Published in PLoS One on July 30, 2013
TALEN-Mediated Gene Disruption on Y Chromosome Reveals Critical Role of EIF2S3Y in Mouse Spermatogenesis. Stem Cells Dev (2015) 0.80
A novel transcriptional factor Nkapl is a germ cell-specific suppressor of Notch signaling and is indispensable for spermatogenesis. PLoS One (2015) 0.78
Nonmyocytic androgen receptor regulates the sexually dimorphic development of the embryonic bulbocavernosus muscle. Endocrinology (2014) 0.78
Screening of whole genome sequences identified high-impact variants for stallion fertility. BMC Genomics (2016) 0.75
The role of Notch signaling in the mammalian ovary. Reproduction (2017) 0.75
Notch signaling controls multiple steps of pancreatic differentiation. Proc Natl Acad Sci U S A (2003) 6.55
Plzf is required in adult male germ cells for stem cell self-renewal. Nat Genet (2004) 5.75
Notch1 is essential for postimplantation development in mice. Genes Dev (1994) 4.06
Functional hierarchy and reversibility within the murine spermatogenic stem cell compartment. Science (2010) 3.33
Controls of germline stem cells, entry into meiosis, and the sperm/oocyte decision in Caenorhabditis elegans. Annu Rev Cell Dev Biol (2007) 3.26
The Notch signalling system: recent insights into the complexity of a conserved pathway. Nat Rev Genet (2012) 2.77
Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway. Dev Biol (2004) 2.59
Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development (2001) 2.37
Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis. Dev Biol (2004) 2.13
The first round of mouse spermatogenesis is a distinctive program that lacks the self-renewing spermatogonia stage. Development (2006) 2.07
The germline stem cell niche unit in mammalian testes. Physiol Rev (2012) 1.86
Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice. Genesis (2008) 1.83
Roles of Pofut1 and O-fucose in mammalian Notch signaling. J Biol Chem (2008) 1.71
The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse. BMC Dev Biol (2009) 1.66
CDH1 is a specific marker for undifferentiated spermatogonia in mouse testes. Biol Reprod (2006) 1.58
SOHLH1 and SOHLH2 coordinate spermatogonial differentiation. Dev Biol (2011) 1.39
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation. Development (2012) 1.39
Drosophila follicle cells are patterned by multiple levels of Notch signaling and antagonism between the Notch and JAK/STAT pathways. Development (2007) 1.33
Functional antagonism between Sall4 and Plzf defines germline progenitors. Cell Stem Cell (2012) 1.24
Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes. J Androl (2001) 1.22
Notch-1, c-kit and GFRalpha-1 are developmentally regulated markers for premeiotic germ cells. Cytogenet Genome Res (2004) 1.06
Expression of Notch pathway components in spermatogonia and Sertoli cells of neonatal mice. J Androl (2001) 1.05
Notch and Egfr signaling act antagonistically to regulate germ-line stem cell niche formation in Drosophila male embryonic gonads. Proc Natl Acad Sci U S A (2010) 1.02
Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence. Dev Biol (2013) 0.94
Sequential activation of Notch family receptors during mouse spermatogenesis. Dev Growth Differ (2003) 0.93
Role of glial cell line-derived neurotrophic factor in germ-line stem cell fate. Ann N Y Acad Sci (2005) 0.92
Complex N-glycans are essential, but core 1 and 2 mucin O-glycans, O-fucose glycans, and NOTCH1 are dispensable, for mammalian spermatogenesis. Biol Reprod (2012) 0.92
Notch signaling in Sertoli cells regulates cyclical gene expression of Hes1 but is dispensable for mouse spermatogenesis. Mol Cell Biol (2011) 0.91
Expression failure of the Notch signaling system is associated with the pathogenesis of maturation arrest in male infertility patients. Fertil Steril (2004) 0.90
Insulin-like 3 signaling is important for testicular descent but dispensable for spermatogenesis and germ cell survival in adult mice. Biol Reprod (2012) 0.90
Cre-conditional expression of constitutively active Notch1 in transgenic mice. Genesis (2007) 0.89
Expression of constitutively active Notch1 in male genital tracts results in ectopic growth and blockage of efferent ducts, epididymal hyperplasia and sterility. Dev Biol (2006) 0.87
Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis. J Pathol (2013) 0.81
Perturbation of Notch/Suppressor of Hairless pathway disturbs migration of primordial germ cells in Xenopus embryo. Dev Growth Differ (2010) 0.79
Rethinking dog domestication by integrating genetics, archeology, and biogeography. Proc Natl Acad Sci U S A (2012) 1.78
Relaxin increases human endothelial progenitor cell NO and migration and vasculogenesis in mice. Blood (2011) 1.56
Relaxin promotes prostate cancer progression. Clin Cancer Res (2007) 1.34
