Early brain enlargement and elevated extra-axial fluid in infants who develop autism spectrum disorder.

PubWeight™: 1.21‹?› | Rank: Top 10%

🔗 View Article (PMC 3754460)

Published in Brain on July 09, 2013

Authors

Mark D Shen1, Christine W Nordahl, Gregory S Young, Sandra L Wootton-Gorges, Aaron Lee, Sarah E Liston, Kayla R Harrington, Sally Ozonoff, David G Amaral

Author Affiliations

1: The Medical Investigation of Neurodevelopmental Disorders Institute and Department of Psychiatry and Behavioural Sciences, UC Davis School of Medicine, University of California, Davis, Sacramento, CA 95817, USA.

Articles citing this

Developmental pathways to autism: a review of prospective studies of infants at risk. Neurosci Biobehav Rev (2013) 1.56

Early generalized overgrowth in autism spectrum disorder: prevalence rates, gender effects, and clinical outcomes. J Am Acad Child Adolesc Psychiatry (2014) 1.45

Development and functions of the choroid plexus-cerebrospinal fluid system. Nat Rev Neurosci (2015) 1.14

Diagnostic stability in young children at risk for autism spectrum disorder: a baby siblings research consortium study. J Child Psychol Psychiatry (2015) 1.10

A New Methodology of Viewing Extra-Axial Fluid and Cortical Abnormalities in Children with Autism via Transcranial Ultrasonography. Front Hum Neurosci (2014) 1.09

Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Mol Psychiatry (2016) 1.05

Behavioral, cognitive, and adaptive development in infants with autism spectrum disorder in the first 2 years of life. J Neurodev Disord (2015) 1.03

Longitudinal volumetric brain changes in autism spectrum disorder ages 6-35 years. Autism Res (2014) 0.96

Functional connectivity in the first year of life in infants at-risk for autism: a preliminary near-infrared spectroscopy study. Front Hum Neurosci (2013) 0.95

Eye Tracking Reveals Abnormal Visual Preference for Geometric Images as an Early Biomarker of an Autism Spectrum Disorder Subtype Associated With Increased Symptom Severity. Biol Psychiatry (2015) 0.93

Altered corpus callosum morphology associated with autism over the first 2 years of life. Brain (2015) 0.90

Is birth a critical period in the pathogenesis of autism spectrum disorders? Nat Rev Neurosci (2015) 0.87

Commentary: Structural and functional features of central nervous system lymphatic vessels. Front Neurosci (2015) 0.87

Why autism must be taken apart. J Autism Dev Disord (2014) 0.86

A comparison of neuroimaging findings in childhood onset schizophrenia and autism spectrum disorder: a review of the literature. Front Psychiatry (2013) 0.85

The Human Model: Changing Focus on Autism Research. Biol Psychiatry (2015) 0.85

The attentive brain: insights from developmental cognitive neuroscience. Nat Rev Neurosci (2015) 0.85

Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases. Nat Genet (2017) 0.84

Autism-epilepsy phenotype with macrocephaly suggests PTEN, but not GLIALCAM, genetic screening. BMC Med Genet (2014) 0.83

Early brain development in infants at high risk for autism spectrum disorder. Nature (2017) 0.83

Brain imaging research in autism spectrum disorders: in search of neuropathology and health across the lifespan. Curr Opin Psychiatry (2015) 0.83

The first 1000 days of the autistic brain: a systematic review of diffusion imaging studies. Front Hum Neurosci (2015) 0.82

Developmental neurotoxicity of inhaled ambient ultrafine particle air pollution: Parallels with neuropathological and behavioral features of autism and other neurodevelopmental disorders. Neurotoxicology (2015) 0.82

Infant Development in Fragile X Syndrome: Cross-Syndrome Comparisons. J Autism Dev Disord (2016) 0.78

The effect of gender on the neuroanatomy of children with autism spectrum disorders: a support vector machine case-control study. Mol Autism (2016) 0.78

