Published in J Med Chem on October 23, 2013
Antiviral perspectives for chikungunya virus. Biomed Res Int (2014) 0.92
Discovery of in silico hits targeting the nsP3 macro domain of chikungunya virus. J Mol Model (2014) 0.82
Inhibition of Chikungunya Virus-Induced Cell Death by Salicylate-Derived Bryostatin Analogues Provides Additional Evidence for a PKC-Independent Pathway. J Nat Prod (2016) 0.79
Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death. J Nat Prod (2016) 0.77
Computational Approach Towards Exploring Potential Anti-Chikungunya Activity of Selected Flavonoids. Sci Rep (2016) 0.77
Chikungunya virus (CHIKV) inhibitors from natural sources: a medicinal chemistry perspective. J Nat Med (2015) 0.76
Clinical Spectrum of Chikungunya in Pakistan. Cureus (2017) 0.75
Chikungunya: a re-emerging virus. Lancet (2011) 3.73
Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes. Lancet Infect Dis (2010) 2.24
Characterization of Ross River virus tropism and virus-induced inflammation in a mouse model of viral arthritis and myositis. J Virol (2006) 1.73
Atroposelective synthesis of axially chiral biaryl compounds. Angew Chem Int Ed Engl (2005) 1.61
Differential induction of type I interferon responses in myeloid dendritic cells by mosquito and mammalian-cell-derived alphaviruses. J Virol (2006) 1.57
Eosinophils contribute to innate antiviral immunity and promote clearance of respiratory syncytial virus. Blood (2007) 1.52
Macrophage-derived proinflammatory factors contribute to the development of arthritis and myositis after infection with an arthrogenic alphavirus. J Infect Dis (2008) 1.48
Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness. J Immunol (2006) 1.40
Complement contributes to inflammatory tissue destruction in a mouse model of Ross River virus-induced disease. J Virol (2007) 1.17
Protection from arthritis and myositis in a mouse model of acute chikungunya virus disease by bindarit, an inhibitor of monocyte chemotactic protein-1 synthesis. J Infect Dis (2011) 1.12
Arthritogenic alphaviral infection perturbs osteoblast function and triggers pathologic bone loss. Proc Natl Acad Sci U S A (2014) 1.10
Amelioration of alphavirus-induced arthritis and myositis in a mouse model by treatment with bindarit, an inhibitor of monocyte chemotactic proteins. Arthritis Rheum (2009) 1.10
Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of phytochemicals and biological activities. J Ethnopharmacol (2011) 1.10
The medicinal chemistry of dengue fever. J Med Chem (2009) 1.08
Control of hepatitis C: a medicinal chemistry perspective. J Med Chem (2005) 1.03
The immunobiology of viral arthritides. Pharmacol Ther (2009) 1.02
Revealing indigenous Indonesian traditional medicine: anti-infective agents. Nat Prod Commun (2011) 1.02
Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice. J Virol (2006) 1.00
Call to action for dengue vaccine failure. Emerg Infect Dis (2013) 1.00
Critical role for macrophage migration inhibitory factor (MIF) in Ross River virus-induced arthritis and myositis. Proc Natl Acad Sci U S A (2011) 0.97
Ethnobotanical authentication and identification of Khrog-sman (Lower Elevation Medicinal Plants) of Bhutan. J Ethnopharmacol (2011) 0.96
The molecular and cellular aspects of arthritis due to alphavirus infections: lesson learned from Ross River virus. Ann N Y Acad Sci (2007) 0.94
Mannose binding lectin is required for alphavirus-induced arthritis/myositis. PLoS Pathog (2012) 0.92
Phenylpropanoids and furanocoumarins as antibacterial and antimalarial constituents of the Bhutanese medicinal plant Pleurospermum amabile. Nat Prod Commun (2014) 0.92
GC/GC-MS analysis, isolation and identification of bioactive essential oil components from the Bhutanese medicinal plant, Pleurospermum amabile. Nat Prod Commun (2013) 0.91
A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain. J Ethnopharmacol (2013) 0.90
An assessment of the Bhutanese traditional medicine for its ethnopharmacology, ethnobotany and ethnoquality: Textual understanding and the current practices. J Ethnopharmacol (2013) 0.89
Dengue vaccine efficacy trial: does interference cause failure? Lancet Infect Dis (2013) 0.89
Phytochemical and biological activity studies of the Bhutanese medicinal plant Corydalis crispa. Nat Prod Commun (2012) 0.88
Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia. J Ethnopharmacol (2012) 0.88
Binaphthyl-based dicationic peptoids with therapeutic potential. Angew Chem Int Ed Engl (2010) 0.88
Inhibition of TNF-α production in LPS-activated THP-1 monocytic cells by the crude extracts of seven Bhutanese medicinal plants. J Ethnopharmacol (2013) 0.88
Interleukin 6, RANKL, and osteoprotegerin expression by chikungunya virus-infected human osteoblasts. J Infect Dis (2012) 0.88
Antibody-dependent enhancement and vaccine development. Expert Rev Vaccines (2006) 0.87
Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse model. Virology (2010) 0.87
Downregulation of interferon-β in antibody-dependent enhancement of dengue viral infections of human macrophages is dependent on interleukin-6. J Infect Dis (2011) 0.83
