PubRank

F Heffron

Author PubWeight™ 221.38‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc Natl Acad Sci U S A 1986 14.31
2 DNA sequence analysis of the transposon Tn3: three genes and three sites involved in transposition of Tn3. Cell 1979 13.52
3 Translocation of a plasmid DNA sequence which mediates ampicillin resistance: molecular nature and specificity of insertion. Proc Natl Acad Sci U S A 1975 9.20
4 Origin of the TEM-beta-lactamase gene found on plasmids. J Bacteriol 1975 8.70
5 A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cells. Science 1989 7.58
6 Shuttle mutagenesis: a method of transposon mutagenesis for Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 1986 5.75
7 Deletions affecting the transposition of an antibiotic resistance gene. Proc Natl Acad Sci U S A 1977 5.48
8 In vitro mutagenesis of a circular DNA molecule by using synthetic restriction sites. Proc Natl Acad Sci U S A 1978 5.32
9 Induction of Salmonella stress proteins upon infection of macrophages. Science 1990 5.30
10 A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae. Cell 1983 5.05
11 Ethanolamine utilization in Salmonella typhimurium: nucleotide sequence, protein expression, and mutational analysis of the cchA cchB eutE eutJ eutG eutH gene cluster. J Bacteriol 1995 4.74
12 Intracellular survival of wild-type Salmonella typhimurium and macrophage-sensitive mutants in diverse populations of macrophages. Infect Immun 1989 4.63
13 Salmonella typhimurium phoP virulence gene is a transcriptional regulator. Proc Natl Acad Sci U S A 1989 4.62
14 Transposition of a plasmid deoxyribonucleic acid sequence that mediates ampicillin resistance: independence from host rec functions and orientation of insertion. J Bacteriol 1976 4.13
15 The E. coli gene encoding heat stable toxin is a bacterial transposon flanked by inverted repeats of IS1. Nature 1979 3.94
16 Analysis of sequences transposed by complementation of two classes of transposition-deficient mutants of Tn3. J Bacteriol 1978 3.69
17 Epithelial cell surfaces induce Salmonella proteins required for bacterial adherence and invasion. Science 1989 3.55
18 A 24-base-pair DNA sequence from the MAT locus stimulates intergenic recombination in yeast. Proc Natl Acad Sci U S A 1986 3.40
19 Salmonella typhimurium loci involved in survival within macrophages. Infect Immun 1994 3.32
20 Double-strand breaks stimulate alternative mechanisms of recombination repair. J Mol Biol 1989 3.23
21 Resistance to host antimicrobial peptides is necessary for Salmonella virulence. Proc Natl Acad Sci U S A 1992 2.99
22 DNA sequence of a plasmid-encoded dihydrofolate reductase. Mol Gen Genet 1981 2.98
23 Identification of the protein encoded by the transposable element Tn3 which is required for its transposition. Nature 1980 2.97
24 Recombination-deficient mutants of Salmonella typhimurium are avirulent and sensitive to the oxidative burst of macrophages. Mol Microbiol 1993 2.91
25 A cytolysin encoded by Salmonella is required for survival within macrophages. Proc Natl Acad Sci U S A 1994 2.87
26 Inhibition of macrophage phagosome-lysosome fusion by Salmonella typhimurium. Infect Immun 1991 2.83
27 Macrophage killing is an essential virulence mechanism of Salmonella typhimurium. Proc Natl Acad Sci U S A 1996 2.81
28 The lpf fimbrial operon mediates adhesion of Salmonella typhimurium to murine Peyer's patches. Proc Natl Acad Sci U S A 1996 2.69
29 The Neisseria meningitidis haemoglobin receptor: its role in iron utilization and virulence. Mol Microbiol 1995 2.52
30 Salmonella SsrB activates a global regulon of horizontally acquired genes. Mol Microbiol 2000 2.50
31 Identification of a new iron regulated locus of Salmonella typhi. Gene 1996 2.46
32 The product of the HO gene is a nuclease: purification and characterization of the enzyme. Cold Spring Harb Symp Quant Biol 1984 2.36
33 Salmonella SirA is a global regulator of genes mediating enteropathogenesis. Mol Microbiol 1999 2.33
34 Identification and sequence analysis of lpfABCDE, a putative fimbrial operon of Salmonella typhimurium. J Bacteriol 1995 2.27
35 SdiA of Salmonella enterica is a LuxR homolog that detects mixed microbial communities. J Bacteriol 2001 2.23
36 Invasion and replication of Salmonella typhimurium in animal cells. Infect Immun 1990 2.19
37 Fur regulon of Salmonella typhimurium: identification of new iron-regulated genes. J Bacteriol 1995 2.12
38 The pef fimbrial operon of Salmonella typhimurium mediates adhesion to murine small intestine and is necessary for fluid accumulation in the infant mouse. Infect Immun 1996 2.04
39 HRR25, a putative protein kinase from budding yeast: association with repair of damaged DNA. Science 1991 2.00
40 Shuttle mutagenesis of Neisseria gonorrhoeae: pilin null mutations lower DNA transformation competence. J Bacteriol 1990 2.00
41 Synergistic effect of mutations in invA and lpfC on the ability of Salmonella typhimurium to cause murine typhoid. Infect Immun 1997 1.98
42 Molecular genetic analysis of the Escherichia coli phoP locus. J Bacteriol 1992 1.92
43 IroN, a novel outer membrane siderophore receptor characteristic of Salmonella enterica. J Bacteriol 1998 1.87
44 Salmonella typhimurium encodes an SdiA homolog, a putative quorum sensor of the LuxR family, that regulates genes on the virulence plasmid. J Bacteriol 1998 1.85
