Lijun Sun

Author PubWeight™ 129.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005 20.30
2 TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 2007 8.87
3 The specific and essential role of MAVS in antiviral innate immune responses. Immunity 2006 6.74
4 TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. Mol Cell 2004 6.00
5 MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell 2011 5.91
6 Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell 2010 5.83
7 Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proc Natl Acad Sci U S A 2005 5.31
8 Direct activation of protein kinases by unanchored polyubiquitin chains. Nature 2009 4.65
9 NLRX1 is a regulator of mitochondrial antiviral immunity. Nature 2008 4.55
10 Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses. Science 2013 3.61
11 T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20. Nat Immunol 2008 3.45
12 Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects. Science 2013 3.10
13 Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Mol Cell 2013 2.97
14 Antiviral innate immunity pathways. Cell Res 2006 2.80
15 Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3. Mol Cell 2009 2.27
16 Indole- and indolizine-glyoxylamides displaying cytotoxicity against multidrug resistant cancer cell lines. Bioorg Med Chem Lett 2008 1.80
17 Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy. Mol Cancer Ther 2011 1.74
18 MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife 2013 1.63
19 Effects of basic fibroblast growth factor microspheres on angiogenesis in ischemic myocardium and cardiac function: analysis with dobutamine cardiovascular magnetic resonance tagging. Eur J Cardiothorac Surg 2006 1.54
20 Reprogrammed mouse astrocytes retain a "memory" of tissue origin and possess more tendencies for neuronal differentiation than reprogrammed mouse embryonic fibroblasts. Protein Cell 2011 1.52
21 TIFA activates IkappaB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6. Proc Natl Acad Sci U S A 2004 1.28
22 Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity. Clin Cancer Res 2004 1.08
23 Multishot diffusion-weighted imaging features in spinal cord infarction. J Spinal Disord Tech 2005 1.07
24 IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase. J Neurochem 2013 1.07
25 Transcatheter device closure of perimembranous ventricular septal defects: mid-term outcomes. Eur Heart J 2010 1.00
26 A distinct role of RhoB in gastric cancer suppression. Int J Cancer 2011 0.99
27 HIV-1-infected and immune-activated macrophages induce astrocytic differentiation of human cortical neural progenitor cells via the STAT3 pathway. PLoS One 2011 0.89
28 Mitochondrial glutaminase release contributes to glutamate-mediated neurotoxicity during human immunodeficiency virus-1 infection. J Neuroimmune Pharmacol 2012 0.88
29 The nephroprotective effect of tauroursodeoxycholic acid on ischaemia/reperfusion-induced acute kidney injury by inhibiting endoplasmic reticulum stress. Basic Clin Pharmacol Toxicol 2012 0.88
30 PDGF-BB-induced MT1-MMP expression regulates proliferation and invasion of mesenchymal stem cells in 3-dimensional collagen via MEK/ERK1/2 and PI3K/AKT signaling. Cell Signal 2013 0.88
31 Tumor suppressor gene Runx3 sensitizes gastric cancer cells to chemotherapeutic drugs by downregulating Bcl-2, MDR-1 and MRP-1. Int J Cancer 2005 0.88
32 Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274. J Transl Med 2011 0.87
33 Effects of PEMF and glucocorticoids on proliferation and differentiation of osteoblasts. Electromagn Biol Med 2012 0.86
34 The impact of calibration phantom errors on dual-energy digital mammography. Phys Med Biol 2008 0.85
35 Combined T2-weighted and diffusion-weighted MRI for diagnosis of urinary bladder invasion in patients with prostate carcinoma. J Magn Reson Imaging 2009 0.84
36 Application of bFGF and BDNF to improve angiogenesis and cardiac function. J Surg Res 2006 0.83
37 A novel missense mutation in the nuclear factor-κB essential modulator (NEMO) gene resulting in impaired activation of the NF-κB pathway and a unique clinical phenotype presenting as MRSA subdural empyema. J Clin Immunol 2010 0.83
38 Protein phosphatases 2A as well as reactive oxygen species involved in tributyltin-induced apoptosis in mouse livers. Environ Toxicol 2012 0.82
39 ZNRD1 gene suppresses cell proliferation through cell cycle arrest in G1 phase. Cancer Biol Ther 2005 0.82
40 Isolation and identification of an endophytic strain EJS-3 producing novel fibrinolytic enzymes. Curr Microbiol 2007 0.81
41 Quantifying long-term evolution of intra-urban spatial interactions. J R Soc Interface 2015 0.81
