Published in J Control Release on August 28, 2013
Liposomes as nanomedical devices. Int J Nanomedicine (2015) 1.29
Image-guided interventional therapy for cancer with radiotherapeutic nanoparticles. Adv Drug Deliv Rev (2014) 0.84
GEM-loaded magnetic albumin nanospheres modified with cetuximab for simultaneous targeting, magnetic resonance imaging, and double-targeted thermochemotherapy of pancreatic cancer cells. Int J Nanomedicine (2015) 0.80
Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models. J Clin Invest (2015) 0.79
CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery. J Control Release (2015) 0.79
Spatial and Temporal Control of Hyperthermia Using Real Time Ultrasonic Thermal Strain Imaging with Motion Compensation, Phantom Study. PLoS One (2015) 0.79
Convertible MRI contrast: Sensing the delivery and release of anti-glioma nano-drugs. Sci Rep (2015) 0.79
Assessing Therapeutic Potential of Magnetic Mesoporous Nanoassemblies for Chemo-Resistant Tumors. Theranostics (2016) 0.75
Multi-focal HIFU reduces cavitation in mild-hyperthermia. J Ther Ultrasound (2017) 0.75
Intracellular trafficking of a pH-responsive drug metal complex. J Control Release (2016) 0.75
Thermal combination therapies for local drug delivery by magnetic resonance-guided high-intensity focused ultrasound. Proc Natl Acad Sci U S A (2017) 0.75
Strategies for improving the intratumoral distribution of liposomal drugs in cancer therapy. Expert Opin Drug Deliv (2016) 0.75
The study on the preparation and characterization of gene-loaded immunomagnetic albumin nanospheres and their anti-cell proliferative effect combined with magnetic fluid hyperthermia on GLC-82 cells. Drug Des Devel Ther (2015) 0.75
PBCA-based polymeric microbubbles for molecular imaging and drug delivery. J Control Release (2017) 0.75
Dynamic contrast enhanced MRI detects changes in vascular transport rate constants following treatment with thermally-sensitive liposomal doxorubicin. J Control Release (2017) 0.75
The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv Enzyme Regul (2001) 6.59
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliv Rev (2010) 5.26
Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer. EMBO J (1999) 3.79
An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. J Clin Invest (2011) 3.69
Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. Cancer Res (2000) 3.10
A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model. Cancer Res (2000) 2.99
The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo. Adv Drug Deliv Rev (2012) 2.99
Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim Biophys Acta (1993) 2.92
Pulsed-high intensity focused ultrasound and low temperature-sensitive liposomes for enhanced targeted drug delivery and antitumor effect. Clin Cancer Res (2007) 2.17
Anthracycline cardiotoxicity: from bench to bedside. J Clin Oncol (2008) 2.04
Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects. J Natl Cancer Inst (2007) 2.03
Thresholds for thermal damage to normal tissues: an update. Int J Hyperthermia (2011) 1.86
Enhanced in vivo bioluminescence imaging using liposomal luciferin delivery system. J Control Release (2009) 1.60
Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer. Cancer Res (2008) 1.59
Hyperthermia adds to chemotherapy. Eur J Cancer (2008) 1.57
Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors. Cancer Res (2012) 1.38
A comparison of liposomal formulations of doxorubicin with drug administered in free form: changing toxicity profiles. Drug Saf (2001) 1.33
Magnetic resonance imaging of high intensity focused ultrasound mediated drug delivery from temperature-sensitive liposomes: an in vivo proof-of-concept study. J Control Release (2010) 1.32
The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey. Chem Phys Lipids (1990) 1.31
For the clinical application of thermochemotherapy given at mild temperatures. Int J Hyperthermia (1999) 1.27
