S Govindarajan

Author PubWeight™ 145.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lack of protective immunity against reinfection with hepatitis C virus. Science 1992 4.94
2 Molecular cloning and sequencing of a human hepatitis delta (delta) virus RNA. Nature 1987 4.52
3 Genetic and experimental evidence for cross-species infection by swine hepatitis E virus. J Virol 1998 3.73
4 Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization. Proc Natl Acad Sci U S A 1994 3.56
5 Human hepatitis delta antigen is a nuclear phosphoprotein with RNA-binding activity. J Virol 1988 3.11
6 A single antigenomic open reading frame of the hepatitis delta virus encodes the epitope(s) of both hepatitis delta antigen polypeptides p24 delta and p27 delta. J Virol 1988 2.99
7 Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees. Proc Natl Acad Sci U S A 2000 2.70
8 Prevalence of hepatitis B and C viral markers in black and white patients with hepatocellular carcinoma in the United States. J Natl Cancer Inst 1990 2.23
9 Characterization of hepatitis delta antigen: specific binding to hepatitis delta virus RNA. J Virol 1990 2.17
10 Synthesis of a novel hepatitis C virus protein by ribosomal frameshift. EMBO J 2001 2.03
11 Epidemiology of hepatocellular carcinoma. Can J Gastroenterol 2000 1.80
12 Fulminant B viral hepatitis: role of delta agent. Gastroenterology 1984 1.74
13 Prevalence of delta-antibody among chronic hepatitis B virus infected patients in the Los Angeles area: its correlation with liver biopsy diagnosis. Gastroenterology 1983 1.70
14 The adaptive evolution database (TAED). Genome Biol 2001 1.62
15 NK cells cause liver injury and facilitate the induction of T cell-mediated immunity to a viral liver infection. J Immunol 2000 1.60
16 Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element. Proc Natl Acad Sci U S A 2001 1.54
17 Variation in course of hepatitis E in experimentally infected cynomolgus monkeys. J Infect Dis 1993 1.52
18 Nonviral risk factors for hepatocellular carcinoma in a low-risk population, the non-Asians of Los Angeles County, California. J Natl Cancer Inst 1991 1.50
19 Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV. Hepatology 2000 1.49
20 Utility of a discriminant score for diagnosing advanced fibrosis or cirrhosis in patients with chronic hepatitis C virus infection. Am J Gastroenterol 1997 1.39
21 Experimental infection of chimpanzees with hepatitis C virus of genotype 5a: genetic analysis of the virus and generation of a standardized challenge pool. J Infect Dis 1998 1.38
22 Hepatitis C antibodies in patients with alcoholic liver disease commonly have an identifiable risk factor. J Clin Gastroenterol 1992 1.38
23 Successful passive and active immunization of cynomolgus monkeys against hepatitis E. Proc Natl Acad Sci U S A 1994 1.38
24 Primary hepatocellular carcinoma following perinatal transmission of hepatitis B. West J Med 1988 1.38
25 Host range studies of GB virus-B hepatitis agent, the closest relative of hepatitis C virus, in New World monkeys and chimpanzees. J Med Virol 2001 1.37
26 Experimental transmission of hepatitis C virus-associated fulminant hepatitis to a chimpanzee. J Infect Dis 1999 1.35
27 cDNA clone of hepatitis A virus encoding a virulent virus: induction of viral hepatitis by direct nucleic acid transfection of marmosets. J Virol 1992 1.33
28 A cohort study of serum testosterone and hepatocellular carcinoma in Shanghai, China. Int J Cancer 1995 1.26
29 Heterogeneity of hepatitis delta antigen. Virology 1990 1.23
30 Hepatitis C virus-associated fulminant hepatic failure. N Engl J Med 1996 1.23
31 Piperazinediium dioxamate. Acta Crystallogr Sect E Struct Rep Online 2009 1.21
