PubRank

K M Downey

Author PubWeight™ 75.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein. Nature 1987 6.45
2 An auxiliary protein for DNA polymerase-delta from fetal calf thymus. J Biol Chem 1986 4.06
3 Nonnucleoside reverse transcriptase inhibitors that potently and specifically block human immunodeficiency virus type 1 replication. Proc Natl Acad Sci U S A 1991 2.74
4 A new mammalian DNA polymerase with 3' to 5' exonuclease activity: DNA polymerase delta. Biochemistry 1976 2.50
5 Further studies on calf thymus DNA polymerase delta purified to homogeneity by a new procedure. Biochemistry 1984 2.37
6 Studies on the kinetics of ribonucleic acid chain initiation and elongation. Biochemistry 1970 2.18
7 Determination of nucleotide sequences at promoter regions by the use of dinucleotides. Biochemistry 1971 2.16
8 Revised nomenclature for eukaryotic DNA polymerases. Eur J Biochem 1990 1.73
9 Mammalian DNA polymerases alpha and delta: current status in DNA replication. Biochemistry 1988 1.66
10 Polymerase delta variants in RER colorectal tumours. Nat Genet 1995 1.47
11 Primary structure of the catalytic subunit of calf thymus DNA polymerase delta: sequence similarities with other DNA polymerases. Biochemistry 1991 1.44
12 Fidelity of mammalian DNA replication and replicative DNA polymerases. Biochemistry 1991 1.43
13 U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication. Antimicrob Agents Chemother 1993 1.43
14 Proliferating cell nuclear antigen promotes DNA synthesis past template lesions by mammalian DNA polymerase delta. Proc Natl Acad Sci U S A 1997 1.38
15 Structural and functional properties of calf thymus DNA polymerase delta. Prog Nucleic Acid Res Mol Biol 1981 1.31
16 Molecular mechanisms of manganese mutagenesis. Proc Natl Acad Sci U S A 1984 1.22
17 The small subunit is required for functional interaction of DNA polymerase delta with the proliferating cell nuclear antigen. Nucleic Acids Res 1997 1.22
18 Functional characterization of RNA-dependent DNA polymerase and RNase H activities of a recombinant HIV reverse transcriptase. Biochemistry 1991 1.19
19 Autoantibody to the proliferating cell nuclear antigen neutralizes the activity of the auxiliary protein for DNA polymerase delta. Nucleic Acids Res 1987 1.16
20 Enzymologic mechanism of calf thymus DNA polymerase delta. J Biol Chem 1991 1.15
21 Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene. Proc Natl Acad Sci U S A 1991 1.15
22 Mechanism of hemin inhibition of erythroid cytoplasmic DNA polymerase. Biochemistry 1975 1.13
23 Selective inhibition of the 3' to 5' exonuclease activity associated with DNA polymerases: a mechanism of mutagenesis. Biochemistry 1977 1.10
24 Purification of deoxyribonucleic acid polymerase delta from calf thymus: partial characterization of physical properties. Biochemistry 1980 1.09
25 Degradation of deoxyribonucleic acid by a 1,10-phenanthroline-copper complex: the role of hydroxyl radicals. Biochemistry 1980 1.09
26 A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen. Proc Natl Acad Sci U S A 2001 1.08
27 Purification and characterization of the catalytic subunit of human DNA polymerase delta expressed in baculovirus-infected insect cells. J Biol Chem 1996 1.07
28 Proliferating cell nuclear antigen promotes misincorporation catalyzed by calf thymus DNA polymerase delta. J Biol Chem 1996 1.07
29 Studies on the mechanism of ribonucleic acid synthesis. II. Stabilization of the deoxyribonucleic acid-ribonucleic acid polymerase complex by the formation of a single phosphodiester bond. Biochemistry 1970 1.06
30 Reticulocyte RNA-dependent RNA polymerase. Proc Natl Acad Sci U S A 1973 1.04
31 Eukaryotic DNA replication. Crit Rev Biochem Mol Biol 1992 1.04
32 Mechanisms of error discrimination by Escherichia coli DNA polymerase I. Biochemistry 1988 1.03
