Published in J Hum Hypertens on October 24, 2013
Aliskiren Effect on Aortic Plaque Progression (ALPINE) | NCT01417104
Lipid changes due to fenofibrate treatment are not associated with changes in DNA methylation patterns in the GOLDN study. Front Genet (2015) 0.77
Role of MicroRNAs in Renin-Angiotensin-Aldosterone System-Mediated Cardiovascular Inflammation and Remodeling. Int J Inflam (2015) 0.76
Epigenetic modulation in the treatment of atherosclerotic disease. Front Genet (2014) 0.75
Peripheral leukocyte microRNAs as novel biomarkers for COPD. Int J Chron Obstruct Pulmon Dis (2017) 0.75
Most mammalian mRNAs are conserved targets of microRNAs. Genome Res (2008) 37.16
Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med (2000) 29.25
Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet (2002) 23.18
Direct multiplexed measurement of gene expression with color-coded probe pairs. Nat Biotechnol (2008) 15.90
Effect of torcetrapib on the progression of coronary atherosclerosis. N Engl J Med (2007) 6.79
Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res (2008) 4.95
Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling. Cancer Res (2008) 3.01
Retracted MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts. J Biol Chem (2006) 2.62
Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: a unifying hypothesis. Hypertension (2001) 2.61
The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer. Oncogene (2012) 1.95
Renin inhibitor aliskiren improves impaired nitric oxide bioavailability and protects against atherosclerotic changes. Hypertension (2008) 1.81
Renin inhibition reduces hypercholesterolemia-induced atherosclerosis in mice. J Clin Invest (2008) 1.70
Baseline characteristics in the Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE). J Renin Angiotensin Aldosterone Syst (2012) 1.68
Identifying functional microRNAs in macrophages with polarized phenotypes. J Biol Chem (2012) 1.67
Aliskiren inhibits atherosclerosis development and improves plaque stability in APOE*3Leiden.CETP transgenic mice with or without treatment with atorvastatin. J Hypertens (2012) 1.50
Gene expression profiling reveals renin mRNA overexpression in human hypertensive kidneys and a role for microRNAs. Hypertension (2011) 1.36
miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy. J Biol Chem (2010) 1.34
Vascular microRNAs. Curr Drug Targets (2010) 1.34
Circulating miRNA profiles in patients with metabolic syndrome. J Clin Endocrinol Metab (2012) 1.31
Renin inhibition with aliskiren: where are we now, and where are we going? J Hypertens (2006) 1.18
The role of transforming growth factor-beta in atherosclerosis. Cytokine Growth Factor Rev (2006) 1.09
A new look at the renin-angiotensin system--focusing on the vascular system. Peptides (2011) 1.08
Attenuation of exogenous angiotensin II stress-induced damage and apoptosis in human vascular endothelial cells via microRNA-155 expression. Int J Mol Med (2012) 1.05
SNPs in microRNA binding sites in 3'-UTRs of RAAS genes influence arterial blood pressure and risk of myocardial infarction. Am J Hypertens (2011) 1.03
MiR-106b promotes cell proliferation via targeting RB in laryngeal carcinoma. J Exp Clin Cancer Res (2011) 0.99
MicroRNAs miR-124 and miR-135a are potential regulators of the mineralocorticoid receptor gene (NR3C2) expression. Biochem Biophys Res Commun (2009) 0.99
T1-weighted-SPACE dark blood whole body magnetic resonance angiography (DB-WBMRA): initial experience. J Magn Reson Imaging (2010) 0.97
MiR-106b and MiR-15b modulate apoptosis and angiogenesis in myocardial infarction. Cell Physiol Biochem (2012) 0.95
Initial feasibility of a multi-station high resolution three-dimensional dark blood angiography protocol for the assessment of peripheral arterial disease. J Magn Reson Imaging (2009) 0.83
Renin inhibitors. J Clin Hypertens (Greenwich) (2011) 0.79
Aliskiren effect on plaque progression in established atherosclerosis using high resolution 3D MRI (ALPINE): a double-blind placebo-controlled trial. J Am Heart Assoc (2013) 0.79