Mesenchymal stem cells in joint disease and repair.

PubWeight™: 1.31‹?› | Rank: Top 10%

🔗 View Article (PMID 23881068)

Published in Nat Rev Rheumatol on July 23, 2013

Authors

Frank Barry1, Mary Murphy

Author Affiliations

1: Regenerative Medicine Institute, National Centre for Biomedical Engineering Science, National University of Ireland Galway, University Road, Galway, Ireland.

Associated clinical trials:

ADIPOA - Clinical Study | NCT01585857

Treatment of Knee Osteoarthritis With Allogenic Mesenchymal Stem Cells (MSV_allo) | NCT01586312

Study to Compare the Efficacy and Safety of Cartistem® and Microfracture in Patients With Knee Articular Cartilage Injury or Defect | NCT01041001

Autologous Adipose Tissue Derived Mesenchymal Stem Cells Transplantation in Patient With Degenerative Arthritis | NCT01300598

Intra-Articular Autologous Bone Marrow Mesenchymal Stem Cells Transplantation to Treat Mild to Moderate Osteoarthritis | NCT01459640

Adult Stem Cell Therapy for Repairing Articular Cartilage in Gonarthrosis | NCT01227694

Allogeneic Mesenchymal Stem Cells in Osteoarthritis | NCT01453738

Transplantation of Bone Marrow Stem Cells Stimulated by Proteins Scaffold to Heal Defects Articular Cartilage of the Knee | NCT01159899

Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells (KDD&MSV) | NCT01183728

Side Effects of Autologous Mesenchymal Stem Cell Transplantation in Ankle Joint Osteoartritis | NCT01436058

The Effects of Intra-articular Injection of Mesenchymal Stem Cells in Knee Joint Osteoarthritis | NCT01504464

Safety and Efficacy Study of MSB-CAR001 in Subjects 6 Weeks Post an Anterior Cruciate Ligament Reconstruction | NCT01088191

Mesenchymal Stem Cell Transplantation in Osteoarthritis of Hip Joint | NCT01499056

Follow-Up Study of CARTISTEM® Versus Microfracture for the Treatment of Knee Articular Cartilage Injury or Defect | NCT01626677

Articles citing this

Progress in intra-articular therapy. Nat Rev Rheumatol (2013) 1.24

Mesenchymal stem cells, autoimmunity and rheumatoid arthritis. QJM (2014) 1.04

Current concepts: the role of mesenchymal stem cells in the management of knee osteoarthritis. Sports Health (2015) 0.90

Future directions for the management of pain in osteoarthritis. Int J Clin Rheumtol (2014) 0.89

Tracking gene and cell fate for therapeutic gain. Nat Mater (2014) 0.88

Current perspectives in mesenchymal stem cell therapies for osteoarthritis. Stem Cells Int (2014) 0.88

Mesenchymal Stem Cell Alterations in Bone Marrow Lesions in Patients With Hip Osteoarthritis. Arthritis Rheumatol (2016) 0.86

Therapeutic Potential of Differentiated Mesenchymal Stem Cells for Treatment of Osteoarthritis. Int J Mol Sci (2015) 0.84

Single cell sorting identifies progenitor cell population from full thickness bovine articular cartilage. Osteoarthritis Cartilage (2014) 0.84

Are mesenchymal stem cells in rheumatoid arthritis the good or bad guys? Arthritis Res Ther (2015) 0.83

Radio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinic. Oncotarget (2015) 0.82

Synovial fluid and synovial membrane mesenchymal stem cells: latest discoveries and therapeutic perspectives. Stem Cell Res Ther (2014) 0.82

Mesenchymal stem cell therapy in the treatment of osteoarthritis: reparative pathways, safety and efficacy - a review. BMC Musculoskelet Disord (2016) 0.80

Acquiring chondrocyte phenotype from human mesenchymal stem cells under inflammatory conditions. Int J Mol Sci (2014) 0.80

Vascular remodeling underlies rebleeding in hemophilic arthropathy. Am J Hematol (2015) 0.80

Derivation of mesenchymal stromal cells from canine induced pluripotent stem cells by inhibition of the TGFβ/activin signaling pathway. Stem Cells Dev (2014) 0.80

Mesenchymal stem cell therapy for osteoarthritis: current perspectives. Stem Cells Cloning (2015) 0.79