Increased Surface Area, but not Cortical Thickness, in a Subset of Young Boys With Autism Spectrum Disorder. Autism Res (2015) 0.78

Myosin Id is required for planar cell polarity in ciliated tracheal and ependymal epithelial cells. Cytoskeleton (Hoboken) (2015) 0.78

Increased Extra-axial Cerebrospinal Fluid in High-Risk Infants Who Later Develop Autism. Biol Psychiatry (2017) 0.77

Future directions for research in autism spectrum disorders. J Clin Child Adolesc Psychol (2014) 0.77

Reduced engagement with social stimuli in 6-month-old infants with later autism spectrum disorder: a longitudinal prospective study of infants at high familial risk. J Neurodev Disord (2016) 0.77

Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder. Mol Psychiatry (2017) 0.76

Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A Survey. Front Hum Neurosci (2016) 0.76

Neural circuitry at age 6 months associated with later repetitive behavior and sensory responsiveness in autism. Mol Autism (2017) 0.75

Candidate Biomarkers in Children with Autism Spectrum Disorder: A Review of MRI Studies. Neurosci Bull (2017) 0.75

Aberrant Development of Speech Processing in Young Children with Autism: New Insights from Neuroimaging Biomarkers. Front Neurosci (2016) 0.75

Phenotyping, Etiological Factors, and Biomarkers: Toward Precision Medicine in Autism Spectrum Disorders. J Dev Behav Pediatr (2016) 0.75

No evidence of early head circumference enlargements in children later diagnosed with autism in Israel. Mol Autism (2017) 0.75

Toward a conceptual framework for early brain and behavior development in autism. Mol Psychiatry (2017) 0.75

White matter compromise in autism? Differentiating motion confounds from true differences in diffusion tensor imaging. Autism Res (2017) 0.75

Reduced subarachnoid fluid diffusion in enlarged subarachnoid spaces of infancy. Neuroradiol J (2017) 0.75

Articles cited by this

Fast robust automated brain extraction. Hum Brain Mapp (2002) 41.79

Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Trans Med Imaging (2001) 25.22

A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging (1998) 23.54

Prevalence of autism spectrum disorders--Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008. MMWR Surveill Summ (2012) 11.55

Behavioral manifestations of autism in the first year of life. Int J Dev Neurosci (2005) 6.56

Recurrence risk for autism spectrum disorders: a Baby Siblings Research Consortium study. Pediatrics (2011) 6.08

Unusual brain growth patterns in early life in patients with autistic disorder: an MRI study. Neurology (2001) 5.92

Randomized, controlled trial of an intervention for toddlers with autism: the Early Start Denver Model. Pediatrics (2009) 5.91

Evidence of brain overgrowth in the first year of life in autism. JAMA (2003) 5.47

A prospective study of the emergence of early behavioral signs of autism. J Am Acad Child Adolesc Psychiatry (2010) 4.10

Magnetic resonance imaging and head circumference study of brain size in autism: birth through age 2 years. Arch Gen Psychiatry (2005) 3.94

Evidence-based comprehensive treatments for early autism. J Clin Child Adolesc Psychol (2008) 3.86

Differences in white matter fiber tract development present from 6 to 24 months in infants with autism. Am J Psychiatry (2012) 3.38

The amygdala is enlarged in children but not adolescents with autism; the hippocampus is enlarged at all ages. J Neurosci (2004) 3.30

Infant neural sensitivity to dynamic eye gaze is associated with later emerging autism. Curr Biol (2012) 3.08

Sibling recurrence and the genetic epidemiology of autism. Am J Psychiatry (2010) 3.07

Multiplicity of cerebrospinal fluid functions: New challenges in health and disease. Cerebrospinal Fluid Res (2008) 2.95

Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism. J Neurosci (2010) 2.70

Analyze: a comprehensive, operator-interactive software package for multidimensional medical image display and analysis. Comput Med Imaging Graph (1990) 2.60