Mutations of the GREAT gene cause cryptorchidism. Hum Mol Genet (2002) 1.27
GREAT/LGR8 is the only receptor for insulin-like 3 peptide. Mol Endocrinol (2003) 1.20
Cryptorchidism in mice with an androgen receptor ablation in gubernaculum testis. Mol Endocrinol (2012) 1.14
Genetic targeting of relaxin and insulin-like factor 3 receptors in mice. Endocrinology (2004) 1.10
Testicular cancer and cryptorchidism. Front Endocrinol (Lausanne) (2013) 1.03
The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): its role in signaling and trafficking to the cell membrane. Endocrinology (2006) 1.02
Suppression of insulin-like3 receptor reveals the role of β-catenin and Notch signaling in gubernaculum development. Mol Endocrinol (2010) 1.01
Insulin-like 3 signalling in testicular descent. Int J Androl (2004) 1.01
T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane. Am J Physiol Endocrinol Metab (2006) 0.99
Mutations in the insulin-like factor 3 receptor are associated with osteoporosis. J Bone Miner Res (2008) 0.96
Developmental expression and gene regulation of insulin-like 3 receptor RXFP2 in mouse male reproductive organs. Biol Reprod (2007) 0.96
Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis. Endocr Relat Cancer (2010) 0.95
INSL3/RXFP2 signaling in testicular descent. Ann N Y Acad Sci (2009) 0.92
The role of relaxin in endometrial cancer. Cancer Biol Ther (2006) 0.91
Insulin-like 3 signaling is important for testicular descent but dispensable for spermatogenesis and germ cell survival in adult mice. Biol Reprod (2012) 0.90
Relaxin acts on stromal cells to promote epithelial and stromal proliferation and inhibit apoptosis in the mouse cervix and vagina. Endocrinology (2008) 0.90
Endocrine effects of relaxin overexpression in mice. Endocrinology (2005) 0.89
Successful targeting of mouse Y chromosome genes using a site-directed insertion vector. Genesis (2002) 0.89
A major locus on mouse chromosome 18 controls XX sex reversal in Odd Sex (Ods) mice. Hum Mol Genet (2003) 0.89
Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1. Nat Commun (2013) 0.88
Identification of small-molecule agonists of human relaxin family receptor 1 (RXFP1) by using a homogenous cell-based cAMP assay. J Biomol Screen (2012) 0.86
Over expression of insulin-like 3 does not prevent cryptorchidism in GNRHR or HOXA10 deficient mice. J Urol (2006) 0.85
Novel mutations involving the INSL3 gene associated with cryptorchidism. J Urol (2007) 0.84
Protein expression profiling of endometriosis: validation of 2-mm tissue microarrays. Fertil Steril (2004) 0.83
The fate of spermatogonial stem cells in the cryptorchid testes of RXFP2 deficient mice. PLoS One (2013) 0.82
Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis. J Pathol (2013) 0.81
Transabdominal testicular descent is disrupted in mice with deletion of insulinlike factor 3 receptor. J Pediatr Surg (2003) 0.81
Cryptorchidism--an estrogen spoil? J Clin Endocrinol Metab (2005) 0.80
A missense mutation in LRR8 of RXFP2 is associated with cryptorchidism. Mamm Genome (2010) 0.80
Expression of LDL-A module of relaxin receptor in prostate cancer cells inhibits tumorigenesis. Int J Oncol (2011) 0.80
Genetic targeting of relaxin and insl3 signaling in mice. Ann N Y Acad Sci (2005) 0.80
INSL3 has tumor-promoting activity in thyroid cancer. Int J Cancer (2010) 0.80
Normal fertility in male mice with deletion of β-catenin gene in germ cells. Genesis (2014) 0.79
Relaxin/RXFP1 signaling in prostate cancer progression. Ann N Y Acad Sci (2009) 0.79
INSL3 plays a role in the balance between bone formation and resorption. Ann N Y Acad Sci (2009) 0.79
Isolation and expression analysis of the canine insulin-like factor 3 gene. Biol Reprod (2003) 0.78
Relaxin signaling in uterine fibroids. Ann N Y Acad Sci (2009) 0.78
New roles for INSL3 in adults. Ann N Y Acad Sci (2009) 0.78
Relative roles of the epithelial and stromal tissue compartment(s) in mediating the actions of relaxin and estrogen on cell proliferation and apoptosis in the mouse lower reproductive tract. Ann N Y Acad Sci (2009) 0.76
Structural Insights into the Activation of Human Relaxin Family Peptide Receptor 1 by Small-Molecule Agonists. Biochemistry (2016) 0.76
Mutation analysis of INSL3 and GREAT/LGR8 genes in familial cryptorchidism. Urology (2004) 0.76
Reduced androgen receptor expression accelerates the onset of ERBB2 induced breast tumors in female mice. PLoS One (2013) 0.75
Normal prostate morphology in relaxin-mutant mice. Reprod Fertil Dev (2009) 0.75
Uterine cysts in female mice deficient for caveolin-1 and insulin-like 3 receptor RXFP2. Endocrinology (2011) 0.75
Mechanisms of INSL3 signaling in male reproductive organs. Ital J Anat Embryol (2013) 0.75