Efficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis.

PubWeight™: 1.82‹?› | Rank: Top 3%

🔗 View Article (PMC 3826344)

Published in CMAJ on September 16, 2013

Authors

Andrea C Tricco, Charlene Soobiah, Shirra Berliner, Joanne M Ho, Carmen H Ng, Huda M Ashoor, Maggie H Chen, Brenda Hemmelgarn, Sharon E Straus

Articles citing this

Pharmacological cognitive enhancement-how neuroscientific research could advance ethical debate. Front Syst Neurosci (2014) 1.00

Mild cognitive impairment: diagnosis, longitudinal course, and emerging treatments. Curr Psychiatry Rep (2014) 0.89

Early intervention in Alzheimer's disease: a health economic study of the effects of diagnostic timing. BMC Neurol (2014) 0.89

Recommendations on screening for cognitive impairment in older adults. CMAJ (2015) 0.87

Treatment for mild cognitive impairment: a systematic review and meta-analysis. CMAJ Open (2015) 0.81

Screening for Mild Cognitive Impairment: Comparison of "MCI Specific" Screening Instruments. J Alzheimers Dis (2016) 0.80

Mediterranean Diet, Cognitive Function, and Dementia: A Systematic Review of the Evidence. Adv Nutr (2016) 0.80

A patient-centered analysis of enrollment and retention in a randomized behavioral trial of two cognitive rehabilitation interventions for Mild Cognitive Impairment. J Prev Alzheimers Dis (2014) 0.79

Cholinesterase inhibitors should not be prescribed for mild cognitive impairment. Evid Based Med (2014) 0.78

Protection against Brain Atrophy by Anti-dementia Medication in Mild Cognitive Impairment and Alzheimer's Disease: Meta-Analysis of Longitudinal Randomized Placebo-Controlled Trials. Int J Neuropsychopharmacol (2015) 0.78

Validation of the Dutch version of the quick mild cognitive impairment screen (Qmci-D). BMC Geriatr (2015) 0.77

Adjunctive treatment for cognitive impairment in patients with chronic schizophrenia: a double-blind, placebo-controlled study. Neuropsychiatr Dis Treat (2014) 0.76

A Prospective Evaluation of Systemic Biomarkers and Cognitive Function Associated with Carotid Revascularization. Ann Surg (2016) 0.75

Utility of social media and crowd-sourced data for pharmacovigilance: a scoping review protocol. BMJ Open (2017) 0.75

Comparing Approaches to Optimize Cut-off Scores for Short Cognitive Screening Instruments in Mild Cognitive Impairment and Dementia. J Alzheimers Dis (2017) 0.75

The case of galantamine: repurposing and late blooming of a cholinergic drug. Future Sci OA (2015) 0.75

Geriatric Psychiatry: What's in a Name, and Five Concerns about DSM-5. Can Geriatr J (2014) 0.75

Articles cited by this

"Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res (1975) 301.74

Meta-analysis in clinical trials. Control Clin Trials (1986) 144.91

Bias in meta-analysis detected by a simple, graphical test. BMJ (1997) 122.24

Quantifying heterogeneity in a meta-analysis. Stat Med (2002) 83.16

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ (2009) 34.99

The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ (2011) 29.14

Global prevalence of dementia: a Delphi consensus study. Lancet (2005) 23.30

The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology (1994) 21.65

A new rating scale for Alzheimer's disease. Am J Psychiatry (1984) 15.16

Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med (2005) 12.04

CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. PLoS Med (2010) 6.88

Advanced methods in meta-analysis: multivariate approach and meta-regression. Stat Med (2002) 6.53

Network meta-analysis for indirect treatment comparisons. Stat Med (2002) 6.32

An inventory to assess activities of daily living for clinical trials in Alzheimer's disease. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord (1997) 5.94

Comparing predictors of conversion and decline in mild cognitive impairment. Neurology (2010) 5.69

An evidence-based practice guideline for the peer review of electronic search strategies. J Clin Epidemiol (2009) 3.98

Effect of rivastigmine on delay to diagnosis of Alzheimer's disease from mild cognitive impairment: the InDDEx study. Lancet Neurol (2007) 3.22

Safety and efficacy of galantamine in subjects with mild cognitive impairment. Neurology (2008) 2.79

Donepezil treatment of patients with MCI: a 48-week randomized, placebo-controlled trial. Neurology (2009) 2.76

