Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases.
|
Cancer Res
|
2002
|
3.33
|
2
|
Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase.
|
Clin Cancer Res
|
2003
|
2.26
|
3
|
Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial.
|
Lancet Oncol
|
2010
|
1.97
|
4
|
Advanced stage thymomas and thymic carcinomas: results of multimodality treatments.
|
Ann Thorac Surg
|
2005
|
1.75
|
5
|
Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer.
|
J Clin Endocrinol Metab
|
2010
|
1.68
|
6
|
Mechanical prevention of distal embolization during primary angioplasty: safety, feasibility, and impact on myocardial reperfusion.
|
Circulation
|
2003
|
1.68
|
7
|
Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect.
|
Clin Cancer Res
|
2003
|
1.55
|
8
|
Distal embolization during primary angioplasty: histopathologic features and predictability.
|
Am Heart J
|
2005
|
1.47
|
9
|
A phase II study of intrapleural immuno-chemotherapy, pleurectomy/decortication, radiotherapy, systemic chemotherapy and long-term sub-cutaneous IL-2 in stage II-III malignant pleural mesothelioma.
|
Eur J Cardiothorac Surg
|
2006
|
1.45
|
10
|
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa).
|
Clin Cancer Res
|
2002
|
1.43
|
11
|
Osteopontin expression and prognostic significance in non-small cell lung cancer.
|
Clin Cancer Res
|
2005
|
1.35
|
12
|
Expression and mutational status of c-kit in small-cell lung cancer: prognostic relevance.
|
Clin Cancer Res
|
2004
|
1.25
|
13
|
Sleeve and wedge parenchyma-sparing bronchial resections in low-grade neoplasms of the bronchial airway.
|
J Thorac Cardiovasc Surg
|
2007
|
1.22
|
14
|
Mutational analysis in cytological specimens of advanced lung adenocarcinoma: a sensitive method for molecular diagnosis.
|
J Thorac Oncol
|
2007
|
1.22
|
15
|
WWOX expression in different histologic types and subtypes of non-small cell lung cancer.
|
Clin Cancer Res
|
2007
|
1.06
|
16
|
Cooperative antitumor effect of multitargeted kinase inhibitor ZD6474 and ionizing radiation in glioblastoma.
|
Clin Cancer Res
|
2005
|
1.04
|
17
|
Let-7g and miR-21 expression in non-small cell lung cancer: correlation with clinicopathological and molecular features.
|
Int J Oncol
|
2013
|
1.03
|
18
|
ALK rearrangement in a large series of consecutive non-small cell lung cancers: comparison between a new immunohistochemical approach and fluorescence in situ hybridization for the screening of patients eligible for crizotinib treatment.
|
Arch Pathol Lab Med
|
2014
|
1.03
|
19
|
Role of NRAS mutations as prognostic and predictive markers in metastatic colorectal cancer.
|
Int J Cancer
|
2014
|
1.02
|
20
|
Recommendations for mutational analysis of EGFR in lung carcinoma.
|
Pathologica
|
2010
|
1.00
|
21
|
Percutaneous radiofrequency ablation of lung tumours: results in the mid-term.
|
Eur J Cardiothorac Surg
|
2006
|
1.00
|
22
|
Small cell lung carcinoma (SCLC): the angiogenic phenomenon.
|
Eur J Cardiothorac Surg
|
2002
|
1.00
|
23
|
TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenografts.
|
Proc Natl Acad Sci U S A
|
2007
|
0.96
|
24
|
Anti-tumor activity of the combination of cetuximab, an anti-EGFR blocking monoclonal antibody and ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinases.
|
J Cell Physiol
|
2006
|
0.93
|
25
|
Inherited germline T790M mutation and somatic epidermal growth factor receptor mutations in non-small cell lung cancer patients.
|
J Thorac Oncol
|
2011
|
0.93
|
26
|
Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients.
|
Pharmacogenet Genomics
|
2006
|
0.93
|
27
|
Radiofrequency ablation of lung malignancies: where do we stand?
|
Cardiovasc Intervent Radiol
|
2004
|
0.93
|
28
|
Epidermal growth factor receptor and K-RAS mutations in 411 lung adenocarcinoma: a population-based prospective study.
|
Oncol Rep
|
2009
|
0.93
|
29
|
Malignancies within rhinophyma: report of three new cases and review of the literature.
|
Aesthetic Plast Surg
|
2011
|
0.92
|
30
|
Anaplastic lymphoma kinase gene rearrangements in cytological samples of non-small cell lung cancer: comparison with histological assessment.
|
Cancer Cytopathol
|
2014
|
0.90
|
31
|
Thermal ablation of lung tissue: in vivo experimental comparison of microwave and radiofrequency.
|
Cardiovasc Intervent Radiol
|
2010
|
0.89
|
32
|
Expression of p-AKT and p-mTOR in a large series of bronchopulmonary neuroendocrine tumors.