Efficacy of mesenchymal stem cells in treating patients with osteoarthritis of the knee: A meta-analysis. Exp Ther Med (2016) 0.78

Tracking of mesenchymal stem cells labeled with gadolinium diethylenetriamine pentaacetic acid by 7T magnetic resonance imaging in a model of cerebral ischemia. Mol Med Rep (2014) 0.78

Adipose, Bone Marrow and Synovial Joint-Derived Mesenchymal Stem Cells for Cartilage Repair. Front Genet (2016) 0.77

Adipose-derived mesenchymal stem cells and platelet-rich plasma synergistically ameliorate the surgical-induced osteoarthritis in Beagle dogs. J Orthop Surg Res (2016) 0.77

Allogeneic Bone Marrow Transplant from MRL/MpJ Super-Healer Mice Does Not Improve Articular Cartilage Repair in the C57Bl/6 Strain. PLoS One (2015) 0.77

Stem cells for the treatment of musculoskeletal pain. World J Stem Cells (2015) 0.77

Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cell, Leading to Bohring-Opitz-like Syndrome in Mice. Stem Cell Reports (2016) 0.76

Intrinsic multipotential mesenchymal stromal cell activity in gelatinous Heberden's nodes in osteoarthritis at clinical presentation. Arthritis Res Ther (2014) 0.76

Whole-Genome Expression Analysis and Signal Pathway Screening of Synovium-Derived Mesenchymal Stromal Cells in Rheumatoid Arthritis. Stem Cells Int (2016) 0.75

Human Articular Chondrocytes Regulate Immune Response by Affecting Directly T Cell Proliferation and Indirectly Inhibiting Monocyte Differentiation to Professional Antigen-Presenting Cells. Front Immunol (2016) 0.75

Editor's Spotlight/Take 5: Adipose-derived Mesenchymal Stem Cells Are Phenotypically Superior for Regeneration in the Setting of Osteonecrosis of the Femoral Head. Clin Orthop Relat Res (2015) 0.75

Mechanical loading inhibits hypertrophy in chondrogenically differentiating hMSCs within a biomimetic hydrogel. J Mater Chem B Mater Biol Med (2016) 0.75

The Therapeutic Effect of Adipose-Derived Mesenchymal Stem Cells for Radiation-Induced Bladder Injury. Stem Cells Int (2016) 0.75

Use of FGF-2 and FGF-18 to direct bone marrow stromal stem cells to chondrogenic and osteogenic lineages. Future Sci OA (2016) 0.75

Optimized Stem Cell Detection Using the DyeCycle-Triggered Side Population Phenotype. Stem Cells Int (2015) 0.75

Promotion of in vivo degradability, vascularization and osteogenesis of calcium sulfate-based bone cements containing nanoporous lithium doping magnesium silicate. Int J Nanomedicine (2017) 0.75

Bright Polymer Dots Tracking Stem Cell Engraftment and Migration to Injured Mouse Liver. Theranostics (2017) 0.75

The Functions of BMP3 in Rabbit Articular Cartilage Repair. Int J Mol Sci (2015) 0.75

Additional mesenchymal stem cell injection improves the outcomes of marrow stimulation combined with supramalleolar osteotomy in varus ankle osteoarthritis: short-term clinical results with second-look arthroscopic evaluation. J Exp Orthop (2016) 0.75

Mesenchymal stem cells for cartilage regeneration in osteoarthritis. World J Orthop (2017) 0.75

The Holy Grail of Orthopedic Surgery: Mesenchymal Stem Cells-Their Current Uses and Potential Applications. Stem Cells Int (2017) 0.75

Mitochondrial DNA Hypomethylation Is a Biomarker Associated with Induced Senescence in Human Fetal Heart Mesenchymal Stem Cells. Stem Cells Int (2017) 0.75

[Therapeutic utilization of stem cells in orthopedics]. Orthopade (2017) 0.75

Articles cited by this

(truncated to the top 100)

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy (2006) 37.55

Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am (2007) 24.18

Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum (2008) 19.80

A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell (2008) 18.18

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature (2010) 15.28

Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell (2007) 10.13

Adipose-derived stem cells for regenerative medicine. Circ Res (2007) 7.68

The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinet (1970) 7.16

Mesenchymal stem cells: revisiting history, concepts, and assays. Cell Stem Cell (2008) 6.26