Progression of mild cognitive impairment to dementia in clinic- vs community-based cohorts. Arch Neurol (2009) 2.26

Cholinesterase inhibitors for mild cognitive impairment. Cochrane Database Syst Rev (2012) 2.25

Mild cognitive impairment: disparity of incidence and prevalence estimates. Alzheimers Dement (2012) 2.00

Efficacy of donepezil in mild cognitive impairment: a randomized placebo-controlled trial. Neurology (2004) 1.91

Mild cognitive impairment: an epidemiological perspective. Dialogues Clin Neurosci (2004) 1.53

Diagnosis and treatment of dementia: introduction. Introducing a series based on the Third Canadian Consensus Conference on the Diagnosis and Treatment of Dementia. CMAJ (2008) 1.35

Donepezil for mild cognitive impairment. Cochrane Database Syst Rev (2006) 1.27

The Clinician Interview-Based Impression (CIBI): a clinician's global change rating scale in Alzheimer's disease. Neurology (1994) 1.27

Donepezil delays progression to AD in MCI subjects with depressive symptoms. Neurology (2009) 1.20

Progression of mild cognitive impairment to dementia: a challenge to current thinking. Br J Psychiatry (2006) 1.10

Effects of galantamine on working memory and global functioning in patients with mild cognitive impairment: a double-blind placebo-controlled study. Am J Alzheimers Dis Other Demen (2005) 0.97

A double-blind, placebo-controlled trial of memantine in age-associated memory impairment (memantine in AAMI). Int J Geriatr Psychiatry (2007) 0.91

Characteristics and performance of a modified version of the ADCS-CGIC CIBIC+ for mild cognitive impairment clinical trials. Alzheimer Dis Assoc Disord (2009) 0.89

A combination of galantamine and memantine modifies cognitive function in subjects with amnestic MCI. J Nutr Health Aging (2012) 0.85

Donepezil use in US nursing homes. Aging Clin Exp Res (2004) 0.84

A randomized controlled trial of rivastigmine in patients with cognitive impairment no dementia because of cerebrovascular disease. Acta Neurol Scand (2009) 0.82

Use of cognitive enhancers for mild cognitive impairment: protocol for a systematic review and network meta-analysis. Syst Rev (2012) 0.81

Progression from mild cognitive impairment to Alzheimer's disease: effects of sex, butyrylcholinesterase genotype, and rivastigmine treatment. Pharmacogenet Genomics (2009) 0.80

Articles by these authors

Lost in knowledge translation: time for a map? J Contin Educ Health Prof (2006) 18.58

Mentoring in academic medicine: a systematic review. JAMA (2006) 13.66

Epidemiology and reporting characteristics of systematic reviews. PLoS Med (2007) 11.51

Does this patient have delirium?: value of bedside instruments. JAMA (2010) 5.64

Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts. Kidney Int (2011) 5.47

Open letter to the leader of academic medicine. BMJ (2007) 4.06

When laboratories report estimated glomerular filtration rates in addition to serum creatinines, nephrology consults increase. Kidney Int (2009) 3.70

A systematic review of qualitative research on the meaning and characteristics of mentoring in academic medicine. J Gen Intern Med (2009) 3.63

What type of urinary incontinence does this woman have? JAMA (2008) 3.25

Association between glycemic control and adverse outcomes in people with diabetes mellitus and chronic kidney disease: a population-based cohort study. Arch Intern Med (2011) 3.13

Analysis and reporting of factorial trials: a systematic review. JAMA (2003) 3.02

Does this patient have bacterial peritonitis or portal hypertension? How do I perform a paracentesis and analyze the results? JAMA (2008) 2.69

Nocturnal hemodialysis does not improve overall measures of quality of life compared to conventional hemodialysis. Kidney Int (2008) 2.56

Guidelines for the management of chronic kidney disease. CMAJ (2008) 2.54

Synthesis of recommendations for the assessment and management of low back pain from recent clinical practice guidelines. Spine J (2010) 2.54

Efficacy of statins for primary prevention in people at low cardiovascular risk: a meta-analysis. CMAJ (2011) 2.40

A cross-sectional study of the number and frequency of terms used to refer to knowledge translation in a body of health literature in 2006: a Tower of Babel? Implement Sci (2010) 2.38

A comparison of indirect versus direct measures for assessing physical activity in the pediatric population: a systematic review. Int J Pediatr Obes (2009) 2.37