32 Improved detection of hepatitis C virus antibodies in high-risk populations. Hepatology 1992 1.18
33 Liver fibrosis progression is related to CD4 cell depletion in patients coinfected with hepatitis C virus and human immunodeficiency virus. J Infect Dis 2000 1.18
34 Molecular cloning and characterization of an isolate of hepatitis delta virus from Taiwan. Hepatology 1991 1.17
35 Patients co-infected with human immunodeficiency virus and hepatitis C virus demonstrate higher levels of hepatic HCV RNA. J Viral Hepat 1999 1.16
36 Advances in directed protein evolution by recursive genetic recombination: applications to therapeutic proteins. Curr Opin Biotechnol 2001 1.14
37 Functional inferences from reconstructed evolutionary biology involving rectified databases--an evolutionarily grounded approach to functional genomics. Res Microbiol 2000 1.13
38 Evolution of hepatitis delta virus RNA during chronic infection. Virology 1992 1.13
39 A double-blinded, randomized trial of hydrocortisone in acute hepatic failure. The Acute Hepatic Failure Study Group. Dig Dis Sci 1991 1.13
40 Smoking as an independent risk factor for hepatocellular carcinoma: the Singapore Chinese Health Study. Br J Cancer 2011 1.10
41 Short-term prednisone therapy affects aminotransferase activity and hepatitis C virus RNA levels in chronic hepatitis C. Gastroenterology 1994 1.09
42 Fas-mediated apoptosis causes elimination of virus-specific cytotoxic T cells in the virus-infected liver. J Immunol 2001 1.07
43 Hydatid cyst of the cardiac interventricular septum: report of two cases. Br J Radiol 2007 1.06
44 Experimental infection of chimpanzees with hepatitis G virus and genetic analysis of the virus. J Infect Dis 1998 1.06
45 Epidemic non-A, non-B hepatitis in patients from Pakistan. Ann Intern Med 1987 1.03
46 The bile duct adenoma. A lesion distinct from Meyenburg complex. Arch Pathol Lab Med 1984 1.03
47 Immunogenicity and protective efficacy of a vaccine prepared from 53 kDa truncated hepatitis E virus capsid protein expressed in insect cells. Vaccine 2001 1.02
48 Effects of tumor necrosis factor-alpha and interleukin-6 on fluid-phase permeability and ammonia diffusion in CNS-derived endothelial cells. J Investig Med 1996 1.02
49 Recombinant vaccine against hepatitis E: dose response and protection against heterologous challenge. Vaccine 1997 1.01
50 Inactivated hepatitis A vaccine: active and passive immunoprophylaxis in chimpanzees. Vaccine 1992 1.00
51 Failure to infect rhesus monkeys with hepatitis C virus strains of genotypes 1a, 2a or 3a. J Viral Hepat 2001 0.99
52 Transgenic mice support replication of hepatitis delta virus RNA in multiple tissues, particularly in skeletal muscle. J Virol 1995 0.99
53 Correlation of serum delta RNA with clinical course of acute hepatitis delta virus superinfection in Taiwan: a longitudinal study. J Infect Dis 1990 0.99
54 Natural course of delta superinfection in chronic hepatitis B virus-infected patients: histopathologic study with multiple liver biopsies. Hepatology 1986 0.99
55 Presence of antibodies to the hepatitis B surface antigen is associated with an excess risk for hepatocellular carcinoma among non-Asians in Los Angeles County, California. Hepatology 1997 0.99
56 Immunohistochemical localization of the delta antigen associated with hepatitis B virus in liver biopsy sections embedded in Araldite. Histopathology 1984 0.98
57 A hepatitis A virus deletion mutant which lacks the first pyrimidine-rich tract of the 5' nontranslated RNA remains virulent in primates after direct intrahepatic nucleic acid transfection. J Virol 1995 0.97
58 Delta agent superinfection. Rapidly progressive liver disease in a hepatitis B virus carrier. Arch Pathol Lab Med 1985 0.96
