Published in Can J Ophthalmol on August 01, 2013
Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med (2006) 20.84
Intravitreal aflibercept (VEGF trap-eye) in wet age-related macular degeneration. Ophthalmology (2012) 8.29
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res (2000) 6.42
Metronomic chemotherapy: new rationale for new directions. Nat Rev Clin Oncol (2010) 3.02
Characteristics of patients losing vision after 2 years of monthly dosing in the phase III ranibizumab clinical trials. Ophthalmology (2011) 2.43
Anti-VEGF agents in the treatment of neovascular age-related macular degeneration: applying clinical trial results to the treatment of everyday patients. Am J Ophthalmol (2007) 1.65
Neovascular age-related macular degeneration: potential therapies. Drugs (2008) 1.38
Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration in treatment-naive patients. Acta Ophthalmol (2008) 0.99
Rationale for combination therapy in age-related macular degeneration. Retina (2009) 0.91
Combination therapy for age-related macular degeneration. Retina (2009) 0.88
Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes. Cancer Cell (2003) 3.42
International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathol (2014) 3.21
Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas. Proc Natl Acad Sci U S A (2005) 2.38
Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis. Lancet Oncol (2012) 2.34
Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck. Cancer Res (2005) 2.07
An international strategic plan to preserve and restore vision: four curricula of ophthalmic education. Am J Ophthalmol (2007) 1.99
Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors. Cancer Cell (2009) 1.92
A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue. Sci Transl Med (2012) 1.85
The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. Cancer Cell (2006) 1.63
Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src. J Biol Chem (2003) 1.60
Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor. Proc Natl Acad Sci U S A (2004) 1.52
Viral hijacking of G-protein-coupled-receptor signalling networks. Nat Rev Mol Cell Biol (2004) 1.42
Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia. Ann Thorac Surg (2002) 1.41
Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management. ScientificWorldJournal (2012) 1.40
Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma. Proc Natl Acad Sci U S A (2010) 1.38
Images in clinical medicine. Circumpapillary retinal ridge in the shaken-baby syndrome. N Engl J Med (2004) 1.38
The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy. Cancer Res (2005) 1.35
Hemangiosarcomas, medulloblastomas, and other tumors in Ink4c/p53-null mice. Cancer Res (2003) 1.21
betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development. Mol Cell Neurosci (2007) 1.18
The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia. Blood (2004) 1.17
The role of the immune response in age-related macular degeneration. Int J Inflam (2013) 1.16
In vivo confocal microscopy and diagnosis of limbal stem cell deficiency. Photographing the palisades of vogt and limbal stem cells. Am J Ophthalmol (2013) 1.12
Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4. Proc Natl Acad Sci U S A (2013) 1.12
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor as a therapeutic target for the treatment of Kaposi's sarcoma. Cancer Res (2006) 1.11
Does dysregulated expression of a deregulated viral GPCR trigger Kaposi's sarcomagenesis? FASEB J (2004) 1.10
Acute posterior multifocal placoid pigment epitheliopathy associated with a systemic necrotizing vasculitis. Retina (2003) 1.10
Molecular diagnostics of CNS embryonal tumors. Acta Neuropathol (2010) 1.09
Dual inhibition of PI3Kalpha and mTOR as an alternative treatment for Kaposi's sarcoma. Cancer Res (2008) 1.08
NRF2 plays a protective role in diabetic retinopathy in mice. Diabetologia (2013) 1.06
Abnormal foveal avascular zone in nanophthalmos. Am J Ophthalmol (2007) 1.05
A potential role for beta- and gamma-crystallins in the vascular remodeling of the eye. Dev Dyn (2005) 1.04
Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma. Neoplasia (2010) 1.03
Anecortave acetate as monotherapy for treatment of subfoveal neovascularization in age-related macular degeneration: twelve-month clinical outcomes. Ophthalmology (2003) 1.01
Medulloblastoma subgroups remain stable across primary and metastatic compartments. Acta Neuropathol (2015) 1.00
Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma. PLoS One (2011) 0.98
Persistence of fetal vasculature in a patient with Knobloch syndrome: potential role for endostatin in fetal vascular remodeling of the eye. Ophthalmology (2004) 0.97
A spontaneous mutation affects programmed cell death during development of the rat eye. Exp Eye Res (2005) 0.95
