Published in Curr Neurol Neurosci Rep on December 01, 2013
Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse. Acta Neuropathol Commun (2015) 1.39
Reconsidering harbingers of dementia: progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence. Neurobiol Aging (2014) 1.08
HIV effects on age-associated neurocognitive dysfunction: premature cognitive aging or neurodegenerative disease? Alzheimers Res Ther (2015) 0.89
The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment. Alzheimers Dement (2015) 0.85
Cerebral autoregulation, beta amyloid, and white matter hyperintensities are interrelated. Neurosci Lett (2015) 0.83
White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network. Ann Neurol (2016) 0.82
Cerebral small vessel disease and Alzheimer's disease. Clin Interv Aging (2015) 0.80
Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease. Neurobiol Aging (2016) 0.80
Cerebral white matter lesions - associations with Aβ isoforms and amyloid PET. Sci Rep (2016) 0.77
White matter and cognition: making the connection. J Neurophysiol (2016) 0.76
Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly. Front Aging Neurosci (2015) 0.76
Elevated cerebrovascular resistance index is associated with cognitive dysfunction in the very-old. Alzheimers Res Ther (2015) 0.76
Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant. J Cereb Blood Flow Metab (2016) 0.75
Sleep Disordered Breathing and White Matter Hyperintensities in Community-Dwelling Elders. Sleep (2016) 0.75
Magnetic Resonance Volumetry: Prediction of Subjective Memory Complaints and Mild Cognitive Impairment, and Associations with Genetic and Cardiovascular Risk Factors. Dement Geriatr Cogn Dis Extra (2016) 0.75
Chronotropic Response and Cognitive Function in a Cohort at Risk for Alzheimer's Disease. J Alzheimers Dis (2016) 0.75
Clinical-pathological agreement in dementing disorders: embracing the complexity. Tremor Other Hyperkinet Mov (N Y) (2014) 0.75
Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology (1984) 119.59
Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (1991) 49.03
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.26
Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.02
The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 21.80
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol (2010) 19.42
[11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease. Neurology (2006) 12.10
Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med (2003) 10.61
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol (2013) 9.43
MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging. AJR Am J Roentgenol (1987) 8.48
The projected effect of risk factor reduction on Alzheimer's disease prevalence. Lancet Neurol (2011) 8.15
Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol (2008) 7.95
Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol Aging (1997) 7.54
Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease. Brain (2007) 6.39
Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects. Brain (2008) 6.29
Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan. Neurology (2001) 5.98
Pathologic correlates of incidental MRI white matter signal hyperintensities. Neurology (1993) 5.72
The pathological process underlying Alzheimer's disease in individuals under thirty. Acta Neuropathol (2010) 5.59
Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A (2009) 5.55
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiol Aging (2010) 5.49
Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study. BMJ (2001) 5.40
Cardiovascular risk factors and cognitive decline in middle-aged adults. Neurology (2001) 4.78
Disruption of functional connectivity in clinically normal older adults harboring amyloid burden. J Neurosci (2009) 4.50
Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology (2005) 4.04
The cognitive correlates of white matter abnormalities in normal aging: a quantitative review. Neuropsychology (2000) 3.98
The effect of white matter hyperintensity volume on brain structure, cognitive performance, and cerebral metabolism of glucose in 51 healthy adults. Neurology (1995) 3.95
Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study. Neurology (2001) 3.56
Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort. Am J Epidemiol (2001) 3.43
Extent and distribution of white matter hyperintensities in normal aging, MCI, and AD. Neurology (2006) 3.22
Cerebral white matter lesions and the risk of dementia. Arch Neurol (2004) 3.17
A semiquantative rating scale for the assessment of signal hyperintensities on magnetic resonance imaging. J Neurol Sci (1993) 3.16
Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis. Neuron (2008) 3.08
PIB is a non-specific imaging marker of amyloid-beta (Abeta) peptide-related cerebral amyloidosis. Brain (2007) 2.88
Hyperinsulinemia and risk of Alzheimer disease. Neurology (2004) 2.87
beta-Amyloid-mediated vasoactivity and vascular endothelial damage. Nature (1996) 2.82
Neuropathological basis of magnetic resonance images in aging and dementia. Ann Neurol (2008) 2.71
Aging of cerebral white matter: a review of MRI findings. Int J Geriatr Psychiatry (2009) 2.70
Brain morphology in older African Americans, Caribbean Hispanics, and whites from northern Manhattan. Arch Neurol (2008) 2.69
β-Amyloid burden in healthy aging: regional distribution and cognitive consequences. Neurology (2012) 2.49
Hypertension is related to cognitive impairment: a 20-year follow-up of 999 men. Hypertension (1998) 2.31
The role of cerebral ischemia in Alzheimer's disease. Neurobiol Aging (2000) 2.30
Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging. Stroke (2008) 2.12
Association of midlife blood pressure to late-life cognitive decline and brain morphology. Neurology (1998) 2.09
Progression of white matter lesions and hemorrhages in cerebral amyloid angiopathy. Neurology (2006) 2.06
Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study. Arch Neurol (2008) 2.03
Beta-amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia. Neurology (2010) 1.99
Designing drug trials for Alzheimer's disease: what we have learned from the release of the phase III antibody trials: a report from the EU/US/CTAD Task Force. Alzheimers Dement (2013) 1.98
Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48. Sci Transl Med (2013) 1.97
Measures of adiposity and dementia risk in elderly persons. Arch Neurol (2007) 1.88
Contribution of vascular risk factors to the progression in Alzheimer disease. Arch Neurol (2009) 1.86
Senile dementia of the Binswanger type. A vascular form of dementia in the elderly. JAMA (1987) 1.86
Peripheral Abeta subspecies as risk biomarkers of Alzheimer's disease. Proc Natl Acad Sci U S A (2008) 1.84
Long-term blood pressure fluctuation and cerebrovascular disease in an elderly cohort. Arch Neurol (2010) 1.80
Cortical and leptomeningeal cerebrovascular amyloid and white matter pathology in Alzheimer's disease. Mol Med (2003) 1.79
White matter lesions on magnetic resonance imaging in clinically diagnosed Alzheimer's disease. Evidence for heterogeneity. Brain (1992) 1.77
Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre. Brain (2013) 1.64
Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia. Arch Neurol (2008) 1.60
Exogenous A beta1-40 reproduces cerebrovascular alterations resulting from amyloid precursor protein overexpression in mice. J Cereb Blood Flow Metab (2000) 1.55
Capillary and arterial cerebral amyloid angiopathy in Alzheimer's disease: defining the perivascular route for the elimination of amyloid beta from the human brain. Neuropathol Appl Neurobiol (2003) 1.52
Measuring cerebral atrophy and white matter hyperintensity burden to predict the rate of cognitive decline in Alzheimer disease. Arch Neurol (2008) 1.48
Reduction in cerebral blood flow in areas appearing as white matter hyperintensities on magnetic resonance imaging. Psychiatry Res (2009) 1.48
Lower cardiac output is associated with greater white matter hyperintensities in older adults with cardiovascular disease. J Am Geriatr Soc (2007) 1.47
White matter hyperintensities and cerebral amyloidosis: necessary and sufficient for clinical expression of Alzheimer disease? JAMA Neurol (2013) 1.47
Regional white matter hyperintensity volume, not hippocampal atrophy, predicts incident Alzheimer disease in the community. Arch Neurol (2012) 1.44
Structural neuroimaging in Altheimer's disease: do white matter hyperintensities matter? Dialogues Clin Neurosci (2009) 1.38
Neuropathologic basis of white matter hyperintensity accumulation with advanced age. Neurology (2013) 1.29
Subclinical cerebrovascular disease in mild cognitive impairment. Neurology (2009) 1.28
Periventricular and subcortical hyperintensities on magnetic resonance imaging. 'Rims, caps, and unidentified bright objects'. Arch Neurol (1988) 1.27
Epidemiology of white matter lesions. Top Magn Reson Imaging (2004) 1.26
Quantitative approaches for assessment of white matter hyperintensities in elderly populations. Psychiatry Res (2011) 1.22
Regional distribution of white matter hyperintensities in vascular dementia, Alzheimer's disease and healthy aging. Dement Geriatr Cogn Disord (2004) 1.22
Do white matter changes contribute to the subsequent development of dementia in patients with mild cognitive impairment? A longitudinal study. Int J Geriatr Psychiatry (2000) 1.15
Could Wallerian degeneration contribute to "leuko-araiosis" in subjects free of any vascular disorder? J Neurol Neurosurg Psychiatry (1991) 1.07
Cerebral perfusion is associated with white matter hyperintensities in older adults with heart failure. Congest Heart Fail (2013) 1.07
Hippocampal subregions differentially associate with standardized memory tests. Hippocampus (2010) 1.02
Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress. Arch Med Res (2012) 1.00
Periventricular white matter lucencies in senile dementia of the Alzheimer type and in normal aging. Neurology (1987) 0.99
Stroke risk factors and loss of high cognitive function. Neurology (2004) 0.92
White matter hyperintensities and amyloid are independently associated with entorhinal cortex volume among individuals with mild cognitive impairment. Alzheimers Dement (2013) 0.92
Cerebrovascular disease and the pathophysiology of Alzheimer's disease. Implications for therapy. Panminerva Med (2004) 0.88
Shifting paradigms in dementia: toward stratification of diagnosis and treatment using MRI. Ann N Y Acad Sci (2007) 0.87
Independent and interactive effects of blood pressure and cardiac function on brain volume and white matter hyperintensities in heart failure. J Am Soc Hypertens (2013) 0.82
Lobar brain hemorrhages and white matter changes: Clinical, radiological and laboratorial profiles. Cerebrovasc Dis (2006) 0.82
Metabolic syndrome and localization of white matter hyperintensities in the elderly population. Alzheimers Dement (2012) 0.82
White matter changes in dementia: does radiology matter? Br J Radiol (2007) 0.80
Regional white matter hyperintensity volume and cognition predict death in a multiethnic community cohort of older adults. J Am Geriatr Soc (2013) 0.78