Smooth muscle hypercontractility in airway hyperresponsiveness: innate, acquired, or nonexistent?

PubWeight™: 0.75‹?›

🔗 View Article (PMC 3703427)

Published in J Allergy (Cairo) on June 17, 2013

Authors

Ynuk Bossé1, Eric Rousseau, Yassine Amrani, Michael M Grunstein

Author Affiliations

1: Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, 2725 Chemin Sainte-Foy, Québec, QC, Canada G1V 4G5.

Articles by these authors

Variants of DENND1B associated with asthma in children. N Engl J Med (2009) 4.18

Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact. FASEB J (2005) 2.13

Targeting TNF-alpha: a novel therapeutic approach for asthma. J Allergy Clin Immunol (2007) 1.80

Regulation of Toll-like receptor 4-induced proasthmatic changes in airway smooth muscle function by opposing actions of ERK1/2 and p38 MAPK signaling. Am J Physiol Lung Cell Mol Physiol (2006) 1.67

TGF-beta potentiates airway smooth muscle responsiveness to bradykinin. Am J Physiol Lung Cell Mol Physiol (2005) 1.51

ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry. J Allergy Clin Immunol (2008) 1.46

Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma. Am J Respir Crit Care Med (2014) 1.44

Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway. Am J Respir Cell Mol Biol (2004) 1.43

Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists. Am J Respir Cell Mol Biol (2002) 1.37

Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells. FASEB J (2003) 1.36

IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle. Br J Pharmacol (2003) 1.35

Functional endothelin receptors are present on nuclei in cardiac ventricular myocytes. J Biol Chem (2003) 1.30

17,18-epoxyeicosatetraenoic acid targets PPARγ and p38 mitogen-activated protein kinase to mediate its anti-inflammatory effects in the lung: role of soluble epoxide hydrolase. Am J Respir Cell Mol Biol (2009) 1.20

CD38 expression is insensitive to steroid action in cells treated with tumor necrosis factor-alpha and interferon-gamma by a mechanism involving the up-regulation of the glucocorticoid receptor beta isoform. Mol Pharmacol (2005) 1.19

Mechanisms of inflammation-mediated airway smooth muscle plasticity and airways remodeling in asthma. Respir Physiol Neurobiol (2003) 1.17

TNF-[alpha] modulates murine tracheal rings responsiveness to G-protein-coupled receptor agonists and KCl. J Appl Physiol (1985) (2003) 1.16

Cytokines induce an early steroid resistance in airway smooth muscle cells: novel role of interferon regulatory factor-1. Am J Respir Cell Mol Biol (2007) 1.16

Tumor necrosis factor alpha modulates airway smooth muscle function via the autocrine action of interferon beta. J Biol Chem (2003) 1.13

Relaxing effects of 17(18)-EpETE on arterial and airway smooth muscles in human lung. Am J Physiol Lung Cell Mol Physiol (2008) 1.11

Dietary flaxseed supplementation ameliorates inflammation and oxidative tissue damage in experimental models of acute lung injury in mice. J Nutr (2006) 1.10

Synthetic responses in airway smooth muscle. J Allergy Clin Immunol (2004) 1.09

Oxygen dose responsiveness of human fetal airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2012) 1.07

Tumor necrosis factor-alpha differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-beta-dependent CD38 pathway. Mol Pharmacol (2004) 1.05

EET displays anti-inflammatory effects in TNF-alpha stimulated human bronchi: putative role of CPI-17. Am J Respir Cell Mol Biol (2007) 1.05

Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids. FASEB J (2006) 1.03

Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness. Immunobiology (2008) 1.01

Inhibition of tumor necrosis factor-alpha-inducible inflammatory genes by interferon-gamma is associated with altered nuclear factor-kappaB transactivation and enhanced histone deacetylase activity. Mol Pharmacol (2006) 1.01

Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production. J Immunol (2009) 1.00

Functional effects of 20-HETE on human bronchi: hyperpolarization and relaxation due to BKCa channel activation. Am J Physiol Lung Cell Mol Physiol (2007) 1.00

Outcome value of Clara cell protein in serum of patients with acute respiratory distress syndrome. Intensive Care Med (2006) 0.98

Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells. Am J Respir Cell Mol Biol (2009) 0.97

Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2009) 0.96

Mechanism of glucocorticoid protection of airway smooth muscle from proasthmatic effects of long-acting beta2-adrenoceptor agonist exposure. J Allergy Clin Immunol (2010) 0.95

Autocrine regulation of airway smooth muscle responsiveness. Respir Physiol Neurobiol (2003) 0.95

Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis. Mol Pharmacol (2009) 0.95