A prospective case series of high-risk infants who developed autism. J Autism Dev Disord (2007) 2.35

What are infant siblings teaching us about autism in infancy? Autism Res (2009) 2.32

Macrocephaly in children and adults with autism. J Am Acad Child Adolesc Psychiatry (1997) 2.26

The electrical conductivity of human cerebrospinal fluid at body temperature. IEEE Trans Biomed Eng (1997) 2.08

Mapping the brain in autism. A voxel-based MRI study of volumetric differences and intercorrelations in autism. Brain (2004) 1.97

Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species. Cerebrospinal Fluid Res (2004) 1.83

EEG complexity as a biomarker for autism spectrum disorder risk. BMC Med (2011) 1.73

Brain enlargement is associated with regression in preschool-age boys with autism spectrum disorders. Proc Natl Acad Sci U S A (2011) 1.73

How early do parent concerns predict later autism diagnosis? J Dev Behav Pediatr (2009) 1.70

Idiopathic external hydrocephalus: natural history and relationship to benign familial macrocephaly. Pediatrics (1986) 1.64

"Benign" extra-axial fluid in survivors of neonatal intensive care. Arch Pediatr Adolesc Med (2004) 1.51

On the Pacchionian Bodies. J Anat (1920) 1.47

Benign external hydrocephalus: a review, with emphasis on management. Neurosurg Rev (2011) 1.44

External hydrocephalus: radiologic spectrum and differentiation from cerebral atrophy. AJR Am J Roentgenol (1987) 1.43

Rate of head growth decelerates and symptoms worsen in the second year of life in autism. Biol Psychiatry (2006) 1.41

Developmental trajectories of resting EEG power: an endophenotype of autism spectrum disorder. PLoS One (2012) 1.39

The development of young siblings of children with autism from 4 to 54 months. J Autism Dev Disord (2007) 1.35

Intracranial incidental findings on brain MR images in a pediatric neurology practice: a retrospective study. J Neurol Sci (2007) 1.27

Cerebrospinal fluid outflow: an evolving perspective. Brain Res Bull (2008) 1.25

Brief report: methods for acquiring structural MRI data in very young children with autism without the use of sedation. J Autism Dev Disord (2007) 1.20

Increased rate of amygdala growth in children aged 2 to 4 years with autism spectrum disorders: a longitudinal study. Arch Gen Psychiatry (2012) 1.20

Developmental trajectories in children with and without autism spectrum disorders: the first 3 years. Child Dev (2012) 1.19

Neuropathology and structural changes in hydrocephalus. Dev Disabil Res Rev (2010) 1.15

Deficient cortical development in the hydrocephalic Texas (H-Tx) rat: a role for CSF. Brain (2002) 1.12

Developmental prognosis for infants with benign enlargement of the subarachnoid spaces. Dev Med Child Neurol (1987) 1.06

Benign subdural collections of infancy. Pediatrics (1981) 1.05

The widened frontal subarachnoid space. A CT comparative study between macrocephalic, microcephalic, and normocephalic infants and children. Childs Nerv Syst (1992) 1.02

Pseudohydrocephalus-megalocephaly, increased intracranial pressure and widened subarachnoid space. Neuropadiatrie (1978) 1.01

Ultrasonographic measurement of subarachnoid space in normal infants and children. Pediatr Neurol (2001) 1.01

Development of arachnoid villi and granulations in man. Acta Anat (Basel) (1982) 0.99

Benign extracerebral fluid collections in infancy: clinical presentation and long-term follow-up. J Neurosurg (2007) 0.97

CSF dynamics in hydrocephalus--with special attention to external hydrocephalus. Brain Dev (1984) 0.97

The importance of lymphatics in cerebrospinal fluid transport. Lymphat Res Biol (2003) 0.96

