Published in BMC Syst Biol on October 20, 2013
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Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology (2006) 7.06
Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene (2006) 6.61
MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells. Hepatology (2009) 2.57
Genetic induction of proinflammatory immunity in children with biliary atresia. Lancet (2002) 2.44
Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-gamma in experimental biliary atresia. J Clin Invest (2004) 2.40
NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses. PLoS Pathog (2009) 2.32
Group A rotaviruses produce extrahepatic biliary obstruction in orally inoculated newborn mice. Pediatr Res (1993) 2.22
The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology (2008) 2.17
Neonatal NK cells target the mouse duct epithelium via Nkg2d and drive tissue-specific injury in experimental biliary atresia. J Clin Invest (2009) 2.08
The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma. J Hepatol (2008) 1.88
Binding of NF-kappaB p65 subunit to the promoter elements is involved in LPS-induced transactivation of miRNA genes in human biliary epithelial cells. Nucleic Acids Res (2010) 1.81
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The pathogenesis of biliary atresia: evidence for a virus-induced autoimmune disease. Semin Liver Dis (2007) 1.74
New aspects in a murine model for extrahepatic biliary atresia. J Pediatr Surg (1997) 1.66
Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia. Gastroenterology (2007) 1.62
Down-regulation of the microRNAs miR-34a, miR-127, and miR-200b in rat liver during hepatocarcinogenesis induced by a methyl-deficient diet. Mol Carcinog (2009) 1.61
Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease. Lab Invest (2010) 1.60
Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice. Lab Invest (2010) 1.59
Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis. Hepatology (2012) 1.55
MicroRNA-193b regulates proliferation, migration and invasion in human hepatocellular carcinoma cells. Eur J Cancer (2010) 1.37
miR-30 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in hepatocyte by targeting Snail1. Biochem Biophys Res Commun (2011) 1.25
Biliary atresia: will blocking inflammation tame the disease? Annu Rev Med (2011) 1.23
Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation. J Cell Physiol (2011) 1.19
MicroRNA profiling identifies miR-29 as a regulator of disease-associated pathways in experimental biliary atresia. J Pediatr Gastroenterol Nutr (2012) 1.18
Hepatitis C virus proteins modulate microRNA expression and chemosensitivity in malignant hepatocytes. Clin Cancer Res (2010) 1.17
The histone deacetylase 4/SP1/microrna-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma. Hepatology (2011) 1.17
Analysis of the biliary transcriptome in experimental biliary atresia. Gastroenterology (2005) 1.13
Alterations in microRNA expression profile in HCV-infected hepatoma cells: involvement of miR-491 in regulation of HCV replication via the PI3 kinase/Akt pathway. Biochem Biophys Res Commun (2011) 1.09
Cholangiocyte expression of alpha2beta1-integrin confers susceptibility to rotavirus-induced experimental biliary atresia. Am J Physiol Gastrointest Liver Physiol (2008) 1.07
miRNA regulation of liver growth after 50% partial hepatectomy and small size grafts in rats. Transplantation (2011) 1.01
miRNA-195 sensitizes human hepatocellular carcinoma cells to 5-FU by targeting BCL-w. Oncol Rep (2011) 0.95
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An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets. Genome Biol (2003) 4.49
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. Nature (2011) 4.34
Pattern of sequence variation across 213 environmental response genes. Genome Res (2004) 3.93
Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. EMBO J (2004) 3.32
Disease candidate gene identification and prioritization using protein interaction networks. BMC Bioinformatics (2009) 3.03
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biol (2007) 2.70
Improved human disease candidate gene prioritization using mouse phenotype. BMC Bioinformatics (2007) 2.56
Atlas of gene expression in the developing kidney at microanatomic resolution. Dev Cell (2008) 2.44
Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation. J Clin Invest (2014) 2.31