Management of urinary incontinence in women: scientific review. JAMA (2004) 2.37

Effects of self-management intervention on health outcomes of patients with heart failure: a systematic review of randomized controlled trials. BMC Cardiovasc Disord (2006) 2.36

Association between LDL-C and risk of myocardial infarction in CKD. J Am Soc Nephrol (2013) 2.34

Ultrasound monitoring to detect access stenosis in hemodialysis patients: a systematic review. Am J Kidney Dis (2008) 2.24

Stroke: strategies for primary prevention. Am Fam Physician (2003) 2.19

Population based screening for chronic kidney disease: cost effectiveness study. BMJ (2010) 2.19

Canada urgently needs a national network of libraries to access evidence. Healthc Q (2006) 2.07

The 2007 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. Can J Cardiol (2007) 2.01

Measuring quality of care: considering conceptual approaches to quality indicator development and evaluation. J Clin Epidemiol (2013) 2.01

Evidence for quality indicators to evaluate adult trauma care: a systematic review. Crit Care Med (2011) 2.00

Measuring quality of care: considering measurement frameworks and needs assessment to guide quality indicator development. J Clin Epidemiol (2013) 1.99

Benzodiazepines and elderly drivers: a comparison of pharmacoepidemiological study designs. Pharmacoepidemiol Drug Saf (2007) 1.98

Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis. BMC Med (2013) 1.94

Quality indicators for evaluating trauma care: a scoping review. Arch Surg (2010) 1.94

The impact of the electronic medical record on structure, process, and outcomes within primary care: a systematic review of the evidence. J Am Med Inform Assoc (2011) 1.94

Associations among estimated glomerular filtration rate, proteinuria, and adverse cardiovascular outcomes. Clin J Am Soc Nephrol (2011) 1.89

Assessment of thiopurine S-methyltransferase activity in patients prescribed thiopurines: a systematic review. Ann Intern Med (2011) 1.81

Organochlorines and risk of non-Hodgkin lymphoma. Int J Cancer (2007) 1.78

What is the most appropriate knowledge synthesis method to conduct a review? Protocol for a scoping review. BMC Med Res Methodol (2012) 1.75

Changes in survival among elderly patients initiating dialysis from 1990 to 1999. CMAJ (2007) 1.70

Interventions to improve the use of systematic reviews in decision-making by health system managers, policy makers and clinicians. Cochrane Database Syst Rev (2012) 1.66

Measuring agreement of administrative data with chart data using prevalence unadjusted and adjusted kappa. BMC Med Res Methodol (2009) 1.62

Transfer of learning and patient outcome in simulated crisis resource management: a systematic review. Can J Anaesth (2014) 1.60

Evidence based medicine: increasing, not dictating, choice. BMJ (2007) 1.60

A cluster randomized trial of an enhanced eGFR prompt in chronic kidney disease. Clin J Am Soc Nephrol (2012) 1.57

Benefits and harms of erythropoiesis-stimulating agents for anemia related to cancer: a meta-analysis. CMAJ (2009) 1.57

Death and renal transplantation among Aboriginal people undergoing dialysis. CMAJ (2004) 1.56

Association between proximity to the attending nephrologist and mortality among patients receiving hemodialysis. CMAJ (2007) 1.53

Residence location and likelihood of kidney transplantation. CMAJ (2006) 1.49

Exploring mentorship as a strategy to build capacity for knowledge translation research and practice: protocol for a qualitative study. Implement Sci (2009) 1.48

Does this patient have a pleural effusion? JAMA (2009) 1.47

The 2004 Canadian recommendations for the management of hypertension: Part II--Therapy. Can J Cardiol (2004) 1.46

Use of lithium and the risk of injurious motor vehicle crash in elderly adults: case-control study nested within a cohort. BMJ (2004) 1.44

A systematic review identified few methods and strategies describing when and how to update systematic reviews. J Clin Epidemiol (2007) 1.44

Quality-of-care indicators among remote-dwelling hemodialysis patients: a cohort study. Am J Kidney Dis (2013) 1.43

The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 2--therapy. Can J Cardiol (2009) 1.42

Updating systematic reviews: an international survey. PLoS One (2010) 1.41

Histopathologic features aid in predicting risk for progression of IgA nephropathy. Clin J Am Soc Nephrol (2010) 1.39

Exposing the weaknesses: a systematic review of azathioprine efficacy in ulcerative colitis. Dig Dis Sci (2008) 1.38

Association between AKI, recovery of renal function, and long-term outcomes after hospital discharge. Clin J Am Soc Nephrol (2012) 1.37

