Human primary immunodeficiencies causing defects in innate immunity.

I-L-C-2 it: type 2 immunity and group 2 innate lymphoid cells in homeostasis. Curr Opin Immunol (2014) 0.85

Toll-like receptor signaling in primary immune deficiencies. Ann N Y Acad Sci (2015) 0.79

Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science (2006) 2.38

Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients. J Clin Invest (2010) 1.93

Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells. PLoS One (2010) 1.66

Detection of a novel nonsense mutation in the interleukin 2 receptor gamma gene causing X-linked severe combined immunodeficiency. Ann Allergy Asthma Immunol (2006) 1.39

Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome. J Allergy Clin Immunol (2010) 1.36

Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease. J Immunol (2008) 1.11

Common human Toll-like receptor 4 polymorphisms--role in susceptibility to respiratory syncytial virus infection and functional immunological relevance. Clin Immunol (2007) 1.06

IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells. J Immunol (2006) 1.04

Prevalence of Toll-like receptor signalling defects in apparently healthy children who developed invasive pneumococcal infection. Clin Immunol (2006) 1.03

IL-4Rα on CD4+ T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates. J Leukoc Biol (2013) 1.01

Rescue of dysfunctional autophagy attenuates hyperinflammatory responses from cystic fibrosis cells. J Immunol (2012) 1.01

Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children. J Immunol (2014) 1.00

The Pseudomonas aeruginosa autoinducer 3O-C12 homoserine lactone provokes hyperinflammatory responses from cystic fibrosis airway epithelial cells. PLoS One (2011) 1.00

Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis, and bronchopulmonary dysplasia. J Immunol (2013) 0.98

TLR5 as an anti-inflammatory target and modifier gene in cystic fibrosis. J Immunol (2010) 0.97

Inflammasome-mediated IL-1β production in humans with cystic fibrosis. PLoS One (2012) 0.95

Early outcomes and improvement of patients with juvenile idiopathic arthritis enrolled in a Canadian multicenter inception cohort. Arthritis Care Res (Hoboken) (2010) 0.95

Rituximab therapy for multisystem autoimmune diseases in pediatric patients. J Pediatr (2003) 0.95

Atypical activation of the unfolded protein response in cystic fibrosis airway cells contributes to p38 MAPK-mediated innate immune responses. J Immunol (2012) 0.94

Variables to be controlled in the assessment of blood innate immune responses to Toll-like receptor stimulation. J Immunol Methods (2011) 0.94

Predictors of early inactive disease in a juvenile idiopathic arthritis cohort: results of a Canadian multicenter, prospective inception cohort study. Arthritis Rheum (2009) 0.92

Hierarchical maturation of innate immune defences in very preterm neonates. Neonatology (2014) 0.90

Role of human TLR4 in respiratory syncytial virus-induced NF-κB activation, viral entry and replication. Innate Immun (2012) 0.88

Epidemiology of asthma: risk factors for development. Expert Rev Clin Immunol (2009) 0.88

TLR4 Asp299Gly and Thr399Ile polymorphisms: no impact on human immune responsiveness to LPS or respiratory syncytial virus. PLoS One (2010) 0.87

Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis. ACS Chem Biol (2013) 0.87

Influence of common non-synonymous Toll-like receptor 4 polymorphisms on bronchopulmonary dysplasia and prematurity in human infants. PLoS One (2012) 0.87

Workplace violence-a survey of diagnostic radiographers working in public hospitals in Hong Kong. J Occup Health (2009) 0.86

Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge. Pediatr Allergy Immunol (2003) 0.85

Neonatal pain-related stress and NFKBIA genotype are associated with altered cortisol levels in preterm boys at school age. PLoS One (2013) 0.85

Recurrent systemic pneumococcal disease and IRAK4 deficiency. Pediatr Infect Dis J (2007) 0.84

Toll-like receptor signaling and pre-eclampsia. Am J Reprod Immunol (2010) 0.84

Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes. Eur J Immunol (2014) 0.83

Functional analysis of the impact of ORMDL3 expression on inflammation and activation of the unfolded protein response in human airway epithelial cells. Allergy Asthma Clin Immunol (2013) 0.82

Pathogen recognition receptor crosstalk in respiratory syncytial virus sensing: a host and cell type perspective. Trends Microbiol (2013) 0.82

Eighteen-year follow-up of a patient with cobalamin F disease (cblF): report and review. Am J Med Genet A (2011) 0.80

Acidification-dependent activation of CD1d-restricted natural killer T cells is intact in cystic fibrosis. Immunology (2010) 0.80

The Serine Protease Autotransporter Pic Modulates Citrobacter rodentium Pathogenesis and Its Innate Recognition by the Host. Infect Immun (2015) 0.79

Optimizing outcomes of hematopoietic stem cell transplantation for severe combined immunodeficiency. Clin Immunol (2009) 0.79

Primary immune deficiencies presenting in adults: seven years of experience from Iran. J Clin Immunol (2005) 0.79

Severe combined immunodeficiency (SCID) in Canadian children: a national surveillance study. J Clin Immunol (2013) 0.79

Toll-like receptor gene polymorphisms and preeclampsia risk: a case-control study and data synthesis. Hypertens Pregnancy (2010) 0.78

Perinatal Exposure to Traffic-Related Air Pollution and Atopy at 1 Year of Age in a Multi-Center Canadian Birth Cohort Study. Environ Health Perspect (2015) 0.78

Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function. J Clin Invest (2016) 0.77

Commonly invasive serotypes of Streptococcus pneumoniae trigger a reduced innate immune response compared with serotypes rarely responsible for invasive infection. FEMS Immunol Med Microbiol (2008) 0.77

Relative CD4 lymphopenia and a skewed memory phenotype are the main immunologic abnormalities in a child with Omenn syndrome due to homozygous RAG1-C2633T hypomorphic mutation. Clin Immunol (2009) 0.77

Churg-Strauss syndrome in a 7-year-old receiving montelukast and inhaled corticosteroids. Ann Allergy Asthma Immunol (2003) 0.76

A new exposure metric for traffic-related air pollution? An analysis of determinants of hopanes in settled indoor house dust. Environ Health (2013) 0.76

Amino Acid-Dependent Attenuation of Toll-like Receptor Signaling by Peptide-Gold Nanoparticle Hybrids. ACS Nano (2015) 0.75

The challenge of periodic fevers in children. Paediatr Child Health (2012) 0.75

Staphylococcus aureus nasal septal abscess complicated by extradural abscess in an infant. J Otolaryngol Head Neck Surg (2012) 0.75