Expression of the senescence marker p16INK4a in skin biopsies of acute lymphoblastic leukemia survivors: a pilot study.

PubWeight™: 0.81‹?›

🔗 View Article (PMC 3827993)

Published in Radiat Oncol on October 31, 2013

Authors

Sophie Marcoux, Oanh N L Le, Chloé Langlois-Pelletier, Caroline Laverdière, Afshin Hatami, Philippe Robaey, Christian M Beauséjour1

Author Affiliations

1: Centre de recherche du CHU Sainte-Justine, Montréal, Québec, Canada. christian.beausejour@recherche-ste-justine.qc.ca.

Articles cited by this

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol (2008) 11.43

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature (2006) 9.20

p16INK4a induces an age-dependent decline in islet regenerative potential. Nature (2006) 9.09

Senescence of activated stellate cells limits liver fibrosis. Cell (2008) 8.98

The regulation of INK4/ARF in cancer and aging. Cell (2006) 8.75

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature (2011) 8.45

Ink4a/Arf expression is a biomarker of aging. J Clin Invest (2004) 8.30

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature (2006) 8.06

Senescence in tumours: evidence from mice and humans. Nat Rev Cancer (2010) 6.34

Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J (2003) 5.61

Aging, cellular senescence, and cancer. Annu Rev Physiol (2012) 5.08

Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01. Blood (2001) 3.93

Clinical ascertainment of health outcomes among adults treated for childhood cancer. JAMA (2013) 3.65

Total body irradiation selectively induces murine hematopoietic stem cell senescence. Blood (2005) 2.82

Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging. Aging Cell (2009) 2.21

Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes. Blood (2011) 2.16

Long-term results of Dana-Farber Cancer Institute ALL Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1985-2000). Leukemia (2009) 1.99

Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells. Cancer Res (2003) 1.86

Cell senescence in rat kidneys in vivo increases with growth and age despite lack of telomere shortening. Kidney Int (2003) 1.85

Postinduction dexamethasone and individualized dosing of Escherichia Coli L-asparaginase each improve outcome of children and adolescents with newly diagnosed acute lymphoblastic leukemia: results from a randomized study--Dana-Farber Cancer Institute ALL Consortium Protocol 00-01. J Clin Oncol (2013) 1.75

Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status. Aging Cell (2010) 1.43

Regulation of E2Fs and senescence by PML nuclear bodies. Genes Dev (2011) 1.25

Challenges after curative treatment for childhood cancer and long-term follow up of survivors. Hematol Oncol Clin North Am (2010) 1.16

p16(INK4a) and the control of cellular proliferative life span. Carcinogenesis (1999) 1.08

Cellular senescence and tissue aging in vivo. J Gerontol A Biol Sci Med Sci (2002) 0.92

Articles by these authors

Erwinia asparaginase after allergy to E. coli asparaginase in children with acute lymphoblastic leukemia. Pediatr Blood Cancer (2010) 1.91

Polymorphisms in multidrug resistance-associated protein gene 4 is associated with outcome in childhood acute lymphoblastic leukemia. Blood (2009) 1.80

Postinduction dexamethasone and individualized dosing of Escherichia Coli L-asparaginase each improve outcome of children and adolescents with newly diagnosed acute lymphoblastic leukemia: results from a randomized study--Dana-Farber Cancer Institute ALL Consortium Protocol 00-01. J Clin Oncol (2013) 1.75

A prospective randomized trial comparing the efficacy and adverse effects of four recognized treatments of molluscum contagiosum in children. Pediatr Dermatol (2006) 1.64

Effectiveness of pamidronate as treatment of symptomatic osteonecrosis occurring in children treated for acute lymphoblastic leukemia. Pediatr Blood Cancer (2012) 1.51

Neuropsychological outcomes from a randomized trial of triple intrathecal chemotherapy compared with 18 Gy cranial radiation as CNS treatment in acute lymphoblastic leukemia: findings from Dana-Farber Cancer Institute ALL Consortium Protocol 95-01. J Clin Oncol (2007) 1.46

Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status. Aging Cell (2010) 1.43

Restraint and cancellation: multiple inhibition deficits in attention deficit hyperactivity disorder. J Abnorm Child Psychol (2007) 1.34

Changes in cardiac biomarkers during doxorubicin treatment of pediatric patients with high-risk acute lymphoblastic leukemia: associations with long-term echocardiographic outcomes. J Clin Oncol (2012) 1.32

The low incidence of secondary acute myelogenous leukaemia in children and adolescents treated with dexrazoxane for acute lymphoblastic leukaemia: a report from the Dana-Farber Cancer Institute ALL Consortium. Eur J Cancer (2011) 1.10

High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy. J Clin Oncol (2012) 1.05

Endocrine late effects of childhood cancer therapy: a report from the Children's Oncology Group. Horm Res (2007) 1.04

Propranolol versus prednisone in the treatment of infantile hemangiomas: a retrospective comparative study. Pediatr Dermatol (2011) 1.03

Malignant melanoma in childhood and adolescence: report of 13 cases. J Am Acad Dermatol (2005) 1.02

Victimization: a newly recognized outcome of prematurity. Dev Med Child Neurol (2004) 1.01

ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia. Blood (2011) 1.01

Targetoid hemosiderotic hemangiomas (hobnail hemangiomas) are vascular lymphatic malformations: a study of 12 pediatric cases. J Am Acad Dermatol (2011) 1.00

Connective tissue nevi in children: institutional experience and review. J Am Acad Dermatol (2012) 0.98

The Quebec Newborn Twin Study into adolescence: 15 years later. Twin Res Hum Genet (2012) 0.97

Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia. Blood (2009) 0.97

Polymorphisms of genes controlling homocysteine levels and IQ score following the treatment for childhood ALL. Pharmacogenomics (2005) 0.94

Virtual navigation strategies from childhood to senescence: evidence for changes across the life span. Front Aging Neurosci (2012) 0.89

Heritability of response inhibition in children. J Int Neuropsychol Soc (2010) 0.89

Treatment of periocular infantile hemangiomas with propranolol: case series of 18 children. Ophthalmology (2011) 0.88

Neuropsychological outcomes of standard risk and high risk patients treated for acute lymphoblastic leukemia on Dana-Farber ALL consortium protocol 95-01 at 5 years post-diagnosis. Pediatr Blood Cancer (2011) 0.88

Adrenocortical functioning in boys with attention-deficit/hyperactivity disorder: examining subtypes of ADHD and associated comorbid conditions. J Abnorm Child Psychol (2009) 0.87

Verbal cognitive functioning and learning in girls treated for acute lymphoblastic leukemia by chemotherapy with or without cranial irradiation. Dev Neuropsychol (2002) 0.87

Continuous Versus Bolus Infusion of Doxorubicin in Children With ALL: Long-term Cardiac Outcomes. Pediatrics (2012) 0.86

How do children with ADHD (mis)manage their real-life dyadic friendships? A multi-method investigation. J Abnorm Child Psychol (2011) 0.86

Late rebound of infantile hemangioma after cessation of oral propranolol. Pediatr Dermatol (2013) 0.85

DNA variants in region for noncoding interfering transcript of dihydrofolate reductase gene and outcome in childhood acute lymphoblastic leukemia. Clin Cancer Res (2009) 0.84

Predictive factors of internalized and externalized behavioral problems in children treated for acute lymphoblastic leukemia. Pediatr Blood Cancer (2012) 0.83

Childhood linear IgA bullous disease induced by trimethoprim-sulfamethoxazole. J Dermatol Case Rep (2010) 0.83

Association of the dopamine transporter gene and ADHD symptoms in a Canadian population-based sample of same-age twins. Am J Med Genet B Neuropsychiatr Genet (2008) 0.82