Brain morphometry volume in autistic spectrum disorder: a magnetic resonance imaging study of adults. Psychol Med (2008) 0.95

Measurement of cerebrospinal fluid output through external ventricular drainage in one hundred infants and children: correlation with cerebrospinal fluid production. Pediatr Neurosurg (2002) 0.90

The subarachnoid spaces in children: normal variations in size. Radiology (1983) 0.89

Ventriculomegaly and pericerebral CSF collection in the fetus: early stage of benign external hydrocephalus? Childs Nerv Syst (2001) 0.81

Dilatation of the subarachnoid pericerebral space and absorption of cerebrospinal fluid in the infant. Anat Clin (1985) 0.77

Articles by these authors

Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature (2009) 7.39

Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study. Lancet (2009) 7.23

Genetic heritability and shared environmental factors among twin pairs with autism. Arch Gen Psychiatry (2011) 6.98

Recurrence risk for autism spectrum disorders: a Baby Siblings Research Consortium study. Pediatrics (2011) 6.08

A prospective study of the emergence of early behavioral signs of autism. J Am Acad Child Adolesc Psychiatry (2010) 4.10

A decision rule for identifying children at low risk for brain injuries after blunt head trauma. Ann Emerg Med (2003) 3.38

The amygdala is enlarged in children but not adolescents with autism; the hippocampus is enlarged at all ages. J Neurosci (2004) 3.30

Macaque monkey retrosplenial cortex: II. Cortical afferents. J Comp Neurol (2003) 3.15

Head circumference and height in autism: a study by the Collaborative Program of Excellence in Autism. Am J Med Genet A (2006) 3.01

Annotation: what do we know about sensory dysfunction in autism? A critical review of the empirical evidence. J Child Psychol Psychiatry (2005) 2.61

A prospective study of response to name in infants at risk for autism. Arch Pediatr Adolesc Med (2007) 2.54

Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from mothers of children with autism. Brain Behav Immun (2008) 2.50

Perirhinal and parahippocampal cortices of the macaque monkey: projections to the neocortex. J Comp Neurol (2002) 2.44

Some observations on cortical inputs to the macaque monkey amygdala: an anterograde tracing study. J Comp Neurol (2002) 2.42

Visual Fixation Patterns during Reciprocal Social Interaction Distinguish a Subgroup of 6-Month-Old Infants At-Risk for Autism from Comparison Infants. J Autism Dev Disord (2006) 2.40

Neuroanatomical assessment of biological maturity. Curr Biol (2012) 2.40

Gaze behavior and affect at 6 months: predicting clinical outcomes and language development in typically developing infants and infants at risk for autism. Dev Sci (2009) 2.35

Guidelines for imaging and staging of neuroblastic tumors: consensus report from the International Neuroblastoma Risk Group Project. Radiology (2011) 2.35

Paraneoplastic limbic encephalitis in a teenage girl with an immature ovarian teratoma. Pediatr Radiol (2005) 2.34

Clinical assessment and management of toddlers with suspected autism spectrum disorder: insights from studies of high-risk infants. Pediatrics (2009) 2.29

Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics (2012) 2.18

Mechanism of cerebral edema in children with diabetic ketoacidosis. J Pediatr (2004) 2.15

Examining the relationship between executive functions and restricted, repetitive symptoms of Autistic Disorder. J Autism Dev Disord (2005) 2.14

Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study. Am J Clin Nutr (2012) 2.14

Current methods for reducing intussusception: survey results. Pediatr Radiol (2014) 2.03

How do rhesus monkeys ( Macaca mulatta) scan faces in a visual paired comparison task? Anim Cogn (2003) 2.01

Onset patterns in autism: correspondence between home video and parent report. J Am Acad Child Adolesc Psychiatry (2011) 1.93

Superior temporal gyrus, language function, and autism. Dev Neuropsychol (2007) 1.89

Cortical folding abnormalities in autism revealed by surface-based morphometry. J Neurosci (2007) 1.86