42 Regulatory B cells correlate with HIV disease progression. Microbiol Immunol 2014 0.81
43 TNF-α affects human cortical neural progenitor cell differentiation through the autocrine secretion of leukemia inhibitory factor. PLoS One 2012 0.81
44 A new Arg54Gly transthyretin gene mutation associated with vitreous amyloidosis in Chinese. Eye Sci 2011 0.81
45 Arabidopsis poly(ADP-ribose) glycohydrolase 1 is required for drought, osmotic and oxidative stress responses. Plant Sci 2010 0.80
46 Impact of functional constipation on health-related quality of life in preschool children and their families in Xi'an, China. PLoS One 2013 0.80
47 A truncated minimal-E1a gene with potency to support adenoviral replication mediates antitumor activity by down-regulating Neu expression and preserving Rb function. Chem Biol Interact 2009 0.79
48 Immunosuppressive treatment for nephrotic idiopathic membranous nephropathy: a meta-analysis based on Chinese adults. PLoS One 2012 0.79
49 Conjugated indole-imidazole derivatives displaying cytotoxicity against multidrug resistant cancer cell lines. Bioorg Med Chem Lett 2006 0.78
50 Semen cassiae attenuates myocardial ischemia and reperfusion injury in high-fat diet streptozotocin-induced type 2 diabetic rats. Am J Chin Med 2014 0.78
51 Synthesis of fluorescent gold nanoclusters directed by bovine serum albumin and application for nitrite detection. J Fluoresc 2013 0.78
52 Protective effects of sulfated chitooligosaccharides with different degrees of substitution in MIN6 cells. Int J Biol Macromol 2012 0.77
53 Complex formation between heat shock protein 72 and hepatitis B virus X protein in hepatocellular carcinoma tissues. J Proteome Res 2008 0.77
54 Combination of Weight-Bearing Training and Anti-MSTN Polyclonal Antibody Improve Bone Quality in Rats. Int J Sport Nutr Exerc Metab 2016 0.76
55 Syntheses and antitumor activities of N'1,N'3-dialkyl-N'1,N'3-di-(alkylcarbonothioyl) malonohydrazide: the discovery of elesclomol. Bioorg Med Chem Lett 2013 0.76
56 Snail mediates PDGF-BB-induced invasion of rat bone marrow mesenchymal stem cells in 3D collagen and chick chorioallantoic membrane. J Cell Physiol 2013 0.76
57 Health-related quality of life among children with recurrent respiratory tract infections in Xi'an, China. PLoS One 2013 0.75
58 Semisupervised kernel marginal Fisher analysis for face recognition. ScientificWorldJournal 2013 0.75
59 Cloning and characterization of two rice long-chain base kinase genes and their function in disease resistance and cell death. Mol Biol Rep 2012 0.75
60 Detection of airborne trichothecene-producing Fusarium species in chicken houses. Front Biosci (Elite Ed) 2011 0.75
61 Effects of extremely low frequency electromagnetic fields on intracellular calcium transients in cardiomyocytes. Electromagn Biol Med 2014 0.75
62 Treatment of Persistent Gross Hematuria with Tranexamic Acid in Autosomal Dominant Polycystic Kidney Disease. Kidney Blood Press Res 2017 0.75
63 Synthesis, crystallographic characterization and electrochemical property of a copper(II) complex of the anticancer agent elesclomol. J Inorg Biochem 2013 0.75
64 [Isolation and purification of esculetin from the seeds of Euphorbia lathyris L. using high-speed counter-current chromatography]. Se Pu 2010 0.75
65 Inhibition of PP2A and the consequent activation of JNK/c-Jun are involved in tributyltin-induced apoptosis in human amnionic cells. Environ Toxicol 2011 0.75
66 IgA nephropathy in two patients with Sjögren's syndrome: one with concomitant autoimmune hepatitis. Intern Med 2010 0.75
67 Modeling antimicrobial activity of lipopeptides from Bacillus amyloliquefaciens ES-2 against Shewanella putrefaciens in shrimp meat using a response surface method. J Food Prot 2012 0.75
68 HSP72 and gp96 in gastroenterological cancers. Clin Chim Acta 2012 0.75
69 Cutaneous mucormycosis in a patient with lupus nephritis: A case report and review of literature. Medicine (Baltimore) 2017 0.75
70 Olmesartan Prevents Microalbuminuria in db/db Diabetic Mice Through Inhibition of Angiotensin II/p38/SIRT1-Induced Podocyte Apoptosis. Kidney Blood Press Res 2016 0.75
71 [The prevalence and relevant factors of hyperglycemia in AIDS patients receiving antiretroviral therapy in a single center]. Zhonghua Nei Ke Za Zhi 2014 0.75
72 Effect of distinct sources of Ca(2+) on cardiac hypertrophy in cardiomyocytes. Exp Biol Med (Maywood) 2012 0.75
73 [Detection of serum autoantibodies against premelanosome protein 17 increases in the vitiligo patients]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2013 0.75