|
Exp Ther Med
|
2011
|
0.88
|
33
|
An "inflammatory" mitochondrial myopathy. A case report.
|
Neuromuscul Disord
|
2013
|
0.88
|
34
|
EGFR ligands as pharmacodynamic biomarkers in metastatic colorectal cancer patients treated with cetuximab and irinotecan.
|
Target Oncol
|
2013
|
0.88
|
35
|
Expression of endothelin-1 is related to poor prognosis in non-small cell lung carcinoma.
|
Eur J Cancer
|
2005
|
0.88
|
36
|
DeltaN133p53 expression levels in relation to haplotypes of the TP53 internal promoter region.
|
Hum Mutat
|
2010
|
0.88
|
37
|
BRAF status of follicular variant of papillary thyroid carcinoma and its relationship to its clinical and cytological features.
|
Thyroid
|
2010
|
0.87
|
38
|
Biologic effects of radiofrequency thermal ablation on non-small cell lung cancer: results of a pilot study.
|
J Thorac Cardiovasc Surg
|
2006
|
0.86
|
39
|
Interleukin-8 in non-small cell lung carcinoma: relation with angiogenic pattern and p53 alterations.
|
Lung Cancer
|
2005
|
0.86
|
40
|
Glomus tumor of the shoulder: A case report and review of the literature.
|
Oncol Lett
|
2013
|
0.86
|
41
|
Different estrogen receptor beta expression in distinct histologic subtypes of lung adenocarcinoma.
|
Hum Pathol
|
2008
|
0.86
|
42
|
Galectin-3 and oncofetal-fibronectin expression in thyroid neoplasia as assessed by reverse transcription-polymerase chain reaction and immunochemistry in cytologic and pathologic specimens.
|
Thyroid
|
2003
|
0.85
|
43
|
CD34 microvessel density and VEGF expression in basal and squamous cell carcinoma.
|
Pathol Res Pract
|
2003
|
0.85
|
44
|
Four-modality therapy in malignant pleural mesothelioma: a phase II study.
|
J Thorac Oncol
|
2007
|
0.85
|
45
|
Beyond KRAS: perspectives on new potential markers of intrinsic and acquired resistance to epidermal growth factor receptor inhibitors in metastatic colorectal cancer.
|
Ther Adv Med Oncol
|
2009
|
0.84
|
46
|
Tryptase mast cells in malignant pleural mesothelioma as an independent favorable prognostic factor.
|
J Thorac Oncol
|
2009
|
0.83
|
47
|
CLM3, a multitarget tyrosine kinase inhibitor with antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo.
|
J Clin Endocrinol Metab
|
2014
|
0.83
|
48
|
Intraoperative sentinel lymph node mapping in stage I non-small cell lung cancer: detection of micrometastases by polymerase chain reaction.
|
Eur J Cardiothorac Surg
|
2008
|
0.83
|
49
|
EGFR and K-Ras mutations in women with lung adenocarcinoma: implications for treatment strategy definition.
|
J Exp Clin Cancer Res
|
2014
|
0.83
|
50
|
Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer.
|
Eur J Pharmacol
|
2009
|
0.83
|
51
|
CLM94, a novel cyclic amide with anti-VEGFR-2 and antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo.
|
J Clin Endocrinol Metab
|
2012
|
0.82
|
52
|
Effect of the p53 codon 72 and intron 3 polymorphisms on non-small cell lung cancer (NSCLC) prognosis.
|
Cancer Invest
|
2008
|
0.82
|
53
|
Antitumor activity of ZD6474, a vascular endothelial growth factor-2 and epidermal growth factor receptor small molecule tyrosine kinase inhibitor, in combination with SC-236, a cyclooxygenase-2 inhibitor.
|
Clin Cancer Res
|
2005
|
0.82
|
54
|
Tumour necrosis factor-alpha: prognostic role and relationship with interleukin-8 and endothelin-1 in non-small cell lung cancer.
|
Int J Mol Med
|
2006
|
0.82
|
55
|
Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo.
|
Neoplasia
|
2011
|
0.81
|
56
|
Advanced non-small cell lung cancer management in patients progressing after first-line treatment: results of the cross-sectional phase of the Italian LIFE observational study.
|
J Cancer Res Clin Oncol
|
2014
|
0.81
|
57
|
MERRF syndrome without ragged-red fibers: the need for molecular diagnosis.
|
Biochem Biophys Res Commun
|
2007
|
0.81
|
58
|
Multimodality treatment of malignant pleural mesothelioma with or without immunotherapy: does it change anything?
|
Interact Cardiovasc Thorac Surg
|
2010
|
0.80
|
59
|
p95HER2 truncated form in resected non-small cell lung cancer.
|
J Thorac Oncol
|
2012
|
0.80
|
60
|
Expression of cyclooxygenase-2 and its correlation with vasogenic brain edema in human intracranial meningiomas.