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature (2005) 5.71

Mesenchymal stem cells: clinical applications and biological characterization. Int J Biochem Cell Biol (2004) 5.43

Stromal stem cells: marrow-derived osteogenic precursors. Ciba Found Symp (1988) 4.94

Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration. Cell Stem Cell (2012) 4.67

Multipotent mesenchymal stem cells from adult human synovial membrane. Arthritis Rheum (2001) 4.57

Osteogenesis in transplants of bone marrow cells. J Embryol Exp Morphol (1966) 4.55

Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo. Transplantation (1974) 4.26

Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source. Arthritis Rheum (2005) 4.25

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature (2005) 4.24

The impact of osteoarthritis: implications for research. Clin Orthop Relat Res (2004) 3.63

Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage. J Bone Joint Surg Am (1994) 3.62

Stem cell therapy in a caprine model of osteoarthritis. Arthritis Rheum (2003) 3.39

The surface of articular cartilage contains a progenitor cell population. J Cell Sci (2004) 3.28

Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study. Lancet (2010) 3.26

Synovial tissue inflammation in early and late osteoarthritis. Ann Rheum Dis (2005) 3.25

A stem cell-based approach to cartilage repair. Science (2012) 3.22

Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo. J Cell Physiol (2008) 3.13

All MSCs are pericytes? Cell Stem Cell (2008) 3.12

Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. Nature (2011) 3.03

Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease. Stem Cells (2005) 2.74

Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis. Ann N Y Acad Sci (2010) 2.73

Synovitis: a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis -- results of a 1 year longitudinal arthroscopic study in 422 patients. Osteoarthritis Cartilage (2005) 2.69

Migratory chondrogenic progenitor cells from repair tissue during the later stages of human osteoarthritis. Cell Stem Cell (2009) 2.48

Wharton's jelly-derived cells are a primitive stromal cell population. Stem Cells (2007) 2.46

Assessing the burden of disease in the United States using disability-adjusted life years. Am J Prev Med (2005) 2.40

The burden of disease and injury in the United States 1996. Popul Health Metr (2006) 2.27

Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury. Nat Med (2012) 2.24

Identification of mesenchymal progenitor cells in normal and osteoarthritic human articular cartilage. Arthritis Rheum (2004) 2.23

Reduced chondrogenic and adipogenic activity of mesenchymal stem cells from patients with advanced osteoarthritis. Arthritis Rheum (2002) 2.20

Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and Is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism. Biochem Biophys Res Commun (1999) 2.18

Synovial fluid-derived mesenchymal stem cells increase after intra-articular ligament injury in humans. Rheumatology (Oxford) (2008) 2.11

A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis. Dev Biol (2008) 2.09

Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain. J Biol Chem (1991) 2.02

Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane. J Cell Biol (2003) 1.99

Intra-articular injection of human mesenchymal stem cells (MSCs) promote rat meniscal regeneration by being activated to express Indian hedgehog that enhances expression of type II collagen. Osteoarthritis Cartilage (2012) 1.96

Enumeration and phenotypic characterization of synovial fluid multipotential mesenchymal progenitor cells in inflammatory and degenerative arthritis. Arthritis Rheum (2004) 1.89

Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis. Arthritis Res Ther (2009) 1.82

Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis. Arthritis Res Ther (2012) 1.74

Osteoarthritis. Adv Drug Deliv Rev (2006) 1.73

Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age. Arthritis Rheum (2001) 1.69

Stem cells in the umbilical cord. Stem Cell Rev (2006) 1.63

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review. Osteoarthritis Cartilage (2012) 1.62

Biomechanical factors in osteoarthritis. Best Pract Res Clin Rheumatol (2011) 1.56

Synovial fluid mesenchymal stem cells in health and early osteoarthritis: detection and functional evaluation at the single-cell level. Arthritis Rheum (2008) 1.55

Evaluation of adipose-derived stromal vascular fraction or bone marrow-derived mesenchymal stem cells for treatment of osteoarthritis. J Orthop Res (2009) 1.55

Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage. PLoS One (2010) 1.50

Chondrogenic potential of human adult mesenchymal stem cells is independent of age or osteoarthritis etiology. Stem Cells (2007) 1.39

