The role of human cytochrome P450 enzymes in the formation of 2-hydroxymetronidazole: CYP2A6 is the high affinity (low Km) catalyst.

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Published in Drug Metab Dispos on June 27, 2013

Authors

Robin E Pearce1, Michael Cohen-Wolkowiez, Mario R Sampson, Gregory L Kearns

Author Affiliations

1: Section of Developmental Pharmacology and Experimental Therapeutics, Division of Pediatric Clinical Pharmacology and Therapeutic Innovation, The Children's Mercy Hospitals, Kansas City, MO 64108, USA. rpearce@cmh.edu

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