|
1
|
Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.
|
Gastroenterology
|
2006
|
2.43
|
|
2
|
Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.
|
Mol Pharmacol
|
2008
|
2.11
|
|
3
|
Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy.
|
Blood
|
2011
|
1.77
|
|
4
|
Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs.
|
J Clin Pharmacol
|
2007
|
1.56
|
|
5
|
Peroxisome proliferator-activated receptor δ agonist GW1516 attenuates diet-induced aortic inflammation, insulin resistance, and atherosclerosis in low-density lipoprotein receptor knockout mice.
|
Arterioscler Thromb Vasc Biol
|
2013
|
1.47
|
|
6
|
Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants.
|
Pharmacogenet Genomics
|
2007
|
1.39
|
|
7
|
Identification of novel functional organic anion-transporting polypeptide 1B3 polymorphisms and assessment of substrate specificity.
|
Pharmacogenet Genomics
|
2011
|
1.24
|
|
8
|
Pharmacogenomics of the OATP and OAT families.
|
Pharmacogenomics
|
2004
|
1.21
|
|
9
|
Pharmacogenetics of ATP-binding cassette transporters in cancer and chemotherapy.
|
Mol Cancer Ther
|
2003
|
1.16
|
|
10
|
CYP3A4 and seasonal variation in vitamin D status in addition to CYP2D6 contribute to therapeutic endoxifen level during tamoxifen therapy.
|
Breast Cancer Res Treat
|
2013
|
1.13
|
|
11
|
Human skeletal muscle drug transporters determine local exposure and toxicity of statins.
|
Circ Res
|
2009
|
1.04
|
|
12
|
Interplay between the nuclear receptor pregnane X receptor and the uptake transporter organic anion transporter polypeptide 1A2 selectively enhances estrogen effects in breast cancer.
|
Cancer Res
|
2008
|
1.04
|
|
13
|
Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe.
|
Pharmacogenet Genomics
|
2008
|
1.03
|
|
14
|
A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
|
Drug Metab Dispos
|
2007
|
1.02
|
|
15
|
Pharmacokinetics and safety of intravenously administered citrulline in children undergoing congenital heart surgery: potential therapy for postoperative pulmonary hypertension.
|
J Thorac Cardiovasc Surg
|
2007
|
1.02
|
|
16
|
The human proton-coupled folate transporter (hPCFT): modulation of intestinal expression and function by drugs.
|
Am J Physiol Gastrointest Liver Physiol
|
2009
|
0.95
|
|
17
|
Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care.
|
Circ Cardiovasc Genet
|
2013
|
0.95
|
|
18
|
A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression.
|
Mol Endocrinol
|
2007
|
0.94
|
|
19
|
Clinical and genetic determinants of warfarin pharmacokinetics and pharmacodynamics during treatment initiation.
|
PLoS One
|
2011
|
0.90
|
|
20
|
Genotype-guided dosing of vitamin K antagonists.
|
N Engl J Med
|
2014
|
0.88
|
|
21
|
Clarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet response.
|
Eur Heart J
|
2012
|
0.86
|
|
22
|
Determination of the Pharmacokinetics and Oral Bioavailability of Salicylamine, a Potent γ-Ketoaldehyde Scavenger, by LC/MS/MS.
|
Pharmaceutics
|
2010
|
0.84
|
|
23
|
Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.
|
Mol Pharm
|
2009
|
0.82
|
|
24
|
Segmental intestinal transporters and metabolic enzymes on intestinal drug absorption.
|
Drug Metab Dispos
|
2003
|
0.81
|
|
25
|
Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis.
|
Hepatology
|
2011
|
0.80
|
|
26
|
Interaction of three regiospecific amino acid residues is required for OATP1B1 gain of OATP1B3 substrate specificity.
|
Mol Pharm
|
2012
|
0.79
|
|
27
|
Case report: atenolol overdose successfully treated with hemodialysis.
|
Hemodial Int
|
2013
|
0.79
|
|
28
|
Vascular binding, blood flow, transporter, and enzyme interactions on the processing of digoxin in rat liver.
|
J Pharmacol Exp Ther
|
2005
|
0.78
|
|
29
|
Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2.
|
Hepatology
|
2002
|
0.77
|
|
30
|
Pharmacokinetics of prednisolone at steady state in young patients with systemic lupus erythematosus on prednisone therapy: an open-label, single-dose study.
|
Clin Ther
|
2011
|
0.77
|
|
31
|
Beyond CAR and PXR.
|
Curr Drug Metab
|
2005
|
0.77
|
|
32
|
Transport function and transcriptional regulation of a liver-enriched human organic anion transporting polypeptide 2B1 transcriptional start site variant.
|
Mol Pharmacol
|
2013
|
0.76
|
|
33
|
CYP3A4 Activity is Markedly Lower in Patients with Crohn's Disease.
|
Inflamm Bowel Dis
|
2017
|
0.75
|
|
34
|
Ciprofloxacin and rifampin have opposite effects on levothyroxine absorption.
|
Thyroid
|
2013
|
0.75
|
|
35
|
Incremental lowering of low-density lipoprotein cholesterol with ezetimibe 20 mg vs 10 mg daily in patients receiving concomitant statin therapy.
|
Can J Cardiol
|
2013
|
0.75
|