Published in PLoS One on June 24, 2013
CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells. PLoS One (2014) 0.84
Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis. PLoS One (2014) 0.84
RNA binding protein-mediated post-transcriptional gene regulation in medulloblastoma. Mol Cells (2014) 0.82
CARP-1/CCAR1: a biphasic regulator of cancer cell growth and apoptosis. Oncotarget (2015) 0.80
Identification and Testing of Novel CARP-1 Functional Mimetic Compounds as Inhibitors of Non-Small Cell Lung and Triple Negative Breast Cancers. J Biomed Nanotechnol (2015) 0.80
Mechanisms of neuroblastoma cell growth inhibition by CARP-1 functional mimetics. PLoS One (2014) 0.78
CARP-1 functional mimetics are novel inhibitors of drug-resistant triple negative breast cancers. Oncotarget (2016) 0.75
In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc (2007) 12.39
Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol (2007) 10.23
Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol (2011) 6.67
Novel mutations target distinct subgroups of medulloblastoma. Nature (2012) 4.82
Late neurocognitive sequelae in survivors of brain tumours in childhood. Lancet Oncol (2004) 3.56
Machine learning and its applications to biology. PLoS Comput Biol (2007) 2.57
Medulloblastoma: signalling a change in treatment. Lancet Oncol (2004) 1.96
Histogenesis of cortical layers in human cerebellum, particularly the lamina dissecans. J Comp Neurol (1970) 1.85
Linking JNK signaling to NF-kappaB: a key to survival. J Cell Sci (2004) 1.84
Neurotrophic factors and their receptors. Curr Opin Cell Biol (1995) 1.74
TP53 family members and human cancers. Hum Mutat (2003) 1.70
CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes. Mol Cell (2008) 1.66
Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not. Nature (2010) 1.56
Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D. J Neurooncol (2007) 1.50
ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling. Biochem Pharmacol (2009) 1.48
NF-kappaB is required for UV-induced JNK activation via induction of PKCdelta. Mol Cell (2006) 1.41
Apoptosis induced by p75NTR overexpression requires Jun kinase-dependent phosphorylation of Bad. J Neurosci (2003) 1.36
Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437. J Biol Chem (2003) 1.33
The role of matrix metalloproteinases in glioma invasion. Front Biosci (2003) 1.33
Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IkappaB alpha phosphorylation and degradation. Mol Cell Biol (1998) 1.32
Tumor cell invasion assays. Methods Mol Biol (2005) 1.29
Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proc Natl Acad Sci U S A (1994) 1.27
Deregulated expression of PAX5 in medulloblastoma. Proc Natl Acad Sci U S A (1995) 1.25
Cell cycle- and apoptosis-regulatory protein-1 is involved in apoptosis signaling by epidermal growth factor receptor. J Biol Chem (2006) 1.22
Advances in small molecules promoting neurotrophic function. Pharmacol Ther (2007) 1.19
Identification of a novel pro-apopotic function of NF-kappaB in the DNA damage response. J Cell Mol Med (2009) 1.17
Neurotrophins: the biological paradox of survival factors eliciting apoptosis. Cell Death Differ (1998) 1.14
miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma. Neuro Oncol (2010) 1.10
p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17. J Biol Chem (2010) 1.09
NF-κB is required for Smac mimetic-mediated sensitization of glioblastoma cells for γ-irradiation-induced apoptosis. Mol Cancer Ther (2011) 1.06
Proneurotrophin-3 is a neuronal apoptotic ligand: evidence for retrograde-directed cell killing. J Neurosci (2009) 1.03
Nerve growth factor induces apoptosis in human medulloblastoma cell lines that express TrkA receptors. J Neurosci (1997) 1.02
Activation of neurotrophin-3 receptor TrkC induces apoptosis in medulloblastomas. Cancer Res (1999) 1.02
Transactivator of transcription-tagged cell cycle and apoptosis regulatory protein-1 peptides suppress the growth of human breast cancer cells in vitro and in vivo. Mol Cancer Ther (2007) 1.00
Tumor environment dictates medulloblastoma cancer stem cell expression and invasive phenotype. Mol Cancer Res (2008) 0.99
Treatment of medulloblastoma with a modified measles virus. Neuro Oncol (2010) 0.99
Small molecule activators of the Trk receptors for neuroprotection. BMC Neurosci (2008) 0.98
