Published in Virol J on July 25, 2013
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections. Emerg Microbes Infect (2014) 0.96
A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence. J Virol (2014) 0.90
Deep sequencing reveals the eight facets of the influenza A/HongKong/1/1968 (H3N2) virus cap-snatching process. Sci Rep (2014) 0.86
Mammalian adaptive mutations of the PA protein of highly pathogenic avian H5N1 influenza virus. J Virol (2015) 0.80
Identification of adaptive mutations in the influenza A virus non-structural 1 gene that increase cytoplasmic localization and differentially regulate host gene expression. PLoS One (2013) 0.80
Survival analysis of infected mice reveals pathogenic variations in the genome of avian H1N1 viruses. Sci Rep (2014) 0.79
Structural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I. Structure (2015) 0.78
Identification of PB2 mutations responsible for the efficient replication of H5N1 influenza viruses in human lung epithelial cells. J Virol (2015) 0.78
Fluorescence-Activated Cell Sorting-Based Analysis Reveals an Asymmetric Induction of Interferon-Stimulated Genes in Response to Seasonal Influenza A Virus. J Virol (2015) 0.76
A Phospho-SIM in the Antiviral Protein PML is Required for Its Recruitment to HSV-1 Genomes. Cells (2014) 0.76
Appearance of L90I and N205S Mutations in Effector Domain of NS1 Gene of pdm (09) H1N1 Virus from India during 2009-2013. Adv Virol (2014) 0.75
Interferon Lambda: Modulating Immunity in Infectious Diseases. Front Immunol (2017) 0.75
Evidence-based translation for the genomic responses of murine models for the study of human immunity. PLoS One (2015) 0.75
Molecular determinants of influenza virus pathogenesis in mice. Curr Top Microbiol Immunol (2014) 0.75
H5N1 influenza virulence, pathogenicity and transmissibility: what do we know? Future Virol (2015) 0.75
Amino acid substitution K186E in the canine influenza virus H3N8 NS1 protein restores its ability to inhibit host gene expression. J Virol (2017) 0.75
Structure-Guided Functional Annotation of the Influenza A Virus NS1 Protein Reveals Dynamic Evolution of the p85β-Binding Site During Circulation in Humans. J Virol (2017) 0.75
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res (2002) 76.95
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol (2004) 26.12
Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med (2013) 24.88
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science (2006) 16.00
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat Med (2006) 14.21
Airborne transmission of influenza A/H5N1 virus between ferrets. Science (2012) 13.48
Lethal H5N1 influenza viruses escape host anti-viral cytokine responses. Nat Med (2002) 9.47
Cell type-specific involvement of RIG-I in antiviral response. Immunity (2005) 9.37
Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? Lancet (2002) 8.70
Molecular characterization of H9N2 influenza viruses: were they the donors of the "internal" genes of H5N1 viruses in Hong Kong? Proc Natl Acad Sci U S A (1999) 8.62
The multifunctional NS1 protein of influenza A viruses. J Gen Virol (2008) 6.87
Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein. J Virol (2000) 6.22
Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses. Lancet (2013) 6.10
Permissive secondary mutations enable the evolution of influenza oseltamivir resistance. Science (2010) 5.94
Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs. Mol Cell (1998) 5.60
Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon. J Virol (2000) 5.44
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe (2009) 5.12
A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection. Cell (2009) 4.98
Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus. J Virol (2006) 4.88
Genetic analysis of novel avian A(H7N9) influenza viruses isolated from patients in China, February to April 2013. Euro Surveill (2013) 4.44
Characterization of the pathogenicity of members of the newly established H9N2 influenza virus lineages in Asia. Virology (2000) 4.37
Pathology of fatal human infection associated with avian influenza A H5N1 virus. J Med Virol (2001) 4.08
A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity. Proc Natl Acad Sci U S A (2008) 3.99
Multiple anti-interferon actions of the influenza A virus NS1 protein. J Virol (2007) 3.53
The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway. Proc Natl Acad Sci U S A (2006) 3.50
The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A). J Virol (1994) 3.48
Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery. EMBO J (1999) 3.35
Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport. EMBO J (1994) 3.26
TLR signaling. Curr Top Microbiol Immunol (2006) 3.22
The NS1 gene contributes to the virulence of H5N1 avian influenza viruses. J Virol (2006) 3.03
Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA. Virology (2006) 3.00
A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice. J Virol (2007) 2.80
Binding of influenza A virus NS1 protein to dsRNA in vitro. J Gen Virol (1992) 2.60