Coordinate expression of regulatory genes differentiates embryonic and perinatal forms of biliary atresia. Hepatology (2004) 2.28
Gene expression signature for biliary atresia and a role for interleukin-8 in pathogenesis of experimental disease. Hepatology (2014) 2.20
MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways. Sci Transl Med (2012) 2.20
Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays. Mol Cell Biol (2004) 2.19
Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease. Nature (2009) 2.05
Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis. Proc Natl Acad Sci U S A (2007) 1.86
Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues. Cancer Res (2006) 1.80
Dendritic cells regulate natural killer cell activation and epithelial injury in experimental biliary atresia. Sci Transl Med (2011) 1.79
ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems. Nucleic Acids Res (2010) 1.75
IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice. Hepatology (2014) 1.69
Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death. J Mol Cell Cardiol (2010) 1.66
Genetic variants in SCN5A promoter are associated with arrhythmia phenotype severity in patients with heterozygous loss-of-function mutation. Heart Rhythm (2012) 1.51
Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene. EMBO Mol Med (2009) 1.41
Drug repositioning for orphan diseases. Brief Bioinform (2011) 1.37
Novel resequencing chip customized to diagnose mutations in patients with inherited syndromes of intrahepatic cholestasis. Gastroenterology (2006) 1.35
Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case study. PLoS Comput Biol (2011) 1.26
Defining the cellular target(s) of porcine reproductive and respiratory syndrome virus blocking monoclonal antibody 7G10. J Virol (2006) 1.26
Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system. BMC Genomics (2004) 1.25
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways. J Clin Invest (2014) 1.24
Dynamic interaction between T cell-mediated beta-cell damage and beta-cell repair in the run up to autoimmune diabetes of the NOD mouse. Physiol Genomics (2005) 1.19
Dissecting microregulation of a master regulatory network. BMC Genomics (2008) 1.18
GenomeTrafac: a whole genome resource for the detection of transcription factor binding site clusters associated with conventional and microRNA encoding genes conserved between mouse and human gene orthologs. Nucleic Acids Res (2006) 1.17
Growth inhibition and apoptosis in liver myofibroblasts promoted by hepatocyte growth factor leads to resolution from liver cirrhosis. Am J Pathol (2005) 1.17
PhenoHM: human-mouse comparative phenome-genome server. Nucleic Acids Res (2010) 1.16
Novel genes and functional relationships in the adult mouse gastrointestinal tract identified by microarray analysis. Gastroenterology (2002) 1.15
Post-natal paucity of regulatory T cells and control of NK cell activation in experimental biliary atresia. J Hepatol (2010) 1.14
Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype. J Clin Invest (2011) 1.13
Analysis of the biliary transcriptome in experimental biliary atresia. Gastroenterology (2005) 1.13
Inferring novel disease indications for known drugs by semantically linking drug action and disease mechanism relationships. BMC Bioinformatics (2009) 1.12
Wnt/Lrp/beta-catenin signaling suppresses adipogenesis by inhibiting mutual activation of PPARgamma and C/EBPalpha. Biochem Biophys Res Commun (2007) 1.10
Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity. J Clin Invest (2013) 1.08
Clinical phenotype and endocrinological investigations in a patient with a mutation in the MCT8 thyroid hormone transporter. Eur J Pediatr (2007) 1.05
Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats. Circulation (2004) 1.04
Identification of new p53 target microRNAs by bioinformatics and functional analysis. BMC Cancer (2013) 1.02
Temporal-spatial activation of apoptosis and epithelial injury in murine experimental biliary atresia. Hepatology (2008) 1.01
Macrophages are targeted by rotavirus in experimental biliary atresia and induce neutrophil chemotaxis by Mip2/Cxcl2. Pediatr Res (2010) 1.00
Staging of biliary atresia at diagnosis by molecular profiling of the liver. Genome Med (2010) 0.99
Microarray-based discovery of highly expressed olfactory mucosal genes: potential roles in the various functions of the olfactory system. Physiol Genomics (2003) 0.99