Understanding the attitudes of the elderly towards enrolment into cancer clinical trials. BMC Cancer (2006) 1.33

The development, evolution, and modifications of ICD-10: challenges to the international comparability of morbidity data. Med Care (2010) 1.27

The knowledge-to-action cycle: identifying the gaps. CMAJ (2009) 1.27

Interventions encouraging the use of systematic reviews by health policymakers and managers: a systematic review. Implement Sci (2011) 1.27

CNODES: the Canadian Network for Observational Drug Effect Studies. Open Med (2012) 1.26

Career development of physician scientists: a survey of leaders in academic medicine. Am J Med (2011) 1.26

The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. Can J Cardiol (2008) 1.25

The impact of severe acute respiratory syndrome on medical house staff: a qualitative study. J Gen Intern Med (2005) 1.24

Impact of a patient decision aid on care among patients with nonvalvular atrial fibrillation: a cluster randomized trial. CMAJ (2005) 1.22

Trace elements in hemodialysis patients: a systematic review and meta-analysis. BMC Med (2009) 1.21

An economic evaluation of erythropoiesis-stimulating agents in CKD. Am J Kidney Dis (2010) 1.20

The impact of leadership training programs on physicians in academic medical centers: a systematic review. Acad Med (2013) 1.19

Following 411 Cochrane protocols to completion: a retrospective cohort study. PLoS One (2008) 1.19

Clinical decision support tools for osteoporosis disease management: a systematic review of randomized controlled trials. J Gen Intern Med (2008) 1.19

Knowledge translation: resolving the confusion. J Contin Educ Health Prof (2006) 1.17

The effects of nocturnal compared with conventional hemodialysis on mineral metabolism: A randomized-controlled trial. Hemodial Int (2009) 1.17

NASS Contemporary Concepts in Spine Care: spinal manipulation therapy for acute low back pain. Spine J (2010) 1.15

Guidelines for randomized clinical trial protocol content: a systematic review. Syst Rev (2012) 1.15

Chronic disease and falls in community-dwelling Canadians over 65 years old: a population-based study exploring associations with number and pattern of chronic conditions. BMC Geriatr (2014) 1.14

Clinical trials and novel pathogens: lessons learned from SARS. Emerg Infect Dis (2004) 1.14

Factors associated with the subspecialty choices of internal medicine residents in Canada. BMC Med Educ (2008) 1.13

Hospital at home: home-based end of life care. Cochrane Database Syst Rev (2011) 1.13

Reporting of the estimated glomerular filtration rate was associated with increased use of angiotensin-converting enzyme inhibitors and angiotensin-II receptor blockers in CKD. Kidney Int (2012) 1.13

The capture-mark-recapture technique can be used as a stopping rule when searching in systematic reviews. J Clin Epidemiol (2008) 1.12

Systematic review and evaluation of web-accessible tools for management of diabetes and related cardiovascular risk factors by patients and healthcare providers. J Am Med Inform Assoc (2012) 1.12

The role of global risk assessment in hypertension therapy. Can J Cardiol (2006) 1.12

Outcomes after acute myocardial infarction in South Asian, Chinese, and white patients. Circulation (2010) 1.11

Balance assessment practices and use of standardized balance measures among Ontario physical therapists. Phys Ther (2011) 1.11

Understanding the relationship between the perceived characteristics of clinical practice guidelines and their uptake: protocol for a realist review. Implement Sci (2011) 1.10

Search filters can find some but not all knowledge translation articles in MEDLINE: an analytic survey. J Clin Epidemiol (2012) 1.10

Similar outcomes among black and white renal allograft recipients. J Am Soc Nephrol (2008) 1.07

Usability evaluation of a clinical decision support tool for osteoporosis disease management. Implement Sci (2010) 1.06

Temporal risk profile for infectious and noninfectious complications of hemodialysis access. J Am Soc Nephrol (2013) 1.05

Usability of a mobile electronic medical record prototype: a verbal protocol analysis. Inform Health Soc Care (2008) 1.05

What's the E for EBM? BMJ (2004) 1.05

Management of urinary incontinence in women: clinical applications. JAMA (2004) 1.03

Group differences in physician responses to handheld presentation of clinical evidence: a verbal protocol analysis. BMC Med Inform Decis Mak (2007) 1.03

A systematic review of recent clinical practice guidelines on the diagnosis, assessment and management of hypertension. PLoS One (2013) 1.01