Influenza virus targets the mRNA export machinery and the nuclear pore complex. Proc Natl Acad Sci U S A (2007) 2.44
Prevalence of epistasis in the evolution of influenza A surface proteins. PLoS Genet (2011) 2.41
A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis. Virology (2007) 2.30
Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: identification of functional themes. Proc Natl Acad Sci U S A (2001) 2.25
Human influenza virus A/HongKong/156/97 (H5N1) infection. Vaccine (1998) 2.17
Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs. J Virol (1995) 2.16
Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses. J Gen Virol (2005) 2.15
The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors. J Virol (2002) 2.14
The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target. J Virol (2006) 2.05
Regulation of a nuclear export signal by an adjacent inhibitory sequence: the effector domain of the influenza virus NS1 protein. Proc Natl Acad Sci U S A (1998) 1.94
A naturally occurring deletion in its NS gene contributes to the attenuation of an H5N1 swine influenza virus in chickens. J Virol (2007) 1.80
REAP: A two minute cell fractionation method. BMC Res Notes (2010) 1.76
The H5N1 influenza virus NS genes selected after 1998 enhance virus replication in mammalian cells. J Virol (2007) 1.75
PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexes. J Gen Virol (2003) 1.65
The role of compensatory mutations in the emergence of drug resistance. PLoS Comput Biol (2006) 1.63
Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein. PLoS Pathog (2012) 1.43
Nuclear export signal consensus sequences defined using a localization-based yeast selection system. Traffic (2008) 1.36
A fatal case caused by novel H7N9 avian influenza A virus in China. Emerg Microbes Infect (2013) 1.34
Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling. PLoS One (2010) 1.29
Simplified recombinational approach for influenza A virus reverse genetics. J Virol Methods (2008) 1.24
PB2 and hemagglutinin mutations are major determinants of host range and virulence in mouse-adapted influenza A virus. J Virol (2010) 1.21
Full restoration of viral fitness by multiple compensatory co-mutations in the nucleoprotein of influenza A virus cytotoxic T-lymphocyte escape mutants. J Gen Virol (2005) 1.17
Nuclear localization signals and human disease. IUBMB Life (2009) 1.15
The virulence of 1997 H5N1 influenza viruses in the mouse model is increased by correcting a defect in their NS1 proteins. J Virol (2011) 1.13
Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse. PLoS One (2011) 1.13
Glycine 184 in nonstructural protein NS1 determines the virulence of influenza A virus strain PR8 without affecting the host interferon response. J Virol (2010) 1.13
Acute respiratory distress syndrome induced by H9N2 virus in mice. Arch Virol (2009) 1.11
Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence. Virol J (2011) 1.08
Phylogenetic and molecular characterization of H9N2 influenza isolates from chickens in Northern China from 2007-2009. PLoS One (2010) 1.06
Adaptive mutation in influenza A virus non-structural gene is linked to host switching and induces a novel protein by alternative splicing. Emerg Microbes Infect (2012) 1.06
Multifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse. PLoS One (2012) 1.03
Simple genomes, complex interactions: epistasis in RNA virus. Chaos (2010) 1.03
Improved and simplified recombineering approach for influenza virus reverse genetics. J Mol Genet Med (2009) 1.01
Enhanced growth of influenza vaccine seed viruses in vero cells mediated by broadening the optimal pH range for virus membrane fusion. J Virol (2011) 1.00
Serial histopathological examination of the lungs of mice infected with influenza A virus PR8 strain. PLoS One (2011) 0.99
Pandemic (H1N1) 2009 influenza virus induces weaker host immune responses in vitro: a possible mechanism of high transmissibility. Virol J (2011) 0.99
Identification of RNA helicase A as a cellular factor that interacts with influenza A virus NS1 protein and its role in the virus life cycle. J Virol (2011) 0.96
Regulation of nucleocytoplasmic trafficking of viral proteins: an integral role in pathogenesis? Biochim Biophys Acta (2011) 0.96
New regulatory mechanisms for the intracellular localization and trafficking of influenza A virus NS1 protein revealed by comparative analysis of A/PR/8/34 and A/Sydney/5/97. J Gen Virol (2010) 0.96
Highly pathogenic H5N1 influenza A virus strains provoke heterogeneous IFN-α/β responses that distinctively affect viral propagation in human cells. PLoS One (2013) 0.92
Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokines. Funct Integr Genomics (2011) 0.89
The hemagglutinin protein of influenza A/Vietnam/1203/2004 (H5N1) contributes to hyperinduction of proinflammatory cytokines in human epithelial cells. Virology (2010) 0.86
Methionine-101 from one strain of H5N1 NS1 protein determines its IFN-antagonizing ability and subcellular distribution pattern. Sci China Life Sci (2012) 0.78
Deciphering interactions used by the influenza virus NS1 protein to silence the host antiviral sensor protein RIG-I using a bacterial reverse two-hybrid system. Mol Biosyst (2011) 0.77
VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents. Cancer Cell (2003) 5.89
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells. Nature (2011) 4.92
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. J Clin Invest (2010) 3.91
Characterization of H7N9 influenza A viruses isolated from humans. Nature (2013) 3.71
Influenza virus receptor specificity and cell tropism in mouse and human airway epithelial cells. J Virol (2006) 3.60
Evolution of H9N2 influenza viruses from domestic poultry in Mainland China. Virology (2005) 2.72
CD3+ cells at the invasive margin of deeply invading (pT3-T4) colorectal cancer and risk of post-surgical metastasis: a longitudinal study. Lancet Oncol (2009) 2.47
M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro. J Immunol (2009) 2.06
Antigenic and genetic characterization of H9N2 swine influenza viruses in China. J Gen Virol (2007) 1.86
Endoplasmic reticulum dysfunction in neurological disease. Lancet Neurol (2013) 1.83
Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung. J Immunol (2010) 1.76
Evaluation of the stapled transanal rectal resection technique with two staplers in the treatment of obstructive defecation syndrome. J Am Coll Surg (2006) 1.67
Defining the mechanism of polymerization in the serpinopathies. Proc Natl Acad Sci U S A (2010) 1.48
Experimental evolution of human influenza virus H3 hemagglutinin in the mouse lung identifies adaptive regions in HA1 and HA2. J Virol (2008) 1.47
B-type Eph receptors and ephrins induce growth cone collapse through distinct intracellular pathways. J Neurobiol (2003) 1.43
Correction: Influenza Virus Targets Class I MHC-Educated NK Cells for Immunoevasion. PLoS Pathog (2016) 1.39
Cigarette smoke impacts immune inflammatory responses to influenza in mice. Am J Respir Crit Care Med (2006) 1.38
Quantitative proteomic analyses of influenza virus-infected cultured human lung cells. J Virol (2010) 1.27
Simplified recombinational approach for influenza A virus reverse genetics. J Virol Methods (2008) 1.24
PB2 and hemagglutinin mutations are major determinants of host range and virulence in mouse-adapted influenza A virus. J Virol (2010) 1.21
The Subviral RNA Database: a toolbox for viroids, the hepatitis delta virus and satellite RNAs research. BMC Microbiol (2006) 1.17
Negative regulation of lung inflammation and immunopathology by TNF-α during acute influenza infection. Am J Pathol (2011) 1.16
Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins. J Biol Chem (2009) 1.14
Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse. PLoS One (2011) 1.13
alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies. Clin Sci (Lond) (2009) 1.09
Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence. Virol J (2011) 1.08
Gain and loss of multiple functionally related, horizontally transferred genes in the reduced genomes of two microsporidian parasites. Proc Natl Acad Sci U S A (2012) 1.08
Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid. Biochemistry (2003) 1.05
Mapping of clinical and expression quantitative trait loci in a sex-dependent effect of host susceptibility to mouse-adapted influenza H3N2/HK/1/68. J Immunol (2012) 1.03
The human RNA polymerase II interacts with the terminal stem-loop regions of the hepatitis delta virus RNA genome. Virology (2006) 1.03
Multifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse. PLoS One (2012) 1.03
Modulation of human T-cell functions by reactive nitrogen species. Eur J Immunol (2011) 1.03
Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli. Proc Natl Acad Sci U S A (2011) 1.02
Improved and simplified recombineering approach for influenza virus reverse genetics. J Mol Genet Med (2009) 1.01
Treating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infection. PLoS One (2010) 1.01
Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response. J Biol Chem (2009) 1.00
Universal anti-neuraminidase antibody inhibiting all influenza A subtypes. Antiviral Res (2013) 0.99
Mouse-adapted H9N2 influenza A virus PB2 protein M147L and E627K mutations are critical for high virulence. PLoS One (2012) 0.99
The hepatitis delta virus RNA genome interacts with eEF1A1, p54(nrb), hnRNP-L, GAPDH and ASF/SF2. Virology (2009) 0.98
Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency. Hepatology (2013) 0.98
Identification of borinic esters as inhibitors of bacterial cell growth and bacterial methyltransferases, CcrM and MenH. J Med Chem (2005) 0.97
Identification of RNA helicase A as a cellular factor that interacts with influenza A virus NS1 protein and its role in the virus life cycle. J Virol (2011) 0.96
Aurintricarboxylic acid is a potent inhibitor of influenza A and B virus neuraminidases. PLoS One (2009) 0.96
Targeting tumour angiogenesis with small molecule inhibitors of hypoxia inducible factor. Chem Soc Rev (2011) 0.95
Acquisition of an animal gene by microsporidian intracellular parasites. Curr Biol (2011) 0.94
Characterisation of serpin polymers in vitro and in vivo. Methods (2010) 0.94
