Published in Cell Commun Signal on November 05, 2013
Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness. Nat Commun (2016) 0.85
Curcumin eliminates the effect of advanced glycation end-products (AGEs) on the divergent regulation of gene expression of receptors of AGEs by interrupting leptin signaling. Lab Invest (2014) 0.84
The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus. Oncotarget (2016) 0.79
Intracellular signaling prevents effective blockade of oncogenic gp130 mutants by neutralizing antibodies. Cell Commun Signal (2014) 0.77
STAT2 Is a Pervasive Cytokine Regulator due to Its Inhibition of STAT1 in Multiple Signaling Pathways. PLoS Biol (2016) 0.76
STAT3 Undergoes Acetylation-dependent Mitochondrial Translocation to Regulate Pyruvate Metabolism. Sci Rep (2016) 0.75
Protein stabilization improves STAT3 function in autosomal dominant hyper-IgE syndrome. Blood (2016) 0.75
A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res (2001) 124.61
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Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J (2003) 10.77
STAT3 mutations in the hyper-IgE syndrome. N Engl J Med (2007) 8.99
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci U S A (1997) 7.08
Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature (2007) 7.07
JAK-STAT signaling: from interferons to cytokines. J Biol Chem (2007) 5.28
Three-dimensional structure of the Stat3beta homodimer bound to DNA. Nature (1998) 5.04
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STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J (1999) 4.55
The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu Rev Immunol (2004) 3.76
A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells. EMBO J (1996) 3.40
Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage. Ann Rheum Dis (2011) 2.74
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STATs dimerize in the absence of phosphorylation. J Biol Chem (2003) 1.89
Analysis of Stat3 (signal transducer and activator of transcription 3) dimerization by fluorescence resonance energy transfer in living cells. Biochem J (2004) 1.24
STAT3 forms stable homodimers in the presence of divalent cations prior to activation. Biochem Biophys Res Commun (1998) 1.22
Single-step purification and structural characterization of human interleukin-6 produced in Escherichia coli from a T7 RNA polymerase expression vector. Eur J Biochem (1991) 1.18
Cytokine-induced paracrystals prolong the activity of signal transducers and activators of transcription (STAT) and provide a model for the regulation of protein solubility by small ubiquitin-like modifier (SUMO). J Biol Chem (2011) 1.11
Cytoplasmic STAT proteins associate prior to activation. Biochem J (2000) 1.06
The role of the N-terminal domain in dimerization and nucleocytoplasmic shuttling of latent STAT3. J Cell Sci (2011) 1.05
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STAT3 mutations correlated with hyper-IgE syndrome lead to blockage of IL-6/STAT3 signalling pathway. J Biosci (2012) 0.87
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Consequences of the disease-related L78R mutation for dimerization and activity of STAT3. J Cell Sci (2014) 0.83
Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis. Oncotarget (2014) 0.80
Intracellular signaling prevents effective blockade of oncogenic gp130 mutants by neutralizing antibodies. Cell Commun Signal (2014) 0.77