Lyso-thermosensitive liposomal doxorubicin: a novel approach to enhance efficacy of thermal ablation of liver cancer. Expert Opin Pharmacother (2009) 1.19
Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient. Biochim Biophys Acta (1998) 1.18
Uptake of antineoplastic agents into large unilamellar vesicles in response to a membrane potential. Biochim Biophys Acta (1985) 1.18
Nanoscale Drug Delivery and Hyperthermia: The Materials Design and Preclinical and Clinical Testing of Low Temperature-Sensitive Liposomes Used in Combination with Mild Hyperthermia in the Treatment of Local Cancer. Open Nanomed J (2011) 1.14
Effect of pazopanib on tumor microenvironment and liposome delivery. Mol Cancer Ther (2010) 1.09
Chemodosimetry of in vivo tumor liposomal drug concentration using MRI. Magn Reson Med (2006) 1.08
Comparative effects of thermosensitive doxorubicin-containing liposomes and hyperthermia in human and murine tumours. Int J Hyperthermia (2010) 1.08
Hyperthermia and thermosensitive liposomes for improved delivery of chemotherapeutic drugs to solid tumors. Pharm Res (2010) 1.08
An imaging-driven model for liposomal stability and circulation. Mol Pharm (2010) 1.05
Efficient tumor regression by a single and low dose treatment with a novel and enhanced formulation of thermosensitive liposomal doxorubicin. J Control Release (2011) 1.03
Transmembrane gradient driven phase transitions within vesicles: lessons for drug delivery. Biochim Biophys Acta (1995) 1.00
Copper-doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity. Mol Pharm (2010) 0.97
Loading of amphipathic weak acids into liposomes in response to transmembrane calcium acetate gradients. Biochim Biophys Acta (1995) 0.97
Pharmacokinetics & tissue distribution of temperature-sensitive liposomal doxorubicin in tumor-bearing mice triggered with mild hyperthermia. Biomaterials (2012) 0.97
The materials engineering of temperature-sensitive liposomes. Methods Enzymol (2004) 0.88
Experimental studies of the effects of local hyperthermia on blood flow, oxygen pressure and pH in tumors. Jpn J Surg (1988) 0.87
A thermosensitive liposome prepared with a Cu²⁺ gradient demonstrates improved pharmacokinetics, drug delivery and antitumor efficacy. J Control Release (2012) 0.82
Combination sonodynamic therapy with immunoadjuvant may be a promising new modality for cancer treatment. Med Hypotheses (2009) 0.81
Sequence dependence of the hyperthermic potentiation of carboplatin-induced cytotoxicity and intracellular platinum accumulation in HeLa cells. Br J Cancer (1993) 0.80
Spectroscopic studies of copper(II) and iron(II) complexes of adriamycin. Spectrochim Acta A Mol Biomol Spectrosc (2000) 0.80
Nonenzymatic oxygen activation and stimulation of lipid peroxidation by doxorubicin-copper. Toxicol Appl Pharmacol (1986) 0.79
The magnitude of radiation force on ultrasound contrast agents. J Acoust Soc Am (2002) 2.38
Ultrasound contrast microbubbles in imaging and therapy: physical principles and engineering. Phys Med Biol (2009) 2.27
Radiation-force assisted targeting facilitates ultrasonic molecular imaging. Mol Imaging (2004) 2.19
Direct observations of ultrasound microbubble contrast agent interaction with the microvessel wall. J Acoust Soc Am (2007) 2.11
Acoustic response of compliable microvessels containing ultrasound contrast agents. Phys Med Biol (2006) 1.91
Targeted imaging using ultrasound. J Magn Reson Imaging (2002) 1.88
Enhancement of vascular permeability with low-frequency contrast-enhanced ultrasound in the chorioallantoic membrane model. Radiology (2007) 1.86
A method for radiation-force localized drug delivery using gas-filled lipospheres. IEEE Trans Ultrason Ferroelectr Freq Control (2004) 1.79
Motion corrected cadence CPS ultrasound for quantifying response to vasoactive drugs in a rat kidney model. Urology (2009) 1.78
Influence of lipid shell physicochemical properties on ultrasound-induced microbubble destruction. IEEE Trans Ultrason Ferroelectr Freq Control (2005) 1.77