59 Hepatic steatosis in chronic hepatitis C: baseline host and viral characteristics and influence on response to therapy with peginterferon alpha-2a plus ribavirin. J Viral Hepat 2008 0.95
60 Prevalence of hepatitis B-associated delta agent among mentally retarded carriers of HBsAg. J Infect Dis 1985 0.95
61 Prevalence of hepatitis delta (delta) virus infection. A seroepidemiologic study. West J Med 1988 0.94
62 Pathologic features of the liver in acquired immune deficiency syndrome (AIDS). Liver 1986 0.94
63 Spontaneous reactivation in chronic hepatitis B: patterns and natural history. J Clin Gastroenterol 1990 0.93
64 Experience with human immunodeficiency virus infection in patients with hepatitis B virus and hepatitis delta virus infections in Los Angeles, 1977-1985. Am J Epidemiol 1988 0.93
65 Blood group antigens in the intrahepatic biliary tree. II. Type 1 chain N-acetyllactosamine-related carbohydrate antigens in the proliferated bile ductules. J Hepatol 1989 0.93
66 Hepatocellular carcinoma in a case of Wilson's disease. Liver 1992 0.93
67 A simian strain of hepatitis A virus, AGM-27, functions as an attenuated vaccine for chimpanzees. J Infect Dis 1996 0.93
68 Utilization of chimeras between human (HM-175) and simian (AGM-27) strains of hepatitis A virus to study the molecular basis of virulence. J Virol 1998 0.92
69 Possible case of HBV-2 infection. Lancet 1988 0.92
70 Amino-guanidinium hydrogen succinate. Acta Crystallogr Sect E Struct Rep Online 2009 0.91
71 Relapse of acute B viral hepatitis--role of delta agent. Gut 1986 0.91
72 Chronic hepatitis C in ethnic minority patients evaluated in Los Angeles County. Am J Gastroenterol 2001 0.91
73 The stability of serum hepatitis C viral RNA in various handling and storage conditions. Arch Pathol Lab Med 1993 0.91
74 Replication of hepatitis delta virus RNA in mice after intramuscular injection of plasmid DNA. J Virol 1995 0.90
75 Histological benefits of virological response to peginterferon alfa-2a monotherapy in patients with hepatitis C and advanced fibrosis or compensated cirrhosis. Aliment Pharmacol Ther 2008 0.90
76 Lack of association between hepatitis C infection and development of AIDS-related lymphoma. J Acquir Immune Defic Syndr Hum Retrovirol 1999 0.89
77 Experimental transmission of the delta virus to a hepatitis B chronic carrier chimpanzee with the development of persistent delta carriage. Am J Pathol 1986 0.88
78 Delta hepatitis in the Los Angeles area: a report of 126 cases. Ann Intern Med 1986 0.87
79 Intrahepatic lymphocyte phenotypes in hepatitis C virus infection: a comparison between cirrhotic and non-cirrhotic livers. Minerva Gastroenterol Dietol 2007 0.87
80 Effects of iron loading on pathogenicity in hepatitis C virus-infected chimpanzees. Hepatology 1999 0.87
81 alpha-1-Antitrypsin phenotypes in hepatocellular carcinoma. Hepatology 1982 0.86
82 Acute hepatic injury after the withdrawal of immunosuppressive chemotherapy in patients with hepatitis B. Cancer 1990 0.86
83 Fas- and tumor necrosis factor receptor 1-dependent but not perforin-dependent pathways cause injury in livers infected with an adenovirus construct in mice. Hepatology 2000 0.85
84 Nonpercutaneous spread of delta infection. J Infect Dis 1985 0.85
85 Spontaneous reactivation of hepatitis B in Chinese patients with HBsAg-positive chronic active hepatitis. Hepatology 1987 0.85
86 Hepatic inflammation, hepatitis B replication, and cellular immune function in homosexual males with chronic hepatitis B and antibody to human immunodeficiency virus. Am J Gastroenterol 1988 0.84
87 Pathologic and ultrastructural changes of acute and chronic delta hepatitis in an experimentally infected chimpanzee. Am J Pathol 1986 0.83
88 Progress toward the development of a genetically engineered attenuated hepatitis A virus vaccine. J Virol 1996 0.83