Vascular endothelial growth factor-induced secretion of fibronectin is ERK dependent. Am J Physiol Lung Cell Mol Physiol (2003) 0.94

Cytokines alter glucocorticoid receptor phosphorylation in airway cells: role of phosphatases. Am J Respir Cell Mol Biol (2012) 0.94

20-hydroxyeicosatetraenoic acid (20-HETE) activates mouse TRPC6 channels expressed in HEK293 cells. J Biol Chem (2003) 0.94

Prolonged heterologous beta2-adrenoceptor desensitization promotes proasthmatic airway smooth muscle function via PKA/ERK1/2-mediated phosphodiesterase-4 induction. Am J Physiol Lung Cell Mol Physiol (2008) 0.93

Impact of stepwise mandibular advancement on upper airway mechanics in obstructive sleep apnea using phrenic nerve magnetic stimulation. Respir Physiol Neurobiol (2013) 0.92

Bradykinin induces interleukin-6 production in human airway smooth muscle cells: modulation by Th2 cytokines and dexamethasone. Am J Respir Cell Mol Biol (2003) 0.91

Docosahexaenoic acid derivative prevents inflammation and hyperreactivity in lung: implication of PKC-Potentiated inhibitory protein for heterotrimeric myosin light chain phosphatase of 17 kD in asthma. Am J Respir Cell Mol Biol (2010) 0.91

Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol (2004) 0.91

The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells. Respir Res (2005) 0.89

Docosapentaenoic acid monoacylglyceride reduces inflammation and vascular remodeling in experimental pulmonary hypertension. Am J Physiol Heart Circ Physiol (2014) 0.89

Th2 cytokine-induced upregulation of 11beta-hydroxysteroid dehydrogenase-1 facilitates glucocorticoid suppression of proasthmatic airway smooth muscle function. Am J Physiol Lung Cell Mol Physiol (2009) 0.86

Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is KCa3.1-dependent. Respir Res (2014) 0.86

Is airway smooth muscle the "missing link" modulating airway inflammation in asthma? Chest (2008) 0.86

Toll-like receptor 9 activation induces expression of membrane-bound B-cell activating factor (BAFF) on human B cells and leads to increased proliferation in response to both soluble and membrane-bound BAFF. Rheumatology (Oxford) (2013) 0.86

Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation. Mol Pharmacol (2007) 0.86

Airway smooth muscle cell as an inflammatory cell: lessons learned from interferon signaling pathways. Proc Am Thorac Soc (2008) 0.86

Pro-asthmatic cytokines regulate unliganded and ligand-dependent glucocorticoid receptor signaling in airway smooth muscle. PLoS One (2013) 0.86

Superantigen presentation by airway smooth muscle to CD4+ T lymphocytes elicits reciprocal proasthmatic changes in airway function. J Immunol (2007) 0.85

G Protein βγ-subunit signaling mediates airway hyperresponsiveness and inflammation in allergic asthma. PLoS One (2012) 0.85

TNF-alpha and calcium signaling in airway smooth muscle cells: a never-ending story with promising therapeutic relevance. Am J Respir Cell Mol Biol (2007) 0.85

An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma. PLoS One (2012) 0.84

Sarcoplasmic reticulum K(+) channels from human and sheep atrial cells display a specific electro-pharmacological profile. J Mol Cell Cardiol (2002) 0.84

Vitamin D attenuates cytokine-induced remodeling in human fetal airway smooth muscle cells. J Cell Physiol (2015) 0.84

20-HETE inotropic effects involve the activation of a nonselective cationic current in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2003) 0.84

19,20-EpDPE, a bioactive CYP450 metabolite of DHA monoacyglyceride, decreases Ca²⁺ sensitivity in human pulmonary arteries. Am J Physiol Heart Circ Physiol (2011) 0.82

Immunopathogenesis of severe asthma. Curr Pharm Des (2011) 0.82

Effect of short-term organoid culture on the pharmaco-mechanical properties of rat extra- and intrapulmonary arteries. Br J Pharmacol (2005) 0.82

Current concepts on the use of glucocorticosteroids and beta-2-adrenoreceptor agonists to treat childhood asthma. Curr Opin Pediatr (2010) 0.81

Improved bioavailability of epoxyeicosatrienoic acids reduces TP-receptor agonist-induced tension in human bronchi. Am J Physiol Lung Cell Mol Physiol (2011) 0.81

Basal p38 mitogen-activated protein kinase regulates unliganded glucocorticoid receptor function in airway smooth muscle cells. Am J Respir Cell Mol Biol (2014) 0.81