Antagonists of anaphase-promoting complex (APC)-2-cell cycle and apoptosis regulatory protein (CARP)-1 interaction are novel regulators of cell growth and apoptosis. J Biol Chem (2011) 0.98
Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas. Neuro Oncol (2012) 0.97
Inhibition of NFkappaB by activated c-Jun NH2 terminal kinase 1 acts as a switch for C2C12 cell death under excessive stretch. Apoptosis (2009) 0.88
The inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappaB and potentiate apoptosis. Biochem J (2004) 0.88
Use of cultured neurons and neuronal cell lines to study morphological, biochemical, and molecular changes occurring in cell death. Methods Cell Biol (1995) 0.87
The invasiveness of five medulloblastoma cell lines in collagen gels. J Neurooncol (2009) 0.81
Neurotrophin and neurotrophin receptor proteins in medulloblastomas and other primitive neuroectodermal tumors of the pediatric central nervous system. Am J Pathol (1996) 0.81
Matrix metalloproteinase expression in childhood medulloblastomas/primitive neuroectodermal tumors. In Vivo (2000) 0.79
Medulloblastoma displays distinct regional matrix metalloprotease expression. J Neurooncol (2001) 0.79
Distinct subsets of microRNAs are expressed differentially in the human placentas of patients with preeclampsia. Am J Obstet Gynecol (2007) 2.78
Akt, FoxO and regulation of apoptosis. Biochim Biophys Acta (2011) 2.62
Machine learning and its applications to biology. PLoS Comput Biol (2007) 2.57
Onto-Tools: new additions and improvements in 2006. Nucleic Acids Res (2007) 2.33
The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women. Microbiome (2014) 2.24
The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms. Cancer Res (2008) 2.19
Pathologically and biologically distinct types of epithelium in intraductal papillary mucinous neoplasms: delineation of an "intestinal" pathway of carcinogenesis in the pancreas. Am J Surg Pathol (2004) 1.96
Synthesis of some new pyrazolo[3,4-d]pyrimidine derivatives of expected anticancer and radioprotective activity. Eur J Med Chem (2009) 1.57
Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R. Int J Cancer (2008) 1.50
Epidermal growth factor receptor (EGFR)-related protein inhibits multiple members of the EGFR family in colon and breast cancer cells. Mol Cancer Ther (2005) 1.44
Identification and biological activities of new taccalonolide microtubule stabilizers. J Med Chem (2011) 1.38
The transcriptome of the fetal inflammatory response syndrome. Am J Reprod Immunol (2010) 1.37
Autoantibody approach for serum-based detection of head and neck cancer. Cancer Epidemiol Biomarkers Prev (2007) 1.35
Age-related increase in colorectal cancer stem cells in macroscopically normal mucosa of patients with adenomas: a risk factor for colon cancer. Biochem Biophys Res Commun (2008) 1.31
Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies. Brain Res (2006) 1.27
Upregulation of miR-150* and miR-630 induces apoptosis in pancreatic cancer cells by targeting IGF-1R. PLoS One (2013) 1.24
Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF. J Hematol Oncol (2012) 1.23
Cigarette smoke, inflammation, and lung injury: a mechanistic perspective. J Toxicol Environ Health B Crit Rev (2009) 1.22
Cell cycle- and apoptosis-regulatory protein-1 is involved in apoptosis signaling by epidermal growth factor receptor. J Biol Chem (2006) 1.22
Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage. Exp Cell Res (2008) 1.19
Folic acid supplementation inhibits recurrence of colorectal adenomas: a randomized chemoprevention trial. World J Gastroenterol (2008) 1.17
Schlafen 3, a novel gene, regulates colonic mucosal growth during aging. Am J Physiol Gastrointest Liver Physiol (2009) 1.17
Emerging therapies in gastrointestinal cancers. World J Gastroenterol (2006) 1.11
The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation. Cancer Res (2009) 1.11
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. Exp Cell Res (2008) 1.11
Epidermal growth factor receptor-related peptide inhibits growth of PC-3 prostate cancer cells. Mol Cancer Ther (2004) 1.11
Curcumin synergizes with resveratrol to inhibit colon cancer. Nutr Cancer (2009) 1.09
miR-210 targets iron-sulfur cluster scaffold homologue in human trophoblast cell lines: siderosis of interstitial trophoblasts as a novel pathology of preterm preeclampsia and small-for-gestational-age pregnancies. Am J Pathol (2011) 1.06
New Onto-Tools: Promoter-Express, nsSNPCounter and Onto-Translate. Nucleic Acids Res (2006) 1.06