VEGF secreted by hypoxic Müller cells induces MMP-2 expression and activity in endothelial cells to promote retinal neovascularization in proliferative diabetic retinopathy. Diabetes (2013) 0.94
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor: Lessons on dysregulated angiogenesis from a viral oncogene. J Cell Biochem (2010) 0.93
Histopathologic and trypsin digestion studies of the retina in incontinentia pigmenti. Ophthalmology (2007) 0.92
Characterizing the phenotype and genotype of a family with occult macular dystrophy. Arch Ophthalmol (2012) 0.92
Orbital necrobiotic xanthogranuloma associated with systemic IgG4 disease. Ocul Immunol Inflamm (2010) 0.91
A novel mitochondrial tRNA(Leu(UUR)) mutation in a patient with features of MERRF and Kearns-Sayre syndrome. Neuromuscul Disord (2003) 0.91
Long-term, stable differentiation of human embryonic stem cell-derived neural precursors grafted into the adult mammalian neostriatum. Stem Cells (2009) 0.90
Comparison of a digital retinal imaging system and seven-field stereo color fundus photography to detect diabetic retinopathy in the primary care environment. Ophthalmic Surg Lasers Imaging (2005) 0.90
Long-term outcomes in ranibizumab-treated patients with retinal vein occlusion; the role of progression of retinal nonperfusion. Am J Ophthalmol (2013) 0.89
Angiopoietin-like 4: a novel molecular hallmark in oral Kaposi's sarcoma. Oral Oncol (2011) 0.88
Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. Neoplasia (2007) 0.86
A developmental defect in astrocytes inhibits programmed regression of the hyaloid vasculature in the mammalian eye. Eur J Cell Biol (2011) 0.86
Third cranial nerve palsy caused by intracranial extension of a sino-orbital natural killer T-cell lymphoma. J Neuroophthalmol (2008) 0.84
Choroidal neovascularization after central retinal vein occlusion in a 47-year-old man. Arch Ophthalmol (2004) 0.84
VARIABLE EXPRESSION OF RETINOPATHY IN A PEDIGREE OF PATIENTS WITH INCONTINENTIA PIGMENTI. Retina (2015) 0.83
A phase III, multicenter, randomized, placebo-controlled clinical trial of topical aminocaproic acid (Caprogel) in the management of traumatic hyphema. Ophthalmology (2003) 0.83
Medical interventions for traumatic hyphema. Cochrane Database Syst Rev (2013) 0.83
Use of spectral domain-optical coherence tomography to visualize photoreceptor abnormalities in cone-rod dystrophy 6. Retin Cases Brief Rep (2011) 0.83
Medical interventions for traumatic hyphema. Cochrane Database Syst Rev (2011) 0.83
Retrospective case series of juxtafoveal choroidal neovascularization treated with photodynamic therapy with verteporfin. Retina (2004) 0.80
Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines. Bioorg Med Chem (2009) 0.80
Multiple CDK/CYCLIND genes are amplified in medulloblastoma and supratentorial primitive neuroectodermal brain tumor. Cancer Genet (2012) 0.80
Laser targeted photo-occlusion of rat choroidal neovascularization without collateral damage. Photochem Photobiol (2002) 0.80
Management of pediatric and adult patients with medulloblastoma. Curr Treat Options Oncol (2014) 0.80
Histopathologic grading of adult medulloblastomas. Cancer (2007) 0.79
A broad survey of cathepsin K immunoreactivity in human neoplasms. Am J Clin Pathol (2013) 0.79
Activation of the Akt/mTOR pathway in dentigerous cysts, odontogenic keratocysts, and ameloblastomas. Oral Surg Oral Med Oral Pathol Oral Radiol (2013) 0.79
A reappraisal of the clinical spectrum of North Carolina macular dystrophy. Ophthalmology (2009) 0.79
Sarcoidosis presenting as scleral nodule. Ocul Immunol Inflamm (2014) 0.78
Preliminary ocular histopathological observations on heterozygous NEMO-deficient mice. Exp Eye Res (2008) 0.78
Unusual presentation of primary orbital microcystic adnexal carcinoma. J Neuroophthalmol (2011) 0.77
Morphogenetic model for radial streaking in the fundus of the carrier state of X-linked albinism. JAMA Ophthalmol (2013) 0.76
Posterior juxtascleral depot administration of anecortave acetate. Surv Ophthalmol (2007) 0.76
Papillorenal ("renal coloboma") syndrome. Am J Ophthalmol (2002) 0.75
Macular cherry-red spot and corneal haze in sialidosis (mucolipidosis type 1). Arch Ophthalmol (2008) 0.75
Scleral penetration of an unusually aggressive case of a retinal hemangioblastoma. Can J Ophthalmol (2013) 0.75
Papillorenal syndrome in a Brazilian family. Arch Ophthalmol (2002) 0.75
No colobomas in "renal coloboma" syndrome. Ophthalmology (2003) 0.75
Retinitis pigmentosa and punctate cataracts in mevalonic aciduria. Retin Cases Brief Rep (2010) 0.75
Preface. Retina (2005) 0.75
The suboptimal role of optical coherence tomography in diagnosing choroidal metastasis in the macula. Retin Cases Brief Rep (2010) 0.75
Retinal tears occurring at the border of vascular and avascular retina in adult patients with incontinentia pigmenti. Retina (2003) 0.75