Therapeutic effects of paclitaxel-containing ultrasound contrast agents. Ultrasound Med Biol (2006) 1.75
Acoustically-active microbubbles conjugated to liposomes: characterization of a proposed drug delivery vehicle. J Control Release (2006) 1.70
Ultrasound radiation force enables targeted deposition of model drug carriers loaded on microbubbles. J Control Release (2005) 1.68
Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proc Natl Acad Sci U S A (2013) 1.66
Ultrasound molecular imaging of tumor angiogenesis with an integrin targeted microbubble contrast agent. Invest Radiol (2011) 1.64
Long-circulating liposomes radiolabeled with [18F]fluorodipalmitin ([18F]FDP). Nucl Med Biol (2007) 1.60
Enhanced in vivo bioluminescence imaging using liposomal luciferin delivery system. J Control Release (2009) 1.60
Lateral phase separation in lipid-coated microbubbles. Langmuir (2006) 1.52
Ultrasonic analysis of peptide- and antibody-targeted microbubble contrast agents for molecular imaging of alphavbeta3-expressing cells. Mol Imaging (2004) 1.49
Targeted imaging using ultrasound contrast agents. Progess and opportunities for clinical and research applications. IEEE Eng Med Biol Mag (2004) 1.46
Accumulation, internalization and therapeutic efficacy of neuropilin-1-targeted liposomes. J Control Release (2014) 1.44
Application of ultrasound to selectively localize nanodroplets for targeted imaging and therapy. Mol Imaging (2006) 1.43
A novel method to label preformed liposomes with 64Cu for positron emission tomography (PET) imaging. Bioconjug Chem (2008) 1.39
Contrast-enhanced US of microcirculation of superficially implanted tumors in rats. Radiology (2003) 1.38
Imaging of angiogenesis using Cadence contrast pulse sequencing and targeted contrast agents. Contrast Media Mol Imaging (2008) 1.34
Dynamics of therapeutic ultrasound contrast agents. Ultrasound Med Biol (2002) 1.32
The natural frequency of nonlinear oscillation of ultrasound contrast agents in microvessels. Ultrasound Med Biol (2007) 1.30
Effect of coupled oscillations on microbubble behavior. J Acoust Soc Am (2003) 1.29
Ultrasound radiation force modulates ligand availability on targeted contrast agents. Mol Imaging (2006) 1.23
A stimulus-responsive contrast agent for ultrasound molecular imaging. Biomaterials (2007) 1.22
Vascular endothelial growth factor-C stimulates the lymphatic pump by a VEGF receptor-3-dependent mechanism. Am J Physiol Heart Circ Physiol (2007) 1.19
Contrast-enhanced computed tomography and ultrasound for the evaluation of tumor blood flow. Invest Radiol (2005) 1.17
A new imaging strategy using wideband transient response of ultrasound contrast agents. IEEE Trans Ultrason Ferroelectr Freq Control (2005) 1.17
A radio-frequency coupling network for heating of citrate-coated gold nanoparticles for cancer therapy: design and analysis. IEEE Trans Biomed Eng (2011) 1.17
Dynamic microPET imaging of ultrasound contrast agents and lipid delivery. J Control Release (2008) 1.16
DNA and polylysine adsorption and multilayer construction onto cationic lipid-coated microbubbles. Langmuir (2007) 1.16
Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies. Cancer Res (2011) 1.13
Ultrasound increases nanoparticle delivery by reducing intratumoral pressure and increasing transport in epithelial and epithelial-mesenchymal transition tumors. Cancer Res (2012) 1.12
Spatial and temporal-controlled tissue heating on a modified clinical ultrasound scanner for generating mild hyperthermia in tumors. IEEE Trans Biomed Eng (2010) 1.12
Asymmetric oscillation of adherent targeted ultrasound contrast agents. Appl Phys Lett (2005) 1.12
Acoustic response from adherent targeted contrast agents. J Acoust Soc Am (2006) 1.11
Efficient array design for sonotherapy. Phys Med Biol (2008) 1.07
Quantitative evaluation of perfusion and permeability of peripheral tumors using contrast-enhanced computed tomography. Invest Radiol (2004) 1.07
Dynamics and fragmentation of thick-shelled microbubbles. IEEE Trans Ultrason Ferroelectr Freq Control (2002) 1.07
