PubRank

M J Dunne

Author PubWeight™ 61.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene. Nat Genet 2000 2.87
2 Loss of functional KATP channels in pancreatic beta-cells causes persistent hyperinsulinemic hypoglycemia of infancy. Nat Med 1996 2.40
3 Intracellular ADP activates K+ channels that are inhibited by ATP in an insulin-secreting cell line. FEBS Lett 1986 2.06
4 ATP maintains ATP-inhibited K+ channels in an operational state. Pflugers Arch 1986 1.76
5 High-conductance K+ channel in pancreatic islet cells can be activated and inactivated by internal calcium. J Membr Biol 1985 1.58
6 ATP-sensitive inward rectifier and voltage- and calcium-activated K+ channels in cultured pancreatic islet cells. J Membr Biol 1985 1.50
7 Factors associated with the safety of EMS helicopters. Am J Emerg Med 1991 1.43
8 Purification of cytochrome b-245 from human neutrophils. Biochem J 1984 1.36
9 A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland. Diabetes 1999 1.27
10 Activators of protein kinase C depolarize insulin-secreting cells by closing K+ channels. EMBO J 1988 1.25
11 A human T-cell antigen receptor beta chain gene maps to chromosome 7. EMBO J 1984 1.24
12 Quinine inhibits Ca2+-independent K+ channels whereas tetraethylammonium inhibits Ca2+-activated K+ channels in insulin-secreting cells. FEBS Lett 1985 1.16
13 Ionic control of beta cell function in nesidioblastosis. A possible therapeutic role for calcium channel blockade. Arch Dis Child 1996 1.14
14 The alpha 2-adrenoceptor antagonist efaroxan modulates K+ATP channels in insulin-secreting cells. Eur J Pharmacol 1991 1.14
15 Hyperinsulinemic hypoglycemia in Beckwith-Wiedemann syndrome due to defects in the function of pancreatic beta-cell adenosine triphosphate-sensitive potassium channels. J Clin Endocrinol Metab 2005 1.14
16 The contribution of rapid KATP channel gene mutation analysis to the clinical management of children with congenital hyperinsulinism. Eur J Endocrinol 2011 1.06
17 Flight physiology. Clinical considerations. Crit Care Clin 1992 1.05
18 GTP and GDP activation of K+ channels that can be inhibited by ATP. Pflugers Arch 1986 1.05
19 ATP-sensitive K+ channels in an insulin-secreting cell line are inhibited by D-glyceraldehyde and activated by membrane permeabilization. J Membr Biol 1986 1.03
20 Voltage-activated Ca2+ currents in insulin-secreting cells. FEBS Lett 1985 1.01
21 Integrating genetic and imaging investigations into the clinical management of congenital hyperinsulinism. Clin Endocrinol (Oxf) 2013 0.98
22 Transcripts from an aberrantly re-arranged human T-cell receptor beta-chain gene. EMBO J 1985 0.96
23 Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy. J Biol Chem 1999 0.96
24 Glucose activates both K(ATP) channel-dependent and K(ATP) channel-independent signaling pathways in human islets. Diabetes 1998 0.96
25 Therapy for persistent hyperinsulinemic hypoglycemia of infancy. Understanding the responsiveness of beta cells to diazoxide and somatostatin. J Clin Invest 1997 0.95
26 Regulation of K+ channels plays a crucial role in the control of insulin secretion. Pflugers Arch 1989 0.92
27 Vasopressin directly closes ATP-sensitive potassium channels evoking membrane depolarization and an increase in the free intracellular Ca2+ concentration in insulin-secreting cells. EMBO J 1989 0.92
28 Extracellular ATP causes Ca2(+)-dependent and -independent insulin secretion in RINm5F cells. Phospholipase C mediates Ca2+ mobilization but not Ca2+ influx and membrane depolarization. J Biol Chem 1991 0.92
29 Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways. Diabetes 2001 0.92
30 Hyperinsulinism of infancy: towards an understanding of unregulated insulin release. European Network for Research into Hyperinsulinism in Infancy. Arch Dis Child Fetal Neonatal Ed 2000 0.91
31 Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+. Diabetes 2000 0.89
32 Properties of diazoxide and cromakalim-induced activation of potassium channels in cultured rat and RINm5F insulin-secreting cells; effects of GTP. Exp Physiol 1993 0.89
33 ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line. Diabetes 1999 0.88
34 Intra-arterial calcium stimulation test in the investigation of hyperinsulinaemic hypoglycaemia. Arch Dis Child 1998 0.88
35 Ions and genes in persistent hyperinsulinaemic hypoglycaemia in infancy: a commentary on the implications for tailoring treatment to disease pathogenesis. J Pediatr Endocrinol Metab 1998 0.88
36 Congenital hyperinsulinism and mosaic abnormalities of the ploidy. J Med Genet 2005 0.87
37 Glucose augmentation of mastoparan-stimulated insulin secretion in rat and human pancreatic islets. Diabetes 1998 0.87
38 Glucose regulates islet amyloid polypeptide gene transcription in a PDX1- and calcium-dependent manner. J Biol Chem 2000 0.86
39 ATP-induced intracellular Ca2+ signals in isolated human insulin-secreting cells. Pflugers Arch 1994 0.85
40 Human pancreatic acinar cells: studies of stimulus-secretion coupling. Gastroenterology 1985 0.85