|
Cancer Invest
|
2007
|
0.80
|
61
|
Coexistence of TERT promoter and BRAF mutations in cutaneous melanoma is associated with more clinicopathological features of aggressiveness.
|
Virchows Arch
|
2015
|
0.80
|
62
|
EML4-ALK translocation in both metachronous second primary lung sarcomatoid carcinoma and lung adenocarcinoma: a case report.
|
Lung Cancer
|
2013
|
0.80
|
63
|
Phosphatidylinositol-3-kinase α catalytic subunit gene somatic mutations in bronchopulmonary neuroendocrine tumours.
|
Oncol Rep
|
2012
|
0.80
|
64
|
CDC25B: relationship with angiogenesis and prognosis in non-small cell lung carcinoma.
|
Hum Pathol
|
2007
|
0.80
|
65
|
Regulation of telomerase and its hTERT messenger in colorectal cancer.
|
Oncol Rep
|
2004
|
0.80
|
66
|
Prognostic impact of p53 Pro72 homozygous genotype in non-small cell lung cancer patients.
|
Oncol Rep
|
2008
|
0.80
|
67
|
Meningeal hemangiopericytoma metastatic to the adrenal gland with multiple metastases to bones and lungs: a case report.
|
Tumori
|
2004
|
0.79
|
68
|
Antiproliferative and proapoptotic activity of sunitinib on endothelial and anaplastic thyroid cancer cells via inhibition of Akt and ERK1/2 phosphorylation and by down-regulation of cyclin-D1.
|
J Clin Endocrinol Metab
|
2013
|
0.79
|
69
|
Applications of tissue microarray technology in immunohistochemistry: a study on c-kit expression in small cell lung cancer.
|
Hum Pathol
|
2004
|
0.77
|
70
|
Benefit from a high dose of gefitinib in a woman with lung adenocarcinoma and an epidermal growth factor receptor tyrosine-kinase acquired mutation.
|
Mol Med Rep
|
2011
|
0.77
|
71
|
The administration of gefitinib in patients with advanced non-small-cell lung cancer after the failure of erlotinib.
|
Cancer Chemother Pharmacol
|
2012
|
0.77
|
72
|
P2X7 protein expression and polymorphism in non-small cell lung cancer (NSCLC).
|
J Negat Results Biomed
|
2014
|
0.77
|
73
|
Differential expression of extracellular matrix constituents and cell adhesion molecules between malignant pleural mesothelioma and mesothelial hyperplasia.
|
J Thorac Oncol
|
2013
|
0.77
|
74
|
CXC chemokine receptor 4 immunodetection in the follicular variant of papillary thyroid carcinoma: comparison to galectin-3 and hector battifora mesothelial cell-1.
|
Thyroid
|
2010
|
0.77
|
75
|
Expression of endothelin 1 and its angiogenic role in meningiomas.
|
Virchows Arch
|
2006
|
0.77
|
76
|
Immunohistochemical and molecular study of radiation-induced multiple meningiomas with pleural and pulmonary metastasis.
|
Tumori
|
2004
|
0.76
|
77
|
KIF5B/RET fusion gene analysis in a selected series of cytological specimens of EGFR, KRAS and EML4-ALK wild-type adenocarcinomas of the lung.
|
Lung Cancer
|
2013
|
0.76
|
78
|
Mutations of Fas (APO-1/CD95) and p53 genes in nonmelanoma skin cancer.
|
J Cutan Med Surg
|
2002
|
0.75
|
79
|
Clear cell adenocarcinoma of the base of the tongue: a case report and review of the literature.
|
Ear Nose Throat J
|
2011
|
0.75
|
80
|
Discordant somatic and germline VEGF-A genotype in a cancer patient resistant to paclitaxel/bevacizumab with chemosensitive hepatic metastasis.
|
Pharmacogenomics
|
2009
|
0.75
|
81
|
Advances in molecular diagnostics for mitochondrial diseases.
|
Expert Opin Med Diagn
|
2009
|
0.75
|
82
|
Novel Pyrazolopyrimidine Derivatives as Tyrosine Kinase Inhibitors with Antitumoral Activity in Vitro and in Vivo in Papillary Dedifferentiated Thyroid Cancer.
|
Endocrinology
|
2011
|
0.75
|
83
|
Distal embolization during angioplasty for acute myocardial infarction: is pharmacological protection enough?
|
Thromb Haemost
|
2005
|
0.75
|
84
|
Novel MTCYB mutation in a young patient with recurrent stroke-like episodes and status epilepticus.
|
Am J Med Genet A
|
2014
|
0.75
|
85
|
Laser capture microdissection: a tool for the molecular characterization of histologic subtypes of lung adenocarcinoma.
|
Int J Mol Med
|
2009
|
0.75
|
86
|
The role of somatostatin in vasogenic meningioma associated brain edema.
|
Tumori
|
2003
|
0.75
|