Covert operations: cancer's many subversive tactics in overcoming host defenses.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 3715908)

Published in Trans Am Clin Climatol Assoc on January 01, 2013

Authors

Dan L Longo1

Author Affiliations

1: dlongo@nejm.org

Articles cited by this

Natural innate and adaptive immunity to cancer. Annu Rev Immunol (2011) 7.09

Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice. Science (1992) 5.94

L-arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes. J Immunol (2003) 2.91

Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma. Cancer Res (1993) 2.01

Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res (1993) 1.95

Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain. J Clin Invest (1998) 1.80

Sustained exposure to bacterial antigen induces interferon-gamma-dependent T cell receptor zeta down-regulation and impaired T cell function. Nat Immunol (2003) 1.80

Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity. Eur J Immunol (1996) 1.51

Treatment of cancer patients with ex vivo anti-CD3-activated killer cells and interleukin-2. J Clin Oncol (1993) 1.46

Alterations in T cell receptor and signal transduction molecules in melanoma patients. Clin Cancer Res (1995) 1.33

Prolonged exposure of T cells to TNF down-regulates TCR zeta and expression of the TCR/CD3 complex at the cell surface. J Immunol (2001) 1.25

Clinical significance of decreased zeta chain expression in peripheral blood lymphocytes of patients with head and neck cancer. Clin Cancer Res (1999) 1.17

Immunotherapy for metastatic solid cancers. Adv Surg (2011) 1.16

Changes in expression of signal transduction proteins in T lymphocytes of patients with leprosy. Infect Immun (1998) 1.10

Decreased expression of signal-transducing zeta chain in peripheral T cells and natural killer cells in patients with cervical cancer. Clin Cancer Res (1996) 1.08

Sequential development of structural and functional alterations in T cells from tumor-bearing mice. J Immunol (1997) 1.05

HIV infection--induced posttranslational modification of T cell signaling molecules associated with disease progression. J Clin Invest (1996) 1.02

Absent or low expression of the zeta chain in T cells at the tumor site correlates with poor survival in patients with oral carcinoma. Cancer Res (1998) 0.99

The dendritic cell-regulatory T lymphocyte crosstalk contributes to tumor-induced tolerance. Clin Dev Immunol (2011) 0.99

Immunoregulation in cancer-bearing hosts. Down-regulation of gene expression and cytotoxic function in CD8+ T cells. J Immunol (1992) 0.92

Neoplastic "Black Ops": cancer's subversive tactics in overcoming host defenses. Semin Cancer Biol (2012) 0.92

Gradual loss of T-helper 1 populations in spleen of mice during progressive tumor growth. J Natl Cancer Inst (1995) 0.92

Modulation of T-cell CD3-zeta chain expression during normal pregnancy. J Reprod Immunol (2002) 0.91

Tumor-dependent down-regulation of the ζ-chain in T-cells is detectable in early breast cancer and correlates with immune cell function. Int J Cancer (2011) 0.90

Modulation of TcR/CD3-zeta chain expression by a circulating factor derived from ovarian cancer patients. Br J Cancer (2001) 0.90

Alterations in NF kappa B/Rel family proteins in splenic T-cells from tumor-bearing mice and reversal following therapy. Cancer Res (1994) 0.90

The history of the development of vaccines for the treatment of lymphoma. Clin Lymphoma (2000) 0.84

Expression of signal-transducing zeta chain in peripheral blood T cells and natural killer cells in patients with Hodgkin's disease in different phases of the disease. Leuk Lymphoma (1999) 0.84

Alterations in the expression of signal-transducing CD3 zeta chain in T cells from patients with chronic inflammatory/autoimmune diseases. Arch Immunol Ther Exp (Warsz) (2007) 0.82

Decreased CD3+CD16+ natural killer-like T-cell percentage and zeta-chain expression accompany chronic inflammation in haemodialysis patients. Nephrology (Carlton) (2009) 0.81

Antitumor effects of interleukin 2 liposomes and anti-CD3-stimulated T-cells against murine MCA-38 hepatic metastasis. Cancer Res (1991) 0.81