41 Characterisation of new efaroxan derivatives for use in purification of imidazoline-binding sites. Eur J Pharmacol 1998 0.85
42 Regulation of intracellular Ca2+ in response to muscarinic and glutamate receptor agonists during the differentiation of NTERA2 human embryonal carcinoma cells into neurons. Eur J Neurosci 1996 0.84
43 Glucokinase activators: molecular tools for studying the physiology of insulin-secreting cells. Biochem Soc Trans 2007 0.84
44 Polymyxin B has multiple blocking actions on the ATP-sensitive potassium channel in insulin-secreting cells. Pflugers Arch 1994 0.83
45 The effect of SMS 201-995, a long-acting somatostatin analogue, on anterior pituitary function in healthy male volunteers. Scand J Gastroenterol Suppl 1986 0.83
46 Uncontrolled insulin secretion from a childhood pancreatic beta-cell adenoma is not due to the functional loss of ATP-sensitive potassium channels. Endocr Relat Cancer 2002 0.82
47 Affinity isolation of imidazoline binding proteins from rat brain using 5-amino-efaroxan as a ligand. FEBS Lett 1999 0.82
48 Network analysis: a new approach to study endocrine disorders. J Mol Endocrinol 2013 0.79
49 Misleading hyponatraemia in acute pancreatitis with hyperlipaemia. Lancet 1979 0.79
50 Effects of 5-hydroxydecanoate on ATP-regulated potassium ion channels in insulin secreting cells. Biochem Soc Trans 1993 0.79
51 Peripheral channelopathies as targets for potassium channel openers. Expert Opin Investig Drugs 2001 0.78
52 Modulation of three types of potassium selective channels by NAD and other pyridine nucleotides in human pancreatic beta-cells. NAD and K+ channels in human beta-cells. Adv Exp Med Biol 1997 0.78
53 Nomifensine test for investigation of hyperprolactinaemia. Lancet 1979 0.78
54 Verapamil, a phenylalkylamine Ca2+ channel blocker, inhibits ATP-sensitive K+ channels in insulin-secreting cells from rats. Diabetologia 1997 0.78
55 Synthesis and characterization of a quinolinonic compound activating ATP-sensitive K(+) channels in endocrine and smooth muscle tissues. Br J Pharmacol 2001 0.77
56 Characterization of purinergic receptor-evoked increases in intracellular Ca2+ transients in isolated human and rodent insulin-secreting cells. Purinergic receptor signalling and [Ca2+]i in human beta-cells. Adv Exp Med Biol 1997 0.77
57 Sulfonylurea receptor 1 and Kir6.2 expression in the novel human insulin-secreting cell line NES2Y. Diabetes 2000 0.77
58 Electronystagmographic findings in long-term low-dose quinine ingestion. A preliminary report. Arch Otolaryngol 1984 0.77
59 Messenger-mediated control of potassium channels in secretory cells. J Exp Biol 1986 0.76
60 Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: implications for stimulus-response coupling of insulin release. Br J Pharmacol 1996 0.76
61 Inhibition of K-channels in insulin secreting cells. Adv Exp Med Biol 1986 0.75
62 Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochem Soc Trans 1994 0.75
63 Administration of high-dose octreotide (Sandostatin) by continuous subcutaneous infusion for the treatment of acromegaly. Horm Res 1990 0.75
64 Blockade of K+ channels in insulin-secreting cells by the 'potassium channel opener' SDZ PCO 400. Biochem Soc Trans 1993 0.75
65 Elevation of intracellular calcium signals in single isolated somatostatin-secreting cells derived from a pancreatic endocrine tumour. Biochem Soc Trans 1993 0.75
66 Novel actions of the potassium channel modulator SDZ PCO 400 on ATP-regulated potassium channels in insulin secreting cells. SDZ PCO 400 and beta-cells. Adv Exp Med Biol 1997 0.75
67 Insulinotropic effect of new glibenclamide isosteres. J Pharmacol Exp Ther 1999 0.75
68 Voltage-activated Ca2+ and K+ currents in an insulin-secreting cell line (RINm5F). Adv Exp Med Biol 1986 0.75
69 Validation of the CALSPAN gross-motion-simulation code with actually occurring injury patterns in aircraft accidents. Aviat Space Environ Med 1978 0.75
70 Intracellular Ca2+ signals in human-derived pancreatic somatostatin-secreting cells (QGP-1N). Pflugers Arch 1994 0.75
71 Opioid-mediated inhibition of oxytocin during insulin-induced hypoglycemic stimulation of vasopressin in man. Acta Endocrinol (Copenh) 1988 0.75
72 Joint Committee on Aviation Pathology: XV. Medical investigation of fatalities from aircraft-accident burns. Aviat Space Environ Med 1977 0.75
73 Agonist-evoked, repetitive calcium transients in human-derived pancreatic somatostatin-secreting cells (QGP-1N). Biochem Soc Trans 1993 0.75
74 Activation of potassium channels by diazoxide and cromakalim in insulin-secreting cells is dependent upon internal ADP and channel run-down. Biochem Soc Trans 1993 0.75
75 Protein kinase C and the modulation of ATP-sensitive potassium channels in insulin-secreting cells. Biochem Soc Trans 1993 0.75
76 Interaction of diazoxide and cromakalim with ATP-regulated K+ channels in rodent and clonal insulin-secreting cells. J Mol Endocrinol 1993 0.75