33 Incorporation and excision of 9-(2-phosphonylmethoxyethyl)guanine (PMEG) by DNA polymerase delta and epsilon in vitro. J Biol Chem 1998 1.03
34 Mechanisms of selective inhibition of 3' to 5' exonuclease activity of Escherichia coli DNA polymerase I by nucleoside 5'-monophosphates. Biochemistry 1978 1.03
35 Purification and characterization of delta helicase from fetal calf thymus. Biochemistry 1992 1.01
36 DNA polymerases alpha and delta are immunologically and structurally distinct. J Biol Chem 1989 1.00
37 Schizosaccharomyces pombe proliferating cell nuclear antigen mutations affect DNA polymerase delta processivity. J Biol Chem 1996 1.00
38 Cloning of the cDNAs for the small subunits of bovine and human DNA polymerase delta and chromosomal location of the human gene (POLD2). Genomics 1995 0.99
39 Bone marrow cytoplasmic deoxyribonucleic acid polymerase. Variation of pH and ionic environment as a possible control mechanism. Biochemistry 1973 0.97
40 Interaction of DNA polymerase delta, proliferating cell nuclear antigen, and synthetic oligonucleotide template-primers. Analysis by polyacrylamide gel electrophoresis-band mobility shift assay. J Biol Chem 1993 0.96
41 Inhibition of the RNase H activity of HIV reverse transcriptase by azidothymidylate. Biochemistry 1991 0.94
42 Effect of base-pair stability of nearest-neighbor nucleotides on the fidelity of deoxyribonucleic acid synthesis. Biochemistry 1984 0.94
43 The mammalian DNA polymerase delta--proliferating cell nuclear antigen--template-primer complex: molecular characterization by direct binding. Biochemistry 1996 0.94
44 Degradation of DNA by 1,-10-phenanthroline. Biochem Biophys Res Commun 1980 0.92
45 Catalytically distinct conformations of the ribonuclease H of HIV-1 reverse transcriptase by substrate cleavage patterns and inhibition by azidothymidylate and N-ethylmaleimide. Biochemistry 1994 0.92
46 9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis. Mol Pharmacol 1999 0.90
47 Architecture of the active DNA polymerase delta.proliferating cell nuclear antigen.template-primer complex. J Biol Chem 1999 0.85
48 Apparent stimulation of calf thymus DNA polymerase alpha by ATP. Nucleic Acids Res 1987 0.81
49 Gastrointestinal side effects after intravenous erythromycin lactobionate. Br J Clin Pharmacol 1986 0.81
50 Translesional synthesis on DNA templates containing an estrogen quinone-derived adduct: N2-(2-hydroxyestron-6-yl)-2'-deoxyguanosine and N6-(2-hydroxyestron-6-yl)-2'-deoxyadenosine. Biochemistry 1998 0.81
51 The benzylthio-pyrimidine U-31,355, a potent inhibitor of HIV-1 reverse transcriptase. Biochem Pharmacol 1996 0.80
52 Mechanism of inhibition of deoxyribonucleic acid synthesis by 1-beta-D-arabinofuranosyladenosine triphosphate and its potentiation by 6-mercaptopurine ribonucleoside 5'-monophosphate. Biochemistry 1980 0.79
53 Selective inhibition of the polymerase activity of DNA polymerase. I. Further evidence for separate active sites for polymerase and 3' to 5' exonuclease activities. Biochemistry 1979 0.79
54 A two-dimensional support for selective binding of polyhistidine-tagged proteins: identification of a proliferating cell nuclear antigen point mutant with altered function in vitro. Anal Biochem 1999 0.78
55 Metabolic regulation of cytoplasmic DNA synthesis. Proc Natl Acad Sci U S A 1974 0.78
56 Chloramphenicol-mediated DNA damage and its possible role in the inhibitory effects of chloramphenicol on DNA synthesis. J Lab Clin Med 1983 0.76
57 Degradation of isolated deoxyribonucleic acid mediated by nitroso-chloramphenicol. Possible role in chloramphenicol-induced aplastic anemia. Biochem Pharmacol 1982 0.76
58 Reticulocyte DNA polymerase. Nature 1974 0.75
59 The effect of 6-mercaptopurine and its derivatives on mammalian RNA-dependent RNA synthesis. Biochem Biophys Res Commun 1974 0.75