Frequency of sub-clinical cerebral edema in children with diabetic ketoacidosis. Pediatr Diabetes (2006) 1.86

Beyond autism: a baby siblings research consortium study of high-risk children at three years of age. J Am Acad Child Adolesc Psychiatry (2013) 1.86

Repetitive behavior profiles in Asperger syndrome and high-functioning autism. J Autism Dev Disord (2005) 1.82

The organization of projections from the amygdala to visual cortical areas TE and V1 in the macaque monkey. J Comp Neurol (2005) 1.81

Macaque monkey retrosplenial cortex: III. Cortical efferents. J Comp Neurol (2007) 1.81

Autism, regression, and the broader autism phenotype. Am J Med Genet (2002) 1.80

Stereological analysis of amygdala neuron number in autism. J Neurosci (2006) 1.75

Atypical object exploration at 12 months of age is associated with autism in a prospective sample. Autism (2008) 1.74

Brain enlargement is associated with regression in preschool-age boys with autism spectrum disorders. Proc Natl Acad Sci U S A (2011) 1.73

Amygdalectomy and responsiveness to novelty in rhesus monkeys (Macaca mulatta): generality and individual consistency of effects. Emotion (2006) 1.71

How early do parent concerns predict later autism diagnosis? J Dev Behav Pediatr (2009) 1.70

Dose reduction in pediatric CT: a rational approach. Radiology (2003) 1.70

The Ohio Patient Navigation Research Program: does the American Cancer Society patient navigation model improve time to resolution in patients with abnormal screening tests? Cancer Epidemiol Biomarkers Prev (2012) 1.66

Neural and behavioral substrates of mood and mood regulation. Biol Psychiatry (2002) 1.65

Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner. Cancer Res (2013) 1.64

Autism and family home movies: a comprehensive review. J Dev Behav Pediatr (2006) 1.63

UV light B-mediated inhibition of skin catalase activity promotes Gr-1+ CD11b+ myeloid cell expansion. J Invest Dermatol (2011) 1.61

Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical development. Psychiatry Res (2009) 1.56

Regression in autism: prevalence and associated factors in the CHARGE Study. Ambul Pediatr (2008) 1.56

Entorhinal cortex lesions disrupt the relational organization of memory in monkeys. J Neurosci (2004) 1.55

Gene expression changes in children with autism. Genomics (2007) 1.55

Behavioral profiles of affected and unaffected siblings of children with autism: contribution of measures of mother-infant interaction and nonverbal communication. J Autism Dev Disord (2011) 1.53

Multimodal imaging of the self-regulating developing brain. Proc Natl Acad Sci U S A (2012) 1.49

Relationship of EMAST and microsatellite instability among patients with rectal cancer. J Gastrointest Surg (2010) 1.48

Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4⁺ T cells from patients with GI malignancy. Cancer Immunol Immunother (2011) 1.47

Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes. J Neuroimmunol (2008) 1.41

Social skills interventions for the autism spectrum: essential ingredients and a model curriculum. Child Adolesc Psychiatr Clin N Am (2003) 1.39

Hippocampal lesion prevents spatial relational learning in adult macaque monkeys. J Neurosci (2006) 1.39

EEG sharp waves and sparse ensemble unit activity in the macaque hippocampus. J Neurophysiol (2007) 1.37

Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders. Brain Behav Immun (2008) 1.34

The relationship between executive functioning, central coherence, and repetitive behaviors in the high-functioning autism spectrum. Autism (2007) 1.34

Utility of the Gilliam Autism Rating Scale in research and clinical populations. J Autism Dev Disord (2002) 1.34

Formal thought disorder and the autism spectrum: relationship with symptoms, executive control, and anxiety. J Autism Dev Disord (2008) 1.33

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Mol Cancer (2010) 1.27

Orbital granulocytic sarcoma: an unusual presentation of acute myelocytic leukemia. Pediatr Radiol (2002) 1.26

