PubRank

Robert Schwarzenbacher

Author PubWeight™ 86.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mitochondrial fragmentation in neurodegeneration. Nat Rev Neurosci 2008 4.32
2 OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes. Brain 2007 3.35
3 Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization. Cell 2010 2.96
4 Molecular pathways to neurodegeneration. Nat Med 2004 2.94
5 Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nat Med 2011 2.87
6 Structure of the apoptotic protease-activating factor 1 bound to ADP. Nature 2005 2.63
7 Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol 2003 2.44
8 Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons. Proc Natl Acad Sci U S A 2008 2.17
9 The Fas-FADD death domain complex structure unravels signalling by receptor clustering. Nature 2008 2.11
10 The Nod-like receptor (NLR) family: a tale of similarities and differences. PLoS One 2008 1.99
11 The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat Struct Mol Biol 2003 1.91
12 Identification of small molecule inhibitors of anthrax lethal factor. Nat Struct Mol Biol 2003 1.86
13 Spatiotemporal control of spindle midzone formation by PRC1 in human cells. Proc Natl Acad Sci U S A 2006 1.73
14 Antigen aggregation decides the fate of the allergic immune response. J Immunol 2009 1.64
15 A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses. J Biol Chem 2010 1.55
16 Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold. Proteins 2006 1.51
17 Characterization of the human GARP (Golgi associated retrograde protein) complex. Exp Cell Res 2005 1.30
18 S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease. J Alzheimers Dis 2010 1.26
19 Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 A resolution. Proteins 2004 1.17
20 Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone. Proc Natl Acad Sci U S A 2004 1.13
21 Three-dimensional structure of the NLRP7 pyrin domain: insight into pyrin-pyrin-mediated effector domain signaling in innate immunity. J Biol Chem 2010 1.11
22 Crystal structure of a tandem cystathionine-beta-synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 A resolution. Proteins 2004 1.09
23 The structure of the neurotoxin-associated protein HA33/A from Clostridium botulinum suggests a reoccurring beta-trefoil fold in the progenitor toxin complex. J Mol Biol 2005 1.08
24 Evaluation of Nod-like receptor (NLR) effector domain interactions. PLoS One 2009 1.08
25 Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution. Proteins 2006 1.03
26 Evolution of Crohn's disease-associated Nod2 mutations. Immunogenetics 2008 1.01
27 The NLRP12 pyrin domain: structure, dynamics, and functional insights. J Mol Biol 2011 1.00
28 Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 A resolution reveals a new fold. Proteins 2005 0.99
29 The structure of a biosynthetic intermediate of pyrroloquinoline quinone (PQQ) and elucidation of the final step of PQQ biosynthesis. J Am Chem Soc 2004 0.98
30 Activation and specificity of human caspase-10. Biochemistry 2010 0.98
31 Mutational analysis of human NOD1 and NOD2 NACHT domains reveals different modes of activation. Innate Immun 2011 0.97
32 Response to Detection and analysis of unusual features in the structural model and structure-factor data of a birch pollen allergen. Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 0.96
33 Crystal structure of a novel manganese-containing cupin (TM1459) from Thermotoga maritima at 1.65 A resolution. Proteins 2004 0.92
34 Impact of valency of a glycoprotein B-specific monoclonal antibody on neutralization of herpes simplex virus. J Virol 2010 0.91
35 Crystal structure of an alanine-glyoxylate aminotransferase from Anabaena sp. at 1.70 A resolution reveals a noncovalently linked PLP cofactor. Proteins 2005 0.91
36 The pyrroloquinoline quinone biosynthesis pathway revisited: a structural approach. BMC Biochem 2008 0.91
37 Crystal structure of a ribose-5-phosphate isomerase RpiB (TM1080) from Thermotoga maritima at 1.90 A resolution. Proteins 2004 0.89
38 Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 A resolution. Proteins 2006 0.89
39 Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution. Proteins 2004 0.89
40 Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p. Proteins 2006 0.87
41 Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 1.75 A resolution. Proteins 2004 0.87
42 Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution. Proteins 2004 0.87
43 Crystal structure of a conserved hypothetical protein (gi: 13879369) from Mouse at 1.90 A resolution reveals a new fold. Proteins 2005 0.86
44 Crystal structure of an indigoidine synthase A (IndA)-like protein (TM1464) from Thermotoga maritima at 1.90 A resolution reveals a new fold. Proteins 2005 0.85
45 Crystal structure of Hsp33 chaperone (TM1394) from Thermotoga maritima at 2.20 A resolution. Proteins 2005 0.85
46 Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution. Proteins 2004 0.85
47 Low density lipoproteins as circulating fast temperature sensors. PLoS One 2008 0.85
48 Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution. Proteins 2005 0.84
49 Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 A resolution reveals a new fold. Proteins 2006 0.84
50 Pyrroloquinoline quinone biogenesis: characterization of PqqC and its H84N and H84A active site variants. Biochemistry 2007 0.84
51 Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution. Proteins 2004 0.84
52 Characterization of a protein-generated O₂ binding pocket in PqqC, a cofactorless oxidase catalyzing the final step in PQQ production. Biochemistry 2011 0.83
53 Structural studies of mutant forms of the PQQ-forming enzyme PqqC in the presence of product and substrate. Proteins 2010 0.83
54 Crystal structure of an Apo mRNA decapping enzyme (DcpS) from Mouse at 1.83 A resolution. Proteins 2005 0.83
55 Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 A resolution reveals a new fold with a novel active site. Proteins 2006 0.82
56 Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution. Proteins 2006 0.82
57 Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 A resolution. Proteins 2004 0.82
58 The alpha and beta subchain of Amb a 1, the major ragweed-pollen allergen show divergent reactivity at the IgE and T-cell level. Mol Immunol 2009 0.82
59 Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution. Proteins 2006 0.82
60 Generation of a highly stable, internalizing anti-CD22 single-chain Fv fragment for targeting non-Hodgkin's lymphoma. Int J Cancer 2003 0.81
61 Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold. Proteins 2005 0.80
62 Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 A resolution. Proteins 2006 0.80
63 Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 angstroms resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate. Proteins 2007 0.79
64 Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution. Proteins 2006 0.79
65 Backbone and sidechain (1)H, (15)N and (13)C assignments of the NLRP7 pyrin domain. Biomol NMR Assign 2009 0.79
66 Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function. Proteins 2007 0.78
67 Probing the role of asparagine mutation in thermostability of Bacillus KR-8104 α-amylase. Int J Biol Macromol 2011 0.78
68 Structural insights into inhibition of Bacillus anthracis sporulation by a novel class of non-heme globin sensor domains. J Biol Chem 2011 0.78
69 Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold. Proteins 2005 0.77
70 Crystal structure of a putative NADPH-dependent oxidoreductase (GI: 18204011) from mouse at 2.10 A resolution. Proteins 2004 0.77
71 Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution. Proteins 2004 0.77
72 Two novel missense mutations in iron transport protein transferrin causing hypochromic microcytic anaemia and haemosiderosis: molecular characterization and structural implications. Br J Haematol 2013 0.75
73 Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution. Proteins 2008 0.75
74 Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 A resolution. Proteins 2004 0.75
75 Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00-A resolution reveals a new fold. Proteins 2004 0.75
76 Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 A resolution reveals a new fold. Proteins 2005 0.75