IL-13-induced changes in endogenous glucocorticoid metabolism in the lung regulate the proasthmatic response. Am J Physiol Lung Cell Mol Physiol (2012) 0.81

Gene expression profiling of flaxseed in mouse lung tissues-modulation of toxicologically relevant genes. BMC Complement Altern Med (2012) 0.80

Epoxyeicosatrienoic acid relaxing effects involve Ca2+-activated K+ channel activation and CPI-17 dephosphorylation in human bronchi. Am J Respir Cell Mol Biol (2007) 0.80

Effects of omega-hydroxylase product on distal human pulmonary arteries. Am J Physiol Heart Circ Physiol (2008) 0.79

Diacylglycerol-containing docosahexaenoic acid in acyl chain modulates airway smooth muscle tone. Am J Respir Cell Mol Biol (2005) 0.79

Functional reconstitution of an eicosanoid-modulated Cl- channel from bovine tracheal smooth muscle. Am J Physiol Cell Physiol (2002) 0.79

NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues. Am J Physiol Lung Cell Mol Physiol (2011) 0.79

TRPC6 silencing in primary airway smooth muscle cells inhibits protein expression without affecting OAG-induced calcium entry. Mol Cell Biochem (2006) 0.79

Counterregulation of beta(2)-adrenoceptor function in human mast cells by stem cell factor. J Allergy Clin Immunol (2009) 0.79

CPI-17 silencing-reduced responsiveness in control and TNF-alpha-treated human bronchi. Am J Respir Cell Mol Biol (2008) 0.79

Enhanced Ca2+ sensitivity in hyperresponsive cultured bronchi is mediated by TNFalpha and NF-kappaB. Can J Physiol Pharmacol (2006) 0.78

Organ-cultured airway explants: a new model of airway hyperresponsiveness. Exp Lung Res (2005) 0.78

Bronchial inflammation induced PKCζ over-expression: involvement in mechanical properties of airway smooth muscle. Can J Physiol Pharmacol (2012) 0.78

G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells. J Biomed Sci (2005) 0.78

The eSMAF: a software for the assessment and follow-up of functional autonomy in geriatrics. BMC Geriatr (2007) 0.78

Response to C3a, mast cells, and asthma. FASEB J (2006) 0.77

Consecutive transcranial magnetic stimulation twitches reduce flow limitation during sleep in apnoeic patients. Exp Physiol (2013) 0.77

8-BuS-ATP derivatives as specific NTPDase1 inhibitors. Br J Pharmacol (2013) 0.77

Why eicosanoids could represent a new class of tocolytics on uterine activity in pregnant women. Am J Obstet Gynecol (2009) 0.76

Relaxing effects of 5-oxo-ETE on human bronchi involve BK Ca channel activation. Prostaglandins Other Lipid Mediat (2007) 0.76

T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta. J Allergy Clin Immunol (2002) 0.76

Docosahexaenoic acid monoacylglyceride decreases endothelin-1 induced Ca(2+) sensitivity and proliferation in human pulmonary arteries. Am J Hypertens (2012) 0.76

"Pas de DEux" for phosphodiesterase-2 in acute lung injury. Crit Care Med (2009) 0.75

Concentration- and time-dependent effects of enoxaparin on human adenocarcinomic epithelial cell line A549 proliferation in vitro. Can J Physiol Pharmacol (2011) 0.75

Effects of one-week tongue task training on sleep apnea severity: A pilot study. Can Respir J (2015) 0.75

Effect of cytochrome P-450 epoxygenase and hydroxylase metabolites on rat myometrium contractility in non-pregnancy, late pregnancy and late pregnancy under inflammatory conditions. J Obstet Gynaecol Res (2013) 0.75

Diaphragm and genioglossus corticomotor excitability in patients with obstructive sleep apnea and control subjects. J Sleep Res (2016) 0.75

5-Oxo-ETE regulates tone of guinea pig airway smooth muscle via activation of Ca2+ pools and Rho-kinase pathway. Am J Physiol Lung Cell Mol Physiol (2004) 0.75

Inhibition of epoxy-eicosanoid degradation improves the tocolytic effects of indomethacin in the uterus from pregnant women. Prostaglandins Other Lipid Mediat (2011) 0.75

Lipoxygenase and cyclooxygenase inhibitors reveal a complementary role of arachidonic acid derivatives in pregnant human myometrium. Am J Obstet Gynecol (2010) 0.75

Effects of 5-oxo-ETE and 14,15-EET on reactivity and Ca2+ sensitivity in guinea pig bronchi. Prostaglandins Other Lipid Mediat (2006) 0.75