Published in Cell Death Differ on September 06, 2013
Gα12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinoma. Oncogene (2014) 1.13
Salinomycin decreases doxorubicin resistance in hepatocellular carcinoma cells by inhibiting the β-catenin/TCF complex association via FOXO3a activation. Oncotarget (2015) 1.01
Wnt inhibitory factor 1 suppresses cancer stemness and induces cellular senescence. Cell Death Dis (2014) 0.86
ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres. Brain Pathol (2015) 0.83
Anoikis and EMT: Lethal "Liaisons" during Cancer Progression. Crit Rev Oncog (2016) 0.81
Risk factors for etiology and prognosis of mantle cell lymphoma. Expert Rev Hematol (2014) 0.79
Tumour-promoting role of EMT-inducing transcription factor ZEB1 in mantle cell lymphoma. Cell Death Differ (2014) 0.78
Identification of microRNAs implicated in the late differentiation stages of normal B cells suggests a central role for miRNA targets ZEB1 and TP53. Oncotarget (2017) 0.77
RNA-seq identifies determinants of oxaliplatin sensitivity in colorectal cancer cell lines. Int J Clin Exp Pathol (2014) 0.76
KSHV-Mediated Regulation of Par3 and SNAIL Contributes to B-Cell Proliferation. PLoS Pathog (2016) 0.75
Ionophore Antibiotics as Cancer Stem Cell-Selective Drugs: Open Questions. Oncologist (2016) 0.75
Long non-coding RNA linc00673 regulated non-small cell lung cancer proliferation, migration, invasion and epithelial mesenchymal transition by sponging miR-150-5p. Mol Cancer (2017) 0.75
EMT and MET-related processes in non-epithelial tumors: importance for disease progression, prognosis and therapeutic opportunities. Mol Oncol (2017) 0.75
miR-3656 expression enhances the chemosensitivity of pancreatic cancer to gemcitabine through modulation of the RHOF/EMT axis. Cell Death Dis (2017) 0.75
Wnt/β-catenin signaling and disease. Cell (2012) 16.05
Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell (2009) 12.96
Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res (2010) 12.96
A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature (2003) 12.81
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med (2004) 11.29
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol (2009) 8.63
WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer (2013) 6.64
Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer (2013) 6.13
The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma. Cancer Cell (2003) 6.11
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science (2010) 4.37
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res (2008) 4.04
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology (2006) 3.68
Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover. Nat Cell Biol (2000) 3.14
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J (2003) 2.67
ZEB represses transcription through interaction with the corepressor CtBP. Proc Natl Acad Sci U S A (1999) 2.64
Activation of the Wnt signaling pathway in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (2004) 2.60
Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development (2008) 2.55
How I treat mantle cell lymphoma. Blood (2009) 2.50
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proc Natl Acad Sci U S A (2004) 2.46
β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness. Proc Natl Acad Sci U S A (2011) 2.45
The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. Cold Spring Harb Symp Quant Biol (1999) 2.40
ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1. Oncogene (2010) 2.25
Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway. EMBO J (2003) 2.20
EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness. Cell Mol Life Sci (2012) 2.12
Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells. Proc Natl Acad Sci U S A (2011) 2.12
Molecular pathogenesis of mantle cell lymphoma. J Clin Invest (2012) 1.92
Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma. Blood (2008) 1.88
Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors. Proc Natl Acad Sci U S A (2012) 1.80
Differential expression and function of members of the zfh-1 family of zinc finger/homeodomain repressors. Proc Natl Acad Sci U S A (2000) 1.73
Stem-like tumor cells confer drug resistant properties to mantle cell lymphoma. Leuk Lymphoma (2011) 1.71
Expression of human equilibrative nucleoside transporter 1 (hENT1) and its correlation with gemcitabine uptake and cytotoxicity in mantle cell lymphoma. Haematologica (2006) 1.55
Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma. Blood (2010) 1.53
ESMO Consensus conferences: guidelines on malignant lymphoma. part 2: marginal zone lymphoma, mantle cell lymphoma, peripheral T-cell lymphoma. Ann Oncol (2013) 1.51
Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray. Blood (2001) 1.50
Evaluation of the MDR1, ABCG2, Topoisomerases IIalpha and GSTpi gene expression in patients affected by aggressive mantle cell lymphoma treated by the R-Hyper-CVAD regimen. Leuk Lymphoma (2007) 1.44
Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma. Blood (2008) 1.43
ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer. Int J Cancer (2012) 1.43
Activation of Wnt/beta-catenin pathway mediates growth and survival in B-cell progenitor acute lymphoblastic leukaemia. Br J Haematol (2007) 1.40
Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFbeta signalling pathways. Br J Haematol (2005) 1.37
The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor. Blood Cells Mol Dis (2010) 1.34
Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia. Leukemia (2009) 1.29
The molecular signature of mantle cell lymphoma reveals multiple signals favoring cell survival. Cancer Res (2003) 1.27
Expanding roles of ZEB factors in tumorigenesis and tumor progression. Am J Cancer Res (2011) 1.26
A chromosomal translocation in cyclin D1-negative/cyclin D2-positive mantle cell lymphoma fuses the CCND2 gene to the IGK locus. Blood (2006) 1.25
Pharmacogenetics/genomics of membrane transporters in cancer chemotherapy. Cancer Metastasis Rev (2007) 1.17
Wnt signaling in normal and malignant hematopoiesis. Cold Spring Harb Perspect Biol (2013) 1.14
Nuclear survivin expression in mantle cell lymphoma is associated with cell proliferation and survival. Am J Pathol (2004) 1.13
Selective inhibition of IkappaB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level. J Immunol (2007) 1.09
Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma. Clin Cancer Res (2012) 1.08
Ki-67 expression level, histological subtype, and the International Prognostic Index as outcome predictors in mantle cell lymphoma. Eur J Haematol (2002) 1.08
CDK4 and MDM2 gene alterations mainly occur in highly proliferative and aggressive mantle cell lymphomas with wild-type INK4a/ARF locus. Cancer Res (2005) 1.07
Five-gene model to predict survival in mantle-cell lymphoma using frozen or formalin-fixed, paraffin-embedded tissue. J Clin Oncol (2008) 1.05
The zinc finger transcription factor ZFHX1A is linked to cell proliferation by Rb-E2F1. Biochem J (2007) 1.03
ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1. Clin Cancer Res (2013) 0.96
Inactivation of RB1 in mantle-cell lymphoma detected by nonsense-mediated mRNA decay pathway inhibition and microarray analysis. Blood (2007) 0.96
Functionally associated targets in mantle cell lymphoma as defined by DNA microarrays and RNA interference. Blood (2007) 0.90
Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis. BMC Cancer (2008) 0.87
The Wnt signaling pathway and mitotic regulators in the initiation and evolution of mantle cell lymphoma: Gene expression analysis. Int J Oncol (2013) 0.84
Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of beta-catenin/TCF pathway. Leukemia (2007) 0.83