89 Extracellular nicotinamide adenine dinucleotide induces t cell apoptosis in vivo and in vitro. J Immunol 2001 0.83
90 Low prevalence of hepatitis C infection in hepatocellular carcinoma (HCC) cases and population controls in Guangxi, a hyperendemic region for HCC in the People's Republic of China. Br J Cancer 1996 0.82
91 Identification of T lymphocytes and subsets in liver biopsy cores of acute viral hepatitis. Liver 1983 0.81
92 Acute delta hepatitis without circulating HBsAg. Gut 1985 0.81
93 Hepatitis B virus DNA in fulminant hepatitis B. Ann Intern Med 1986 0.81
94 Morphologic and immunohistochemical features of fulminant delta hepatitis. Hum Pathol 1985 0.81
95 Evaluation of anti-HBc IgM estimation by radioimmunoassay for anti-HBc on column separated IgM. Ann Clin Lab Sci 1987 0.80
96 HDV infection in the Los Angeles area. Prog Clin Biol Res 1987 0.80
97 Prevalence of hepatitis G virus RNA in the sera of patients with HIV infection. J Acquir Immune Defic Syndr Hum Retrovirol 1998 0.80
98 Clinical significance of hepatitis C viral RNA status and its correlation to antibodies to structural HCV antigens in anti-HCV reactive patients with normal liver tests. J Med Virol 1996 0.80
99 Prospective evaluation of infection with hepatitis G virus in relation to hepatocellular carcinoma in Shanghai, China. J Infect Dis 2000 0.79
100 The Adaptive Evolution Database (TAED). Genome Biol 2001 0.79
101 Sexual transmission of hepatitis D virus infection in Taiwan. Hepatology 1990 0.79
102 Immunohistochemical distribution of renal prostaglandin endoperoxide synthase and prostacyclin synthase: diminished endoperoxide synthase in the hepatorenal syndrome. Hepatology 1987 0.79
103 Chronic infection with hepatitis G virus in relation to hepatocellular carcinoma among non-Asians in Los Angeles County, California. Cancer 1999 0.79
104 Human immunodeficiency virus infection does not alter serum transaminases and hepatitis B virus (HBV) DNA in homosexual patients with chronic HBV infection. Am J Gastroenterol 1991 0.79
105 Prevalence of delta antigen/antibody in B-viral-associated hepatocellular carcinoma. Cancer 1984 0.78
106 Chronic delta infection and liver biopsy changes in chronic active hepatitis B. Ann Intern Med 1984 0.78
107 Permanent HBsAg clearance in chronic hepatitis B viral infection following acute delta superinfection. Dig Dis Sci 1988 0.78
108 Immunoperoxidase study on adenomatoid tumor of the epididymis using anti-mesothelial cell serum. Cancer 1985 0.78
109 Serum hepatitis B viral DNA in acute viral hepatitis B. Ann Intern Med 1989 0.78
110 A lymphocytotoxic factor(s) in plasma of patients with minimal change nephrotic syndrome: partial characterization. Clin Immunol Immunopathol 1983 0.78
111 Status of hepatitis B virus DNA in alcoholic liver disease: a study of a large urban population in the United States. Hepatology 1988 0.78
112 Prevalence of delta agent among Chinese in Taiwan and Los Angeles. J Med Virol 1984 0.77
113 Differential toxicity of the protein phosphatase inhibitors microcystin and calyculin A. J Pharmacol Exp Ther 1995 0.77
114 IgD myeloma. Report of a case with unusual clinical and immunologic features. Am J Clin Pathol 1979 0.77
115 Marked improvement in sensitivity of second-generation tests for acute hepatitis C virus infection. J Infect Dis 1993 0.76
116 A multicentre study of the usefulness of liver biopsy in hepatitis C. J Viral Hepat 2004 0.76
117 Serological response to hepatitis delta virus in hepatitis D. Lancet 1987 0.76
118 Clustering of delta hepatitis in a family from Lebanon. J Infect Dis 1986 0.76
119 Hepatitis D virus (delta agent) superinfection in an endemic area of hepatitis B infection: immunopathologic and serologic findings. Scand J Infect Dis 1987 0.76