Disease exacerbation by etanercept in a mouse model of alphaviral arthritis and myositis. Arthritis Rheum (2011) 0.82
Macrophage migration inhibitory factor receptor CD74 mediates alphavirus-induced arthritis and myositis in murine models of alphavirus infection. Arthritis Rheum (2013) 0.82
Sphingosine kinase 1 in viral infections. Rev Med Virol (2012) 0.82
Discovery of in silico hits targeting the nsP3 macro domain of chikungunya virus. J Mol Model (2014) 0.82
Anilinopyrimidines as novel antituberculosis agents. Bioorg Med Chem Lett (2003) 0.81
Pulmonary infection of mice with human metapneumovirus induces local cytotoxic T-cell and immunoregulatory cytokine responses similar to those seen with human respiratory syncytial virus. J Gen Virol (2010) 0.81
Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 1. Bioorg Med Chem (2010) 0.80
Dengue virus therapeutic intervention strategies based on viral, vector and host factors involved in disease pathogenesis. Pharmacol Ther (2012) 0.80
Synthesis of novel N-protected hydrophobic phenylalanines and their application in potential antibacterials. Eur J Med Chem (2008) 0.80
Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 2. Bioorg Med Chem (2010) 0.80
Synthesis, molecular modeling and biological activity of methyl and thiomethyl substituted pyrimidines as corticotropin releasing hormone type 1 antagonists. Org Biomol Chem (2003) 0.80
Molecular and cellular mechanisms in the viral exacerbation of asthma. Microbes Infect (2008) 0.79
siRNA against the G gene of human metapneumovirus. Virol J (2012) 0.79
Rapid cascade synthesis of poly-heterocyclic architectures from indigo. J Org Chem (2013) 0.79
Human metapneumovirus establishes persistent infection in the lungs of mice and is reactivated by glucocorticoid treatment. J Virol (2009) 0.78
Synthesis and antibacterial activity of C2-symmetric binaphthyl scaffolded amino acid derivatives. Eur J Med Chem (2011) 0.78
Mining the Chemical Abstracts database with pharmacophore-based queries. J Mol Graph Model (2002) 0.78
Applications of animal models of infectious arthritis in drug discovery: a focus on alphaviral disease. Curr Drug Targets (2011) 0.77
Structure based design towards the identification of novel binding sites and inhibitors for the chikungunya virus envelope proteins. J Mol Graph Model (2013) 0.77
New anti-malarial compounds from database searching. Bioorg Med Chem Lett (2002) 0.77
Methotrexate treatment causes early onset of disease in a mouse model of Ross River virus-induced inflammatory disease through increased monocyte production. PLoS One (2013) 0.76
Combining structure-based drug design and pharmacophores. J Mol Graph Model (2005) 0.76
Synthesis and in vitro binding of N,N-dialkyl-2-phenylindol-3-yl-glyoxylamides for the peripheral benzodiazepine binding sites. Bioorg Med Chem (2006) 0.75
Binaphthyl-anchored antibacterial tripeptide derivatives with hydrophobic C-terminal amino acid variations. Beilstein J Org Chem (2012) 0.75
The discovery of allyltyrosine based tripeptides as selective inhibitors of the HIV-1 integrase strand-transfer reaction. Org Biomol Chem (2016) 0.75
Synthesis of reaction-ready 6,6'-biindole and 6,6'-biisatin via palladium(II)-catalysed intramolecular C-H functionalisation. Chem Commun (Camb) (2010) 0.75
Fullerene van der Waals oligomers as electron traps. J Am Chem Soc (2014) 0.75
Binaphthyl-1,2,3-triazole peptidomimetics with activity against Clostridium difficile and other pathogenic bacteria. Org Biomol Chem (2015) 0.75
A mild and general method for the synthesis of 5-substituted and 5,5-disubstituted fulleroprolines. Org Lett (2008) 0.75
The synthesis and testing of arenearylpyrimidylmethanes as antimalarial agents. ChemMedChem (2006) 0.75
A new methodology for the simulation of flexible protein-ligand interactions. J Mol Graph Model (2006) 0.75
Antarctic Moss Biflavonoids Show High Antioxidant and Ultraviolet-Screening Activity. J Nat Prod (2017) 0.75
Ring-opening and -expansion of 2,2'-biaziridine: access to diverse enantiopure linear and bicyclic vicinal diamines. Org Lett (2014) 0.75
Binaphthyl scaffolded peptoids via ring-closing metathesis reactions and their anti-bacterial activities. Bioorg Med Chem Lett (2009) 0.75
Structural reassignment of the mono- and bis-addition products from the addition reactions of N-(Diphenylmethylene)glycinate esters to [60]fullerene under Bingel conditions. J Org Chem (2005) 0.75
Synthesis and antibacterial activity of some binaphthyl-supported macrocycles containing a cationic amino acid. Bioorg Med Chem (2011) 0.75
Synthesis and characterization of mono- and bis-methano[60]fullerenyl amino acid derivatives and their reductive ring-opening retro-bingel reactions. J Org Chem (2002) 0.75
Bioactive glycosides from the African medicinal plant Boerhavia erecta L. Nat Prod Res (2015) 0.75
The first syntheses of enantiopure 2,2'-biindoline. Chem Commun (Camb) (2010) 0.75
Synthesis and in vitro evaluation of tetrahydroisoquinolines with pendent aromatics as sigma-2 (σ2) selective ligands. Org Biomol Chem (2013) 0.75
Synthesis and antimicrobial activity of binaphthyl-based, functionalized oxazole and thiazole peptidomimetics. Org Biomol Chem (2015) 0.75