Neural system-enriched gene expression: relationship to biological pathways and neurological diseases. Physiol Genomics (2004) 0.96
Decidual cell polyploidization necessitates mitochondrial activity. PLoS One (2011) 0.94
Mining FDA drug labels for medical conditions. BMC Med Inform Decis Mak (2013) 0.94
Loss of interleukin-12 modifies the pro-inflammatory response but does not prevent duct obstruction in experimental biliary atresia. BMC Gastroenterol (2006) 0.94
The orphan disease networks. Am J Hum Genet (2011) 0.92
Replication of a GWAS signal in a Caucasian population implicates ADD3 in susceptibility to biliary atresia. Hum Genet (2013) 0.92
Expansion of prominin-1-expressing cells in association with fibrosis of biliary atresia. Hepatology (2014) 0.91
Heat shock improves Sca-1+ stem cell survival and directs ischemic cardiomyocytes toward a prosurvival phenotype via exosomal transfer: a critical role for HSF1/miR-34a/HSP70 pathway. Stem Cells (2014) 0.91
miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients. J Neurooncol (2015) 0.90
STAT3 genotypic variation and cellular STAT3 activation and colon leukocyte recruitment in pediatric Crohn disease. J Pediatr Gastroenterol Nutr (2012) 0.90
Mast cell transcriptional networks. Blood Cells Mol Dis (2008) 0.90
Identifying disease-causal genes using Semantic Web-based representation of integrated genomic and phenomic knowledge. J Biomed Inform (2008) 0.90
Differential colonization with segmented filamentous bacteria and Lactobacillus murinus do not drive divergent development of diet-induced obesity in C57BL/6 mice. Mol Metab (2013) 0.89
Silencing or amplification of endocannabinoid signaling in blastocysts via CB1 compromises trophoblast cell migration. J Biol Chem (2012) 0.88
Regression based predictor for p53 transactivation. BMC Bioinformatics (2009) 0.88
Chemical-protein interactome and its application in off-target identification. Interdiscip Sci (2011) 0.86
Hepatic to pancreatic switch defines a role for hemostatic factors in cellular plasticity in mice. Proc Natl Acad Sci U S A (2005) 0.85
Multimodal therapy including liver transplantation for hepatic undifferentiated embryonal sarcoma. Liver Transpl (2013) 0.85
Recombinant hepatocyte growth factor accelerates cutaneous wound healing in a diabetic mouse model. Growth Factors (2004) 0.84
Computational drug repositioning through heterogeneous network clustering. BMC Syst Biol (2013) 0.84
Integrative systems biology approaches to identify and prioritize disease and drug candidate genes. Methods Mol Biol (2011) 0.83
Molecular engineering and validation of an oncolytic herpes simplex virus type 1 transcriptionally targeted to midkine-positive tumors. J Gene Med (2010) 0.82
A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBP-J/Su(H) in modulating the pathological outcome. Hum Mol Genet (2011) 0.82
Computational approaches for human disease gene prediction and ranking. Adv Exp Med Biol (2014) 0.82
A vertex similarity-based framework to discover and rank orphan disease-related genes. BMC Syst Biol (2012) 0.81
PU.1 positively regulates GATA-1 expression in mast cells. J Immunol (2010) 0.81
Intractable itch relieved by 4-phenylbutyrate therapy in patients with progressive familial intrahepatic cholestasis type 1. Orphanet J Rare Dis (2014) 0.80
PDX-1/Hes-1 interactions determine cholangiocyte proliferative response to injury in rodents: possible implications for sclerosing cholangitis. J Hepatol (2012) 0.79
Lack of guanylate cyclase C results in increased mortality in mice following liver injury. BMC Gastroenterol (2010) 0.79
Pancreatic Duodenal Homeobox-1 de novo expression drives cholangiocyte neuroendocrine-like transdifferentiation. J Hepatol (2010) 0.78
Mining human phenome to investigate modularity of complex disorders. Summit on Translat Bioinforma (2008) 0.78
Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout. Physiol Genomics (2013) 0.78
An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance. Oncoimmunology (2012) 0.77
Novel mechanism of cyclic AMP mediated extracellular signal regulated kinase activation in an intestinal cell line. Cell Signal (2007) 0.77
Cystic Biliary Atresia and Choledochal Cysts are Distinct Histopathologic Entities. Am J Surg Pathol (2017) 0.76
Major role of apolipoprotein B in cycloheximide-induced acute hepatic steatosis in mice. Hepatol Res (2011) 0.76
Reply: To PMID 24493287. Hepatology (2014) 0.75