Mesenchymal stem cells derived from synovium, meniscus, anterior cruciate ligament, and articular chondrocytes share similar gene expression profiles. J Orthop Res (2009) 1.37

Human mesenchymal stem cells in synovial fluid increase in the knee with degenerated cartilage and osteoarthritis. J Orthop Res (2011) 1.35

Synovium-derived mesenchymal stem cells: a new cell source for musculoskeletal regeneration. Tissue Eng Part B Rev (2009) 1.34

Functional mesenchymal stem cell niches in adult mouse knee joint synovium in vivo. Arthritis Rheum (2011) 1.33

Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritis. Arthritis Rheum (2012) 1.31

Identification of subpopulations with characteristics of mesenchymal progenitor cells from human osteoarthritic cartilage using triple staining for cell surface markers. Arthritis Res Ther (2004) 1.30

Culture and characterization of human bone marrow mesenchymal stem cells. Methods Mol Med (2007) 1.30

Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis. J Bone Miner Res (2005) 1.24

Cartilage cell clusters. Arthritis Rheum (2010) 1.21

The vascular wall as a source of stem cells. Ann N Y Acad Sci (2005) 1.20

Repair of large full-thickness articular cartilage defects with allograft articular chondrocytes embedded in a collagen gel. Tissue Eng (1998) 1.18

Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor beta-induced osteophytes: limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation. Arthritis Rheum (2007) 1.17

Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease. Proc Natl Acad Sci U S A (2005) 1.16

Adipose-derived cells. Cell Transplant (2007) 1.16

UC blood-derived mesenchymal stromal cells: an overview. Cytotherapy (2007) 1.16

Differentiation of adipose stem cells. Methods Mol Biol (2008) 1.15

Large-scale extraction and characterization of CD271+ multipotential stromal cells from trabecular bone in health and osteoarthritis: implications for bone regeneration strategies based on uncultured or minimally cultured multipotential stromal cells. Arthritis Rheum (2010) 1.14

Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling. Arthritis Res Ther (2007) 1.12

Mesenchymal progenitor cells in adult human articular cartilage. Biorheology (2006) 1.12

Production of canine mesenchymal stem cells from adipose tissue and their application in dogs with chronic osteoarthritis of the humeroradial joints. Cell Biol Int (2012) 1.11

Inhibition of cellular senescence by developmentally regulated FGF receptors in mesenchymal stem cells. Blood (2011) 1.10

Chondrogenic differentiation of mesenchymal stem cells isolated from patients in late adulthood: the optimal conditions of growth factors. Tissue Eng (2006) 1.10

Age-dependent alteration of TGF-β signalling in osteoarthritis. Cell Tissue Res (2011) 1.10

Isolation and characterization of multipotent stem cells from human cruciate ligaments. Cell Prolif (2009) 1.09

Mesenchymal stem cell characteristics of human anterior cruciate ligament outgrowth cells. Tissue Eng Part A (2011) 1.08

Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival. Oncogene (2008) 1.07

Abnormal expression of Col X, PTHrP, TGF-beta, bFGF, and VEGF in cartilage with Kashin-Beck disease. J Bone Miner Metab (2006) 1.06

Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis. Cell Transplant (2012) 1.05

Distinct mesenchymal progenitor cell subsets in the adult human synovium. Rheumatology (Oxford) (2009) 1.05

The potential of intra-articular injection of chondrogenic-induced bone marrow stem cells to retard the progression of osteoarthritis in a sheep model. Exp Gerontol (2012) 1.02

Synovial fluid CD34⁻ CD44⁺ CD90⁺ mesenchymal stem cell levels are associated with the severity of primary knee osteoarthritis. Osteoarthritis Cartilage (2011) 1.01

Knockout of ADAMTS5 does not eliminate cartilage aggrecanase activity but abrogates joint fibrosis and promotes cartilage aggrecan deposition in murine osteoarthritis models. J Orthop Res (2010) 1.01

Adamts5 deletion blocks murine dermal repair through CD44-mediated aggrecan accumulation and modulation of transforming growth factor β1 (TGFβ1) signaling. J Biol Chem (2011) 1.01

Clinical comorbidities, treatment patterns, and direct medical costs of patients with osteoarthritis in usual care: a retrospective claims database analysis. J Med Econ (2011) 0.99

