Alexander Zaika

Author PubWeight™ 35.06‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 p53 has a direct apoptogenic role at the mitochondria. Mol Cell 2003 8.98
2 Glutathione peroxidase 7 has potential tumour suppressor functions that are silenced by location-specific methylation in oesophageal adenocarcinoma. Gut 2013 1.48
3 Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cells. Gastroenterology 2010 1.45
4 Aurora kinase A inhibition leads to p73-dependent apoptosis in p53-deficient cancer cells. Cancer Res 2008 1.37
5 deltaNp73 facilitates cell immortalization and cooperates with oncogenic Ras in cellular transformation in vivo. Mol Cell Biol 2003 1.33
6 The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells. Mol Cancer Ther 2012 1.33
7 Interaction of Helicobacter pylori with gastric epithelial cells is mediated by the p53 protein family. Gastroenterology 2008 1.33
8 Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions. Cancer 2008 1.32
9 Therapeutic prospects for p73 and p63: rising from the shadow of p53. Drug Resist Updat 2008 1.32
10 p53 Family: Role of Protein Isoforms in Human Cancer. J Nucleic Acids 2011 1.26
11 Darpp-32: a novel antiapoptotic gene in upper gastrointestinal carcinomas. Cancer Res 2005 1.19
12 t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism. Cancer Res 2008 1.15
13 Loss of TFF1 is associated with activation of NF-κB-mediated inflammation and gastric neoplasia in mice and humans. J Clin Invest 2011 1.15
14 Expression of tight-junction protein claudin-7 is an early event in gastric tumorigenesis. Am J Pathol 2005 1.11
15 Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses. Proc Natl Acad Sci U S A 2012 1.11
16 Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells. Gut 2011 1.08
17 Overexpression of the 32-kilodalton dopamine and cyclic adenosine 3',5'-monophosphate-regulated phosphoprotein in common adenocarcinomas. Cancer 2003 1.06
18 The combination of alisertib, an investigational Aurora kinase A inhibitor, and docetaxel promotes cell death and reduces tumor growth in preclinical cell models of upper gastrointestinal adenocarcinomas. Cancer 2012 1.04
19 Coamplified and overexpressed genes at ERBB2 locus in gastric cancer. Int J Cancer 2004 0.98
20 Cofactor of BRCA1: a novel transcription factor regulator in upper gastrointestinal adenocarcinomas. Cancer Res 2006 0.95
21 HDM2 regulation by AURKA promotes cell survival in gastric cancer. Clin Cancer Res 2013 0.94
22 Clustering of molecular alterations in gastroesophageal carcinomas. Neoplasia 2004 0.91
23 Proinflammatory cytokines and bile acids upregulate ΔNp73 protein, an inhibitor of p53 and p73 tumor suppressors. PLoS One 2013 0.90
24 Regulation of the p53 by Helicobacter pylori. Oncotarget 2012 0.81