Is maternal influenza or fever during pregnancy associated with autism or developmental delays? Results from the CHARGE (CHildhood Autism Risks from Genetics and Environment) study. J Autism Dev Disord (2013) 1.25

Long-term influence of normal variation in neonatal characteristics on human brain development. Proc Natl Acad Sci U S A (2012) 1.23

Quantitative analysis of postnatal neurogenesis and neuron number in the macaque monkey dentate gyrus. Eur J Neurosci (2010) 1.21

Brief report: methods for acquiring structural MRI data in very young children with autism without the use of sedation. J Autism Dev Disord (2007) 1.20

Gross motor development, movement abnormalities, and early identification of autism. J Autism Dev Disord (2007) 1.20

How does the topic of conversation affect verbal exchange and eye gaze? A comparison between typical development and high-functioning autism. Neuropsychologia (2010) 1.20

Increased rate of amygdala growth in children aged 2 to 4 years with autism spectrum disorders: a longitudinal study. Arch Gen Psychiatry (2012) 1.20

Imitation from 12 to 24 months in autism and typical development: a longitudinal Rasch analysis. Dev Psychol (2011) 1.19

Acoustic startle reflex in rhesus monkeys: a review. Rev Neurosci (2008) 1.18

Hippocampal volume is preserved and fails to predict recognition memory impairment in aged rhesus monkeys (Macaca mulatta). Neurobiol Aging (2005) 1.17

Investigation of neuroanatomical differences between autism and Asperger syndrome. Arch Gen Psychiatry (2004) 1.14

Correlation of clinical and biochemical findings with diabetic ketoacidosis-related cerebral edema in children using magnetic resonance diffusion-weighted imaging. J Pediatr (2008) 1.14

Bilateral neurotoxic amygdala lesions in rhesus monkeys (Macaca mulatta): consistent pattern of behavior across different social contexts. Behav Neurosci (2008) 1.12

Dissemination of evidence-based practice: can we train therapists from a distance? J Autism Dev Disord (2009) 1.12

Spatial relational learning persists following neonatal hippocampal lesions in macaque monkeys. Nat Neurosci (2006) 1.11

Effects of neonatal amygdala or hippocampus lesions on resting brain metabolism in the macaque monkey: a microPET imaging study. Neuroimage (2007) 1.11

The nonhuman primate amygdala is necessary for the acquisition but not the retention of fear-potentiated startle. Biol Psychiatry (2008) 1.10

Play and developmental outcomes in infant siblings of children with autism. J Autism Dev Disord (2010) 1.09

Secondary malignancies among nonseminomatous germ cell tumor cancer survivors. Cancer (2011) 1.09

Entorhinal cortex of the monkey: IV. Topographical and laminar organization of cortical afferents. J Comp Neurol (2008) 1.08

Stereological analysis of the rat and monkey amygdala. J Comp Neurol (2011) 1.08

Cytoplasmic estrogen receptor in breast cancer. Clin Cancer Res (2011) 1.07

Role of the primate amygdala in fear-potentiated startle: effects of chronic lesions in the rhesus monkey. J Neurosci (2007) 1.07

Synaptic organization of projections from the amygdala to visual cortical areas TE and V1 in the macaque monkey. J Comp Neurol (2006) 1.07

Functional neuroanatomy of the medial temporal lobe memory system. Cortex (2004) 1.06

A comprehensive volumetric analysis of the cerebellum in children and adolescents with autism spectrum disorder. Autism Res (2009) 1.06

Abnormal structure or function of the amygdala is a common component of neurodevelopmental disorders. Neuropsychologia (2010) 1.06

Offering to share: how to put heads together in autism neuroimaging. J Autism Dev Disord (2007) 1.05

Postnatal development of the hippocampal formation: a stereological study in macaque monkeys. J Comp Neurol (2011) 1.05