Clonal chondroprogenitors maintain telomerase activity and Sox9 expression during extended monolayer culture and retain chondrogenic potential. Osteoarthritis Cartilage (2008) 0.95

The migration of cells from the ruptured human anterior cruciate ligament into collagen-glycosaminoglycan regeneration templates in vitro. Biomaterials (2001) 0.95

Articular cartilage repair with autologous bone marrow mesenchymal cells. J Cell Physiol (2010) 0.94

Cell outgrowth from the human ACL in vitro: regional variation and response to TGF-beta1. J Orthop Res (2002) 0.87

Isolation and characterization of mesenchymal stromal cells from human anterior cruciate ligament. Cytotherapy (2008) 0.87

The contribution of human synovial stem cells to skeletal muscle regeneration. Neuromuscul Disord (2010) 0.87

If good things come from above, do bad things come from below? Arthritis Res Ther (2010) 0.87

The relationship between fibrogenic TGFβ1 signaling in the joint and cartilage degradation in post-injury osteoarthritis. Osteoarthritis Cartilage (2011) 0.86

Scaffold-free adipose-derived stem cells (ASCs) improve experimentally induced osteoarthritis in rabbits. Arch Iran Med (2012) 0.86

Fat pad-derived mesenchymal stem cells as a potential source for cell-based adipose tissue repair strategies. Cell Prolif (2012) 0.85

Articles by these authors

The influence of bacterial vaginosis on the response to Trichomonas vaginalis treatment among HIV-infected women. Sex Transm Infect (2011) 2.19

Herpes simplex virus type 1 DNA-packaging protein UL17 is required for efficient binding of UL25 to capsids. J Virol (2006) 1.50

Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment. Stem Cells (2008) 1.45

The herpes simplex virus type 1 DNA packaging protein UL17 is a virion protein that is present in both the capsid and the tegument compartments. J Virol (2005) 1.32

Immunogenicity of allogeneic mesenchymal stem cells. J Cell Mol Med (2012) 1.32

Characterization of a collection of Enterobacter sakazakii isolates from environmental and food sources. Int J Food Microbiol (2006) 1.22

Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells. Int J Cancer (2009) 1.17

Carbon nanotubes and mesenchymal stem cells: biocompatibility, proliferation and differentiation. Nano Lett (2008) 1.11

Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling. J Virol (2009) 1.08

Recruitment of infants with sickle cell anemia to a Phase III trial: data from the BABY HUG study. Contemp Clin Trials (2010) 1.07

Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia. Stem Cell Res Ther (2011) 1.06

Type II collagen-hyaluronan hydrogel--a step towards a scaffold for intervertebral disc tissue engineering. Eur Cell Mater (2010) 1.02

Inhibition of human cytomegalovirus DNA polymerase by C-terminal peptides from the UL54 subunit. J Virol (2003) 1.01

Adeno-associated viral vector transduction of human mesenchymal stem cells. Eur Cell Mater (2007) 1.01

Practice makes perfect? The role of simulation-based deliberate practice and script-based mental rehearsal in the acquisition and maintenance of operative neurosurgical skills. Neurosurgery (2013) 0.99

Topical administration of allogeneic mesenchymal stromal cells seeded in a collagen scaffold augments wound healing and increases angiogenesis in the diabetic rabbit ulcer. Diabetes (2013) 0.95

Disparities in access to over-the-counter nicotine replacement products in New York City pharmacies. Am J Public Health (2009) 0.94

A matrix reservoir for improved control of non-viral gene delivery. J Control Release (2009) 0.94

Response of mesenchymal stem cells to the biomechanical environment of the endothelium on a flexible tubular silicone substrate. Biomaterials (2008) 0.92

Mutational analysis of the herpes simplex virus type 1 UL25 DNA packaging protein reveals regions that are important after the viral DNA has been packaged. J Virol (2010) 0.91

Stem cells are resistant to TRAIL receptor-mediated apoptosis. J Cell Mol Med (2010) 0.89

von Willebrand factor (VWF) propeptide binding to VWF D'D3 domain attenuates platelet activation and adhesion. Blood (2012) 0.89

Enhanced lipoplex-mediated gene expression in mesenchymal stem cells using reiterated nuclear localization sequence peptides. J Gene Med (2010) 0.87