120 Pathology-Important Advances in Clinical Medicine: Hepatitis-delta-Agent. West J Med 1984 0.75
121 Serological markers in fulminant hepatitis B. Gut 1984 0.75
122 Assessment of hepatitis C antibody tests in homosexual men with hyperglobulinemia. J Infect Dis 1991 0.75
123 Exploration of sequence space for protein engineering. J Mol Recognit 2001 0.75
124 Delta hepatitis in Denver. West J Med 1988 0.75
125 Incidence of hepatitis D virus infection in Japanese patients with hepatocellular carcinoma--immunohistochemical investigation of the delta antigen. Kurume Med J 1992 0.75
126 Host dependent modulation of hepatitis delta virus replication in chronic delta hepatitis. J Med Virol 1991 0.75
127 The molecular basis of heterogeneity of hepatitis delta virus. J Hepatol 1991 0.75
128 Nodular regenerative hyperplasia of the liver with and without portal hypertension: a comparison. Ann Clin Lab Sci 1986 0.75
129 Infection with the delta agent in Nairobi, Kenya. Trans R Soc Trop Med Hyg 1985 0.75
130 Fulminant delta hepatitis in chronic hepatitis B infection. JAMA 1984 0.75
131 Immunocytochemical identity of hepatocellular hyalin in alcoholic and non-alcoholic liver diseases. Liver 1982 0.75
132 Role of delta agent in fulminant B hepatitis. Biomed Pharmacother 1986 0.75
133 Fatal reactivation of chronic hepatitis B. JAMA 1986 0.75
134 Serum hepatitis B virus DNA in acute hepatitis B. Am J Clin Pathol 1986 0.75
135 Alpha-fetoprotein and its concanavalin A affinity in acute exacerbation of chronic hepatitis B. Am J Gastroenterol 1989 0.75
136 Molecular cloning and sequence analysis of an isolate of hepatitis C virus from Southern California, U.S.A. J Formos Med Assoc 1992 0.75
137 Glycation of lysozyme in a restricted water environment. Proc Natl Sci Counc Repub China B 1991 0.75
138 Acute delta hepatitis: serological diagnosis with particular reference to hepatitis delta virus RNA. Am J Gastroenterol 1991 0.75
139 Detection of hepatitis delta virus in serum and liver tissue by molecular hybridization. Validation of a rapid spot-hybridization technique. Am J Clin Pathol 1989 0.75
140 Spontaneous exacerbation of disease activity in patients with chronic delta hepatitis infection: the role of hepatitis B, C or D? Hepatology 1992 0.75
141 The effect of HIV disease on serum markers of hepatitis delta infection in intravenous drug abusers. J Lab Clin Med 1994 0.75
142 A comparative study of the free amino acids in the haemolymph of three arachnids Phrynicus phipsoni (Palpigradi) Trombidium gigas (Acari) and phalangium opili (Opiliones). Comp Biochem Physiol B 1973 0.75
143 Delta viral hepatitis. Histopathology and course. Pathol Annu 1986 0.75
144 Serum hepatitis B virus-DNA in chronic hepatitis B and delta infection. Arch Pathol Lab Med 1985 0.75
145 The characteristics of alcoholic liver disease in Japan. Clinicopathologic comparison with alcoholic liver disease in the United States. Liver 1987 0.75
146 Anti-HBc in acute viral hepatitis B. Am J Clin Pathol 1986 0.75
147 Role of delta agent in fulminant hepatitis in the Los Angeles area. Prog Clin Biol Res 1983 0.75
148 Hemoglobin Ohio (beta 142 Ala replaced by): a new abnormal hemoglobin with high oxygen affinity and erythrocytosis. Blood 1980 0.75
149 Efficacy of an inactivated hepatitis A vaccine in pre- and postexposure conditions in marmosets. J Infect Dis 1995 0.75
150 Evaluation of enzyme immunoassay for anti-HBc IgM in the diagnosis of acute hepatitis B virus infection. Am J Clin Pathol 1984 0.75
151 Intrahepatic periductal glands in graft-versus-host disease. Acta Pathol Jpn 1988 0.75
152 In vivo transfection by hepatitis A virus synthetic RNA. Arch Virol Suppl 1994 0.75