Cell cycle and apoptosis regulatory protein-1: a novel regulator of apoptosis in the colonic mucosa during aging. Am J Physiol Gastrointest Liver Physiol (2007) 1.06
Differential expression of microRNAs with progression of gestation and inflammation in the human chorioamniotic membranes. Am J Obstet Gynecol (2007) 1.06
A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death. Proc Natl Acad Sci U S A (2009) 1.04
Antagonist analogue of 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest. J Med Chem (2004) 1.00
Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via Smad- and p38-dependent mechanisms. Am J Pathol (2008) 1.00
CB694, a novel antimitotic with antitumor activities. Int J Cancer (2006) 1.00
Signature pathways identified from gene expression profiles in the human uterine cervix before and after spontaneous term parturition. Am J Obstet Gynecol (2007) 1.00
Transactivator of transcription-tagged cell cycle and apoptosis regulatory protein-1 peptides suppress the growth of human breast cancer cells in vitro and in vivo. Mol Cancer Ther (2007) 1.00
EGFR regulation of colon cancer stem-like cells during aging and in response to the colonic carcinogen dimethylhydrazine. Am J Physiol Gastrointest Liver Physiol (2012) 1.00
Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term. J Perinat Med (2010) 1.00
A proposal for a new and more practical grading scheme for pancreatic ductal adenocarcinoma. Am J Surg Pathol (2005) 0.99
Induction of apoptosis of human B-CLL and ALL cells by a novel retinoid and its nonretinoidal analog. Blood (2002) 0.99
5-(Adamantan-1-yl)-3-[(4-fluoro-anilino)meth-yl]-2,3-di-hydro-1,3,4-oxa-diazole-2-thione. Acta Crystallogr Sect E Struct Rep Online (2013) 0.99
Antagonists of anaphase-promoting complex (APC)-2-cell cycle and apoptosis regulatory protein (CARP)-1 interaction are novel regulators of cell growth and apoptosis. J Biol Chem (2011) 0.98
Infrequent Fas mutations but no Bax or p53 mutations in early mycosis fungoides: a possible mechanism for the accumulation of malignant T lymphocytes in the skin. J Invest Dermatol (2002) 0.98
Region-specific gene expression profiling: novel evidence for biological heterogeneity of the human amnion. Biol Reprod (2008) 0.97
MicroRNA expression profiling of the human uterine cervix after term labor and delivery. Am J Obstet Gynecol (2009) 0.96
Dynamic gene expression in the human cerebral cortex distinguishes children from adults. PLoS One (2012) 0.96
Placental protein 13 (galectin-13) has decreased placental expression but increased shedding and maternal serum concentrations in patients presenting with preterm pre-eclampsia and HELLP syndrome. Virchows Arch (2008) 0.96
An imbalance between angiogenic and anti-angiogenic factors precedes fetal death in a subset of patients: results of a longitudinal study. J Matern Fetal Neonatal Med (2010) 0.95
Regression of early and intermediate stages of colon cancer by targeting multiple members of the EGFR family with EGFR-related protein. Cancer Res (2007) 0.94
Ponatinib (AP24534) is a novel potent inhibitor of oncogenic RET mutants associated with thyroid cancer. J Clin Endocrinol Metab (2013) 0.93
The transcriptome of cervical ripening in human pregnancy before the onset of labor at term: identification of novel molecular functions involved in this process. J Matern Fetal Neonatal Med (2009) 0.93
ErbB-inhibitory protein: a modified ectodomain of epidermal growth factor receptor synergizes with dasatinib to inhibit growth of breast cancer cells. Mol Cancer Ther (2010) 0.93
A role for mannose-binding lectin, a component of the innate immune system in pre-eclampsia. Am J Reprod Immunol (2008) 0.93
Age-related loss of EGF-receptor related protein (ERRP) in the aging colon is a potential risk factor for colon cancer. Mech Ageing Dev (2004) 0.93
Emergence of hormonal and redox regulation of galectin-1 in placental mammals: implication in maternal-fetal immune tolerance. Proc Natl Acad Sci U S A (2008) 0.92
Anti-inflammatory effect of Euphorbia hirta in an adjuvant-induced arthritic murine model. Immunol Invest (2014) 0.92
Mechanisms of curcumin- and EGF-receptor related protein (ERRP)-dependent growth inhibition of colon cancer cells. Nutr Cancer (2006) 0.91
Severe preeclampsia is characterized by increased placental expression of galectin-1. J Matern Fetal Neonatal Med (2008) 0.91
A novel mechanism of cell growth regulation by Cell Cycle and Apoptosis Regulatory Protein (CARP)-1. J Mol Signal (2010) 0.91