A case of bovine raw milk contamination with Listeria monocytogenes. Ir Vet J (2012) 0.86

Adiposity of elderly women and its relationship with self-reported and observed physical performance. J Geriatr Phys Ther (2005) 0.86

Preclinical rationale for combining an EGFR antibody with cisplatin/gemcitabine for the treatment of NSCLC. Cancer Genomics Proteomics (2012) 0.86

Strategies for improved targeting of therapeutic cells: implications for tissue repair. Eur Cell Mater (2012) 0.85

In-line milk filter analysis: Escherichia coli O157 surveillance of milk production holdings. Int J Hyg Environ Health (2005) 0.85

Six months later: The effect of Hurricane Katrina on health care for persons living with HIV/AIDS in New Orleans. AIDS Care (2006) 0.85

Management of infratentorial subdural hygroma complicating foramen magnum decompression: a report of three cases. Acta Neurochir (Wien) (2011) 0.83

Bolus delivery of mesenchymal stem cells to injured vasculature in the rabbit carotid artery produces a dysfunctional endothelium. Tissue Eng Part A (2010) 0.83

Allogeneic murine mesenchymal stem cells: migration to inflamed joints in vivo and amelioration of collagen induced arthritis when transduced to express CTLA4Ig. Stem Cells Dev (2013) 0.82

Behavior of human mesenchymal stem cells in fibrin-based vascular tissue engineering constructs. Ann Biomed Eng (2010) 0.82

Paediatric and adult vascular intracranial complications of sickle-cell disease. Acta Neurochir (Wien) (2010) 0.81

Understanding of visual attention by adult humans (Homo sapiens): a partial replication of Povinelli, Bierschwale, and Cech (1999). J Comp Psychol (2008) 0.79

Safety determination for the use of bovine milk-derived lactoferrin as a component of an antimicrobial beef carcass spray. Regul Toxicol Pharmacol (2004) 0.77

Time spent moving is related to systolic blood pressure among older women. Prev Cardiol (2005) 0.76

The management of subarachnoid haemorrhage in London. Br J Neurosurg (2011) 0.75

Jedi Public Health: Co-creating an Identity-Safe Culture to Promote Health Equity. SSM Popul Health (2016) 0.75

Anti-idiotypic monobodies derived from a fibronectin scaffold. Biochemistry (2013) 0.75

Management of acute hydrocephalus following aneurysmal subarachnoid haemorrhage: the role of serial lumbar puncture and continuous lumbar drainage. Br J Neurosurg (2011) 0.75

History of neurosurgery at the Royal Free Hospital in London. Br J Neurosurg (2014) 0.75

841 Maximal Resection of Low-grade Intrinsic Brain Tumors Using "Awake" Craniotomy and Multiple Marginal Smear Biopsies: Operative Complication Rates and 10-year Survival Data. Neurosurgery (2005) 0.75

Oral hygiene in the elderly: a quality improvement initiative. Nurs Leadersh (Tor Ont) (2003) 0.75

How is block time reviewed and revised? Part 3. OR Manager (2003) 0.75

Lotus after cesarean. Midwifery Today Int Midwife (2005) 0.75

Fever and headache in an intravenous drug user. J La State Med Soc (2005) 0.75

Artefactual computed tomographic middle cerebral artery territory infarct. Br J Neurosurg (2006) 0.75

Words of wisdom: OR leaders offer tips for new managers. OR Manager (2013) 0.75

Living-donor kidney transplantation at Mayo Clinic--Rochester. Clin Transpl (2002) 0.75

Non-contiguous multifocal Staphylococcus aureus discitis: involvement of the cervical, thoracic and lumbar spine. Acta Neurochir (Wien) (2009) 0.75

A case of florid intracerebral reaction to haematoma mimicking a tumour. Br J Neurosurg (2012) 0.75

Spontaneous resolution of a symptomatic synovial cyst of the lumbar spine. Br J Neurosurg (2011) 0.75

How can ORs best manage block time for scheduling surgical cases? OR Manager (2003) 0.75

What are best ways to handle block-time release? OR Manager (2003) 0.75

Development of a modelled anatomical replica for training young neurosurgeons. Br J Neurosurg (2014) 0.75

Grip strength norms for elderly women. Percept Mot Skills (2004) 0.75