PubRank

Rainer Heuchel

Author PubWeight™ 25.72‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy. Cell Stem Cell 2011 2.78
2 The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains. Genes Dev 2003 2.19
3 Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3. Mol Biol Cell 2003 2.03
4 Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate. Cancer Res 2004 1.72
5 Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice. Nephrol Dial Transplant 2008 1.56
6 Transient activation of NF-kappaB through a TAK1/IKK kinase pathway by TGF-beta1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor formation. Oncogene 2003 1.52
7 Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes. Hepatology 2007 1.19
8 Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation. Blood 2006 1.05
9 CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice. EMBO J 2010 0.96
10 Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene. PLoS One 2011 0.94
11 Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro. J Pathol 2013 0.91
12 Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice. J Cell Mol Med 2008 0.91
13 A gain of function mutation in the activation loop of platelet-derived growth factor beta-receptor deregulates its kinase activity. J Biol Chem 2004 0.91
14 Smad7 regulates the adult neural stem/progenitor cell pool in a transforming growth factor beta- and bone morphogenetic protein-independent manner. Mol Cell Biol 2010 0.91
15 The human alpha11 integrin promoter drives fibroblast-restricted expression in vivo and is regulated by TGF-beta1 in a Smad- and Sp1-dependent manner. Matrix Biol 2009 0.87
16 Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β. Pulm Circ 2011 0.87
17 Tandem Sp1/Sp3 sites together with an Ets-1 site cooperate to mediate alpha11 integrin chain expression in mesenchymal cells. Matrix Biol 2005 0.85
18 Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension. PLoS One 2013 0.81
19 Smad7 regulates terminal maturation of chondrocytes in the growth plate. Dev Biol 2013 0.81
20 An activating mutation in the PDGF receptor-beta causes abnormal morphology in the mouse placenta. Int J Dev Biol 2007 0.78
21 Retracted Editorial Expression of Concern: Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats. Nat Commun 2016 0.75
22 Correction: Immunohistochemical Typing of Adenocarcinomas of the Pancreatobiliary System Improves Diagnosis and Prognostic Stratification. PLoS One 2017 0.75
23 Retraction: Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats. Nat Commun 2017 0.75
24 A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer. J Immunother 2017 0.75
25 Endoscopic papillectomy and KRAS expression in the treatment of adenoma in the major duodenal papilla. Scand J Gastroenterol 2015 0.75