Surfactant protein-A as an anti-inflammatory component in the amnion: implications for human pregnancy. J Immunol (2010) 0.90
Peripheral CD300a+CD8+ T lymphocytes with a distinct cytotoxic molecular signature increase in pregnant women with chronic chorioamnionitis. Am J Reprod Immunol (2011) 0.90
Induction of apoptosis in retinoid-refractory acute myelogenous leukemia by a novel AHPN analog. Blood (2003) 0.90
Increased ceramide accumulation correlates with downregulation of the autophagy protein ATG-7 in MCF-7 cells sensitized to photodamage. Arch Biochem Biophys (2009) 0.90
The molecular basis for sonographic cervical shortening at term: identification of differentially expressed genes and the epithelial-mesenchymal transition as a function of cervical length. Am J Obstet Gynecol (2010) 0.90
Squamous cell carcinoma complicating chronic suppurative hydradenitis. Am Surg (2011) 0.90
Rare occurrence of gastric pseudomelanosis. Gastrointest Endosc (2009) 0.89
Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells. Am J Physiol Gastrointest Liver Physiol (2004) 0.89
Developmental changes in the transcriptome of human cerebral cortex tissue: long noncoding RNA transcripts. Cereb Cortex (2013) 0.89
Short rib-polydactyly syndrome: a case report. Turk J Pediatr (2004) 0.89
Insights into the physiology of childbirth using transcriptomics. PLoS Med (2006) 0.89
Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers. Int J Cancer (2009) 0.89
Mitochondrial manganese superoxide dismutase mRNA expression in human chorioamniotic membranes and its association with labor, inflammation, and infection. J Matern Fetal Neonatal Med (2009) 0.89
Characterization of the transcriptome of chorioamniotic membranes at the site of rupture in spontaneous labor at term. Am J Obstet Gynecol (2010) 0.89
Metformin rescues the myocardium from doxorubicin-induced energy starvation and mitochondrial damage in rats. Oxid Med Cell Longev (2012) 0.88
Hexosamine induction of oxidative stress, hypertrophy and laminin expression in renal mesangial cells: effect of the anti-oxidant alpha-lipoic acid. Cell Biochem Funct (2007) 0.88
Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines. Cancer Chemother Pharmacol (2009) 0.88
Epidermal growth factor receptor-related protein: a potential therapeutic agent for colorectal cancer. Gastroenterology (2003) 0.88
Folic acid mediated attenuation of loss of heterozygosity of DCC tumor suppressor gene in the colonic mucosa of patients with colorectal adenomas. Cancer Detect Prev (2003) 0.88
IGF-1 increases laminin, cyclin D1, and p21Cip1 expression in glomerular mesangial cells: an investigation of the intracellular signaling pathway and cell-cycle progression. J Cell Biochem (2006) 0.88
Evidence of an imbalance of angiogenic/antiangiogenic factors in massive perivillous fibrin deposition (maternal floor infarction): a placental lesion associated with recurrent miscarriage and fetal death. Am J Obstet Gynecol (2013) 0.87
Plasma concentrations of angiogenic/anti-angiogenic factors have prognostic value in women presenting with suspected preeclampsia to the obstetrical triage area: a prospective study. J Matern Fetal Neonatal Med (2013) 0.87
5-(Adamantan-1-yl)-N-methyl-1,3,4-thia-diazol-2-amine. Acta Crystallogr Sect E Struct Rep Online (2013) 0.87
Effect of long-term human exposure to environmental heavy metals on the expression of detoxification and DNA repair genes. Environ Pollut (2013) 0.87
Glycine betaine may have opposite effects on protein stability at high and low pH values. Biochim Biophys Acta (2009) 0.86
Withaferin A inhibits the proteasome activity in mesothelioma in vitro and in vivo. PLoS One (2012) 0.86
A decrease in maternal plasma concentrations of sVEGFR-2 precedes the clinical diagnosis of preeclampsia. Am J Obstet Gynecol (2010) 0.85
MPO-ANCA-associated small vessel vasculitis presenting as fever of unknown origin. Report of one case. Nephron (2002) 0.85
Transforming growth factor-beta (TGF-beta)-resistant B cells from chronic lymphocytic leukemia patients contain recurrent mutations in the signal sequence of the type I TGF-beta receptor. Cancer Detect Prev (2004) 0.85
Chorioamnionitis and increased galectin-1 expression in PPROM --an anti-inflammatory response in the fetal membranes? Am J Reprod Immunol (2008) 0.85
Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis. Mol Cell Biochem (2014) 0.84