Ultrasound-driven microbubble oscillation and translation within small phantom vessels. Ultrasound Med Biol (2007) 1.05
Angiogenic response to bioactive glass promotes bone healing in an irradiated calvarial defect. Tissue Eng Part A (2009) 1.05
An imaging-driven model for liposomal stability and circulation. Mol Pharm (2010) 1.05
A role for long chain myosin light chain kinase (MLCK-210) in microvascular hyperpermeability during severe burns. Shock (2007) 1.05
Dynamic imaging of arginine-rich heart-targeted vehicles in a mouse model. Biomaterials (2008) 1.03
High-frequency dynamics of ultrasound contrast agents. IEEE Trans Ultrason Ferroelectr Freq Control (2005) 1.02
An open environment CT-US fusion for tissue segmentation during interventional guidance. PLoS One (2011) 1.02
Ultrasound assessment of angiogenesis in a matrigel model in rats. Ultrasound Med Biol (2006) 1.02
Noninvasive thermometry assisted by a dual-function ultrasound transducer for mild hyperthermia. IEEE Trans Ultrason Ferroelectr Freq Control (2010) 1.01
The effect of size on the acoustic response of polymer-shelled contrast agents. Ultrasound Med Biol (2005) 0.99
Contrast-assisted destruction-replenishment ultrasound for the assessment of tumor microvasculature in a rat model. Technol Cancer Res Treat (2002) 0.99
Copper-doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity. Mol Pharm (2010) 0.97
A sensitive TLRH targeted imaging technique for ultrasonic molecular imaging. IEEE Trans Ultrason Ferroelectr Freq Control (2010) 0.96
Long-circulating 15 nm micelles based on amphiphilic 3-helix peptide-PEG conjugates. ACS Nano (2012) 0.96
Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice. Proc Natl Acad Sci U S A (2011) 0.95
Longitudinal investigation of permeability and distribution of macromolecules in mouse malignant transformation using PET. Clin Cancer Res (2010) 0.94
Insonation of targeted microbubbles produces regions of reduced blood flow within tumor vasculature. Invest Radiol (2012) 0.94
Liposomal Cu-64 labeling method using bifunctional chelators: poly(ethylene glycol) spacer and chelator effects. Bioconjug Chem (2010) 0.93
Magnetic resonance thermometry at 7T for real-time monitoring and correction of ultrasound induced mild hyperthermia. PLoS One (2012) 0.93
A new high resolution color flow system using an eigendecomposition-based adaptive filter for clutter rejection. IEEE Trans Ultrason Ferroelectr Freq Control (2002) 0.92
Evaluation of doxorubicin-loaded 3-helix micelles as nanocarriers. Biomacromolecules (2013) 0.92
Quantitative contrast enhanced ultrasound and CT assessment of tumor response to antiangiogenic therapy in rats. Ultrasound Med Biol (2007) 0.91
Transmitted ultrasound pressure variation in micro blood vessel phantoms. Ultrasound Med Biol (2008) 0.91
A comparison of image contrast with (64)Cu-labeled long circulating liposomes and (18)F-FDG in a murine model of mammary carcinoma. Am J Nucl Med Mol Imaging (2013) 0.90
A new high resolution color flow system using an eigendecomposition-based adaptive filter for clutter rejection. IEEE Trans Ultrason Ferroelectr Freq Control (2002) 0.90
High-resolution functional vascular assessment with ultrasound. IEEE Trans Med Imaging (2004) 0.90
Optical and acoustical interrogation of submicron contrast agents. IEEE Trans Ultrason Ferroelectr Freq Control (2002) 0.89
Microbubble tunneling in gel phantoms. J Acoust Soc Am (2009) 0.89
A role for endothelial-derived matrix metalloproteinase-2 in breast cancer cell transmigration across the endothelial-basement membrane barrier. Clin Exp Metastasis (2007) 0.89
Cholesterol transport from liposomal delivery vehicles. Biomaterials (2007) 0.89
Mechanism of gallic acid biosynthesis in bacteria (Escherichia coli) and walnut (Juglans regia). Plant Mol Biol (2011) 0.86
Novel ultrasound and DCE-MRI analyses after antiangiogenic treatment with a selective VEGF receptor inhibitor. Ultrasound Med Biol (2011) 0.85