Immunoglobulin mimicry by Hepatitis C Virus envelope protein E2. Virology (2005) 0.93
Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J Mol Biol (2009) 0.93
A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. J Am Chem Soc (2013) 0.92
Origin of hepatitis delta virus. Future Microbiol (2010) 0.91
Transcription of click-linked DNA in human cells. Angew Chem Int Ed Engl (2014) 0.90
Aqueous stability of oxidized carbon nanotubes and the precipitation by salts. J Hazard Mater (2008) 0.90
Immunogenicity and protective efficacy of an elastase-dependent live attenuated swine influenza virus vaccine administered intranasally in pigs. Vaccine (2010) 0.90
Assessing the biocompatibility of click-linked DNA in Escherichia coli. Nucleic Acids Res (2012) 0.89
Genetic analysis of H3 subtype influenza viruses isolated from domestic ducks in northern China during 2004-2005. Virus Genes (2008) 0.89
The serpinopathies studying serpin polymerization in vivo. Methods Enzymol (2011) 0.89
Interaction of host cellular proteins with components of the hepatitis delta virus. Viruses (2010) 0.89
Expression and secretion of cathelicidin LL-37 in human epithelial cells after infection by Mycobacterium bovis Bacillus Calmette-Guérin. Clin Vaccine Immunol (2008) 0.89
Genetic selection of cyclic peptide Dam methyltransferase inhibitors. Chembiochem (2008) 0.86
Formation of an RNA polymerase II preinitiation complex on an RNA promoter derived from the hepatitis delta virus RNA genome. Nucleic Acids Res (2008) 0.86
Circulating polymers in α1-antitrypsin deficiency. Eur Respir J (2014) 0.85
Mycobacterium bovis BCG Toll-like receptors 2 and 4 cooperation increases the innate epithelial immune response. Arch Med Res (2007) 0.85
10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway. Bioorg Med Chem (2002) 0.85
Binding of the polypyrimidine tract-binding protein-associated splicing factor (PSF) to the hepatitis delta virus RNA. Virology (2006) 0.85
Aggregation of influenza virus ribonucleocapsids at low pH. Virus Res (2002) 0.85
Mycobacterium bovis Bacillus Calmette-Guérin (BCG) stimulates human beta-defensin-2 gene transcription in human epithelial cells. Cell Immunol (2006) 0.84
A monoclonal antibody targeting a highly conserved epitope in influenza B neuraminidase provides protection against drug resistant strains. Biochem Biophys Res Commun (2013) 0.84
The hepatitis delta virus RNA genome interacts with the human RNA polymerases I and III. Virology (2009) 0.83
Latest progress in microsporidian genome research. J Eukaryot Microbiol (2013) 0.83
Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures. Open Biol (2013) 0.83
The universal epitope of influenza A viral neuraminidase fundamentally contributes to enzyme activity and viral replication. J Biol Chem (2013) 0.83
Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway. Bioorg Med Chem (2003) 0.83
Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke. J Transl Med (2011) 0.83
Three new alpha1-antitrypsin deficiency variants help to define a C-terminal region regulating conformational change and polymerization. PLoS One (2012) 0.83
Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase. Bioorg Med Chem (2003) 0.83
The impact of human activities on the flushing properties of a semi-enclosed lagoon: Xiaohai, Hainan, China. Mar Environ Res (2007) 0.82
Prospective randomized clinical trial comparing two different circular staplers for mucosectomy in the treatment of hemorrhoids. World J Surg (2006) 0.82
Role of type I interferon in the bacillus Calmette-Guérin-induced expression of CXCL10 from human monocytes. Mediators Inflamm (2004) 0.82
Synthesis and biological evaluation of N-[4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl]-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway. Bioorg Med Chem (2005) 0.82
Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies. Eur J Hum Genet (2004) 0.82
Evaluation of full-length, cleaved and nitrosylated serum surfactant protein D as biomarkers for COPD. COPD (2011) 0.82
Molecular characterization of the new defective P(brescia) alpha1-antitrypsin allele. Hum Mutat (2009) 0.81
Expression of the serine protease inhibitor neuroserpin in cells of the human myeloid lineage. Thromb Haemost (2007) 0.81
Serologic evidence of prevalent avian H3 subtype influenza virus infection in chickens. Avian Dis (2009) 0.81
Cytoplasmic tail of IL-13Ralpha2 regulates IL-4 signal transduction. Biochem Soc Trans (2009) 0.81
A novel interaction between aging and ER overload in a protein conformational dementia. Genetics (2013) 0.81
Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies. Front Biosci (2004) 0.81
Generation and characterization of a new panel of broadly reactive anti-NS1 mAbs for detection of influenza A virus. J Gen Virol (2012) 0.81
Expression and secretion of CXCL-8 and CXCL-10 from mycobacterium bovis BCG-infected human epithelial cells: role of IL-4. Mediators Inflamm (2006) 0.81
Clinical outcome of frequent exposure to Torque Teno virus (TTV) through blood transfusion in thalassemia patients with or without hepatitis C virus (HCV) infection. J Med Virol (2008) 0.81