45 Contribution of fimbrial operons to attachment to and invasion of epithelial cell lines by Salmonella typhimurium. Infect Immun 1996 1.79
46 Contribution of TonB- and Feo-mediated iron uptake to growth of Salmonella typhimurium in the mouse. Infect Immun 1996 1.77
47 Method for the genetic labeling of cryptic plasmids. J Bacteriol 1978 1.69
48 Multiple fimbrial adhesins are required for full virulence of Salmonella typhimurium in mice. Infect Immun 1998 1.69
49 Role of Salmonella typhimurium Mn-superoxide dismutase (SodA) in protection against early killing by J774 macrophages. Infect Immun 1995 1.67
50 Salmonella pathogenicity island 1-independent induction of apoptosis in infected macrophages by Salmonella enterica serotype typhimurium. Infect Immun 2000 1.65
51 Replication of the nonconjugative plasmid RSF1010 in Escherichia coli K-12. J Bacteriol 1978 1.62
52 In vivo analysis of the Saccharomyces cerevisiae HO nuclease recognition site by site-directed mutagenesis. Mol Cell Biol 1990 1.58
53 Two replication initiation sites on R-plasmid DNA. Mol Gen Genet 1975 1.54
54 Contribution of horizontal gene transfer and deletion events to development of distinctive patterns of fimbrial operons during evolution of Salmonella serotypes. J Bacteriol 1997 1.49
55 Identification of a transposon Tn3 sequence required for transposition immunity. Proc Natl Acad Sci U S A 1983 1.47
56 Rapid detection of Salmonella enterica with primers specific for iroB. J Clin Microbiol 1997 1.45
57 Transposon Tn3 encodes a site-specific recombination system: identification of essential sequences, genes, and actual site of recombination. Proc Natl Acad Sci U S A 1981 1.44
58 Shuttle mutagenesis: bacterial transposons for genetic manipulations in yeast. Methods Enzymol 1991 1.33
59 Identification of three highly attenuated Salmonella typhimurium mutants that are more immunogenic and protective in mice than a prototypical aroA mutant. Infect Immun 1998 1.20
60 Analysis of Tn3 sequences required for transposition and immunity. Gene 1986 1.20
61 The virulence plasmid of Salmonella typhimurium is self-transmissible. J Bacteriol 1999 1.20
62 Cloning and expression of a Serpula (Treponema) hyodysenteriae hemolysin gene. Infect Immun 1992 1.19
63 At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice. Infect Immun 1998 1.17
64 Transposition of a plasmid deoxyribonucleic acid sequence that mediates ampicillin resistance: identity of laboratory-constructed plasmids and clinical isolates. J Bacteriol 1977 1.16
65 Electron microscope heteroduplex studies of sequence relationships among plasmids of the W incompatibility group. Plasmid 1979 1.15
66 Fimbrial adhesins of Salmonella typhimurium. Role in bacterial interactions with epithelial cells. Adv Exp Med Biol 1997 1.11
67 Plasmid cointegrates and their resolution mediated by transposon Tn3 mutants. Gene 1981 1.11
68 Tn3 encodes a site-specific recombination system: identification of essential sequences, genes, and the actual site of recombination. Cold Spring Harb Symp Quant Biol 1981 1.04
69 Isolation of Salmonella mutants defective for intracellular survival. Methods Enzymol 1994 0.98
70 Mosaic structure of the smpB-nrdE intergenic region of Salmonella enterica. J Bacteriol 1998 0.95
71 Induction of SIV capsid-specific CTL and mucosal sIgA in mice immunized with a recombinant S. typhimurium aroA mutant. Vaccine 1996 0.95
72 Transposon Tn5 mutagenesis of Brucella abortus. Infect Immun 1987 0.93
73 A Tn3 derivative that can be used to make short in-frame insertions within genes. Proc Natl Acad Sci U S A 1991 0.90
74 Live bacterial vaccines and their application as carriers for foreign antigens. Adv Vet Sci Comp Med 1989 0.87
75 Cloning and characterization of a cytotoxin gene from Salmonella typhimurium. Res Microbiol 1991 0.87
76 To sting or be stung: bacteria-induced apoptosis. Trends Microbiol 1997 0.87
77 Recombinant, attenuated Salmonella typhimurium stimulate lymphoproliferative responses to SIV capsid antigen in rhesus macaques. Vaccine 1999 0.86
78 The identification of exported proteins with gene fusions to invasin. Mol Microbiol 1998 0.82
79 Mutagenesis and variant selection in Salmonella. Methods Cell Biol 1994 0.81
80 Two-dimensional 1H NMR studies of 32-base-pair synthetic immobile Holliday junctions: complete assignments of the labile protons and identification of the base-pairing scheme. Biochemistry 1993 0.78
81 Synthesis and characterization of a recombinant myohemerythrin protein encoded by a synthetic gene. Gene 1991 0.78
82 Insertion mutations affecting transposition of Tn3 and replication of a ColE1 derivative. Cold Spring Harb Symp Quant Biol 1979 0.78
83 Identification of bacterial class I accessible proteins by disseminated insertion of class I epitopes. Methods Enzymol 2000 0.77
84 The effects of two acylcoenzyme A: cholesterol acyltransferase (ACAT) inhibitors, cyclandelate and a non-hydrolysable ether analogue, benzyl3,3,5-trimethylcyclohexanol on low density lipoprotein metabolism in macrophages and hepatocytes. Biochem Pharmacol 1994 0.75
85 Chemical synthesis of dual-radiolabelled cyclandelate and its metabolism in rat hepatocytes and mouse J774 cells. Xenobiotica 1990 0.75
86 Two-dimensional 1H NMR studies of synthetic immobile Holliday junctions. Biochemistry 1991 0.75
87 Identification of exported bacterial proteins via gene fusions to Yersinia pseudotuberculosis invasin. Methods Enzymol 2000 0.75