Prevalence of methylphenidate use and change over a two-year period: a nationwide study of 2- to 11-year-old Canadian children. J Pediatr (2002) 0.81

Large congenital melanocytic nevi and neurocutaneous melanocytosis: one pediatric center's experience. J Am Acad Dermatol (2009) 0.81

Altered patterns of brain activity during transient sadness in children at familial risk for major depression. J Affect Disord (2011) 0.81

Bim polymorphisms: influence on function and response to treatment in children with acute lymphoblastic leukemia. Clin Cancer Res (2013) 0.81

Propranolol in the treatment of problematic infantile hemangioma: review of 35 consecutive patients from a vascular anomalies clinic. J Cutan Med Surg (2012) 0.80

Continuities and changes in the friendships of children with and without ADHD: a longitudinal, observational study. J Abnorm Child Psychol (2013) 0.79

Individual change in methylphenidate use in a national sample of children aged 2 to 11 years. Can J Psychiatry (2005) 0.79

Polymorphisms of the vincristine pathway and response to treatment in children with childhood acute lymphoblastic leukemia. Pharmacogenomics (2014) 0.79

Impact of promoter polymorphisms in key regulators of the intrinsic apoptosis pathway on the outcome of childhood acute lymphoblastic leukemia. Haematologica (2013) 0.78

Pharmacogenetic considerations for acute lymphoblastic leukemia therapies. Expert Opin Drug Metab Toxicol (2014) 0.78

Pharmacogenetics of the neurodevelopmental impact of anticancer chemotherapy. Dev Disabil Res Rev (2008) 0.78

Visuo-motor coordination in 8-year-old children born pre-term before and after 28 weeks of gestation. Dev Neurorehabil (2008) 0.78

Neuropsychological outcomes of a randomized trial of prednisone versus dexamethasone in acute lymphoblastic leukemia: findings from Dana-Farber Cancer Institute All Consortium Protocol 00-01. Pediatr Blood Cancer (2013) 0.78

Imaging of early modification in cardiomyopathy: the doxorubicin-induced model. Int J Cardiovasc Imaging (2013) 0.77

Role of NOS3 DNA variants in externalizing behavioral problems observed in childhood leukemia survivors. J Pediatr Hematol Oncol (2013) 0.77

Contribution of temporal processing skills to reading comprehension in 8-year-olds: evidence for a mediation effect of phonological awareness. Child Dev (2012) 0.76

Anti-IgE therapy and severe atopic dermatitis: a pediatric perspective. J Am Acad Dermatol (2013) 0.76

Therapy of ulcerated hemangiomas. J Cutan Med Surg (2013) 0.75

Response to the letter to the Editor. J Can Acad Child Adolesc Psychiatry (2007) 0.75

Attention-Deficit/Hyperactivity Disorder and the challenges of close friendship. J Can Acad Child Adolesc Psychiatry (2007) 0.75

[The future of psychiatry: scientific research]. Sante Ment Que (2005) 0.75

Assessment of gross motor skills and phenotype profile in children 9-11 years of age in survivors of acute lymphoblastic leukemia. Pediatr Blood Cancer (2013) 0.75

Plexiform fibrohistiocytic tumor in three children. Pediatr Dermatol (2006) 0.75

Diseases of abnormal sensitivity to cold in children on psychostimulant drugs. J Cutan Med Surg (2014) 0.75

Propranolol in the treatment of problematic infantile hemangioma: review of 35 consecutive patients from a vascular anomalies clinic. J Cutan Med Surg (2012) 0.75

Emergent perspectives on ADHD: sharing knowledge and extending care. J Can Acad Child Adolesc Psychiatry (2007) 0.75

Distinguishing features of cuban children referred for professional help because of ADHD: looking beyond the symptoms. J Atten Disord (2010) 0.75

Auditory ERP in extremely premature 5-year-old children. Brain Cogn (2002) 0.75