal transduction pathway in adipocytes. J Biol Chem 2012 0.92
24 Identification of novel proteins induced by estradiol, 4-hydroxytamoxifen and acolbifene in T47D breast cancer cells. Steroids 2006 0.91
25 Fibrinogen-γ proteolysis and solubility dynamics during apoptotic mouse liver injury: heparin prevents and treats liver damage. Hepatology 2011 0.90
26 A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4. Drug Metab Dispos 2008 0.90
27 Control of steroid 21-oic acid synthesis by peroxisome proliferator-activated receptor alpha and role of the hypothalamic-pituitary-adrenal axis. J Biol Chem 2009 0.90
28 Intestinal iron homeostasis and colon tumorigenesis. Nutrients 2013 0.88
29 PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells. Toxicol Sci 2010 0.88
30 The hypoxia-inducible factor-C/EBPα axis controls ethanol-mediated hepcidin repression. Mol Cell Biol 2012 0.85
31 Iron homeostasis in the liver. Compr Physiol 2013 0.84
32 Role of PPARα and HNF4α in stress-mediated alterations in lipid homeostasis. PLoS One 2013 0.82
33 Loss of von Hippel-Lindau protein (VHL) increases systemic cholesterol levels through targeting hypoxia-inducible factor 2α and regulation of bile acid homeostasis. Mol Cell Biol 2014 0.79
34 Hypoxia-inducible factors: a central link between inflammation and cancer. J Clin Invest 2016 0.78
35 In vitro organoid culture of primary mouse colon tumors. J Vis Exp 2013 0.77
36 Transgenic mouse models for alcohol metabolism, toxicity, and cancer. Adv Exp Med Biol 2015 0.76
37 Cholestasis induces reversible accumulation of periplakin in mouse liver. BMC Gastroenterol 2013 0.75
38 Molecular Characterization of Hypoxic Alveolar Epithelial Cells After Lung Contusion Indicates an Important Role for HIF-1α. Ann Surg 2016 0.75